Сроки госпитализации и выполнения эндоваскулярных процедур у пациентов с острым инфарктом миокарда без подъема сегмента ST в реальной клинической практике
Сроки госпитализации и выполнения эндоваскулярных процедур у пациентов с острым инфарктом миокарда без подъема сегмента ST в реальной клинической практике
Рафаели И.Р., Киреева А.Ю., Чернышева И.Е. и др. Сроки госпитализации и выполнения эндоваскулярных процедур у пациентов с острым инфарктом миокарда без подъема сегмента ST в реальной клинической практике. CardioСоматика. 2020; 11 (3): 10–15. DOI: 10.26442/22217185.2020.2020.3.200371
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Аннотация
Цель. Выяснить зависимость тяжести состояния пациентов c острым инфарктом миокарда без подъема сегмента ST при поступлении в стационар по шкале Global Registry of Acute Coronary Events (GRACE) от интервала времени между началом заболевания и госпитализацией («боль–госпитализация»), а также уточнить влияние показателя GRACE на время до эндоваскулярных процедур (ЭВП) – «дверь–баллон» – в реальной клинической практике.
Материал и методы. В исследование включен 421 пациент с острым инфарктом миокарда без подъема сегмента ST. Больные поступали в период с 2000 пo 2017 г. Всем пациентам проводилась коронароангиография с последующей ЭВП. При поступлении в стационар пациенты разделены на 3 группы риска по шкале GRACE. По показателям «боль–госпитализация» и «дверь–баллон» выделили 3 интервала времени: до 6, 6–24 и более 24 ч.
Результаты. При поступлении 73,9% (311) больных имели средний и высокий риск по шкале GRACE. Следует отметить, что больные с высоким риском достоверно чаще (49,6%) госпитализированы в первые 6 ч от начала заболевания, чем в более поздние сроки (6–24 ч – 24,4% и спустя сутки – 26,0%, р<0,05). 2/3 всех больных и 3/4 пациентов с высоким риском имели показатель «боль–госпитализация» до 24 ч. У 51,8% больных общей группы и 65,8% пациентов высокого риска интервал «дверь–баллон» был до 6 ч. В первые 24 ч после госпитализации успешные ЭВП выполнялись у 90,7% пациентов. Летальный исход отмечен в 1 случае. При выписке ни у одного больного не отмечались симптомы стенокардии и сердечной недостаточности.
Заключение. В общей группе по выделенным интервалам времени – «боль–госпитализация» – больные распределялись практически равномерно. При этом на тяжесть состояния исследуемых больных указывает факт, что почти 3/4 из них имели высокий и средний риск по шкале GRACE. Вызывает оптимизм, что в первые 6 ч от начала заболевания достоверно чаще госпитализировались пациенты высокого риска. Почти 2/3 пациентов высокого риска и более чем 1/2 всех больных имели показатель «дверь–баллон» до 6 ч. Немаловажно, что в первые 24 ч успешные ЭВП выполнены у 90,7% больных. Таким образом, полученные нами результаты (низкая смертность, отсутствие клинической картины стенокардии и явлений сердечной недостаточности после ЭВП) свидетельствуют о правильно выбранной тактике ведения и лечения больных с острым инфарктом миокарда без подъема сегмента ST, которая близка к последним мировым рекомендациям, исходит из реальных жизненных обстоятельств и может быть рекомендована для реальной клинической практики.
Ключевые слова: GRACE, острый инфаркт миокарда без подъема сегмента ST, время госпитализации, время реваскуляризации.
Material and methods. The study included 421 NSTEMI patients. Patients were admitted between 2000 and 2017. All patients underwent coronary angiography followed by EVP. Depending on the clinical condition, at admitted to the hospital, patients were divided into risk groups on the GRACE scale. According to the indicators – “pain–hospitalization” and “door–balloon” – 3 time intervals were allocated: ≤6 hours, 6–24 and >24 hours.
Results. At admission, 73.9% (311) patients had an average and high risk on the GRACE scale. Patients with high risk were significantly more often (49.6%) hospitalized during the first 6 hours after onset of the disease than later (p<0.05). 2/3 of all patients and 3/4 of patients with high risk had the time interval of “pain–hospitalization” up to 24 hours. 51.8% patients in the total group and 65.8% among high-risk patients had a “door–balloon” interval up to 6 hours. During first 24 hours after hospitalization EVP was successfully completed on 90.7% of patients. One patient had a fatal outcome. At discharge none of the patients were observed the symptoms of angina pectoris and congestive heart failure.
