Фенотип современного пациента с приобретёнными пороками клапанов сердца: обзор литературы

1. Кардиология. Национальное руководство. 2-е изд., перераб. и доп. / под ред. Е.В. Шляхто. Москва: ГЭОТАР-Медиа, 2019.
2. Santangelo G., Bursi F., Faggiano A., et al. The Global Burden of Valvular Heart Disease: From Clinical Epidemiology to Management // J Clin Med. 2023. Vol. 12, N 6. P. 2178.
doi: 10.3390/jcm12062178
3. Sharma T., Krishnan A.M., Lahoud R., et al. National trends in TAVR and SAVR for patients with severe isolated aortic stenosis // J Am Coll Cardiol. 2022. Vol. 80, N 21.
P. 2054–2056. doi: 10.1016/j.jacc.2022.08.787
4. Голухова Е.З. Отчет о научной и лечебной работе Национального медицинского исследовательского центра сердечно-сосудистой хирургии им. А.Н. Бакулева Минздрава России за 2021 год и перспективы развития // Бюллетень НЦССХ им. А.Н. Бакулева РАМН. Сердечно-сосудистые заболевания. 2022. Т. 23, № S. С. 5–111.
doi: 10.24022/1810-0694-2022-23S
5. van der Heijden C.A.J., Verheule S., Olsthoorn J., et al. Postoperative atrial fibrillation and atrial epicardial fat: Is there a link? // Int J Cardiol Heart Vasc. 2022. N 39. P. 100976. 
doi: 10.1016/j.ijcha.2022.100976
6. Деева Н.С., Шабалдин А.В., Антонова Л.В. Роль нарушений обмена кальция в индукции иммунной гиперчувствительности при сердечно-сосудистых заболеваниях // Бюллетень сибирской медицины. 2021. Т. 20, № 3. С. 141–151. doi: 10.20538/1682-0363-2021-3-141-151
7. Koenen M., Hill M.A., Cohen P., Sowers J.R. Obesity, Adipose Tissue and Vascular Dysfunction // Circ Res. 2021. Vol. 128, N 7. P. 951–968. doi: 10.1161/CIRCRESAHA.121.318093
8. Iung B., Delgado V., Rosenhek R., et al. Contemporary presentation and management of valvular heart disease the EURObservational research programme valvular heart disease II survey. Circulation. 2019. Vol. 140, N 14. P. 1156–1169. doi: 10.1161/CIRCULATIONAHA.119.041080
9. Go A.S., Mozaffarian D., Roger V.L., et al. Heart disease and stroke statistics — 2014 update: a report from the American Heart Association // Circulation. 2014. Vol. 129, N 3.
P. e28–e292. doi: 10.1161/01.cir.0000441139.02102.80
10. Aluru J.S., Barsouk A., Saginala K., et al. Valvular heart disease epidemiology // Med Sci (Basel). 2022. Vol. 10, N 2. P. 32. doi: 10.3390/medsci10020032
11. Кардиология. Национальное руководство 2-е изд., перераб. и доп. / под ред. Е.В. Шляхто. Москва: ГЭОТАР-Медиа, 2015.
12. Джорджикия Р.К., Харитонов Г.И. Современные аспекты диагностики и хирургического лечения приобретенных пороков сердца // Практическая медицина. 2003. № 2. С. 25–26.
13. Рубаненко А.О., Дьячков В.А., Щукин Ю.В., и др. Приобретенные пороки сердца: клиническая картина, диагностика // ­Кардиология: новости, мнения, обучение. 2019. Т. 7, № 3. C. 26–36. doi: 10.24411/2309-1908-2019-13003
14. Приказ Минздрава Российской Федерации № 283 от 30 ноября 1993 г. «О совершенствовании службы функциональной диагностики в учреждениях здравоохранения Российской Федерации». Режим доступа: https://normativ.kontur.ru/document?moduleId=1&documentId=71530. Дата обращения: 10.11.2023.
15. Тюрин И.Е. Лучевая диагностика в Российской Федерации в 2016 г. // Вестник рентгенологии и радиологии. 2017. Т. 98, № 4. С. 219–226.
doi: 10.20862/0042-4676-2017-98-4-219-226
16. Сачек О.И., Берестень Н.Ф., Толмачев Д.А., Осков Ю.И. Обеспеченность и укомплектованность амбулаторно-поликлинических отделений врачами функциональной диагностики в Российской Федерации, Федеральных округах и пилотных субъектах в 2012–2016 годах // Медицинский алфавит. 2018. Т. 1, № 14. С. 7–12.
17. Beckmann A., Funkat A.K., Lewandowski J., et al. German heart surgery report 2015: the annual updated registry of the German society for thoracic and cardiovascular surgery // The Thorac Cardiovasc Surg. 2016. Vol. 64, N 6. P. 462–474. doi: 10.1055/s-0036-1592124
18. Хубулава Г.Г., Гуляев Н.И., Кравчук В.Н., и др. Место дегенеративного стеноза клапана аорты в структуре приобретенных пороков сердца // Грудная и сердечно-сосудистая хирургия. 2018. Т. 60, № 1. С. 28–35. doi: 10.24022/0236-2791-2018-60-1-28-35
19. Семенов В.Ю., Самородская И.В., Ларина В.Н., Андреев Е.М. Показатели смертности от приобретенных пороков сердца за 15-летний период в Российской Федерации и Соединенных Штатах Америки и анализ факторов, влияющих на их формирование // Креативная кардиология. 2017. Т. 11, № 3. С. 235–246.
doi: 10.24022/1997-3187-2017-11-2-235-246
20. Yadgir S., Johnson C.O., Aboyans V., et al. Global, regional, and national burden of calcific aortic valve and degenerative mitral valve diseases, 1990–2017 // Circulation. 2020.
