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Боль в спине: эпидемиология, этиология, лечение
Боль в спине: эпидемиология, этиология, лечение
Котова О.В., Акарачкова Е.С. Боль в спине: эпидемиология, этиология, лечение. Consilium Medicum. 2017; 19 (2.3. Неврология и Ревматология): 43–47. DOI: 10.26442/2075-1753_19.2.3.43-47
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Аннотация
В любое время 18% населения мира могут испытывать боль в нижней части спины, а 38% людей будут испытывать такую боль в течение 1 года. Боль в спине относится к числу очень дорогостоящих нарушений здоровья. После острого эпизода боли в нижней части спины 1/3 пациентов испытывают повторный эпизод, и примерно 1/2 из них обратятся за медицинской помощью. В статье представлены основные причины боли в спине и принципы терапии. На сегодняшний день приоритетным направлением ведения больного с болью в спине является максимально раннее купирование болевого синдрома. Для купирования острой боли в спине наиболее широкое применение получили нестероидные противовоспалительные препараты. С этой целью применяют как селективные ингибиторы циклооксигеназы 2-го типа, так и неселективные ингибиторы циклооксигеназы двух типов. Представлены преимущества назначения при боли в спине нимесулида (Найза) – представителя класса селективных ингибиторов циклооксигеназы-2.
Ключевые слова: боль в спине, эпидемиология, причины боли в спине, лечение, нестероидные противовоспалительные препараты, нимесулид (Найз).
Key words: back pain, epidemiology, causes of back pain, treatment, non-steroidal anti-inflammatory drugs, nimesulide (Nise).
Ключевые слова: боль в спине, эпидемиология, причины боли в спине, лечение, нестероидные противовоспалительные препараты, нимесулид (Найз).
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Key words: back pain, epidemiology, causes of back pain, treatment, non-steroidal anti-inflammatory drugs, nimesulide (Nise).
Полный текст
Список литературы
1. Hoy D, Bain C, Williams G et al. A systematic review of the global prevalence of low back pain. Arthritis Rheum 2012; 64 (6): 2028–37.
2. Vos T, Flaxman AD, Naghavi M et al. Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012; 380 (9859): 2163–96.
3. Machado GC, Maher CG, Ferreira PH et al. Can Recurrence After an Acute Episode of Low Back Pain Be Predicted? Phys Ther 2017; 97 (9): 889–95. DOI: 10.1093/ptj/pzx067
4. Hoy D, Brooks P, Blyth F, Buchbinder R. The Epidemiology of low back pain. Best Pract Res Clin Rheumatol 2010; 24 (6): 769–81. DOI: 10.1016/j.berh.2010.10.002
5. Hayden JA, Chou R, Hogg-Johnson S, Bombardier C. Systematic reviews of low back pain prognosis had variable methods and results: guidance for future prognosis reviews.
J Clin Epidemiol 2009; 62 (8): 781–96.
6. Wertli MM, Rasmussen-Barr E, Weiser S et al. The role of fear avoidance beliefs as a prognostic factor for outcome in patients with nonspecific low back pain: a systematic review. Spine 2014; 14 (5): 816–36.
7. Hall AM, Kamper SJ, Maher CG et al. Symptoms of depression and stress mediate the effect of pain on disability. Pain 2011; 152 (5): 1044–51.
8. Boer MJ, Struys MM, Versteegen GJ. Pain-related catastrophizing in pain patients and people with pain in the general population. Eur J Pain 2012; 16 (7): 1044–52.
9. Velasco Garrido M, Bittner C, Harth V, Preisser A. Health status and health-related quality of life of municipal waste collection workers - a cross-sectional survey. J Occup Med Toxicol 2015; 8: 10–22.
10. Dagenais S, Caro J, Haldeman S. A systematic review of low back pain cost of illness studies in the United States and internationally. Spine J 2008; 8 (1): 8–20.
11. Wieser S, Horisberger B, Schmidhauser S et al. Cost of low back pain in Switzerland in 2005. Eur J Health Econ 2011; 12 (5): 455–67.
12. Dagenais S, Caro J, Haldeman S. A systematic review of low back pain cost of illness studies in the United States and internationally. Spine J 2008; 8 (1): 8–20.
