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Возможности хондроитина сульфата и глюкозамина в качестве адъювантной терапии хронической боли в спине
Возможности хондроитина сульфата и глюкозамина в качестве адъювантной терапии хронической боли в спине
Воробьева О.В. Возможности хондроитина сульфата и глюкозамина в качестве адъювантной терапии хронической боли в спине. Consilium Medicum. 2017; 19 (9): 59–64. DOI: 10.26442/2075-1753_19.9.59-64
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Аннотация
С возрастом дегенеративные изменения суставного аппарата позвоночника у большинства пациентов приобретают статус ведущей причины в рецидивировании боли в спине. Работа фокусируется на новейших исследованиях влияния хондроитина сульфата и глюкозамина на воспалительные процессы, ассоциированные с дегенеративными изменениями суставного аппарата позвоночника. Анализ данных клинических исследований эффективности комбинированного препарата АРТРА® при хронической боли в спине позволяет рассматривать его как перспективное лекарство для купирования и профилактики рецидивов боли в спине.
Ключевые слова: хроническая боль в спине, суставной аппарат позвоночника, хондроитин сульфат и глюкозамин, АРТРА.
Key words: chronic back pain, articular apparatus of the spine, chondroitin sulfate and glucosamine, ARTRA.
Ключевые слова: хроническая боль в спине, суставной аппарат позвоночника, хондроитин сульфат и глюкозамин, АРТРА.
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Key words: chronic back pain, articular apparatus of the spine, chondroitin sulfate and glucosamine, ARTRA.
Полный текст
Список литературы
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2. Dionne CE, Kunn KM, Croft PR. Does back pain prevalence really decrease with increasing age? A systematic review. Age Ageing 2006; 35: 229–34.
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4. Воробьева О.В., Вауличева А.Л. Хронизация боли в спине у мужчин трудоспособного возраста. Врач. 2010; 9: 47–50. / Vorobeva O.V., Vaulicheva A.L. Khronizatsiia boli v spine u muzhchin trudosposobnogo vozrasta. Vrach. 2010; 9: 47–50. [in Russian]
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13. Singh G, Alekseeva L, Alekseev V et al. Conbination treatment with glucosamine-chondroitin sulfate reduces pain, disability and NSAID consumption in patients with chronic low back pain: final results from a large, commute – based, pilot, open prospective study. Ann Rheum Dis 2014; 73 (Suppl. 2): 300.
14. Kocsis JJ, Harkaway S, Snyder R. Biological effects of the metabolites of dimethyl sulfoxide. Ann NY Acad Sci 1975; 243: 104–9.
15. Алексеева Л.И., Шарапова Е.П., Кашеварова Н.Г. и др. Применение АРТРА MСM ФОРТЕ у пациентов с остеоартрозом коленного сустава: результаты рандомизированного открытого сравнительного изучения эффективности и переносимости препарата. Терапевт. арх. 2015; 87 (12): 49–54. / Alekseeva L.I., Sharapova E.P., Kashevarova N.G. i dr. Primenenie ARTRA MSM FORTE u patsientov s osteoartrozom kolennogo sustava: rezul'taty randomizirovannogo otkrytogo sravnitel'nogo izucheniia effektivnosti i perenosimosti preparata. Terapevt. arkh. 2015; 87 (12): 49–54. [in Russian]
2. Dionne CE, Kunn KM, Croft PR. Does back pain prevalence really decrease with increasing age? A systematic review. Age Ageing 2006; 35: 229–34.
3. Leboeuf-Yde C, Nielsen J, Kyvik KO et al. Pain in the lumbar, thoracic or cervical regions: do age and gender matter? A population-based study of 34,902 Danish twins 20–71 years of age. BMC Musculoskelet Disord 2009; 20: 39.
4. Vorobeva O.V., Vaulicheva A.L. Khronizatsiia boli v spine u muzhchin trudosposobnogo vozrasta. Vrach. 2010; 9: 47–50. [in Russian]
5. Kolb E, Canjuga M, Bauer GF, Läubli T. Course of back pain across 5 years: a retrospective cohort study in the general population of Switzerland. Spine 2011; 36 (4): E268–73.
6. Clarke TC, Nahin RL, Barnes PM, Stussman BJ. National Center for Health Statistics Reports. Use of Complementary Health Approaches for Musculoskeletal Pain Disorders Among Adult. United States, 2012. https://www.cdc.gov/nchs/data/nhsr/nhsr098.pdf
7. Pearce RH, Grimmer BJ, Adams ME. Degeneration and the chemical composition of the human lumbar intervertebral disc. J Orthop Res 1987; 5 (2): 198–205.
8. Samartzis D, Karppinen J, Mok F et al. A population-based study of juvenile disc degeneration and its association with overweight and obesity, low back pain, and diminished functional status. J Bone Joint Surg Am 2011; 93 (7): 662–70.
9. Gandhi R, Woo KM, Zywiel MG, Rampersaud YR. Metabolic syndrome increases the prevalence of spine osteoarthritis. Orthop Surg 2014; 6 (1): 23–7.