Vol. 141, N 21. P. 1670–1680. doi: 10.1161/CIRCULATIONAHA.119.043391
21. Shariff M., Kumar A., Hirji S.A., et al. Ten Years Mortality Trends of Tricuspid Regurgitation in the United States, 2008 to 2018 // Am J Cardiol. 2021. N 140. P. 156–157.
doi: 10.1016/j.amjcard.2020.11.024
22. Pierard S., Seldrum S., de Meester C., et al. Incidence, determinants and prognostic impact of operative refusal or denial in octogenarians with severe aortic stenosis // Ann Thorac Surg. 2011. Vol. 91, N 4. P. 1107–1112. doi: 10.1016/j.athoracsur.2010.12.052
23. Huang X., Dhruva S.S., Yuan X., et al. Characteristics, interventions and outcomes of patients with valvular heart disease hospitalised in China: a cross-sectional study // BMJ Open. 2021. Vol. 11, N 11. P. e052946. doi: 10.1136/bmjopen-2021-052946
24. Izumi C., Matsuyama R., Yamabe K., et al. In-Hospital Outcomes of Heart Failure Patients with Valvular Heart Disease: Insights from Real-World Claims Data // Clinicoecon Outcomes Res. 2023. N 15. P. 349–360. doi: 10.2147/CEOR.S405079
25. Smith P.K., Puskas J.D., Ascheim D.D., et al. Surgical treatment of moderate ischemic mitral regurgitation // N Engl J Med. 2014. Vol. 371, N 23. P. 2178–2188.
doi: 10.1056/NEJMoa1410490
26. Virk S.A., Sriravindrarajah A., Dunn D., et al. A meta-analysis of mitral valve repair versus replacement for ischemic mitral regurgitation // Ann Cardiothorac Surg. 2015. Vol. 4, N 5.
P. 400–410. doi: 10.3978/j.issn.2225-319X.2015.09.06
27. Sabate M., Canovas S., Garcia E., et al. In-hospital and mid-term predictors of mortality after transcatheter aortic valve implantation: data from the TAVI National Registry 2010–2011 // Rev Esp Cardiol (Engl Ed). 2013. Vol. 66, N 12. P. 949–958. doi: 10.1016/j.rec.2013.07.003
28. Rodés-Cabau J., Dumont E., De LaRochellière R., et al. Feasibility and initial results of percutaneous aortic valve implantation including selection of the transfemoral or transapical approach in patients with severe aortic stenosis // Am J Cardiol. 2008. Vol. 102, N 9. P. 1240–1246. doi: 10.1016/j.amjcard.2008.06.061
29. Dreyfus J., Audureau E., Bohbot Y., et al. TRI-SCORE: a new risk score for in-hospital mortality prediction after isolated tricuspid valve surgery // Eur Heart J. 2022. Vol. 43, N 7.
P. 654–662. doi: 10.1093/eurheartj/ehab679
30. Coffey S., Harper A.R., Cairns B.J., et al. Clinical information has low sensitivity for postmortem diagnosis of heart valve disease // Heart. 2017. Vol. 103, N 13. P. 1031–1035.
doi: 10.1136/heartjnl-2016-310718
31. Marangou J., Beaton A., Aliku T.O., et al. Echocardiography in Indigenous Populations and Resource Poor Settings // Heart Lung Circ. 2019. Vol. 28, N 9. P. 1427–1435.
doi: 10.1016/j.hlc.2019.05.176
32. Kang D., Bash D., Chetcuti S., et al. Mortality predictors in patients referred for but not undergoing transcatheter aortic valve replacement // Am J Cardiol. 2015. Vol. 116, N 6.
P. 919–924. doi: 10.1016/j.amjcard.2015.06.014
33. Iung B., Cachier A., Baron G., et al. Decision-making in elderly patients with severe aortic stenosis: why are so many denied surgery? // Eur Heart J. 2005. Vol. 26, N 24.
P. 2714–2720. doi: 10.1093/eurheartj/ehi471
34. Zhang H., El-Am E.A., Thaden J.J., et al. Atrial fibrillation is not an independent predictor of outcome in patients with aortic stenosis // Heart. 2020. Vol. 106, N 4. P. 280–286.
doi: 10.1136/heartjnl-2019-314996
35. Ancona R., Pinto S.C. Epidemiology of aortic valve stenosis (AS) and of aortic valve incompetence (AI): is the prevalence of AS/AI similar in different parts of the world? // e-Journal of Cardiology Practice. 2020. Vol. 18, N 10. Режим доступа: https://www.escardio.org/Journals/E-Journal-of-Cardiology-Practice/Volume-18/epidemiology-of-aortic-.... Дата обращения: 10.11.2023.
36. Бокерия Л.А., Амирагов Р.А., Асатрян Т.В., и др. Аортальный стеноз. Клинические рекомендации. Mосква: Минздрав России, 2020.
