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Клиническая оценка влияния основных фитопрепаратов на эректильную функцию с позиции доказательной медицины
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Khadzhieva B.R. Clinical evaluation of the effect of basic phytopreparations on erectile function from the perspective of evidence-based medicine. Consilium Medicum. 2017; 19 (7): 86–88. DOI: 10.26442/2075-1753_19.7.86-88
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Ключевые слова: эректильная дисфункция, фитопрепараты, эврикоманоны, икариин, гинкго билоба, йохимбин.
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The use of phytopreparations for the purpose of correcting erectile dysfunction in men is quite widespread. We decided, from the perspective of evidence-based medicine, to assess their real potential and potential for use.
Key words: erectile dysfunction, phytopreparations, euricomannons, Icaryin, ginkgo biloba, yohimbine.
2. Udani JK, George AA, Musthapa M et al. Effects of a proprietary freeze-dried water extract of Eurycoma longifolia (Physta) and Polygonum minus on sexual performance and well-being in men: a randomized, double-Blind, placebo-controlled study [J]. Evid Based Complement Alternat Med 2014; 2014: 179529.
3. Tambi MI, Imran MK, Henkel RR. Standardised water-soluble extract of Eurycoma longifolia, Tongkat Ali, as testosterone booster for managing men with late-onset hypogonadism [J]. Andrologia 2012; 44 (Supp. 1): 226–30.
4. Thu HE, Mohamed IN et al. Eurycoma Longifolia as a potential adoptogen of male sexual health: a systematic review on clinical studies. Chin J Nat Med 2017; 15 (1): 71–80.
5. De Andrade E, de Mesquita AA, Claro JdeA et al. Study of the efficacy of Korean red ginseng in the treatment of erectile dysfunction. Asian J Androl 2007; 9: 241–4.
6. Jang DJ, Lee MS, Shin BC et al. Red ginseng for treating erectile dysfunction a systematic review. Br J Clin Pharmacol 2008; 66: 444–50.
7. Lee Y, Hin Y, Lim W et al. A ginsenoside-Rh1, a component of ginseng saponin, activates estrogen receptor in human breast carcinoma MCF-7cells. J Steroid Biochem Mol Biol 2003; 84: 463–8.
8. Shindel AW, Xin Z-C, Lin G et al. Erectogenic and neurotrophic effects of icariin, a purified extract of horny goat weed (Epimedium spp.) in vitro and in vivo. J Sex Med 2010; 7: 1518–28.
9. Dell’Agli M, Galli GV, Dal Cero E et al. Potent inhibition of human phosphodiesterase-5 by icariin derivatives. J Nat Prod 2008; 71: 1513–7.
10. Yang L, Lu D, Guo J et al. Icariin from Epimedium brevicornum Maxim promotes the biosynthesis of estrogen by aromatase (CYP19). J Ethnopharmacol 2013; 145: 715–21.
11. Murray M. The healing power of herbs. 2nd edition. Rocklin, CA: Prima Publishing; 1995: 147.
12. Koltermann A, Hartkorn A, Koch E et al. Ginkgo biloba extract EGb 761 increases endothelial nitric oxide production in vitro and in vivo. Cell Mol Life Sci 2007; 64: 1715–22.
13. Cohen AJ, Bartlik BD. Ginkgo biloba for drug-induced sexual dysfunction. Presented at the American Psychiatric Association Annual Meeting, San Diego, 1997.
14. Haller C, Kearney T, Bent S et al. Dietary supplement adverse events: Report of a one-year poison center surveillance project. J Med Toxicol 2008; 4: 84–92.
15. Ernst E, Pittler MH. Yohimbine for erectile dysfunction: A systematic review and meta-analysis of randomized clinical trials. J Urol 1998; 159: 433–6.
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1. Ayta I, Mckinlay J, Krane R. The likely worldwide increase in erectile dysfunction between 1995 and 2025 [J]. BJU Int 1999; 84 (1): 50–6.
2. Udani JK, George AA, Musthapa M et al. Effects of a proprietary freeze-dried water extract of Eurycoma longifolia (Physta) and Polygonum minus on sexual performance and well-being in men: a randomized, double-Blind, placebo-controlled study [J]. Evid Based Complement Alternat Med 2014; 2014: 179529.
3. Tambi MI, Imran MK, Henkel RR. Standardised water-soluble extract of Eurycoma longifolia, Tongkat Ali, as testosterone booster for managing men with late-onset hypogonadism [J]. Andrologia 2012; 44 (Supp. 1): 226–30.
4. Thu HE, Mohamed IN et al. Eurycoma Longifolia as a potential adoptogen of male sexual health: a systematic review on clinical studies. Chin J Nat Med 2017; 15 (1): 71–80.
5. De Andrade E, de Mesquita AA, Claro JdeA et al. Study of the efficacy of Korean red ginseng in the treatment of erectile dysfunction. Asian J Androl 2007; 9: 241–4.
6. Jang DJ, Lee MS, Shin BC et al. Red ginseng for treating erectile dysfunction a systematic review. Br J Clin Pharmacol 2008; 66: 444–50.
7. Lee Y, Hin Y, Lim W et al. A ginsenoside-Rh1, a component of ginseng saponin, activates estrogen receptor in human breast carcinoma MCF-7cells. J Steroid Biochem Mol Biol 2003; 84: 463–8.
8. Shindel AW, Xin Z-C, Lin G et al. Erectogenic and neurotrophic effects of icariin, a purified extract of horny goat weed (Epimedium spp.) in vitro and in vivo. J Sex Med 2010; 7: 1518–28.
9. Dell’Agli M, Galli GV, Dal Cero E et al. Potent inhibition of human phosphodiesterase-5 by icariin derivatives. J Nat Prod 2008; 71: 1513–7.
10. Yang L, Lu D, Guo J et al. Icariin from Epimedium brevicornum Maxim promotes the biosynthesis of estrogen by aromatase (CYP19). J Ethnopharmacol 2013; 145: 715–21.
11. Murray M. The healing power of herbs. 2nd edition. Rocklin, CA: Prima Publishing; 1995: 147.
12. Koltermann A, Hartkorn A, Koch E et al. Ginkgo biloba extract EGb 761 increases endothelial nitric oxide production in vitro and in vivo. Cell Mol Life Sci 2007; 64: 1715–22.
13. Cohen AJ, Bartlik BD. Ginkgo biloba for drug-induced sexual dysfunction. Presented at the American Psychiatric Association Annual Meeting, San Diego, 1997.
14. Haller C, Kearney T, Bent S et al. Dietary supplement adverse events: Report of a one-year poison center surveillance project. J Med Toxicol 2008; 4: 84–92.
15. Ernst E, Pittler MH. Yohimbine for erectile dysfunction: A systematic review and meta-analysis of randomized clinical trials. J Urol 1998; 159: 433–6.
ФГАОУ ВО «Первый Московский государственный университет им. И.М.Сеченова» Минздрава России. 119991, Россия, Москва, ул. Трубецкая, д. 8, стр. 2
bella1982@yandex.ru
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B.R.Khadzhieva
I.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation. 119991, Russian Federation, Moscow, ul. Trubetskaia, d. 8, str. 2
bella1982@yandex.ru