10. Alekseeva L.I., Chichasova N.V., Mendel' O.I. Ratsional'nyi vybor bazisnoi terapii pri osteoartroze. Rezul'taty otkrytogo randomizirovannogo mnogotsentrovogo issledovaniia preparata ARTRA v Rossii. RMZh. 2005; 13 (24): 1637–40. [in Russian]
11. Souich P. Absorption, distribution and mechanism of action of SYSADOAS. Pharmacol Ther 2014; 142 (3): 362–74.
12. Raynauld JP, Pelletier JP, Abram F et al. Long-Term Effects of Glucosamine and Chondroitin Sulfate on the Progression of Structural Changes in Knee Osteoarthritis: Six-Year Followup Data From the Osteoarthritis Initiative. Ann Rheum Dis 2016; 75 (1): 37–44.
13. Singh G, Alekseeva L, Alekseev V et al. Conbination treatment with glucosamine-chondroitin sulfate reduces pain, disability and NSAID consumption in patients with chronic low back pain: final results from a large, commute – based, pilot, open prospective study. Ann Rheum Dis 2014; 73 (Suppl. 2): 300.
14. Kocsis JJ, Harkaway S, Snyder R. Biological effects of the metabolites of dimethyl sulfoxide. Ann NY Acad Sci 1975; 243: 104–9.
15. Alekseeva L.I., Sharapova E.P., Kashevarova N.G. i dr. Primenenie ARTRA MSM FORTE u patsientov s osteoartrozom kolennogo sustava: rezul'taty randomizirovannogo otkrytogo sravnitel'nogo izucheniia effektivnosti i perenosimosti preparata. Terapevt. arkh. 2015; 87 (12): 49–54. [in Russian]
2. Dionne CE, Kunn KM, Croft PR. Does back pain prevalence really decrease with increasing age? A systematic review. Age Ageing 2006; 35: 229–34.
3. Leboeuf-Yde C, Nielsen J, Kyvik KO et al. Pain in the lumbar, thoracic or cervical regions: do age and gender matter? A population-based study of 34,902 Danish twins 20–71 years of age. BMC Musculoskelet Disord 2009; 20: 39.
4. Воробьева О.В., Вауличева А.Л. Хронизация боли в спине у мужчин трудоспособного возраста. Врач. 2010; 9: 47–50. / Vorobeva O.V., Vaulicheva A.L. Khronizatsiia boli v spine u muzhchin trudosposobnogo vozrasta. Vrach. 2010; 9: 47–50. [in Russian]
5. Kolb E, Canjuga M, Bauer GF, Läubli T. Course of back pain across 5 years: a retrospective cohort study in the general population of Switzerland. Spine 2011; 36 (4): E268–73.
6. Clarke TC, Nahin RL, Barnes PM, Stussman BJ. National Center for Health Statistics Reports. Use of Complementary Health Approaches for Musculoskeletal Pain Disorders Among Adult. United States, 2012. https://www.cdc.gov/nchs/data/nhsr/nhsr098.pdf
7. Pearce RH, Grimmer BJ, Adams ME. Degeneration and the chemical composition of the human lumbar intervertebral disc. J Orthop Res 1987; 5 (2): 198–205.
8. Samartzis D, Karppinen J, Mok F et al. A population-based study of juvenile disc degeneration and its association with overweight and obesity, low back pain, and diminished functional status. J Bone Joint Surg Am 2011; 93 (7): 662–70.
9. Gandhi R, Woo KM, Zywiel MG, Rampersaud YR. Metabolic syndrome increases the prevalence of spine osteoarthritis. Orthop Surg 2014; 6 (1): 23–7.
10. Алексеева Л.И., Чичасова Н.В., Мендель О.И. Рациональный выбор базисной терапии при остеоартрозе. Результаты открытого рандомизированного многоцентрового исследования препарата АРТРА в России. РМЖ. 2005; 13 (24): 1637–40. / Alekseeva L.I., Chichasova N.V., Mendel' O.I. Ratsional'nyi vybor bazisnoi terapii pri osteoartroze. Rezul'taty otkrytogo randomizirovannogo mnogotsentrovogo issledovaniia preparata ARTRA v Rossii. RMZh. 2005; 13 (24): 1637–40. [in Russian]
11. Souich P. Absorption, distribution and mechanism of action of SYSADOAS. Pharmacol Ther 2014; 142 (3): 362–74.
12. Raynauld JP, Pelletier JP, Abram F et al. Long-Term Effects of Glucosamine and Chondroitin Sulfate on the Progression of Structural Changes in Knee Osteoarthritis: Six-Year Followup Data From the Osteoarthritis Initiative. Ann Rheum Dis 2016; 75 (1): 37–44.
13. Singh G, Alekseeva L, Alekseev V et al. Conbination treatment with glucosamine-chondroitin sulfate reduces pain, disability and NSAID consumption in patients with chronic low back pain: final results from a large, commute – based, pilot, open prospective study. Ann Rheum Dis 2014; 73 (Suppl. 2): 300.