13. Котова О.В., Акарачкова Е.С., Данилов А.Б. Вопросы длительной терапии болевых синдромов. Рус. мед. журн. 2015; 23 (30): 16–8. / Kotova O.V., Akarachkova E.S., Danilov A.B. Voprosy dlitel'noi terapii bolevykh sindromov. Rus. med. zhurn. 2015; 23 (30): 16–8. [in Russian]
14. Левин О.С. Диагностика и лечение неврологических проявлений остеохондроза позвоночника. Consilium Medicum. 2004; 6 (8). / Levin O.S. Diagnostika i lechenie nevrologicheskikh proiavlenii osteokhondroza pozvonochnika. Consilium Medicum. 2004; 6 (8). [in Russian]
15. Справочник по формулированию клинического диагноза болезней нервной системы. Под ред. В.Н.Штока, О.С.Левина. М.: МИА, 2006. / Spravochnik po formulirovaniiu klinicheskogo diagnoza boleznei nervnoi sistemy. Pod red. V.N.Shtoka, O.S.Levina. M.: MIA, 2006. [in Russian]
16. Никифоров А.С., Авакян Г.Н., Мендель О.И. Неврологические осложнения остеохондроза позвоночника. М.: ГЭОТАР-Медиа, 2015. / Nikiforov A.S., Avakian G.N., Mendel' O.I. Nevrologicheskie oslozhneniia osteokhondroza pozvonochnika. M.: GEOTAR-Media, 2015. [in Russian]
17. Котова О.В. Острая боль в нижней части спины: не дать болезни затянуться. Фарматека. 2012; 14 (247): 60–4. / Kotova O.V. Ostraia bol' v nizhnei chasti spiny: ne dat' bolezni zatianut'sia. Farmateka. 2012; 14 (247): 60–4. [in Russian]
18. Прокопенко С.В., Исаева Н.В., Шанина Е.Г. Диагностика и лечение боли в спине у пациентов с коморбидной патологией. РМЖ. 2017; 24: 1593–8. / Prokopenko S.V., Isaeva N.V., Shanina E.G. Diagnostika i lechenie boli v spine u patsientov s komorbidnoi patologiei. RMZh. 2017; 24: 1593–8. [in Russian]
19. Левин О.С., Штульман Д.Р. Неврология: справочник практ. врача. Изд. 9-е, доп. и перераб. М.: Медпресс-информ, 2013; с. 183–200. / Levin O.S., Shtul'man D.R. Nevrologiia: spravochnik prakt. vracha. Izd. 9-e, dop. i pererab. M.: Medpress-inform, 2013; s. 183–200. [in Russian]
20. Подчуфарова Е.В., Яхно Н.Н. Боли в спине и конечностях. Болезни нервной системы. Руководство для врачей. М., 2005. / Podchufarova E.V., Iakhno N.N. Boli v spine i konechnostiakh. Bolezni nervnoi sistemy. Rukovodstvo dlia vrachei. M., 2005. [in Russian]
21. Каратеев А.Е., Яхно Н.Н., Лазебник Л.Б. и др. Применение нестероидных противовоспалительных препаратов. Клинические рекомендации. М.: ИМА-ПРЕСС, 2009. / Karateev A.E., Iakhno N.N., Lazebnik L.B. i dr. Primenenie nesteroidnykh protivovospalitel'nykh preparatov. Klinicheskie rekomendatsii. M.: IMA-PRESS, 2009. [in Russian]
22. Samad TA, Moore KA, Sapirstein A et al. Interleukin-1 beta-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity. Nature 2001; 410 (6827): 471–5.
23. Malmberg AB, Yaksh TL. Hyperalgesia mediated by spinal glutamate or substance P receptor blocked by spinal cyclooxygenase inhibition. Science 1992; 257 (5074): 1276–9.
24. Yamamoto T, Sakashita Y. COX-2 inhibitor prevents the development of hyperalgesia induced by intrathecal NMDA or AMPA. Neuroreport 1998; 9 (17): 3869–73.
25. Euchenhofer C, Maihófner C, Brune K et al. Differential effect of selective cyclooxygenase-2 (COX-2) inhibitor NS 398 and diclofenac on formalin-induced nociception in the rat. Neurosci Lett 1998; 248 (1): 25–8.
26. Telleria-Diaz A, Schmidt M, Kreusch S et al. Spinal antinociceptive effects of cyclooxygenase inhibition during inflammation: Involvement of prostaglandins and endocannabinoids. Pain 2010; 148 (1): 26–35.
