Новая коронавирусная инфекция COVID-19: экстрапульмональные проявления
Новая коронавирусная инфекция COVID-19: экстрапульмональные проявления
Маев И.В., Шпектор А.В., Васильева Е.Ю. и др. Новая коронавирусная инфекция COVID-19: экстрапульмональные проявления. Терапевтический архив. 2020; 92 (8). DOI: 10.26442/00403660.2020.08.000767
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Аннотация
Новая коронавирусная инфекция COVID-19 в превалирующем большинстве случаев манифестирует респираторными симптомами и лихорадкой, однако у некоторых пациентов могут отмечаться сердечно-сосудистые и гастроэнтерологические проявления. Особенностью клинического синдрома COVID-19 является развитие выраженных иммунопатологических реакций и нарушений гемостаза, ведущее к широкому спектру сердечно-сосудистых осложнений. Течение COVID-19 может осложниться развитием острого инфаркта миокарда, венозных и артериальных тромбозов и тромбоэмболий в различных сосудистых бассейнах, острого повреждения миокарда и миокардита. Среди гастроэнтерологических проявлений наиболее часто выявляются диарея, тошнота или рвота, а также абдоминальная боль. Эти симптомы могут предшествовать появлению респираторных признаков заболевания, а в некоторых случаях выходить на первый план в клинической картине заболевания. Помимо этого, у части больных наблюдаются лабораторные признаки поражения печени (повышение сывороточных трансаминаз). Точный патогенез описанных нарушений продолжает изучаться.
Ключевые слова: COVID-19, SARS-CoV-2, острый инфаркт миокарда, повреждение миокарда, коагулопатия, тромбоз, острый коронарный синдром, диарея, рвота, абдоминальная боль, потеря аппетита.
Keywords: COVID-19, SARS-CoV-2, acute myocardial infarction, myocardial damage, coagulopathy, thrombosis, acute coronary syndrome, diarrhea, vomiting, abdominal pain, loss of appetite.
Ключевые слова: COVID-19, SARS-CoV-2, острый инфаркт миокарда, повреждение миокарда, коагулопатия, тромбоз, острый коронарный синдром, диарея, рвота, абдоминальная боль, потеря аппетита.
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Keywords: COVID-19, SARS-CoV-2, acute myocardial infarction, myocardial damage, coagulopathy, thrombosis, acute coronary syndrome, diarrhea, vomiting, abdominal pain, loss of appetite.
Авторы
И.В. Маев, А.В. Шпектор, Е.Ю. Васильева, В.Н. Манчуров, Д.Н. Андреев
ФГБОУ ВО «Московский государственный медико-стоматологический университет им. А.И. Евдокимова» Минздрава России,
Москва, Россия
Yevdokimov Moscow State University of Medicine and Dentistry, Moscow, Russia
ФГБОУ ВО «Московский государственный медико-стоматологический университет им. А.И. Евдокимова» Минздрава России,
Москва, Россия
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Yevdokimov Moscow State University of Medicine and Dentistry, Moscow, Russia
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