37. d'Arcy J.L., Coffey S., Loudon M.A., et al. Large-scale community echocardiographic screening reveals a major burden of undiagnosed valvular heart disease in older people: the OxVALVE Population Cohort Study // Eur Heart J. 2016. Vol. 37, N 47. P. 3515–3522. doi: 10.1093/eurheartj/ehw229
38. Shu C., Chen S., Qin T., et al. Prevalence and correlates of valvular heart diseases in the elderly population in Hubei, China // Sci Rep. 2016. N 6. P. 27253. doi: 10.1038/srep27253
39. Nishimura R.A., Otto C.M., Bonow R.O., et al. 2014 AHA/ACC guideline for the management of patients with valvular heart disease: executive summary: a report of the American College of Cardiology / American Heart Association task force on practice guidelines // Circulation. 2014. Vol. 129, N 23. P. 2440–2492. doi: 10.1161/CIR.0000000000000029. Erratum in: Circulation. 2014. Vol. 129, N 23. P. e650.
40. Otto C.M., Nishimura R.A., Bonow R.O., et al. 2020 ACC/AHA Guideline for the management of patients with valvular heart disease: A report of the American College of Cardiology / American Heart Association Joint Committee on clinical practice guidelines // Circulation. 2021. Vol. 143, N 5. P. e72–e227. doi: 10.1161/CIR.0000000000000923 Erratum in: Circulation. 2021. Vol. 143, N 5. P. e229. Erratum in: Circulation. 2023. Vol. 148, N 8. P. e8.
41. Bustamante-Munguira J., Centella T., Polo L., Hornero F. Cirugía cardiovascular en España en el año 2014. Registro de intervenciones de la Sociedad Española de Cirugía Torácica-Cardiovascular // Cirugía Cardiovascular. 2015. Vol. 22, N 6. P. 297–313. doi: 10.1016/j.circv.2015.09.008
42. Iung B., Baron G., Butchart E.G., et al. A prospective survey of patients with valvular heart disease in Europe: the Euro Heart Survey on Valvular Heart Disease // Eur Heart J. 2003.
Vol. 24, N 13. P. 1231–1243. doi: 10.1016/s0195-668x(03)00201-x
43. Banovic M., DaCosta M. Degenerative mitral stenosis: from pathophysiology to challenging interventional treatment // Curr Probl Cardiol. 2019. Vol. 44, N 1. P. 10–35.
doi: 10.1016/j.cpcardiol.2018.03.004
44. Mensah G.A., Roth G.A., Fuster V. The global burden of cardiovascular diseases and risk factors: 2020 and beyond // J Am Coll Cardiol. 2019. Vol. 74, N. 20. P. 2529–2532. 
doi: 10.1016/j.jacc.2019.10.009
45. Prihadi E.A., van der Bijl P., Gursoy E., et al. Development of significant tricuspid regurgitation over time and prognostic implications: new insights into natural history // Eur Heart J. 2018. Vol. 39, N 39. P. 3574–3581. doi: 10.1093/eurheartj/ehy352
46. Комлев А.Е., Саидова М.А., Имаев Т.Э., Акчурин Р.С. Диагностика и транскатетерные методы лечения трикуспидальной регургитации // Кардиологический вестник. 2022. Т. 17, № 2. С. 5–15. doi: 10.17116/Cardiobulletin2022170215
47. Riesenhuber M., Spannbauer A., Gwechenberger M., et al. Pacemaker lead-associated tricuspid regurgitation in patients with or without pre-existing right ventricular dilatation // Clin Res Cardiol. 2021. Vol. 110, N 6. P. 884–894. doi: 10.1007/s00392-021-01812-3
48. Vasques F., Lucenteforte E., Paone R., et al. Outcome of patients aged ≥80 years undergoing combined aortic valve replacement and coronary artery bypass grafting: a systematic review and meta-analysis of 40 studies // Am Heart J. 2012. Vol. 164, N 3. P. 410.e.1–418.e1. doi: 10.1016/j.ahj.2012.06.019
49. Brown J.M., O’Brien S.M., Wu C., et al. Isolated aortic valve replacement in North America comprising 108,687 patients in 10 years: changes in risks, valve types, and outcomes in the Society of Thoracic Surgeons National Database // J Thorac Cardiovasc Surg. 2009. Vol. 137, N 1. P. 82–90. doi: 10.1016/j.jtcvs.2008.08.015
50. Bonnet V., Boisselier C., Saplacan V., et al. The role of age and comorbidities in postoperative outcome of mitral valve repair: A propensity-matched study // Medicine (Baltimore). 2016. Vol. 95, N 25. P. 3938. doi: 10.1097/MD.0000000000003938
51. GBD 2013 Mortality and Causes of Death Collaborators. Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013 // Lancet. 2015. Vol. 385, N 9963. P. 117–171. doi: 10.1016/S0140-6736(14)61682-2
52. Барбараш О.Л., Одаренко Ю.Н., Кондюкова Н.В. Показатели качества жизни в оценке эффективности хирургического лечения у пациентов с приобретенными пороками сердца при использовании биологических и механических протезов клапанов сердца // Креативная кардиология. 2019. Т. 3, № 1. С. 28–39. 
doi: 10.24022/1997-3187-2019-13-1-28-39
53. Watkins D.A., Johnson C.O., Colquhoun S.M., et al. Global, Regional, and National Burden of Rheumatic Heart Disease, 1990–2015 // N Engl J Med. 2017. Vol. 377, N 8. P. 71322.
doi: 10.1056/NEJMoa1603693
54. Arora S., Ramm C.J., Bahekar A.A., Vavalle J.P. Evaluating Health of Emerging Economies Through the Eyes of Heart Valve Disease in the Transcatheter Era // Glob Heart. 2017.