27. Котова О.В., Акарачкова Е.С. Нимесулид: эффективность и безопасность применения. Consilium Medicum. 2016; 18 (2): 100–3. / Kotova O.V., Akarachkova E.S. Nimesulide: efficacy and safety. Consilium Medicum. 2016; 18 (2): 100–3. [in Russian]
28. Котова О.В. Боль в спине: предотвратить хронизацию. РМЖ. 2011; 30: 1872–3. / Kotova O.V. Bol' v spine: predotvratit' khronizatsiiu. RMZh. 2011; 30: 1872–3. [in Russian]
29. Pohjolainen T, Jekunen A, Autio L, Vuorela H. Treatment of acute low back pain with the COX-2-selective anti-inflammatory drug nimesulide: results of a randomized, double-blind comparative trial versus ibuprofen. Spine 2000; 25 (12): 1579–85.
2. Vos T, Flaxman AD, Naghavi M et al. Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012; 380 (9859): 2163–96.
3. Machado GC, Maher CG, Ferreira PH et al. Can Recurrence After an Acute Episode of Low Back Pain Be Predicted? Phys Ther 2017; 97 (9): 889–95. DOI: 10.1093/ptj/pzx067
4. Hoy D, Brooks P, Blyth F, Buchbinder R. The Epidemiology of low back pain. Best Pract Res Clin Rheumatol 2010; 24 (6): 769–81. DOI: 10.1016/j.berh.2010.10.002
5. Hayden JA, Chou R, Hogg-Johnson S, Bombardier C. Systematic reviews of low back pain prognosis had variable methods and results: guidance for future prognosis reviews.
J Clin Epidemiol 2009; 62 (8): 781–96.
6. Wertli MM, Rasmussen-Barr E, Weiser S et al. The role of fear avoidance beliefs as a prognostic factor for outcome in patients with nonspecific low back pain: a systematic review. Spine 2014; 14 (5): 816–36.
7. Hall AM, Kamper SJ, Maher CG et al. Symptoms of depression and stress mediate the effect of pain on disability. Pain 2011; 152 (5): 1044–51.
8. Boer MJ, Struys MM, Versteegen GJ. Pain-related catastrophizing in pain patients and people with pain in the general population. Eur J Pain 2012; 16 (7): 1044–52.
9. Velasco Garrido M, Bittner C, Harth V, Preisser A. Health status and health-related quality of life of municipal waste collection workers - a cross-sectional survey. J Occup Med Toxicol 2015; 8: 10–22.
10. Dagenais S, Caro J, Haldeman S. A systematic review of low back pain cost of illness studies in the United States and internationally. Spine J 2008; 8 (1): 8–20.
11. Wieser S, Horisberger B, Schmidhauser S et al. Cost of low back pain in Switzerland in 2005. Eur J Health Econ 2011; 12 (5): 455–67.
12. Dagenais S, Caro J, Haldeman S. A systematic review of low back pain cost of illness studies in the United States and internationally. Spine J 2008; 8 (1): 8–20.
13. Kotova O.V., Akarachkova E.S., Danilov A.B. Voprosy dlitel'noi terapii bolevykh sindromov. Rus. med. zhurn. 2015; 23 (30): 16–8. [in Russian]
14. Levin O.S. Diagnostika i lechenie nevrologicheskikh proiavlenii osteokhondroza pozvonochnika. Consilium Medicum. 2004; 6 (8). [in Russian]
15. Spravochnik po formulirovaniiu klinicheskogo diagnoza boleznei nervnoi sistemy. Pod red. V.N.Shtoka, O.S.Levina. M.: MIA, 2006. [in Russian]
16. Nikiforov A.S., Avakian G.N., Mendel' O.I. Nevrologicheskie oslozhneniia osteokhondroza pozvonochnika. M.: GEOTAR-Media, 2015. [in Russian]
17. Kotova O.V. Ostraia bol' v nizhnei chasti spiny: ne dat' bolezni zatianut'sia. Farmateka. 2012; 14 (247): 60–4. [in Russian]
18. Prokopenko S.V., Isaeva N.V., Shanina E.G. Diagnostika i lechenie boli v spine u patsientov s komorbidnoi patologiei. RMZh. 2017; 24: 1593–8. [in Russian]
19. Levin O.S., Shtul'man D.R. Nevrologiia: spravochnik prakt. vracha. Izd. 9-e, dop. i pererab. M.: Medpress-inform, 2013; s. 183–200. [in Russian]
20. Podchufarova E.V., Iakhno N.N. Boli v spine i konechnostiakh. Bolezni nervnoi sistemy. Rukovodstvo dlia vrachei. M., 2005. [in Russian]
21. Karateev A.E., Iakhno N.N., Lazebnik L.B. i dr. Primenenie nesteroidnykh protivovospalitel'nykh preparatov. Klinicheskie rekomendatsii. M.: IMA-PRESS, 2009. [in Russian]
22. Samad TA, Moore KA, Sapirstein A et al. Interleukin-1 beta-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity. Nature 2001; 410 (6827): 471–5.