Conclusion. In the all group, according to the allocated time intervals “pain–hospitalization”, patients were distributed practically equally. The severity of the condition of the studied patients is indicated by the fact that almost 3/4 of them had a high and average risk on the GRACE scale. It is encouraging that in the first 6 hours from the onset of the disease, high-risk patients were significantly more often hospitalized. Almost 2/3 of high-risk patients and more than half of all patients had a “door–balloon” indicator-up to 6 hours. It is important that in the first 24 hours, successful EVP was performed in 90.7% of patients. Thus, our results (low mortality, absence of angina and heart failure after EVP) indicate the correct management and treatment of NSTEMI patients, which is close to the latest world recommendations, comes from real life circumstances and can be recommended for real clinical practice.
Key words: GRACE, NSTEMI, “pain–hospitalization”, “door–balloon”.
Материал и методы. В исследование включен 421 пациент с острым инфарктом миокарда без подъема сегмента ST. Больные поступали в период с 2000 пo 2017 г. Всем пациентам проводилась коронароангиография с последующей ЭВП. При поступлении в стационар пациенты разделены на 3 группы риска по шкале GRACE. По показателям «боль–госпитализация» и «дверь–баллон» выделили 3 интервала времени: до 6, 6–24 и более 24 ч.
Результаты. При поступлении 73,9% (311) больных имели средний и высокий риск по шкале GRACE. Следует отметить, что больные с высоким риском достоверно чаще (49,6%) госпитализированы в первые 6 ч от начала заболевания, чем в более поздние сроки (6–24 ч – 24,4% и спустя сутки – 26,0%, р<0,05). 2/3 всех больных и 3/4 пациентов с высоким риском имели показатель «боль–госпитализация» до 24 ч. У 51,8% больных общей группы и 65,8% пациентов высокого риска интервал «дверь–баллон» был до 6 ч. В первые 24 ч после госпитализации успешные ЭВП выполнялись у 90,7% пациентов. Летальный исход отмечен в 1 случае. При выписке ни у одного больного не отмечались симптомы стенокардии и сердечной недостаточности.
Заключение. В общей группе по выделенным интервалам времени – «боль–госпитализация» – больные распределялись практически равномерно. При этом на тяжесть состояния исследуемых больных указывает факт, что почти 3/4 из них имели высокий и средний риск по шкале GRACE. Вызывает оптимизм, что в первые 6 ч от начала заболевания достоверно чаще госпитализировались пациенты высокого риска. Почти 2/3 пациентов высокого риска и более чем 1/2 всех больных имели показатель «дверь–баллон» до 6 ч. Немаловажно, что в первые 24 ч успешные ЭВП выполнены у 90,7% больных. Таким образом, полученные нами результаты (низкая смертность, отсутствие клинической картины стенокардии и явлений сердечной недостаточности после ЭВП) свидетельствуют о правильно выбранной тактике ведения и лечения больных с острым инфарктом миокарда без подъема сегмента ST, которая близка к последним мировым рекомендациям, исходит из реальных жизненных обстоятельств и может быть рекомендована для реальной клинической практики.
Ключевые слова: GRACE, острый инфаркт миокарда без подъема сегмента ST, время госпитализации, время реваскуляризации.
________________________________________________
Material and methods. The study included 421 NSTEMI patients. Patients were admitted between 2000 and 2017. All patients underwent coronary angiography followed by EVP. Depending on the clinical condition, at admitted to the hospital, patients were divided into risk groups on the GRACE scale. According to the indicators – “pain–hospitalization” and “door–balloon” – 3 time intervals were allocated: ≤6 hours, 6–24 and >24 hours.
Results. At admission, 73.9% (311) patients had an average and high risk on the GRACE scale. Patients with high risk were significantly more often (49.6%) hospitalized during the first 6 hours after onset of the disease than later (p<0.05). 2/3 of all patients and 3/4 of patients with high risk had the time interval of “pain–hospitalization” up to 24 hours. 51.8% patients in the total group and 65.8% among high-risk patients had a “door–balloon” interval up to 6 hours. During first 24 hours after hospitalization EVP was successfully completed on 90.7% of patients. One patient had a fatal outcome. At discharge none of the patients were observed the symptoms of angina pectoris and congestive heart failure.
Conclusion. In the all group, according to the allocated time intervals “pain–hospitalization”, patients were distributed practically equally. The severity of the condition of the studied patients is indicated by the fact that almost 3/4 of them had a high and average risk on the GRACE scale. It is encouraging that in the first 6 hours from the onset of the disease, high-risk patients were significantly more often hospitalized. Almost 2/3 of high-risk patients and more than half of all patients had a “door–balloon” indicator-up to 6 hours. It is important that in the first 24 hours, successful EVP was performed in 90.7% of patients. Thus, our results (low mortality, absence of angina and heart failure after EVP) indicate the correct management and treatment of NSTEMI patients, which is close to the latest world recommendations, comes from real life circumstances and can be recommended for real clinical practice.
Key words: GRACE, NSTEMI, “pain–hospitalization”, “door–balloon”.
Список литературы
1. Мировая статистика здравоохранения, 2017 г. Информационный бюллетень ВОЗ. 2018.