Vol. 12, N 4. P. 301–304. doi: 10.1016/j.gheart.2017.01.016
55. Abramowitz Y., Jilaihawi H., Chakravarty T. Mitral Annulus Calcification // J Am Coll Cardiol. 2015. Vol. 66, N 17. P. 1934–1941. doi: 10.1016/j.jacc.2015.08.872
56. Сазоненков М.А., Исматов Х.Х., Эрнст Э.Э., и др. Оперированный порок митрального клапана. Структура этиологии и видов оперативных вмешательств за период 2015–2020 гг. в кардиохирургическом отделении БОКБ Святителя Иоасафа // Актуальные проблемы медицины. 2020. Т. 43, № 4. С. 590–602. 
doi: 10.18413/2687-0940-2020-43-4-590-602
57. Habib G., Erba P.A., Iung B., et al. Clinical presentation, aetiology and outcome of infective endocarditis. Results of the ESC-EORP EURO-ENDO (European infective endocarditis) registry: a prospective cohort study // Eur Heart J. 2019. Vol. 40, N 39. P. 3222–3232. doi: 10.1093/eurheartj/ehz620. Erratum in: Eur Heart J. 2020. Vol. 41, N 22. P. 2091.
58. DesJardin, J.T., Chikwe J., Hahn R.T., et al. Sex Differences and Similarities in Valvular Heart Disease // Circ Res. 2022. Vol. 30, N 4. P. 455–473.
doi: 10.1161/CIRCRESAHA.121.319914
59. Бокерия Л.А., Климчук И.Я. Недостаточность митрального клапана у пациентов с фибрилляцией предсердий. Современное состояние проблемы, подход к диагностике и комплексному хирургическому лечению // Анналы аритмологии. 2015. Т. 12, № 4. С. 201–214. doi: 10.15275/annaritmol.2015.4.2
60. Евтушенко В.В., Макогончук И.С., Евтушенко А.В. Правила и принципы отбора пациентов на хирургическое лечение приобретенных пороков сердца, осложненных фибрилляцией предсердий // Сибирский медицинский журнал клинической и экспериментальной медицины. 2017. Т. 32, № 3. С. 29–34. 
doi: 10.29001/2073-8552-2017-32-3-29-34
61. Семенова Е.И., Железнев С.И., Семенов И.И., и др. Протезирование клапанов сердца у больных пожилого возраста. Факторы риска: ассоциированные заболевания // Сибирский журнал клинической и экспериментальной медицины. 2007. Т. 22, № 3. С. 97–100.
62. Charalampopoulos A., Lewis R., Hickey P., et al. Pathophysiology and Diagnosis of Pulmonary Hypertension Due to Left Heart Disease // Front Med (Lausanne). 2018. N 5. P. 174.
doi: 10.3389/fmed.2018.00174
63. Никищенкова Ю.В., Никифоров В.С., Желтышева Ж.А., и др. Приобретенные пороки сердца у пациентов пожилого и старческого возраста. Актуальные вопросы клиники, диагностики и лечения заболеваний у ветеранов Великой Отечественной войны в многопрофильном стационаре. Сб. науч. трудов. Вып. 7 / под ред. М.Ю. Кабанова. Санкт-Петербург: РГПУ им. А.И. Герцена, 2015. С. 136–141.
64. Windecker S., Kolh P., Alfonso F., et al. 2014 ESC/EACTS Guidelines on myocardial revascularization: The Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS) Developed with the special contribution of the European Association of Percutaneous Cardiovascular Interventions (EAPCI) // Eur Heart J. 2014. Vol. 35, N 37. P. 2541–2619. doi: 10.1093/eurheartj/ehu278
65. Петров В.С. Распространенность эндотелиальной дисфункции и дислипидемии у пациентов с хронической ревматической болезнью сердца // Медицинский совет. 2019. Т. 12. С. 14–18. doi: 10.21518/2079-701X-2019-12-14-18
66. Emren Z.Y., Emren S.V., Kılıçaslan B., et al. Evaluation of the prevalence of coronary artery disease in patients with valvular heart disease // J Cardiothorac Surg. 2014. N 9. P. 153. 
doi: 10.1186/s13019-014-0153-1
67. Караськов А.М., Железнев С.И., Семенова Е.И., и др. Артериальная гипертензия как фактор риска при оперативном лечении приобретенных пороков сердца у больных старше 60 лет // ­Патология кровообращения и кардиохирургия. 2007. Т. 2. С. 3–6.
68. Скопин И.И., Отаров А.М. Предоперационные факторы риска при протезировании аортального клапана у больных пожилого и старческого возраста // Бюллетень НЦССХ им. А.Н. Бакулева РАМН. Сердечно-сосудистые заболевания. 2017. Т. 18, № 3. С. 243–255. doi: 10.24022/1810-0694-2017-18-3-243-25
69. Бараховская Т.В., Суворова Е.А., Попова Е.С., Калягин А.Н. Сравнительный анализ течения, исходов, особенностей лечения дегенеративных и ревматических пороков сердца // Сибирский медицинский журнал (Иркутск). 2017. Т. 150, № 3. С. 19–22.
