Дифференциальная диагностика затяжного и хронического кашля у детей
Дифференциальная диагностика затяжного и хронического кашля у детей
Мизерницкий Ю.Л., Мельникова И.М., Удальцова Е.В. Дифференциальная диагностика затяжного и хронического кашля у детей. Consilium Medicum. 2017; 19 (11.1. Болезни органов дыхания): 7–16. DOI: 10.26442/2075-1753_19.11.1.7-16
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Mizernitskiy Yu.L., Melnikova I.M., Udaltsova E.V. Differential diagnosis of prolonged cough with chronic cough in children. Consilium Medicum. 2017; 19 (11.1. Respiratory Organs Diseases): 7–16. DOI: 10.26442/2075-1753_19.11.1.7-16
Дифференциальная диагностика затяжного и хронического кашля у детей
Мизерницкий Ю.Л., Мельникова И.М., Удальцова Е.В. Дифференциальная диагностика затяжного и хронического кашля у детей. Consilium Medicum. 2017; 19 (11.1. Болезни органов дыхания): 7–16. DOI: 10.26442/2075-1753_19.11.1.7-16
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Mizernitskiy Yu.L., Melnikova I.M., Udaltsova E.V. Differential diagnosis of prolonged cough with chronic cough in children. Consilium Medicum. 2017; 19 (11.1. Respiratory Organs Diseases): 7–16. DOI: 10.26442/2075-1753_19.11.1.7-16
Кашель – наиболее частый симптом как в амбулаторной, так и госпитальной практике. Мультифакторность кашля усложняет его этиологическую диагностику, особенно в условиях первичной врачебной помощи. В статье приведены современные данные о различном генезе кашля в зависимости от его длительности, клинических особенностей, продемонстрированы результаты собственных исследований, рассмотрены алгоритмы диагностики при кашле у детей. Особенно актуальной и практически востребованной является разработка клинических рекомендаций по дифференциальной диагностике заболеваний, сопровождающихся длительным кашлем в детском возрасте, что определяет дифференцированную терапию.
Ключевые слова: дети, затяжной и хронический кашель, алгоритмы дифференциальной диагностики.
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Cough is the most common symptom in both outpatient and hospital practice. The multifactoriality of the cough complicates its etiologic diagnosis, especially in the context of primary care. The article presents current data on the different genesis of cough depending on its duration and clinical features, shows the results of our own research, diagnostic algorithms for cough in children are considered.
The development of clinical guidelines for the differential diagnosis of diseases accompanied by a prolonged cough in childhood, which determines differential therapy, is particularly relevant and has demand in practice.
Key words: children, prolonged and chronic cough, algorithms for differential diagnosis
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1. Chuchalin A.G., Abrosimov V.N. Kashel'. M.: GEOTAR-Media, 2016. [in Russian]
2. Zaitsev A.A., Okovityi S.V. Kashel': differentsial'nyi diagnoz i ratsional'naia farmakoterapiia. Terapevt. arkhiv. 2014; 12: 85–91. [in Russian]
3. Mizernitskii Iu.L., Mel'nikova I.M. Mukoliticheskaia i otkharkivaiushchaia farmakoterapiia pri zabolevaniiakh legkikh u detei. M.: Medpraktika-M, 2013. [in Russian]
4. Irwin RS, Cynthia TF, Lewis SZ et al. Expert Cough Pane Overview of the Management of Cough: CHEST Guideline and Expert Panel Report. Chest 2014; 146 (4): 885–9.
5. Dicpinigaitis PV, Morice AH, Birring SS et al. Antitussive drugs – past, present, and future. Pharmacol Rev 2014; 66 (2): 468–512.
6. Chang AB, Glomb WB. Guidelines for evaluating chronic cough in pediatrics: ACCP evidence-based clinical practice guidelines. Chest 2006; 129: 260–83.
7. Morice AH, Millqvist E, Belvisi MG et al. Expert opinion on the cough hypersensitivity syndrome in respiratory medicine. Eur Respir J 2014; 44 (5): 1132–48.
8. Usta GB, Asilsoy S, Durmaz C. The assessment and management of chronic cough in children according to the British Thoracic Society guidelines: descriptive, prospective, clinical trial. Clin Respir J 2014; 8 (3): 330–7.
9. Morice AH, Fontana GA, Belvisi MG et al. ERS guidelines on the assessment of cough. Eur Respir J 2007; 29 (6): 1256–76.
10. Asthma Workgroup, Chinese Society, Respiratory, Diseases (CSRD), Chinese Medical, Association. The Chinese national guidelines on diagnosis and management of cough (December 2010). Chin Med J (Engl) 2011; 124 (20): 3207–19.
11. Birring SS, Kavanagh J, Lai K, Chang AB. Adult and paediatric cough guidelines: Ready for an overhaul? Pulm Pharmacol Ther 2015; 35: 137–44.
12. Gibson PG, Chang AB, Glasgow NJ et al. CICADA: Cough in Children and Adults: Diagnosis and Assessment. Australian cough guidelines summary statement. Med J Aust 2010; 192 (5): 265–71.
13. Gibson P, Wang G, McGarvey L et al. Treatment of Unexplained Chronic Cough: CHEST Guideline and Expert Panel Report. Chest 2016; 149 (1): 27–44.