[World Health Statistics, 2017 year. Newsletter of the WHO. 2018 (in Russian).]
2. Roffi М, Patrono С, Collet JP et al. 2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. Eur Heart J 2016; 37 (3): 267–315. DOI: 10.1093/eurheartj/ehv320
3. Brandao RM, Samesima N, Pastore CA et al. ST-segment abnormalities are associated with long-term prognosis in non-ST-segment elevation acute coronary syndromes: The ERICO-ECG study. J Electrocardiol 2016; 49 (3): 411–6. DOI: 10.1016/j.jelectrocard.2016.01.005
4. Vagnarelli F, Taglieri N, Ortolani P. Long-Term Outcomes and Causes of Death After Acute Coronary Syndrome in Patients in the Bologna, Italy, Area. Am J Cardiol 2015; 115 (2): 171–7. DOI: 10.1016/j.amjcard.2014.10.019
5. Сыркин А.Л., Нoвикoва Н.А., Терехин С.А. Oстрый кoрoнарный синдрoм. М.: Мед. инфoрмационное агентство, 2010.
[Syrkin A.L., Novikova N.A., Terekhin S.A. Ostryi koronarnyi sindrom. Moscow: Med. news agency, 2010 (in Russian).]
6. Thiele H, Rach J, Klein N et al. Optimal timing of invasive angiography in stable non-ST-elevation myocardial infarction: the Leipzig immediate versus early and late Percutaneous coronary intervention triаl in NSTEMI (LIPSIA-NSTEMI trial). Eur Heart J 2012; 33 (16): 2035–43. DOI: 10.1093/eurheartj/ehr418
7. Morgado G, Pereira H, Caldeira D. Adopting an early invasive strategy for non-ST-elevation myocardial infarction: Analysis of the Portuguese Registry on Acute Coronary Syndromes. Rev Port Cardiol 2018; 37 (1): 53–61. DOI: 10.1016/j.repc.2017.06.008
8. Neumann F, Sousa-Uva M, Ahlsson A et al. 2018 ESC/EACTS Guidelines on myocardial revascularization. Eur Heart J 2019; 40 (2): 87–165. DOI: 10.1093/eurheartj/ehy394
9. Heitner JF, Senthilkumar А, Harrison JK et al. Identifying the Infarct-Related Artery in Patients With Non–ST-Segment–Elevation Myocardial Infarction. Circulation 2019; 12 (5): e007305. DOI: 10.1161/CIRCINTERVENTIONS.118.007305
10. Hof AWJ, Badings E. NSTEMI treatment: should we always follow the guidelines? Neth Heart J 2019; 27: 171–5. DOI: 10.1007/s12471-019-1244-3
11. Tang EW, Wong CK, Herbison P. Global Registry of Acute Coronary Events (GRACE) hospital discharge risk score accurately predicts long-term mortality post acute coronary syndrome. Am Heart
J 2007; 153 (1): 29–35. DOI: 10.1016/j.ahj.2006.10.004
12. Milasinovic D, Milosevic А, Vasiljevic Z. Three-Year Impact of Immediate Invasive Strategy in Patients with Non-ST-Segment Elevation Myocardial Infarction (from the RIDDLE-NSTEMI Study). Am J Card 2018; 122 (1): 54с60. DOI: 10.1016/j.amjcard.2018.03.006
13. Fu R, Song C, Yang J. CAMI-NSTEMI Score – China Acute Myocardial Infarction Registry-Derived Novel Tool to Predict In-Hospital Death in Non-ST Segment Elevation Myocardial Infarction Patients. Circulation 2018; 82 (7): 1884–91. DOI: 10.1253/circj.CJ-17-1078
14. Рафаели И.Р., Киреева А.Ю., Семитко С.П. и др. Зависимость тяжести клиническoгo сoстoяния пациентoв с острым инфарктoм миoкарда без пoдъема сегмента ST от степени пoражения кoрoнарных артерий пo шкале SYNTAX при поступлении в стационар. Сonsilium Medicum. 2020; 22 (1): 61–6. DOI: 10.26442/ 20751753.2020.1.200004
[Rafaeli I.R., Kireeva A.Iu., Semitko S.P. et al. The correlation оf the severity оf the clinical condition in patients with acute myocardial infarction without ST-segment elevation and the degree оf cоrоnary artery lesion by SYNTAX scоre. Consilium Medicum. 2020; 22 (1): 61–6. DOI: 10.26442/20751753.2020.1.200004 (in Russian).]
15. Беленков Ю.Н. Дисфункция левого желудочка у больных ИБС: современные методы диагностики, медикаментозной и немедикаментозной коррекции. Рус. мед. журн. 2000; 8 (17): 685–93.