70. Akiyoshi T., Ota H., Iijima K., et al. A novel organ culture model of aorta for vascular calcification // Atherosclerosis. 2016. N 244. P. 51–58. doi: 10.1016/j.atherosclerosis.2015.11.005
71. Guler S., Varol E. The relation between echocardiographic epicardial fat thickness and mitral annular calcification // Afr Health Sci. 2019. Vol. 19, N 1. P. 1657–1664.
doi: 10.4314/ahs.v19i1.41
72. Гриценко О.В., Чумакова Г.А., Ельчанинова С.А., и др. Липотоксическое поражение миокарда при ожирении // CardioСоматика. 2017. Т. 8, № 4. С. 36–40. doi: https://doi.org/10.26442/CS45386
73. Синицкий М.Ю., Понасенко А.В., Груздева О.В. Генетический профиль и секретом адипоцитов висцеральной и подкожной жировой ткани у пациентов с сердечно-сосудистыми заболеваниями // Комплексные проблемы ­сердечно-сосудистых заболеваний. 2017. Т. 6, № 3. С. 155–165. doi: 10.17802/2306-1278-2017-6-3-155-165
74. Alnabelsi T.S., Alhamshari Y., Mulki R.H., et al. Relation Between Epicardial Adipose and Aortic Valve and Mitral Annular Calcium Determined by Computed Tomography in Subjects Aged ≥65 Years // Am J Cardiol. 2016. Vol. 118, N 7. P. 1088–1093. doi: 10.1016/j.amjcard.2016.07.012

________________________________________________

1. Shlyakhto EV, editor. Cardiology. National Guide. 2nd edition, revised and expanded. Moscow: GEOTAR-Media; 2019. (In Russ).
2. Santangelo G, Bursi F, Faggiano A, et al. The Global Burden of Valvular Heart Disease: From Clinical Epidemiology to Management. J Clin Med. 2023;12(6):2178.
doi: 10.3390/jcm12062178
3. Sharma T, Krishnan AM, Lahoud R, et al. National Trends in TAVR and SAVR for Patients With Severe Isolated Aortic Stenosis. J Am Coll Cardiol. 2022;80(21):2054–2056.
doi: 10.1016/j.jacc.2022.08.787
4. Golukhova EZ. Report on the scientific and clinical activity of the Bakoulev National Medical Research Center for Cardiovascular Surgery for 2021 and development prospects. The Bulletin of Bakoulev Center. Cardiovascular Diseases. 2022;23(S):5–111. (In Russ). doi: 10.24022/1810-0694-2022-23S
5. van der Heijden CAJ, Verheule S, Olsthoorn J, et al. Postoperative atrial fibrillation and atrial epicardial fat: Is there a link? Int J Cardiol Heart Vasc. 2022;(39):100976.
doi: 10.1016/j.ijcha.2022.100976
6. Deeva NS, Shabaldin AV, Antonova LV. The role of calcium metabolism disorders in induction of hypersensitivity in cardiovascular diseases. Bulletin of Siberian Medicine. 2021;20(3):141–151. (In Russ). doi: 10.20538/1682-0363-2021-3-141-151
7. Koenen M, Hill MA, Cohen P, Sowers JR. Obesity, Adipose Tissue and Vascular Dysfunction. Circ Res. 2021;128(7):951–968. doi: 10.1161/CIRCRESAHA.121.318093
8. Iung B, Delgado V, Rosenhek R, et al. Contemporary Presentation and Management of Valvular Heart Disease: The EURObservational Research Programme Valvular Heart Disease II Survey. Circulation. 2019;140(14):1156–1169. doi: 10.1161/CIRCULATIONAHA.119.041080
9. Go AS, Mozaffarian D, Roger VL, et al. Heart disease and stroke statistics — 2014 update: a report from the American Heart Association. Circulation. 2014;129(3):e28–e292. 
doi: 10.1161/01.cir.0000441139.02102.80
10. Aluru JS, Barsouk A, Saginala K, et al. Valvular Heart Disease Epidemiology. Med Sci (Basel). 2022;10(2):32. doi: 10.3390/medsci10020032
11. Shlyakhto EV, editor. Cardiology. National Guide. 2nd edition, revised and expanded. Moscow: GEOTAR-Media; 2015. (In Russ).
12. Georgikia RK, Kharitonov GI. Modern aspects of diagnosis and surgical treatment of acquired heart defects. Prakticheskaya meditsina. 2003;(2):25–26. (In Russ).
13. Rubanenko AO, D'yachkov VA, Shchukin YuV, et al. Аcquired valvular heart diseases: clinical picture and diagnostics. Cardiology: News, Opinions, Training. 2019;7(3):26–36. (In Russ). doi: 10.24411/2309-1908-2019-13003
14. Order of the Ministry of Health of the Russian Federation No. 283 of 30 November 1993 «O sovershenstvovanii sluzhby funktsional'noi diagnostiki v uchrezhdeniyakh zdravookhraneniya Rossiiskoi Federatsii». Available from: https://normativ.kontur.ru/document?moduleId=1&documentId=71530. Accessed: 10.11.2023. (In Russ).
15. Tyurin IE. Radiology in the Russian Federation in 2016. Journal of radiology and nuclear medicine. 2017;98(4):219–226. (In Russ). doi: 10.20862/0042-4676-2017-98-4-219-226
16. Sachek OI, Beresten' NF, Tolmachev DA, Oskov YuI. Provision and staffing of outpatient clinics by doctors of functional diagnostics in the Russian Federation, federal districts and pilot subjects in 2012–2016. Medical Alphabet. 2018;1(14):7–12. (In Russ).