14. Committee for the Japanese Respiratory Society Guidelines for Management of Cough, Kohno S, Ishida T et al. The Japanese Respiratory Society guidelines for management of cough. Respirology 2006; 11 (Suppl. 4): S135–86.
15. Krajnik M, Damps-Konstanska I, Gorska L, Jassem E. A portable automatic cough analyser in the ambulatory assessment of cough. Biomed Eng Online 2010; 9–17.
16. Spinou A, Birring SS. An update on measurement and monitoring of cough: what are the important study endpoints? J Thorac Dis 2014; 6 (S7): 728–S734.
17. Sinopal'nikov A.I., Kliachkina I.L. Kashel'. M.: Meditsinskoe informatsionnoe agentstvo, 2013. [in Russian]
18. Paniakina M.A., Ovchinnikov A.Iu., Korostelev S.A. Postinfektsionnyi kashel' – sovremennyi vzgliad na patogenez i vozmozhnosti terapii. Vestn. otorinolaringologii. 2013; 4: 78–81. [in Russian]
19. Grace M, Birrell MA, Dubuis E et al. Transient receptor potential channels mediate the tussive response to prostaglandin E2 and bradykinin. Thorax 2012; 67: 891–900.
20. Ohkura N, Fujimura M, Nakade Y et al. Heightened cough response to bronchoconstriction in cough variant asthma. Respirology 2012; 17 (6): 964–8.
21. Brendan JC, Chang AB, Bolser DC et al. Anatomy and Neurophysiology of Cough. Chest 2014; 146 (6): 1633–48.
22. Chung KF, McGarvey L, Mazzone SB. Chronic cough as a neuropathic disorder. Lancet Respir Med 2013; 1 (5): 414–22.
23. Udal'tsova E.V., Mel'nikova I.M., Mizernitskii Iu.L. Sovremennye aspekty patogeneza i diagnostiki kashlevogo sindroma u detei. Pul'monologiia detskogo vozrasta: problemy i resheniia. M., 2015. Vyp. 15; s. 41–57. [in Russian]
24. Pavlenko V.A., Mel'nikova I.M., Mizernitskii Iu.L. Kliniko-diagnosticheskie aspekty prognoza bronkhial'noi astmy u detei rannego vozrasta. Med. sovet. 2017; 9: 70–5. [in Russian]
25. Thach BT. Maturation of cough and other reflexes that protect the fetal and neonatal airway. Pulm Pharmacol Ther 2007; 20: 365–70.
26. Kantar A. Phenotypic presentation of chronic cough in children. J Thorac Dis 2017; 9 (4): 907–13.
27. Shields MD, Bush A, Everard ML et al. Recommendations for the assessment and management of cough in children. Thorax 2008; 63 (Suppl. III): iii 1–15.
28. Bondarchuk L.G., Levin A.B., Mizernitskii Iu.L. Osobennosti kliniki i trudnosti diagnostiki inorodnykh tel bronkhov u detei rannego vozrasta. 2-i Vsesoiuznyi kongress po bolezniam organov dykhaniia. Cheliabinsk, 1991; s. 234. [in Russian]
29. Morice A, Kardos P. Comprehensive evidence-based review on European antitussives. BMJ Open Respir Res 2016; 3 (1): e000137.
30. Mizernitskii Iu.L., Tsyplenkova S.E. Bronkhial'naia giperreaktivnost'. V kn.: Funktsional'nye sostoianiia i zabolevaniia v pediatrii. Pod red. Tsaregorodtseva A.D., Dlina V.V. M.: Overlei, 2011. Gl. 17; s. 332–53. [in Russian]
31. Rukuizha M.S., Nezabudkin S.N., Korostovtsev D.S., Nezabudkina A.S. Chlamydophila pneumoniae, Mycoplasma pneumoniae v formirovanii Th2 immunnogo otveta i nespetsificheskoi giperreaktivnosti bronkhov. Biulleten' meditsinskikh internet-konferentsii. 2013; 3 (2): 322–25. [in Russian]
32. Volkov K.S., Nisevich L.L., Namazova-Baranova L.S. i dr. Kashel' u detei: osobennosti diagnostiki i podkhody k terapii. Vopr. sovr. pediatrii. 2013, 12 (1): 112–6. [in Russian]
33. Pramono RX, Imtiaz SA, Rodriguez-Villegas EA. Cough-Based Algorithm for Automatic Diagnosis of Pertussis. PLoS One 2016; 11 (9): e0162128.
34. Gedik AH, Cakir E, Torun E et al. Evaluation of 563 children with chronic cough accompanied by a new clinical algorithm. Ital J Pediatr 2015; 41–73.
35. Karabel M, Kelekçi S, Karabel D, Gürkan MF. The evaluation of children with prolonged cough accompanied by American College of Chest Physicians guidelines. Clin Respir J 2014; 8 (2): 152–9.
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1 ФГБОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И.Пирогова» Минздрава России. 117997, Россия, Москва, ул. Островитянова, д. 1;
2 ФГБОУ ВО «Ярославский государственный медицинский университет» Минздрава России. 150000, Россия, Ярославль, ул. Революционная, д. 5
*yulmiz@mail.ru
1 N.I.Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation. 117997, Russian Federation, Moscow, ul. Ostrovitianova, d. 1;
2 Yaroslavl State Medical University of the Ministry of Health of the Russian Federation. 150000, Russian Federation, Yaroslavl, ul. Revoliutsionnaia, d. 5
*yulmiz@mail.ru