[Belenkov Yu.N. Disfunkcziia levogo zheludochka u bol'ny'x IBS: sovremenny'e metody' diagnostiki, medikamentoznoi i nemedikamentoznoi korrektsii. Rus. med. zhurn. 2000; 8 (17): 685–93 (in Russian).]
16. Stanton A. Glantz. Primer Biostatistics. New York: McGraw-Hill, 2002.
17. Kastrati A, Neumann FJ, Schulz S et al. Abciximab and heparin versus bivalirudin for non-ST-elevation myocardial infarction. N Engl J Med 2011; 365 (21): 1980–9. DOI: 10.1056/NEJMoa1109596
18. Yang Q, Wang Y, Liu J et al. Percutaneous Coronary Intervention Among Patients With non-ST-segment Elevation Myocardial Infarction and Unstable Angina: Findings From the Improving Care for Cardiovascular Disease in China Project. Сirc 2016; 134 (1): A17467.
19. Milosevic А, Vasiljevic-Pokrajcic Z, Milasinovic D et al. Immediate Versus Delayed Invasive Intervention for Non-STEMI Patients. JACC Cardiovasc Interv 2016; 9 (6): 541–9. DOI: 10.1016/j.jcin.2015.11.018
20. Lemesle G, Laine M, Pankert M et al. Optimal Timing of Intervention in NSTE-ACS Without Pre-Treatment. J Am Coll Cardiol 2020; 13 (8): 907–17. DOI: 10.1016/j.jcin.2020.01.231
21. Kofoed KF, Kelbak H, Hansen PR et al. Early Versus Standard Care Invasive Examination and Treatment of Patients with Non-ST-Segment Elevation Acute Coronary Syndrome. Circulation 2018; 138: 2741–50. DOI: 10.1161/CIRCULATIONAHA.118.037152
22. Deharo P, Ducrocq G, Bode C. Timing of Angiography and Outcomes in High-Risk Patients With Non-ST-Segment-Elevation Myocardial Infarction Managed Invasively: Insights From the TAO Trial. Circulation 2017; 136 (20): 189–907. DOI: 10.1161/CIRCULATIONAHA.117.029779
23. Iantorno М, Shlofmitz Е, Rogers Т et al. Should Non-ST-Elevation Myocardial Infarction be Treated like ST-Elevation Myocardial Infarction With Shorter Door-to-Balloon Time? Am
J Cardiol 2020; 125 (2): 165–8. DOI: 10.1016/j.amjcard.2019.10.012
24. Bhatia S, Arora S, Deshmukh A et al. Non-ST-Segment – Elevation Myocardial Infarction Among Patients With Chronic Kidney Disease: A Propensity Score – Matched Comparison of Percutaneous Coronary Intervention Versus Conservative Management. J Am Heart Assoc 2018; 7 (6): e007920. DOI: 10.1161/JAHA.117.007920.
2. Roffi М, Patrono С, Collet JP et al. 2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. Eur Heart J 2016; 37 (3): 267–315. DOI: 10.1093/eurheartj/ehv320
3. Brandao RM, Samesima N, Pastore CA et al. ST-segment abnormalities are associated with long-term prognosis in non-ST-segment elevation acute coronary syndromes: The ERICO-ECG study. J Electrocardiol 2016; 49 (3): 411–6. DOI: 10.1016/j.jelectrocard.2016.01.005
4. Vagnarelli F, Taglieri N, Ortolani P. Long-Term Outcomes and Causes of Death After Acute Coronary Syndrome in Patients in the Bologna, Italy, Area. Am J Cardiol 2015; 115 (2): 171–7. DOI: 10.1016/j.amjcard.2014.10.019