17. Beckmann A, Funkat AK, Lewandowski J, et al. German heart surgery report 2015: the annual updated registry of the German society for thoracic and cardiovascular surgery. Thorac Cardiovasc Surg. 2016;64(6):462–474. doi: 10.1055/s-0036-1592124
18. Khubulava GG, Gulyaev NI, Kravchuk VN, et al. Incidence of degenerative aortic stenosis in the patterns of valvular heart disease. Russian Journal of Thoracic and Cardiovascular Surgery.  2018;60(1):28–35. (In Russ). doi: 10.24022/0236-2791-2018-60-1-28-35
19. Semenov VYu, Samorodskaya IV, Larina VN, Andreev EM. Mortality from acquired heart disease during a 15 year period in the Russian Federation and the United States and an analysis of the factors influencing their formation. Kreativnaya kardiologiya. 2017;11(3):235–246. (In Russ). doi: 10.24022/1997-3187-2017-11-2-235-246
20. Yadgir S, Johnson CO, Aboyans V, et al. Global, regional, and national burden of calcific aortic valve and degenerative mitral valve diseases, 1990–2017. Circulation. 2020;141(21):1670–1680. doi: 10.1161/CIRCULATIONAHA.119.043391
21. Shariff M, Kumar A, Hirji SA, et al. Ten Years Mortality Trends of Tricuspid Regurgitation in the United States, 2008 to 2018. Am J Cardiol. 2021;(140):156–157.
doi: 10.1016/j.amjcard.2020.11.024
22. Pierard S, Seldrum S, de Meester C, et al. Incidence, determinants, and prognostic impact of operative refusal or denial in octogenarians with severe aortic stenosis. Ann Thorac Surg. 2011;91(4):1107–1112. doi: 10.1016/j.athoracsur.2010.12.052
23. Huang X, Dhruva SS, Yuan X, et al. Characteristics, interventions and outcomes of patients with valvular heart disease hospitalised in China: a cross-sectional study. BMJ Open. 2021;11(11):e052946. doi: 10.1136/bmjopen-2021-052946
24. Izumi C, Matsuyama R, Yamabe K, et al. In-Hospital Outcomes of Heart Failure Patients with Valvular Heart Disease: Insights from Real-World Claims Data. Clinicoecon Outcomes Res. 2023;(15):349–360. doi: 10.2147/CEOR.S405079
25. Smith PK, Puskas JD, Ascheim DD, et al. Surgical treatment of moderate ischemic mitral regurgitation. N Engl J Med. 2014;371(23):2178–2188. doi: 10.1056/NEJMoa1410490
26. Virk SA, Sriravindrarajah A, Dunn D, et al. A meta-analysis of mitral valve repair versus replacement for ischemic mitral regurgitation. Ann Cardiothorac Surg. 2015;4(5):400–410. 
doi: 10.3978/j.issn.2225-319X.2015.09.06
27. Sabate M, Canovas S, Garcia E, et al. In-hospital and mid-term predictors of mortality after transcatheter aortic valve implantation: data from the TAVI National Registry 2010–2011. Rev Esp Cardiol (Engl Ed). 2013;66(12):949–958. doi: 10.1016/j.rec.2013.07.003
28. Rodés-Cabau J, Dumont E, De LaRochellière R, et al. Feasibility and initial results of percutaneous aortic valve implantation including selection of the transfemoral or transapical approach in patients with severe aortic stenosis. Am J Cardiol. 2008;102(9):1240–1246. doi: 10.1016/j.amjcard.2008.06.061
29. Dreyfus J, Audureau E, Bohbot Y, et al. TRI-SCORE: a new risk score for in-hospital mortality prediction after isolated tricuspid valve surgery. Eur Heart J. 2022;43(7):654–662.
doi: 10.1093/eurheartj/ehab679
30. Coffey S, Harper AR, Cairns BJ, et al. Clinical information has low sensitivity for postmortem diagnosis of heart valve disease. Heart. 2017;103(13):1031–1035.
doi: 10.1136/heartjnl-2016-310718
31. Marangou J, Beaton A, Aliku TO, et al. Echocardiography in Indigenous Populations and Resource Poor Settings. Heart Lung Circ. 2019;28(9):1427–1435.
doi: 10.1016/j.hlc.2019.05.176
32. Kang D, Bach DS, Chetcuti S, et al. Mortality Predictors in Patients Referred for but Not Undergoing Transcatheter Aortic Valve Replacement. Am J Cardiol. 2015;116(6):919–924.
doi: 10.1016/j.amjcard.2015.06.014
33. Iung B, Cachier A, Baron G, et al. Decision-making in elderly patients with severe aortic stenosis: why are so many denied surgery? Eur Heart J. 2005;26(24):2714–2720.
doi: 10.1093/eurheartj/ehi471
34. Zhang H, El-Am EA, Thaden JJ, et al. Atrial fibrillation is not an independent predictor of outcome in patients with aortic stenosis. Heart. 2020;106(4):280–286.
doi: 10.1136/heartjnl-2019-314996
35. Ancona R, Pinto SC. Epidemiology of aortic valve stenosis (AS) and of aortic valve incompetence (AI): is the prevalence of AS/AI similar in different parts of the world? e-Journal of Cardiology Practice. 2020;(18):10. Available from: https://www.escardio.org/Journals/E-Journal-of-Cardiology-Practice/Volume-18/epidemiology-of-aortic-.... Accessed: 10.11.2023.
36. Bockeria LA, Amiragov RA, Asatryan TV, et al. Aortic stenosis. Clinical recommendations. Moscow: Minzdrav Rossii; 2020. (In Russ).
37. d'Arcy JL, Coffey S, Loudon MA, et al. Large-scale community echocardiographic screening reveals a major burden of undiagnosed valvular heart disease in older people: the OxVALVE Population Cohort Study. Eur Heart J. 2016;37(47):3515–3522. doi: 10.1093/eurheartj/ehw229
38. Shu C, Chen S, Qin T, et al. Prevalence and correlates of valvular heart diseases in the elderly population in Hubei, China. Sci Rep. 2016;(6):27253. doi: 10.1038/srep27253
39. Nishimura RA, Otto CM, Bonow RO, et al. 2014 AHA/ACC guideline for the management of patients with valvular heart disease: executive summary: a report of the American College of Cardiology / American Heart Association task force on practice guidelines. Circulation. 2014;129(23):2440–2492. doi: 10.1161/CIR.0000000000000029. Erratum in: Circulation. 2014;129(23):e650.
