Рассмотрены патофизиологические механизмы и принципы терапии хронической тазовой боли в гинекологической практике, возможности нестероидных противовоспалительных препаратов, в частности нимесулида.
The pathophysiological mechanisms and principles of treatment of chronic pelvic pain in gynecological practice, including nimesulide therapy, are considered and discussed in the article.
Key words: pelvic pain, treatment of pelvic pain, nimesulide.
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1. IASP. International Association for the study of pain «Pain terms» glossary. Pain 1986; 44–8 (Suppl. 3): 175–9.
2. Fall M, Baranowski AP, Fowler CJ et al. European Association of Urology. EAU guidelines on chronic pelvic pain. Eur Urol 2004; 46 (6): 681–9.
3. Khronicheskaia tazovaia bol'. Rukovodstvo dlia vrachei. Pod red. A.N.Belova, V.N.Krupina. M.: Antidor, 2007. [in Russian]
4. Lipscomb GH, Ling FW. Chronic pelvic pain. Med Clin North Am 1995; 79 (6): 1411–25.
5. ACOG Practice Bulletin No. 51. Chronic pelvic pain. Obstet Gynecol 2004; 103 (3): 589–605.
6. Steniaeva N.N., Apolikhina I.A. Khronicheskaia tazovaia bol': psikhosomaticheskie aspekty. Consilium Medicum. 2012; 6 (14): 19–21. [in Russian]
7. Royal College of Obstetricians and Gynaecologists. The Initial Management of Chronic Pelvic Pain 2005; Guideline 41.
8. Moore J, Kennedy S. causes of chronic pelvic pain. Baillieres Best Pract. Res Clin Obstet Gynaecol 2000; 14 (3): 389–402.
9. Stones RW, Mountfield J. Interventions for treating chronic pelvic pain in women. Cochrane Database Syst Rev 2000; 4: CD000387.
10. Weijenborg PT, Ter Kuile MM, Stones W. A cognitive behavioural based assessment of women with chronic pelvic pain. J Psychosom Obstet Gynaecol 2009; 30 (4): 262–8.
11. Howard FM, Berkley K. Сhronic abdominopelvic pain in women. Pain 2012: refresher courses, 14th world congress on pain. Seattle: IASP Press, 2012: p. 209–25.
12. Giudice LС. Сlinical practice. Endometriosis. N Engl J Med 2010; 362 (25): 2389–98.
13. Reshetniak V.K., Kukushkin M.L. Bol': fiziologicheskie i patofiziologicheskie aspekty. V kn.: B.B.Moroz (red.). Aktual'nye problemy patofiziologii (izbrannye lektsii). M.: Meditsina, 2001. [in Russian]
14. Strizhakov A.N., Dаvydov A.I. Endometrioz. Klinicheskie i teoreticheskie aspekty. M.: Meditsina, 1996. [in Russian]
15. Berkley KJ, Dmitrieva N, Curtis KS, Papka RE. Innervation of ectopic endometrium in a rat model of endometriosis. Proc Natl Acad Sci USA 2004; 101 (30): 11094–8. Epub 2004.
16. Berkley KJ, Rapkin AJ, Papka R.E. The pains of endometriosis. Science 2005; 308 (5728): 1587–9.
17. Anaf V, Simon P, El Nakadi I et al. Hyperalgesia, nerve infiltration and nerve growth factor expression in deep adenomyotic nodules, peritoneal and ovarian endometriosis. Hum Reprod 2002; 17 (7): 1895–900.
18. Anaf V, Chapron C, El Nakadi I et al. Pain, mast cells, and nerves in peritoneal, ovarian, and deep infiltrating endometriosis. Fertil Steril 2006; 86 (5): 1336–43. Epub 2006 Sep 27.
19. Danilov A.B. Neiropaticheskaia bol'. M.: Neiromedia, 2003. [in Russian]
20. Lund I, Lundeberg T. Aspects of pain, its assessment and evaluation from an acupuncture perspective. Acupunct Med 2006; 24 (3): 109–17.
21. Cummins TR, Rush AM. Voltage-gated sodium channel blockers for the treatment of neuropathic pain. Expert Rev Neurother 2007; 7 (11): 1597–612.
22. Million M, Wang L, Adelson DW et al. Pregabalin decreases visceral pain and prevents spinal neuronal activation in rats. Gut 2007; 56 (10): 1482–4.