23. Malmberg AB, Yaksh TL. Hyperalgesia mediated by spinal glutamate or substance P receptor blocked by spinal cyclooxygenase inhibition. Science 1992; 257 (5074): 1276–9.
24. Yamamoto T, Sakashita Y. COX-2 inhibitor prevents the development of hyperalgesia induced by intrathecal NMDA or AMPA. Neuroreport 1998; 9 (17): 3869–73.
25. Euchenhofer C, Maihófner C, Brune K et al. Differential effect of selective cyclooxygenase-2 (COX-2) inhibitor NS 398 and diclofenac on formalin-induced nociception in the rat. Neurosci Lett 1998; 248 (1): 25–8.
26. Telleria-Diaz A, Schmidt M, Kreusch S et al. Spinal antinociceptive effects of cyclooxygenase inhibition during inflammation: Involvement of prostaglandins and endocannabinoids. Pain 2010; 148 (1): 26–35.
27. Kotova O.V., Akarachkova E.S. Nimesulide: efficacy and safety. Consilium Medicum. 2016; 18 (2): 100–3. [in Russian]
28. Kotova O.V. Bol' v spine: predotvratit' khronizatsiiu. RMZh. 2011; 30: 1872–3. [in Russian]
29. Pohjolainen T, Jekunen A, Autio L, Vuorela H. Treatment of acute low back pain with the COX-2-selective anti-inflammatory drug nimesulide: results of a randomized, double-blind comparative trial versus ibuprofen. Spine 2000; 25 (12): 1579–85.
2. Vos T, Flaxman AD, Naghavi M et al. Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012; 380 (9859): 2163–96.
3. Machado GC, Maher CG, Ferreira PH et al. Can Recurrence After an Acute Episode of Low Back Pain Be Predicted? Phys Ther 2017; 97 (9): 889–95. DOI: 10.1093/ptj/pzx067
4. Hoy D, Brooks P, Blyth F, Buchbinder R. The Epidemiology of low back pain. Best Pract Res Clin Rheumatol 2010; 24 (6): 769–81. DOI: 10.1016/j.berh.2010.10.002
5. Hayden JA, Chou R, Hogg-Johnson S, Bombardier C. Systematic reviews of low back pain prognosis had variable methods and results: guidance for future prognosis reviews.
J Clin Epidemiol 2009; 62 (8): 781–96.
6. Wertli MM, Rasmussen-Barr E, Weiser S et al. The role of fear avoidance beliefs as a prognostic factor for outcome in patients with nonspecific low back pain: a systematic review. Spine 2014; 14 (5): 816–36.
7. Hall AM, Kamper SJ, Maher CG et al. Symptoms of depression and stress mediate the effect of pain on disability. Pain 2011; 152 (5): 1044–51.
8. Boer MJ, Struys MM, Versteegen GJ. Pain-related catastrophizing in pain patients and people with pain in the general population. Eur J Pain 2012; 16 (7): 1044–52.
9. Velasco Garrido M, Bittner C, Harth V, Preisser A. Health status and health-related quality of life of municipal waste collection workers - a cross-sectional survey. J Occup Med Toxicol 2015; 8: 10–22.
10. Dagenais S, Caro J, Haldeman S. A systematic review of low back pain cost of illness studies in the United States and internationally. Spine J 2008; 8 (1): 8–20.
11. Wieser S, Horisberger B, Schmidhauser S et al. Cost of low back pain in Switzerland in 2005. Eur J Health Econ 2011; 12 (5): 455–67.
12. Dagenais S, Caro J, Haldeman S. A systematic review of low back pain cost of illness studies in the United States and internationally. Spine J 2008; 8 (1): 8–20.