5. Syrkin A.L., Novikova N.A., Terekhin S.A. Ostryi koronarnyi sindrom. Moscow: Med. news agency, 2010 (in Russian).
6. Thiele H, Rach J, Klein N et al. Optimal timing of invasive angiography in stable non-ST-elevation myocardial infarction: the Leipzig immediate versus early and late Percutaneous coronary intervention triаl in NSTEMI (LIPSIA-NSTEMI trial). Eur Heart J 2012; 33 (16): 2035–43. DOI: 10.1093/eurheartj/ehr418
7. Morgado G, Pereira H, Caldeira D. Adopting an early invasive strategy for non-ST-elevation myocardial infarction: Analysis of the Portuguese Registry on Acute Coronary Syndromes. Rev Port Cardiol 2018; 37 (1): 53–61. DOI: 10.1016/j.repc.2017.06.008
8. Neumann F, Sousa-Uva M, Ahlsson A et al. 2018 ESC/EACTS Guidelines on myocardial revascularization. Eur Heart J 2019; 40 (2): 87–165. DOI: 10.1093/eurheartj/ehy394
9. Heitner JF, Senthilkumar А, Harrison JK et al. Identifying the Infarct-Related Artery in Patients With Non–ST-Segment–Elevation Myocardial Infarction. Circulation 2019; 12 (5): e007305. DOI: 10.1161/CIRCINTERVENTIONS.118.007305
10. Hof AWJ, Badings E. NSTEMI treatment: should we always follow the guidelines? Neth Heart J 2019; 27: 171–5. DOI: 10.1007/s12471-019-1244-3
11. Tang EW, Wong CK, Herbison P. Global Registry of Acute Coronary Events (GRACE) hospital discharge risk score accurately predicts long-term mortality post acute coronary syndrome. Am Heart
J 2007; 153 (1): 29–35. DOI: 10.1016/j.ahj.2006.10.004
12. Milasinovic D, Milosevic А, Vasiljevic Z. Three-Year Impact of Immediate Invasive Strategy in Patients with Non-ST-Segment Elevation Myocardial Infarction (from the RIDDLE-NSTEMI Study). Am J Card 2018; 122 (1): 54с60. DOI: 10.1016/j.amjcard.2018.03.006
13. Fu R, Song C, Yang J. CAMI-NSTEMI Score – China Acute Myocardial Infarction Registry-Derived Novel Tool to Predict In-Hospital Death in Non-ST Segment Elevation Myocardial Infarction Patients. Circulation 2018; 82 (7): 1884–91. DOI: 10.1253/circj.CJ-17-1078
14. Rafaeli I.R., Kireeva A.Iu., Semitko S.P. et al. The correlation оf the severity оf the clinical condition in patients with acute myocardial infarction without ST-segment elevation and the degree оf cоrоnary artery lesion by SYNTAX scоre. Consilium Medicum. 2020; 22 (1): 61–6. DOI: 10.26442/20751753.2020.1.200004 (in Russian).
15. Belenkov Yu.N. Disfunkcziia levogo zheludochka u bol'ny'x IBS: sovremenny'e metody' diagnostiki, medikamentoznoi i nemedikamentoznoi korrektsii. Rus. med. zhurn. 2000; 8 (17): 685–93 (in Russian).
16. Stanton A. Glantz. Primer Biostatistics. New York: McGraw-Hill, 2002.
17. Kastrati A, Neumann FJ, Schulz S et al. Abciximab and heparin versus bivalirudin for non-ST-elevation myocardial infarction. N Engl J Med 2011; 365 (21): 1980–9. DOI: 10.1056/NEJMoa1109596
18. Yang Q, Wang Y, Liu J et al. Percutaneous Coronary Intervention Among Patients With non-ST-segment Elevation Myocardial Infarction and Unstable Angina: Findings From the Improving Care for Cardiovascular Disease in China Project. Сirc 2016; 134 (1): A17467.
19. Milosevic А, Vasiljevic-Pokrajcic Z, Milasinovic D et al. Immediate Versus Delayed Invasive Intervention for Non-STEMI Patients. JACC Cardiovasc Interv 2016; 9 (6): 541–9. DOI: 10.1016/j.jcin.2015.11.018
20. Lemesle G, Laine M, Pankert M et al. Optimal Timing of Intervention in NSTE-ACS Without Pre-Treatment. J Am Coll Cardiol 2020; 13 (8): 907–17. DOI: 10.1016/j.jcin.2020.01.231
21. Kofoed KF, Kelbak H, Hansen PR et al. Early Versus Standard Care Invasive Examination and Treatment of Patients with Non-ST-Segment Elevation Acute Coronary Syndrome. Circulation 2018; 138: 2741–50. DOI: 10.1161/CIRCULATIONAHA.118.037152
22. Deharo P, Ducrocq G, Bode C. Timing of Angiography and Outcomes in High-Risk Patients With Non-ST-Segment-Elevation Myocardial Infarction Managed Invasively: Insights From the TAO Trial. Circulation 2017; 136 (20): 189–907. DOI: 10.1161/CIRCULATIONAHA.117.029779
23. Iantorno М, Shlofmitz Е, Rogers Т et al. Should Non-ST-Elevation Myocardial Infarction be Treated like ST-Elevation Myocardial Infarction With Shorter Door-to-Balloon Time? Am
J Cardiol 2020; 125 (2): 165–8. DOI: 10.1016/j.amjcard.2019.10.012
24. Bhatia S, Arora S, Deshmukh A et al. Non-ST-Segment – Elevation Myocardial Infarction Among Patients With Chronic Kidney Disease: A Propensity Score – Matched Comparison of Percutaneous Coronary Intervention Versus Conservative Management. J Am Heart Assoc 2018; 7 (6): e007920. DOI: 10.1161/JAHA.117.007920.
[World Health Statistics, 2017 year. Newsletter of the WHO. 2018 (in Russian).]
