Использование пищевых продуктов на основе растительного белка для коррекции паттернов питания при алиментарно-зависимых заболеваниях: возможности и перспективы - Журнал Терапевтический архив №8 Вопросы лечения 2025

Использование пищевых продуктов на основе растительного белка для коррекции паттернов питания при алиментарно-зависимых заболеваниях: возможности и перспективы

Морозов С.В., Пилипенко В.И., Исаков В.А., Сасунова А.Н., Гончаров А.А., Кочеткова А.А. Использование пищевых продуктов на основе растительного белка для коррекции паттернов питания при алиментарно-зависимых заболеваниях: возможности и перспективы. Терапевтический архив. 2025;97(8):727–734. DOI: 10.26442/00403660.2025.08.203302

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Morozov SV, Pilipenko VI, Isakov VA, Sasunova AN, Goncharov AA, Kochetkova AA. The use of plant protein-based foods for the correction of dietary patterns in alimentary-dependent diseases: opportunities and prospects. A review. Terapevticheskii Arkhiv (Ter. Arkh.). 2025;97(8):727–734. DOI: 10.26442/00403660.2025.08.203302

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Аннотация

Возможности использования пищевых продуктов на основе растительного белка для коррекции паттернов питания при алиментарно-зависимых заболеваниях (АЗЗ) органов пищеварения изучены недостаточно. Целью обзора является анализ данных литературных источников для определения возможностей использования продуктов на основе растительного белка с целью коррекции паттернов питания при наиболее распространенных АЗЗ органов пищеварения. Проведен поиск в базах данных PubMed/Medline, Embase, Google Scholar, CyberLeninka, Elibrary с ключевыми словами, соответствующими целям исследования. Выявлено 314 исследований, однако после исключения дублирующихся публикаций и анализа релевантных данных включены в исследование 66 работ. Результаты анализа показали возможную пользу от использования растительного белка, что может иметь клиническое значение при таких заболеваниях, как метаболически ассоциированная жировая болезнь печени, гастроэзофагеальная рефлюксная болезнь, синдром раздраженного кишечника. Приведены данные об адекватности рационов с включением растительного белка и возможные нежелательные явления при их применении. Затронуты технологические и экономические перспективы использования продуктов на основе растительных белков для коррекции паттернов питания у больных с АЗЗ органов пищеварения.

Ключевые слова: пищевые паттерны, растительный белок, метаболически ассоциированная жировая болезнь печени, гастроэзофагеальная рефлюксная болезнь, синдром раздраженного кишечника

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Idiopathic recurrent pericarditis is a rare pathology characterised by recurrent inflammation in the cardiac cavity. Treatment of recurrent pericarditis is The possibilities of using food products based on vegetable protein to correct nutritional patterns in alimentary-dependent diseases (ADDs) of the digestive system have not been sufficiently studied. The purpose of the review is to analyze the literature data to determine the possibilities of using vegetable protein products to correct nutritional patterns in the most common ADDs of the digestive system. We searched the PubMed/MEDLINE, EMBASE, Google Scholar, CyberLeninka, and Elibrary databases with keywords corresponding to the study goals. There were 314 studies identified; however, after excluding duplicate publications and analyzing relevant data, 66 papers were included. The analysis results showed a possible benefit from using vegetable protein, which may be of clinical importance in diseases such as metabolically associated fatty liver disease, gastroesophageal reflux disease, and irritable bowel syndrome. Data on the adequacy of diets with vegetable protein and possible adverse events during their use are presented. The technological and economic prospects of using products based on vegetable proteins to correct nutritional patterns in patients with ADDs of the digestive system are addressed.

Keywords: nutritional patterns, vegetable protein, metabolically associated fatty liver disease, gastroesophageal reflux disease, irritable bowel syndrome

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1. Teryokhin SP, Akhmetova SV, Molotov-Luchansky VB, et al. Problem of non-infectious alimentary-dependent diseases in the world. Medicine and Ecology. 2018;(2):40-8 (in Russian).
2. Permanyer I, Trias-Llimós S, Spijker JJA. Best-practice healthy life expectancy vs. life expectancy: Catching up or lagging behind? Proc Natl Acad Sci USA. 2021;118(46):e2115273118. DOI:10.1073/pnas.2115273118
3. Riboli E, Hunt KJ, Slimani N, et al. European Prospective Investigation into Cancer and Nutrition (EPIC): study populations and data collection. Public Health Nutr. 2002;5(6B):1113-24. DOI:10.1079/PHN2002394
4. Hughes J, Pearson E, Grafenauer S. Legumes-A Comprehensive Exploration of Global Food-Based Dietary Guidelines and Consumption. Nutrients. 2022;14(15):3080. DOI:10.3390/nu14153080
5. Green A, Blattmann C, Chen C, Mathys A. The role of alternative proteins and future foods in sustainable and contextually-adapted flexitarian diets. Trends in Food Science & Technology. 2022;124:250-5. DOI:10.1016/j.tifs.2022.03.026
6. Curtain F, Grafenauer S. Plant-Based Meat Substitutes in the Flexitarian Age: An Audit of Products on Supermarket Shelves. Nutrients. 2019;11(11):2603. DOI:10.3390/nu11112603
7. Lichtenstein AH, Appel LJ, Vadiveloo M, et al. 2021 Dietary Guidance to Improve Cardiovascular Health: A Scientific Statement From the American Heart Association. Circulation. 2021;144(23):e472-47. DOI:10.1161/CIR.0000000000001031
8. Willett W, Rockström J, Loken B, et al. Food in the Anthropocene: the EAT-Lancet Commission on healthy diets from sustainable food systems. Lancet. 2019;393(10170):447-92. DOI:10.1016/S0140-6736(18)31788-4
9. European Association for the Study of the Liver (EASL), European Association for the Study of Diabetes (EASD), European Association for the Study of Obesity (EASO). EASL-EASD-EASO Clinical Practice Guidelines on the management of metabolic dysfunction-associated steatotic liver disease (MASLD). J Hepatol. 2024;81(3):492-542. DOI:10.1016/j.jhep.2024.04.031
10. Khazaei Y, Dehghanseresht N, Ebrahimi Mousavi S, et al. Association Between Protein Intake From Different Animal and Plant Origins and the Risk of Non-Alcoholic Fatty Liver Disease: A Case-Control Study. Clin Nutr Res. 2023;12(1):29-39. DOI:10.7762/cnr.2023.12.1.29
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Авторы

С.В. Морозов*^1,2, В.И. Пилипенко¹, В.А. Исаков¹, А.Н. Сасунова¹, А.А. Гончаров¹, А.А. Кочеткова¹

¹ФГБУН «Федеральный исследовательский центр питания, биотехнологии и безопасности пищи», Москва, Россия;
²ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России, Москва, Россия
*morosoffsv@mail.ru

________________________________________________

Sergey V. Morozov*^1,2, Vladimir I. Pilipenko¹, Vasily A. Isakov¹, Armida N. Sasunova¹, Alexey A. Goncharov¹, Alla A. Kochetkova¹

¹Federal Research Centre of Nutrition, Biotechnology and Food Safety, Moscow, Russia;
²Russian Medical Academy of Continuous Professional Education, Moscow, Russia
*morosoffsv@mail.ru

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