40. Otto CM, Nishimura RA, Bonow RO, et al. 2020 ACC/AHA Guideline for the management of patients with valvular heart disease: A report of the American College of Cardiology / American Heart Association Joint Committee on clinical practice guidelines. Circulation. 2021;143(5):e72–e227. doi: 10.1161/CIR.0000000000000923. Erratum in: Circulation. 2021;143(5):e229. Erratum in: Circulation. 2023;148(8):e8.
41. Bustamante-Munguira J, Centella T, Polo L, Hornero F. Cardiovascular surgery in Spain during 2014. The registry of the Spanish Society of Thoracic-Cardiovascular Surgery. Cirugía Cardiovascular. 2015;22(6):297–313. (In Spanish). doi: 10.1016/j.circv.2015.09.008
42. Iung B, Baron G, Butchart EG, et al. A prospective survey of patients with valvular heart disease in Europe: The Euro Heart Survey on Valvular Heart Disease. Eur Heart J. 2003;24(13):1231–1243. doi: 10.1016/s0195-668x(03)00201-x
43. Banovic M, DaCosta M. Degenerative Mitral Stenosis: From Pathophysiology to Challenging Interventional Treatment. Curr Probl Cardiol. 2019;44(1):10–35.
doi: 10.1016/j.cpcardiol.2018.03.004
44. Mensah GA, Roth GA, Fuster V. The Global Burden of Cardiovascular Diseases and Risk Factors: 2020 and Beyond. J Am Coll Cardiol. 2019;74(20):2529–2532.
doi: 10.1016/j.jacc.2019.10.009
45. Prihadi EA, van der Bijl P, Gursoy E, et al. Development of significant tricuspid regurgitation over time and prognostic implications: new insights into natural history. Eur Heart J. 2018;39(39):3574–3581. doi: 10.1093/eurheartj/ehy352
46. Komlev AE, Saidova MA, Imaev TE, Akchurin RS. Diagnosis and transcatheter treatment of tricuspid regurgitation. Russian Cardiology Bulletin. 2022;17(2):5–15. (In Russ).
doi: 10.17116/Cardiobulletin2022170215
47. Riesenhuber M, Spannbauer A, Gwechenberger M, et al. Pacemaker lead-associated tricuspid regurgitation in patients with or without pre-existing right ventricular dilatation. Clin Res Cardiol. 2021;110(6):884–894. doi: 10.1007/s00392-021-01812-3
48. Vasques F, Lucenteforte E, Paone R, et al. Outcome of patients aged ≥80 years undergoing combined aortic valve replacement and coronary artery bypass grafting: a systematic review and meta-analysis of 40 studies. Am Heart J. 2012;164(3):410.e1–418.e1. doi: 10.1016/j.ahj.2012.06.019
49. Brown JM, O'Brien SM, Wu C, et al. Isolated aortic valve replacement in North America comprising 108,687 patients in 10 years: changes in risks, valve types, and outcomes in the Society of Thoracic Surgeons National Database. J Thorac Cardiovasc Surg. 2009;137(1):82–90. doi: 10.1016/j.jtcvs.2008.08.015
50. Bonnet V, Boisselier C, Saplacan V, et al. The role of age and comorbidities in postoperative outcome of mitral valve repair: A propensity-matched study. Medicine (Baltimore). 2016;95(25):e3938. doi: 10.1097/MD.0000000000003938
51. GBD 2013 Mortality and Causes of Death Collaborators. Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2015;385(9963):117–171. doi: 10.1016/S0140-6736(14)61682-2
52. Barbarash OL, Odarenko YuN, Kondyukova NV. Quality of life indicators in evaluating the efficiency of surgical treatment in patients with acquired heart diseases undergoing bioprosthetic and mechanical heart valve replacement. Kreativnaya kardiologiya. 2019;3(1):28–39. (In Russ). doi: 10.24022/1997-3187-2019-13-1-28-39
53. Watkins DA, Johnson CO, Colquhoun SM, et al. Global, Regional, and National Burden of Rheumatic Heart Disease, 1990–2015. N Engl J Med. 2017;377(8):713–722.
doi: 10.1056/NEJMoa1603693
54. Arora S, Ramm CJ, Bahekar AA, Vavalle JP. Evaluating Health of Emerging Economies Through the Eyes of Heart Valve Disease in the Transcatheter Era. Glob Heart.
2017;12(4):301–304. doi: 10.1016/j.gheart.2017.01.016
55. Abramowitz Y, Jilaihawi H, Chakravarty T, et al. Mitral Annulus Calcification. J Am Coll Cardiol. 2015;66(17):1934–1941. doi: 10.1016/j.jacc.2015.08.872
56. Sazonenkov MA, Ismatov HH, Ernst EE, et al. Operated mitral valve disease. The structure of the etiology and types of surgical intervention for the period 2015–2020 in the cardiac surgery department of Belgorod Regional Clinical Hospital. Challenges in modern medicine. 2020;43(4):590–602. (In Russ). doi: 10.18413/2687-0940-2020-43-4-590-602
57. Habib G, Erba PA, Iung B, et al. Clinical presentation, aetiology and outcome of infective endocarditis. Results of the ESC-EORP EURO-ENDO (European infective endocarditis) registry: a prospective cohort study. Eur Heart J. 2019;40(39):3222–3232. doi: 10.1093/eurheartj/ehz620. Erratum in: Eur Heart J. 2020;41(22):2091.