13. Котова О.В., Акарачкова Е.С., Данилов А.Б. Вопросы длительной терапии болевых синдромов. Рус. мед. журн. 2015; 23 (30): 16–8. / Kotova O.V., Akarachkova E.S., Danilov A.B. Voprosy dlitel'noi terapii bolevykh sindromov. Rus. med. zhurn. 2015; 23 (30): 16–8. [in Russian]
14. Левин О.С. Диагностика и лечение неврологических проявлений остеохондроза позвоночника. Consilium Medicum. 2004; 6 (8). / Levin O.S. Diagnostika i lechenie nevrologicheskikh proiavlenii osteokhondroza pozvonochnika. Consilium Medicum. 2004; 6 (8). [in Russian]
15. Справочник по формулированию клинического диагноза болезней нервной системы. Под ред. В.Н.Штока, О.С.Левина. М.: МИА, 2006. / Spravochnik po formulirovaniiu klinicheskogo diagnoza boleznei nervnoi sistemy. Pod red. V.N.Shtoka, O.S.Levina. M.: MIA, 2006. [in Russian]
16. Никифоров А.С., Авакян Г.Н., Мендель О.И. Неврологические осложнения остеохондроза позвоночника. М.: ГЭОТАР-Медиа, 2015. / Nikiforov A.S., Avakian G.N., Mendel' O.I. Nevrologicheskie oslozhneniia osteokhondroza pozvonochnika. M.: GEOTAR-Media, 2015. [in Russian]
17. Котова О.В. Острая боль в нижней части спины: не дать болезни затянуться. Фарматека. 2012; 14 (247): 60–4. / Kotova O.V. Ostraia bol' v nizhnei chasti spiny: ne dat' bolezni zatianut'sia. Farmateka. 2012; 14 (247): 60–4. [in Russian]
18. Прокопенко С.В., Исаева Н.В., Шанина Е.Г. Диагностика и лечение боли в спине у пациентов с коморбидной патологией. РМЖ. 2017; 24: 1593–8. / Prokopenko S.V., Isaeva N.V., Shanina E.G. Diagnostika i lechenie boli v spine u patsientov s komorbidnoi patologiei. RMZh. 2017; 24: 1593–8. [in Russian]
19. Левин О.С., Штульман Д.Р. Неврология: справочник практ. врача. Изд. 9-е, доп. и перераб. М.: Медпресс-информ, 2013; с. 183–200. / Levin O.S., Shtul'man D.R. Nevrologiia: spravochnik prakt. vracha. Izd. 9-e, dop. i pererab. M.: Medpress-inform, 2013; s. 183–200. [in Russian]
20. Подчуфарова Е.В., Яхно Н.Н. Боли в спине и конечностях. Болезни нервной системы. Руководство для врачей. М., 2005. / Podchufarova E.V., Iakhno N.N. Boli v spine i konechnostiakh. Bolezni nervnoi sistemy. Rukovodstvo dlia vrachei. M., 2005. [in Russian]
21. Каратеев А.Е., Яхно Н.Н., Лазебник Л.Б. и др. Применение нестероидных противовоспалительных препаратов. Клинические рекомендации. М.: ИМА-ПРЕСС, 2009. / Karateev A.E., Iakhno N.N., Lazebnik L.B. i dr. Primenenie nesteroidnykh protivovospalitel'nykh preparatov. Klinicheskie rekomendatsii. M.: IMA-PRESS, 2009. [in Russian]
22. Samad TA, Moore KA, Sapirstein A et al. Interleukin-1 beta-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity. Nature 2001; 410 (6827): 471–5.
23. Malmberg AB, Yaksh TL. Hyperalgesia mediated by spinal glutamate or substance P receptor blocked by spinal cyclooxygenase inhibition. Science 1992; 257 (5074): 1276–9.
24. Yamamoto T, Sakashita Y. COX-2 inhibitor prevents the development of hyperalgesia induced by intrathecal NMDA or AMPA. Neuroreport 1998; 9 (17): 3869–73.
25. Euchenhofer C, Maihófner C, Brune K et al. Differential effect of selective cyclooxygenase-2 (COX-2) inhibitor NS 398 and diclofenac on formalin-induced nociception in the rat. Neurosci Lett 1998; 248 (1): 25–8.
26. Telleria-Diaz A, Schmidt M, Kreusch S et al. Spinal antinociceptive effects of cyclooxygenase inhibition during inflammation: Involvement of prostaglandins and endocannabinoids. Pain 2010; 148 (1): 26–35.
