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        • Новая коронавирусная инфекция COVID-19: экстрапульмональные проявления

        Новая коронавирусная инфекция COVID-19: экстрапульмональные проявления

        Новая коронавирусная инфекция COVID-19: экстрапульмональные проявления

        Маев И.В., Шпектор А.В., Васильева Е.Ю. и др. Новая коронавирусная инфекция COVID-19: экстрапульмональные проявления. Терапевтический архив. 2020; 92 (8). DOI: 10.26442/00403660.2020.08.000767

        ________________________________________________

        Maev I.V., Shpektor A.V., Vasilyeva E.Yu., et al. Novel coronavirus infection COVID-19: extrapulmonary manifestations. Therapeutic Archive. 2020; 92 (8). DOI: 10.26442/00403660.2020.08.000767

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          Новая коронавирусная инфекция COVID-19: экстрапульмональные проявления

        Материалы доступны только для специалистов сферы здравоохранения. Авторизуйтесь или зарегистрируйтесь.

        • Аннотация
        • Авторы
        • Список литературы
        Аннотация
        Новая коронавирусная инфекция COVID-19 в превалирующем большинстве случаев манифестирует респираторными симптомами и лихорадкой, однако у некоторых пациентов могут отмечаться сердечно-сосудистые и гастроэнтерологические проявления. Особенностью клинического синдрома COVID-19 является развитие выраженных иммунопатологических реакций и нарушений гемостаза, ведущее к широкому спектру сердечно-сосудистых осложнений. Течение COVID-19 может осложниться развитием острого инфаркта миокарда, венозных и артериальных тромбозов и тромбоэмболий в различных сосудистых бассейнах, острого повреждения миокарда и миокардита. Среди гастроэнтерологических проявлений наиболее часто выявляются диарея, тошнота или рвота, а также абдоминальная боль. Эти симптомы могут предшествовать появлению респираторных признаков заболевания, а в некоторых случаях выходить на первый план в клинической картине заболевания. Помимо этого, у части больных наблюдаются лабораторные признаки поражения печени (повышение сывороточных трансаминаз). Точный патогенез описанных нарушений продолжает изучаться.

        Ключевые слова: COVID-19, SARS-CoV-2, острый инфаркт миокарда, повреждение миокарда, коагулопатия, тромбоз, острый коронарный синдром, диарея, рвота, абдоминальная боль, потеря аппетита.

        ________________________________________________

        The novel coronavirus infection COVID-19 in most cases manifests with respiratory symptoms and fever, however, some patients may have cardiovascular and gastroenterological manifestations. A feature of the clinical syndrome of COVID-19 is the development of pronounced immunopathological reactions and disorders of hemostasis, leading to the development of a wide range of cardiovascular complications. The course of COVID-19 may be complicated by the development of acute myocardial infarction, venous and arterial thrombosis and thromboembolism in various vascular pools, the development of acute myocardial damage and myocarditis. Among the gastroenterological manifestations, diarrhea, nausea or vomiting, as well as abdominal pain, are most often detected. These symptoms may precede the appearance of respiratory signs of the disease, and in some cases come to the fore in the clinical picture of the disease. In addition, in some patients there are laboratory signs of liver injury (increased serum transaminases). The exact pathogenesis of the above disorders continues to be studied.

        Keywords: COVID-19, SARS-CoV-2, acute myocardial infarction, myocardial damage, coagulopathy, thrombosis, acute coronary syndrome, diarrhea, vomiting, abdominal pain, loss of appetite.

        Авторы
        И.В. Маев, А.В. Шпектор, Е.Ю. Васильева, В.Н. Манчуров, Д.Н. Андреев

        ФГБОУ ВО «Московский государственный медико-стоматологический университет им. А.И. Евдокимова» Минздрава России,
        Москва, Россия

        ________________________________________________

        I.V. Maev, A.V. Shpektor, E.Yu. Vasilyeva, V.N. Manchurov, D.N. Andreev 

        Yevdokimov Moscow State University of Medicine and Dentistry, Moscow, Russia

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