58. DesJardin JT, Chikwe J, Hahn RT, et al. Sex Differences and Similarities in Valvular Heart Disease. Circ Res. 2022;130(4):455–473. doi: 10.1161/CIRCRESAHA.121.319914
59. Bockeria LA, Klimchuk IYa. Mitral regurgitation in patients with atrial fibrillation. Current state of the problem, approaches to diagnosis and complex surgical treatment. Annaly aritmologii. 2015;12(4):201–214. (In Russ). doi: 10.15275/annaritmol.2015.4.2
60. Evtushenko VV, Makogonchuk IS, Evtushenko AV. Rules and principles of patient selection for surgical treatment of acquired heart diseases complicated by atrial fibrillation. The Siberian Journal of Clinical and Experimental Medicine. 2017;32(3):29–34. (In Russ). doi: 10.29001/2073-8552-2017-32-3-29-34
61. Semenova EI, Zheleznev SI, Semenov II, et al. Cardiac valves’ prosthetics in elderly patients. Risk factors: associated morbidity. The Siberian Journal of Clinical and Experimental Medicine. 2007;22(3):97–100. (In Russ).
62. Charalampopoulos A, Lewis R, Hickey P, et al. Pathophysiology and Diagnosis of Pulmonary Hypertension Due to Left Heart Disease. Front Med (Lausanne). 2018;(5):174.
doi: 10.3389/fmed.2018.00174
63. Nikishchenkova YuV, Nikiforov VS, Zheltysheva ZhA, et al. Acquired heart defects in elderly and senile patients. Current issues of clinical practice, diagnosis and treatment of diseases among veterans of the Great Patriotic War in a multidisciplinary hospital. Collection of scientific papers. Vol. 7. Kabanov MYu, editor. St. Petersburg: RGPU im. A.I. Gertsena; 2015. P. 136–141. (In Russ).
64. Windecker S, Kolh P, Alfonso F, et al. 2014 ESC/EACTS Guidelines on myocardial revascularization: The Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS) Developed with the special contribution of the European Association of Percutaneous Cardiovascular Interventions (EAPCI). Eur Heart J. 2014;35(37):2541–2619. doi: 10.1093/eurheartj/ehu278
65. Petrov VS. Prevalence of endothelial dysfunction and dyslipidemia in patients with chronic rheumatic heart disease. Meditsinskiy sovet = Medical Council. 2019;(12):14–18. (In Russ). doi: 10.21518/2079-701X-2019-12-14-18
66. Emren ZY, Emren SV, Kılıçaslan B, et al. Evaluation of the prevalence of coronary artery disease in patients with valvular heart disease. J Cardiothorac Surg. 2014;(9):153.
doi: 10.1186/s13019-014-0153-1
67. Karas'kov AM, Zheleznev SI, Semenova EI, et al. Arterial hypertension as a risk factor in surgical treatment of acquired heart defects in patients over 60 years of age. Patologiya krovoobrashcheniya i kardiokhirurgiya. 2007;(2):3–6. (In Russ).
68. Skopin II, Otarov AM. Preoperative risk factors in elderly patients undergoing aortic valve replacement. The Bulletin of Bakoulev Center. Cardiovascular Diseases. 2017;18(3):243–255. (In Russ). doi: 10.24022/1810-0694-2017-18-3-243-25
69. Barakhovskaya TV, Suvorova EA, Popova ES, Kalyagin AN. The comparative analysis of the course, outputs and the features of treatment of degenerative and rheumatic heart diseases. Siberian Medical Journal (Irkutsk). 2017;150(3):19–22. (In Russ).
70. Akiyoshi T, Ota H, Iijima K, et al. A novel organ culture model of aorta for vascular calcification. Atherosclerosis. 2016;(244):51–58. doi: 10.1016/j.atherosclerosis.2015.11.005
71. Guler S, Varol E. The relation between echocardiographic epicardial fat thickness and mitral annular calcification. Afr Health Sci. 2019;19(1):1657–1664. doi: 10.4314/ahs.v19i1.41
72. Gritsenko OV, Chumakova GA, Elchaninova SA, et al. Lipotoxicity damage of myocardium in obesity. CardioSomatics. 2017;8(4):36–40. (In Russ). doi: https://doi.org/10.26442/CS45386
73. Sinitskiy MY, Ponasenko AV, Gruzdeva OV. Genetic profile and secretome of adipocytes from visceral and subcutaneous adipose tissue in patients with cardiovascular diseases. Complex Issues of Cardiovascular Diseases. 2017;(3):155–165. (In Russ). doi: 10.17802/2306-1278-2017-6-3-155-165
74. Alnabelsi TS, Alhamshari Y, Mulki RH, et al. Relation Between Epicardial Adipose and Aortic Valve and Mitral Annular Calcium Determined by Computed Tomography in Subjects Aged ≥65 Years. Am J Cardiol. 2016;118(7):1088–1093. doi: 10.1016/j.amjcard.2016.07.012

Е.В. Дрень*, И.Н. Ляпина, Т.Б. Печерина, О.Л. Барбараш

НИИ комплексных проблем сердечно-сосудистых заболеваний, Кемерово, Россия
*e.tolpekina.v@mail.ru

________________________________________________

Elena V. Dren’*, Irina N. Lyapina, Tamara B. Pecherina, Olga L. Barbarash

Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo, Russia
*e.tolpekina.v@mail.ru