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Эффективность и переносимость препарата Антистакс® у пациентов с хронической венозной недостаточностью – обзор результатов двойного слепого плацебо-контролируемого мультицентрового исследования
Эффективность и переносимость препарата Антистакс® у пациентов с хронической венозной недостаточностью – обзор результатов двойного слепого плацебо-контролируемого мультицентрового исследования
М.Н.Кудыкин. Эффективность и переносимость препарата Антистакс® у пациентов с хронической венозной недостаточностью – обзор результатов двойного слепого плацебо-контролируемого мультицентрового исследования. Consilium Medicum. Хирургия (Прил.). 2011; 2: 13-17.
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Аннотация
Обзор подготовил доктор медицинских наук М.Н.Кудыкин
Полный текст
Список литературы
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3. Rabe E, Pannier-Fischer F, Bromen K et al. Bonner Venenstudie der Deutschen Gesellschaft für Phlebologie – Epidemiologische Untersuchung zur Frage der Haufigkeit und Auspragung von chronischen Venenkrankheiten in der städtischen und ländlichen Wohnbevolkerung. Phlebologie 2003; 32: 1–14.
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5. Frick RW. Three treatments for chronic venous insufficiency: escin, hydroxyethylrutoside and daflon. Angiology 2000; 51 (3): 197–205.
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7. Pittler MH, Ernst E. Horse chestnut seed extract for chronic venous insufficiency. The Cochrane Library 2001; 3.
8. Kalus U, Koscielny J, Grigorov A et al. Clinical improvement of cutaneous microcirculation and oxygen supply in patients with chronic venous insufficiency by orally administered extract of red vine leaves AS 195. A randomised, doubleblind, placebo-controlled cross-over study. Drugs in R&D 2004; 5: 63–71.
9. Kiesewetter H, Koscielny J, Kalus U et al. Efficacy of orally administered extract of red vine leaf AS 195 (folia vitis viniferae) in chronic venous insufficiency (stages I–II). A randomized, double-blind, placebo-controlled trial. Arzneimittelforschung 2000; 50: 109–17.
10. Martinez MJ, Bonfill X, Moreno RM et al. Phlebotonics for venous insufficiency, Cochrane Database Syst Rev 2005; 3: CD003229.
11. Rabe E, Stücker M, Ottillinger B. Water displacement leg volumetry in clinical studies – a discussion of error sources. BMC Med Res Methodol 2010; 10 (1): 5.
12. Marshall M, Loew D, Schwahn-Schreiber C. Hydroxyethylrutoside zur Behandlung der chronischen Veneninsuffizienz Grad I und II. Phlebologie 2005; 34: 157–64.
13. Marshall M, Medikamentöse Therapie von chronischen Venenleiden, TW Dermatologie 1993; 23: 244–8.
14. Cohen J. Statistical power analysis for the behavioral sciences, 2nd ed. Hillsdale, NJ: Erlbaum, 1988.
15. Gallenkemper G, Bulling BJ, Gerlach H et al. Leitlinien zur Diagnostik und Therapie der chronischen venösen Insuffizienz (CVI). Phlebologie 1998; 27: 32–5.
16. Deutsche Gesellschaft für Phlebologie, Diagnostik und Therapie des Ulcus cruris venosum. S3-Leitlinie der Deutschen Gesellschaft für Phlebologie, AWMF Guideline Register 2008; 037 (9).
17. Jünger M, Partsch B, Kahle B et al. Leitlinie: Phlebologischer Kompressionsverband (PKV), AWMF Guideline Register 2009; 037 (5).
18. Belcaro G, Cesarone MR, Ledda A et al. 5-Year control and treatment of edema and increased capillary filtration in venous hypertension and diabetic microangiopathy using O-(beta-hydroxyethyl)-rutosides: a prospective comparative clinical registry. Angiology 2008; 59 (Suppl. 1): 14S–20S.
2. Fowkes FG, Evans CJ, Lee AJ. Prevalence and risk factors of chronic venous insufficiency. Angiology 2001; 52 (Suppl. 1): S5–15.
3. Rabe E, Pannier-Fischer F, Bromen K et al. Bonner Venenstudie der Deutschen Gesellschaft für Phlebologie – Epidemiologische Untersuchung zur Frage der Haufigkeit und Auspragung von chronischen Venenkrankheiten in der städtischen und ländlichen Wohnbevolkerung. Phlebologie 2003; 32: 1–14.
4. Bergan JJ, Schmid-Schönbein GW. Coleridge Smith PD et al. Chronic venous disease. The New England Journal of Medicine 2006; 355: 488–98.
5. Frick RW. Three treatments for chronic venous insufficiency: escin, hydroxyethylrutoside and daflon. Angiology 2000; 51 (3): 197–205.
6. Pittler MH. Complementary therapies for chronic venous insufficiency. Focus on Alternative and Complementary Therapies 2001; 6: 3–5.
7. Pittler MH, Ernst E. Horse chestnut seed extract for chronic venous insufficiency. The Cochrane Library 2001; 3.
8. Kalus U, Koscielny J, Grigorov A et al. Clinical improvement of cutaneous microcirculation and oxygen supply in patients with chronic venous insufficiency by orally administered extract of red vine leaves AS 195. A randomised, doubleblind, placebo-controlled cross-over study. Drugs in R&D 2004; 5: 63–71.
9. Kiesewetter H, Koscielny J, Kalus U et al. Efficacy of orally administered extract of red vine leaf AS 195 (folia vitis viniferae) in chronic venous insufficiency (stages I–II). A randomized, double-blind, placebo-controlled trial. Arzneimittelforschung 2000; 50: 109–17.
10. Martinez MJ, Bonfill X, Moreno RM et al. Phlebotonics for venous insufficiency, Cochrane Database Syst Rev 2005; 3: CD003229.
11. Rabe E, Stücker M, Ottillinger B. Water displacement leg volumetry in clinical studies – a discussion of error sources. BMC Med Res Methodol 2010; 10 (1): 5.
12. Marshall M, Loew D, Schwahn-Schreiber C. Hydroxyethylrutoside zur Behandlung der chronischen Veneninsuffizienz Grad I und II. Phlebologie 2005; 34: 157–64.
13. Marshall M, Medikamentöse Therapie von chronischen Venenleiden, TW Dermatologie 1993; 23: 244–8.
14. Cohen J. Statistical power analysis for the behavioral sciences, 2nd ed. Hillsdale, NJ: Erlbaum, 1988.
15. Gallenkemper G, Bulling BJ, Gerlach H et al. Leitlinien zur Diagnostik und Therapie der chronischen venösen Insuffizienz (CVI). Phlebologie 1998; 27: 32–5.
16. Deutsche Gesellschaft für Phlebologie, Diagnostik und Therapie des Ulcus cruris venosum. S3-Leitlinie der Deutschen Gesellschaft für Phlebologie, AWMF Guideline Register 2008; 037 (9).
17. Jünger M, Partsch B, Kahle B et al. Leitlinie: Phlebologischer Kompressionsverband (PKV), AWMF Guideline Register 2009; 037 (5).
18. Belcaro G, Cesarone MR, Ledda A et al. 5-Year control and treatment of edema and increased capillary filtration in venous hypertension and diabetic microangiopathy using O-(beta-hydroxyethyl)-rutosides: a prospective comparative clinical registry. Angiology 2008; 59 (Suppl. 1): 14S–20S.
Авторы
М.Н.Кудыкин
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