14. Kocsis JJ, Harkaway S, Snyder R. Biological effects of the metabolites of dimethyl sulfoxide. Ann NY Acad Sci 1975; 243: 104–9.
15. Алексеева Л.И., Шарапова Е.П., Кашеварова Н.Г. и др. Применение АРТРА MСM ФОРТЕ у пациентов с остеоартрозом коленного сустава: результаты рандомизированного открытого сравнительного изучения эффективности и переносимости препарата. Терапевт. арх. 2015; 87 (12): 49–54. / Alekseeva L.I., Sharapova E.P., Kashevarova N.G. i dr. Primenenie ARTRA MSM FORTE u patsientov s osteoartrozom kolennogo sustava: rezul'taty randomizirovannogo otkrytogo sravnitel'nogo izucheniia effektivnosti i perenosimosti preparata. Terapevt. arkh. 2015; 87 (12): 49–54. [in Russian]
________________________________________________
2. Dionne CE, Kunn KM, Croft PR. Does back pain prevalence really decrease with increasing age? A systematic review. Age Ageing 2006; 35: 229–34.
3. Leboeuf-Yde C, Nielsen J, Kyvik KO et al. Pain in the lumbar, thoracic or cervical regions: do age and gender matter? A population-based study of 34,902 Danish twins 20–71 years of age. BMC Musculoskelet Disord 2009; 20: 39.
4. Vorobeva O.V., Vaulicheva A.L. Khronizatsiia boli v spine u muzhchin trudosposobnogo vozrasta. Vrach. 2010; 9: 47–50. [in Russian]
5. Kolb E, Canjuga M, Bauer GF, Läubli T. Course of back pain across 5 years: a retrospective cohort study in the general population of Switzerland. Spine 2011; 36 (4): E268–73.
6. Clarke TC, Nahin RL, Barnes PM, Stussman BJ. National Center for Health Statistics Reports. Use of Complementary Health Approaches for Musculoskeletal Pain Disorders Among Adult. United States, 2012. https://www.cdc.gov/nchs/data/nhsr/nhsr098.pdf
7. Pearce RH, Grimmer BJ, Adams ME. Degeneration and the chemical composition of the human lumbar intervertebral disc. J Orthop Res 1987; 5 (2): 198–205.
8. Samartzis D, Karppinen J, Mok F et al. A population-based study of juvenile disc degeneration and its association with overweight and obesity, low back pain, and diminished functional status. J Bone Joint Surg Am 2011; 93 (7): 662–70.
9. Gandhi R, Woo KM, Zywiel MG, Rampersaud YR. Metabolic syndrome increases the prevalence of spine osteoarthritis. Orthop Surg 2014; 6 (1): 23–7.
10. Alekseeva L.I., Chichasova N.V., Mendel' O.I. Ratsional'nyi vybor bazisnoi terapii pri osteoartroze. Rezul'taty otkrytogo randomizirovannogo mnogotsentrovogo issledovaniia preparata ARTRA v Rossii. RMZh. 2005; 13 (24): 1637–40. [in Russian]
11. Souich P. Absorption, distribution and mechanism of action of SYSADOAS. Pharmacol Ther 2014; 142 (3): 362–74.
12. Raynauld JP, Pelletier JP, Abram F et al. Long-Term Effects of Glucosamine and Chondroitin Sulfate on the Progression of Structural Changes in Knee Osteoarthritis: Six-Year Followup Data From the Osteoarthritis Initiative. Ann Rheum Dis 2016; 75 (1): 37–44.
13. Singh G, Alekseeva L, Alekseev V et al. Conbination treatment with glucosamine-chondroitin sulfate reduces pain, disability and NSAID consumption in patients with chronic low back pain: final results from a large, commute – based, pilot, open prospective study. Ann Rheum Dis 2014; 73 (Suppl. 2): 300.
14. Kocsis JJ, Harkaway S, Snyder R. Biological effects of the metabolites of dimethyl sulfoxide. Ann NY Acad Sci 1975; 243: 104–9.
15. Alekseeva L.I., Sharapova E.P., Kashevarova N.G. i dr. Primenenie ARTRA MSM FORTE u patsientov s osteoartrozom kolennogo sustava: rezul'taty randomizirovannogo otkrytogo sravnitel'nogo izucheniia effektivnosti i perenosimosti preparata. Terapevt. arkh. 2015; 87 (12): 49–54. [in Russian]
Авторы
О.В.Воробьева
ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М.Сеченова» Минздрава России. 119991, Россия, Москва, ул. Трубецкая, д. 8, стр. 2
ovvorobeva@mail.ru
I.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation. 119991, Russian Federation, Moscow, ul. Trubetskaia, d. 8, str. 2
ovvorobeva@mail.ru
ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М.Сеченова» Минздрава России. 119991, Россия, Москва, ул. Трубецкая, д. 8, стр. 2
ovvorobeva@mail.ru
________________________________________________
I.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation. 119991, Russian Federation, Moscow, ul. Trubetskaia, d. 8, str. 2
ovvorobeva@mail.ru
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