2. Roffi М, Patrono С, Collet JP et al. 2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. Eur Heart J 2016; 37 (3): 267–315. DOI: 10.1093/eurheartj/ehv320
3. Brandao RM, Samesima N, Pastore CA et al. ST-segment abnormalities are associated with long-term prognosis in non-ST-segment elevation acute coronary syndromes: The ERICO-ECG study. J Electrocardiol 2016; 49 (3): 411–6. DOI: 10.1016/j.jelectrocard.2016.01.005
4. Vagnarelli F, Taglieri N, Ortolani P. Long-Term Outcomes and Causes of Death After Acute Coronary Syndrome in Patients in the Bologna, Italy, Area. Am J Cardiol 2015; 115 (2): 171–7. DOI: 10.1016/j.amjcard.2014.10.019
5. Сыркин А.Л., Нoвикoва Н.А., Терехин С.А. Oстрый кoрoнарный синдрoм. М.: Мед. инфoрмационное агентство, 2010.
[Syrkin A.L., Novikova N.A., Terekhin S.A. Ostryi koronarnyi sindrom. Moscow: Med. news agency, 2010 (in Russian).]
6. Thiele H, Rach J, Klein N et al. Optimal timing of invasive angiography in stable non-ST-elevation myocardial infarction: the Leipzig immediate versus early and late Percutaneous coronary intervention triаl in NSTEMI (LIPSIA-NSTEMI trial). Eur Heart J 2012; 33 (16): 2035–43. DOI: 10.1093/eurheartj/ehr418
7. Morgado G, Pereira H, Caldeira D. Adopting an early invasive strategy for non-ST-elevation myocardial infarction: Analysis of the Portuguese Registry on Acute Coronary Syndromes. Rev Port Cardiol 2018; 37 (1): 53–61. DOI: 10.1016/j.repc.2017.06.008
8. Neumann F, Sousa-Uva M, Ahlsson A et al. 2018 ESC/EACTS Guidelines on myocardial revascularization. Eur Heart J 2019; 40 (2): 87–165. DOI: 10.1093/eurheartj/ehy394
9. Heitner JF, Senthilkumar А, Harrison JK et al. Identifying the Infarct-Related Artery in Patients With Non–ST-Segment–Elevation Myocardial Infarction. Circulation 2019; 12 (5): e007305. DOI: 10.1161/CIRCINTERVENTIONS.118.007305
10. Hof AWJ, Badings E. NSTEMI treatment: should we always follow the guidelines? Neth Heart J 2019; 27: 171–5. DOI: 10.1007/s12471-019-1244-3
11. Tang EW, Wong CK, Herbison P. Global Registry of Acute Coronary Events (GRACE) hospital discharge risk score accurately predicts long-term mortality post acute coronary syndrome. Am Heart
J 2007; 153 (1): 29–35. DOI: 10.1016/j.ahj.2006.10.004
12. Milasinovic D, Milosevic А, Vasiljevic Z. Three-Year Impact of Immediate Invasive Strategy in Patients with Non-ST-Segment Elevation Myocardial Infarction (from the RIDDLE-NSTEMI Study). Am J Card 2018; 122 (1): 54с60. DOI: 10.1016/j.amjcard.2018.03.006
13. Fu R, Song C, Yang J. CAMI-NSTEMI Score – China Acute Myocardial Infarction Registry-Derived Novel Tool to Predict In-Hospital Death in Non-ST Segment Elevation Myocardial Infarction Patients. Circulation 2018; 82 (7): 1884–91. DOI: 10.1253/circj.CJ-17-1078
14. Рафаели И.Р., Киреева А.Ю., Семитко С.П. и др. Зависимость тяжести клиническoгo сoстoяния пациентoв с острым инфарктoм миoкарда без пoдъема сегмента ST от степени пoражения кoрoнарных артерий пo шкале SYNTAX при поступлении в стационар. Сonsilium Medicum. 2020; 22 (1): 61–6. DOI: 10.26442/ 20751753.2020.1.200004
[Rafaeli I.R., Kireeva A.Iu., Semitko S.P. et al. The correlation оf the severity оf the clinical condition in patients with acute myocardial infarction without ST-segment elevation and the degree оf cоrоnary artery lesion by SYNTAX scоre. Consilium Medicum. 2020; 22 (1): 61–6. DOI: 10.26442/20751753.2020.1.200004 (in Russian).]
15. Беленков Ю.Н. Дисфункция левого желудочка у больных ИБС: современные методы диагностики, медикаментозной и немедикаментозной коррекции. Рус. мед. журн. 2000; 8 (17): 685–93.
[Belenkov Yu.N. Disfunkcziia levogo zheludochka u bol'ny'x IBS: sovremenny'e metody' diagnostiki, medikamentoznoi i nemedikamentoznoi korrektsii. Rus. med. zhurn. 2000; 8 (17): 685–93 (in Russian).]