23. Moalem G, Tracey DJ. Immune and inflammatory mechanisms in neuropathic pain. Brain Res Rev 2006; 51 (2): 240–64. Epub 2006.
24. Scholz J, Woolf CJ. The neuropathic pain triad: neurons, immune cells and glia. Nat Neurosci 2007; 10 (11): 1361–8.
25. Khirurgicheskoe lechenie sindroma tazovykh bolei v ginekologicheskoi klinike / Pod red. G.A.Cavitskogo, R.D.Ivanova, I.Iu.Shcheglova i dr. SPb.: ELBI-SPb., 2003. [in Russian]
26. Gunter J. Chronic pelvic pain: an integrated approach to diagnosis and treatment. Obstet Gynecol Surv 2003; 58 (9): 615–23.
27. Hahn L. Chronic pelvic pain in women. A condition difficult to diagnose – more than 70 different diagnoses can be considered. Lakartidningen 2001; 98 (15): 1780–5.
28. Wesselmann U. Clinical characteristics and pathophysiology of pelvic pain in women. Schmerz 2002; 16 (6): 467–75.
29. Zermann DH, Ishigooka M, Doggweiler R, Schmidt RA. Chronic Prostatitis: A myofascial pain syndrome? Infect Urol 1999; 12 (3): 84–92.
30. Khabirov F.A. Klinicheskaia nevrologiia pozvonochnika. Kazan': MPIK, 2002. [in Russian]
31. Chkhaidze I.Z., Niauri D.A. Problema boli v ginekologicheskoi praktike. Vestn. Sankt-Peterburgskogo universiteta. 2007; 11: 107–17. [in Russian]
32. Stav K, Dwyer PL, Roberts L. Pudendal neuralgia Fact or fiction? Obstet Gynecol Surv 2009; 64 (3):190–9.
33. Hruby S, Ebmer J, Dellon AL, Aszmann OC. Anatomy of pudendal nerve at urogenital diaphragm – new critical site for nerve entrapment. Urology 2005; 66 (5): 949–52.
34. EAU guidelines on chronic pelvic pain 2012.
35. Rainsford KD. Relationship of nimesulide safety to its pharmacokinetics: assessment of adverse reactions. Rheumatology (Oxford) 1999; 38 (Suppl. 1): 4–10.
36. Nasonov E.L. Effektivnost' i perenosimost' nesteroidnogo protivovospalitel'nogo preparata. Nimesulid: novye dannye. RMZh. 2001; 15: 6–8. [in Russian]
37. Misra SC, Pandey RM. Efficacy of drotaverine in irritable bowel syndrome: a double-blind, randomized, placebo-controlled clinical trial. Am J Gastroenterol 2000; 95: 2544 (Abs 455).
38. Niauri D.A., Popov E.N., Rusina E.I. i dr. Opyt primeneniia angioprotektorov (Ginkor-Fort) v lechenii bol'nykh s sindromom khronicheskikh tazovykh bolei. Regionarnoe krovoobrashchenie i mikrotsirkuliatsiia. 2003; 2 (6): 32–5. [in Russian]
39. Adamian L.V., Sharov M.N., Sonova M.M. i dr. Novyi vzgliad na khronicheskuiu tazovuiu bol' v ginekologicheskoi praktike. Effektivnaia farmakoterapiia. Nevrologiia i psikhiatriia. 2013; 3 (32): 24–9. [in Russian]
40. Repina V.V., Danilov A.B., Vorob'eva Iu.D., Fateeva V.V. Khronicheskaia tazovaia bol' – chto vazhno znat' nevrologu. RMZh. 2014: 51–4. [in Russian]
Авторы
Н.А.Осипова*, И.Е.Зазерская
ФГБУ Северо-Западный федеральный медицинский исследовательский центр им. В.А.Алмазова Минздрава России . 197341, Россия, Санкт-Петербург, ул. Аккуратова, д. 2 *naosipova@mail.ru
________________________________________________
N.A.Osipova*, I.E.Zazerskaya
V.A. Almazov Northwestern Federal Medical Research Center of the Ministry of Health of the Russian Federation. 197341, Russian Federation, Saint Petersburg, ul. Akkuratova, d. 2 *naosipova@mail.ru