27. Котова О.В., Акарачкова Е.С. Нимесулид: эффективность и безопасность применения. Consilium Medicum. 2016; 18 (2): 100–3. / Kotova O.V., Akarachkova E.S. Nimesulide: efficacy and safety. Consilium Medicum. 2016; 18 (2): 100–3. [in Russian]
28. Котова О.В. Боль в спине: предотвратить хронизацию. РМЖ. 2011; 30: 1872–3. / Kotova O.V. Bol' v spine: predotvratit' khronizatsiiu. RMZh. 2011; 30: 1872–3. [in Russian]
29. Pohjolainen T, Jekunen A, Autio L, Vuorela H. Treatment of acute low back pain with the COX-2-selective anti-inflammatory drug nimesulide: results of a randomized, double-blind comparative trial versus ibuprofen. Spine 2000; 25 (12): 1579–85.
________________________________________________
2. Vos T, Flaxman AD, Naghavi M et al. Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012; 380 (9859): 2163–96.
3. Machado GC, Maher CG, Ferreira PH et al. Can Recurrence After an Acute Episode of Low Back Pain Be Predicted? Phys Ther 2017; 97 (9): 889–95. DOI: 10.1093/ptj/pzx067
4. Hoy D, Brooks P, Blyth F, Buchbinder R. The Epidemiology of low back pain. Best Pract Res Clin Rheumatol 2010; 24 (6): 769–81. DOI: 10.1016/j.berh.2010.10.002
5. Hayden JA, Chou R, Hogg-Johnson S, Bombardier C. Systematic reviews of low back pain prognosis had variable methods and results: guidance for future prognosis reviews.
J Clin Epidemiol 2009; 62 (8): 781–96.
6. Wertli MM, Rasmussen-Barr E, Weiser S et al. The role of fear avoidance beliefs as a prognostic factor for outcome in patients with nonspecific low back pain: a systematic review. Spine 2014; 14 (5): 816–36.
7. Hall AM, Kamper SJ, Maher CG et al. Symptoms of depression and stress mediate the effect of pain on disability. Pain 2011; 152 (5): 1044–51.
8. Boer MJ, Struys MM, Versteegen GJ. Pain-related catastrophizing in pain patients and people with pain in the general population. Eur J Pain 2012; 16 (7): 1044–52.
9. Velasco Garrido M, Bittner C, Harth V, Preisser A. Health status and health-related quality of life of municipal waste collection workers - a cross-sectional survey. J Occup Med Toxicol 2015; 8: 10–22.
10. Dagenais S, Caro J, Haldeman S. A systematic review of low back pain cost of illness studies in the United States and internationally. Spine J 2008; 8 (1): 8–20.
11. Wieser S, Horisberger B, Schmidhauser S et al. Cost of low back pain in Switzerland in 2005. Eur J Health Econ 2011; 12 (5): 455–67.
12. Dagenais S, Caro J, Haldeman S. A systematic review of low back pain cost of illness studies in the United States and internationally. Spine J 2008; 8 (1): 8–20.
13. Kotova O.V., Akarachkova E.S., Danilov A.B. Voprosy dlitel'noi terapii bolevykh sindromov. Rus. med. zhurn. 2015; 23 (30): 16–8. [in Russian]
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Авторы
О.В.Котова*1, Е.С.Акарачкова1,2
1 ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М.Сеченова» Минздрава России. 119991, Россия, Москва, ул. Трубецкая, д. 8, стр. 2;
2 Международное общество «Стресс под контролем». 115573, Россия, Москва, ул. Мусы Джалиля, д. 40
*ol_kotova@mail.ru
1 I.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation. 119991, Russian Federation, Moscow, ul. Trubetskaia, d. 8, str. 2;
2 International Society “Stress under control”. 115573, Russian Federation, Moscow, ul. Musy Dzhalilya, d. 40
*ol_kotova@mail.ru
1 ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М.Сеченова» Минздрава России. 119991, Россия, Москва, ул. Трубецкая, д. 8, стр. 2;
2 Международное общество «Стресс под контролем». 115573, Россия, Москва, ул. Мусы Джалиля, д. 40
*ol_kotova@mail.ru
________________________________________________
1 I.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation. 119991, Russian Federation, Moscow, ul. Trubetskaia, d. 8, str. 2;
2 International Society “Stress under control”. 115573, Russian Federation, Moscow, ul. Musy Dzhalilya, d. 40
*ol_kotova@mail.ru
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