16. Stanton A. Glantz. Primer Biostatistics. New York: McGraw-Hill, 2002.
17. Kastrati A, Neumann FJ, Schulz S et al. Abciximab and heparin versus bivalirudin for non-ST-elevation myocardial infarction. N Engl J Med 2011; 365 (21): 1980–9. DOI: 10.1056/NEJMoa1109596
18. Yang Q, Wang Y, Liu J et al. Percutaneous Coronary Intervention Among Patients With non-ST-segment Elevation Myocardial Infarction and Unstable Angina: Findings From the Improving Care for Cardiovascular Disease in China Project. Сirc 2016; 134 (1): A17467.
19. Milosevic А, Vasiljevic-Pokrajcic Z, Milasinovic D et al. Immediate Versus Delayed Invasive Intervention for Non-STEMI Patients. JACC Cardiovasc Interv 2016; 9 (6): 541–9. DOI: 10.1016/j.jcin.2015.11.018
20. Lemesle G, Laine M, Pankert M et al. Optimal Timing of Intervention in NSTE-ACS Without Pre-Treatment. J Am Coll Cardiol 2020; 13 (8): 907–17. DOI: 10.1016/j.jcin.2020.01.231
21. Kofoed KF, Kelbak H, Hansen PR et al. Early Versus Standard Care Invasive Examination and Treatment of Patients with Non-ST-Segment Elevation Acute Coronary Syndrome. Circulation 2018; 138: 2741–50. DOI: 10.1161/CIRCULATIONAHA.118.037152
22. Deharo P, Ducrocq G, Bode C. Timing of Angiography and Outcomes in High-Risk Patients With Non-ST-Segment-Elevation Myocardial Infarction Managed Invasively: Insights From the TAO Trial. Circulation 2017; 136 (20): 189–907. DOI: 10.1161/CIRCULATIONAHA.117.029779
23. Iantorno М, Shlofmitz Е, Rogers Т et al. Should Non-ST-Elevation Myocardial Infarction be Treated like ST-Elevation Myocardial Infarction With Shorter Door-to-Balloon Time? Am
J Cardiol 2020; 125 (2): 165–8. DOI: 10.1016/j.amjcard.2019.10.012
24. Bhatia S, Arora S, Deshmukh A et al. Non-ST-Segment – Elevation Myocardial Infarction Among Patients With Chronic Kidney Disease: A Propensity Score – Matched Comparison of Percutaneous Coronary Intervention Versus Conservative Management. J Am Heart Assoc 2018; 7 (6): e007920. DOI: 10.1161/JAHA.117.007920.
________________________________________________
2. Roffi М, Patrono С, Collet JP et al. 2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. Eur Heart J 2016; 37 (3): 267–315. DOI: 10.1093/eurheartj/ehv320
3. Brandao RM, Samesima N, Pastore CA et al. ST-segment abnormalities are associated with long-term prognosis in non-ST-segment elevation acute coronary syndromes: The ERICO-ECG study. J Electrocardiol 2016; 49 (3): 411–6. DOI: 10.1016/j.jelectrocard.2016.01.005
4. Vagnarelli F, Taglieri N, Ortolani P. Long-Term Outcomes and Causes of Death After Acute Coronary Syndrome in Patients in the Bologna, Italy, Area. Am J Cardiol 2015; 115 (2): 171–7. DOI: 10.1016/j.amjcard.2014.10.019
5. Syrkin A.L., Novikova N.A., Terekhin S.A. Ostryi koronarnyi sindrom. Moscow: Med. news agency, 2010 (in Russian).
6. Thiele H, Rach J, Klein N et al. Optimal timing of invasive angiography in stable non-ST-elevation myocardial infarction: the Leipzig immediate versus early and late Percutaneous coronary intervention triаl in NSTEMI (LIPSIA-NSTEMI trial). Eur Heart J 2012; 33 (16): 2035–43. DOI: 10.1093/eurheartj/ehr418
7. Morgado G, Pereira H, Caldeira D. Adopting an early invasive strategy for non-ST-elevation myocardial infarction: Analysis of the Portuguese Registry on Acute Coronary Syndromes. Rev Port Cardiol 2018; 37 (1): 53–61. DOI: 10.1016/j.repc.2017.06.008
8. Neumann F, Sousa-Uva M, Ahlsson A et al. 2018 ESC/EACTS Guidelines on myocardial revascularization. Eur Heart J 2019; 40 (2): 87–165. DOI: 10.1093/eurheartj/ehy394
9. Heitner JF, Senthilkumar А, Harrison JK et al. Identifying the Infarct-Related Artery in Patients With Non–ST-Segment–Elevation Myocardial Infarction. Circulation 2019; 12 (5): e007305. DOI: 10.1161/CIRCINTERVENTIONS.118.007305
10. Hof AWJ, Badings E. NSTEMI treatment: should we always follow the guidelines? Neth Heart J 2019; 27: 171–5. DOI: 10.1007/s12471-019-1244-3
11. Tang EW, Wong CK, Herbison P. Global Registry of Acute Coronary Events (GRACE) hospital discharge risk score accurately predicts long-term mortality post acute coronary syndrome. Am Heart
J 2007; 153 (1): 29–35. DOI: 10.1016/j.ahj.2006.10.004
12. Milasinovic D, Milosevic А, Vasiljevic Z. Three-Year Impact of Immediate Invasive Strategy in Patients with Non-ST-Segment Elevation Myocardial Infarction (from the RIDDLE-NSTEMI Study). Am J Card 2018; 122 (1): 54с60. DOI: 10.1016/j.amjcard.2018.03.006
13. Fu R, Song C, Yang J. CAMI-NSTEMI Score – China Acute Myocardial Infarction Registry-Derived Novel Tool to Predict In-Hospital Death in Non-ST Segment Elevation Myocardial Infarction Patients. Circulation 2018; 82 (7): 1884–91. DOI: 10.1253/circj.CJ-17-1078
14. Rafaeli I.R., Kireeva A.Iu., Semitko S.P. et al. The correlation оf the severity оf the clinical condition in patients with acute myocardial infarction without ST-segment elevation and the degree оf cоrоnary artery lesion by SYNTAX scоre. Consilium Medicum. 2020; 22 (1): 61–6. DOI: 10.26442/20751753.2020.1.200004 (in Russian).
15. Belenkov Yu.N. Disfunkcziia levogo zheludochka u bol'ny'x IBS: sovremenny'e metody' diagnostiki, medikamentoznoi i nemedikamentoznoi korrektsii. Rus. med. zhurn. 2000; 8 (17): 685–93 (in Russian).
16. Stanton A. Glantz. Primer Biostatistics. New York: McGraw-Hill, 2002.
17. Kastrati A, Neumann FJ, Schulz S et al. Abciximab and heparin versus bivalirudin for non-ST-elevation myocardial infarction. N Engl J Med 2011; 365 (21): 1980–9. DOI: 10.1056/NEJMoa1109596
18. Yang Q, Wang Y, Liu J et al. Percutaneous Coronary Intervention Among Patients With non-ST-segment Elevation Myocardial Infarction and Unstable Angina: Findings From the Improving Care for Cardiovascular Disease in China Project. Сirc 2016; 134 (1): A17467.
19. Milosevic А, Vasiljevic-Pokrajcic Z, Milasinovic D et al. Immediate Versus Delayed Invasive Intervention for Non-STEMI Patients. JACC Cardiovasc Interv 2016; 9 (6): 541–9. DOI: 10.1016/j.jcin.2015.11.018
20. Lemesle G, Laine M, Pankert M et al. Optimal Timing of Intervention in NSTE-ACS Without Pre-Treatment. J Am Coll Cardiol 2020; 13 (8): 907–17. DOI: 10.1016/j.jcin.2020.01.231
21. Kofoed KF, Kelbak H, Hansen PR et al. Early Versus Standard Care Invasive Examination and Treatment of Patients with Non-ST-Segment Elevation Acute Coronary Syndrome. Circulation 2018; 138: 2741–50. DOI: 10.1161/CIRCULATIONAHA.118.037152
22. Deharo P, Ducrocq G, Bode C. Timing of Angiography and Outcomes in High-Risk Patients With Non-ST-Segment-Elevation Myocardial Infarction Managed Invasively: Insights From the TAO Trial. Circulation 2017; 136 (20): 189–907. DOI: 10.1161/CIRCULATIONAHA.117.029779
23. Iantorno М, Shlofmitz Е, Rogers Т et al. Should Non-ST-Elevation Myocardial Infarction be Treated like ST-Elevation Myocardial Infarction With Shorter Door-to-Balloon Time? Am
J Cardiol 2020; 125 (2): 165–8. DOI: 10.1016/j.amjcard.2019.10.012
24. Bhatia S, Arora S, Deshmukh A et al. Non-ST-Segment – Elevation Myocardial Infarction Among Patients With Chronic Kidney Disease: A Propensity Score – Matched Comparison of Percutaneous Coronary Intervention Versus Conservative Management. J Am Heart Assoc 2018; 7 (6): e007920. DOI: 10.1161/JAHA.117.007920.
Авторы
И.Р. Рафаели*, А.Ю. Киреева, И.Е. Чернышева, И.Ю. Костянов, Н.В. Церетели, А.В. Азаров, А.В. Степанов, С.П. Семитко
ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский Университет), Москва, Россия
*rafaeli50@yandex.ru
Scientific and Practical Center of interventional Cardioangiology, Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia
*rafaeli50@yandex.ru
ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский Университет), Москва, Россия
*rafaeli50@yandex.ru
________________________________________________
Scientific and Practical Center of interventional Cardioangiology, Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia
*rafaeli50@yandex.ru
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