Синдром Персонейджа–Тернера – редкое неврологическое заболевание неопределенной этиологии, имеющее характерную клиническую картину: выраженный болевой синдром в дебюте заболевания, дальнейший регресс болевой симптоматики, последующее развитие слабости мускулатуры лопаточного пояса. Данная клиническая картина является ключом к диагностике этого заболевания. Преимущество постановки правильного диагноза определяет оптимальную тактику лечения, позволяет избежать назначения дополнительных методов обследования. В статье представлено описание двух клинических случаев острой идиопатической невралгической амиотрофии (синдром Персонейджа–Тернера). Обсуждаются вопросы клинической картины, дифференциальной диагностики и течения данного заболевания.
Ключевые слова: синдром Персонейджа–Тернера, невралгическая амиотрофия, крыловидное положение лопатки.
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The Parsonage–Turner syndrome, relatively rare disease of uncertain etiology, which has a characteristic clinical picture: severe pain syndrome in the onset of the disease, further regression of pain symptoms, and subsequent development of weakness in the musculature of the scapula. This clinical picture is the key to diagnosing this disease. The advantage of setting the right diagnosis determines the optimal treatment tactics, it allows to avoid the appointment of additional survey methods. The article describes two clinical cases of idiopathic neural amyotrophy (Parsonage–Turner syndrome). Questions of the clinical picture, differential diagnosis and course of the disease are discussed.
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2. Bramwell E, Struthers JW. Paralysis of the serratus magnus and lower part of the trapezius muscles. Rev Neurol Psychiatr 1903; 1: 717–30.
3. Wyburn-Mason R. Brachial neuritis occurring in epidemic form. Lancet 1941; 1: 662–3.
4. Burnard ED, Fox TG. Multiple neuritis of shoulder girdle: report of nine cases occurring in second New Zealand expeditionary force. NZ Med J 1942: 41.
5. Spillane JD. Localised neuritis of the shoulder girdle: a report of 46 patients in the MEF. Lancet 1943; 2: 594–5.
8. Miller JD, Pruitt S, McDonald TJ. Acute brachial plexus neuritis: an uncommon cause of shoulder pain. Am Family Physician 2000; 62 (9): 2067–72.
9. Tsairis P, Dyck PJ, Mulder DW. Natural history of brachial plexus neuropathy. Report on 99 patients. Arch Neurol 1972; 27 (2): 109–17. [PubMed]
10. Tonali P, Uncini A, Di Pasqua PG. So-called neuralgic amyotrophy: clinical features and long term follow-up. Ital J Neurol Sci 1983; 4 (4): 431–7. [PubMed]
11. Van Alfen N, van Engelen BGM. The clinical spectrum of neuralgic amyotrophy in 246 cases. Brain 2006; 129 (Pt 2): 438–50. [PubMed]
13. Suarez GA, Giannini C, Bosch EP et al. Immune brachial plexus neuropathy: suggestive evidence for an inflammatory-immune pathogenesis. Neurology 1996; 46 (2): 559–61. [PubMed]
14. Bardos V, Somodska V. Epidemiologic study of a brachial plexus neuritis outbreak in northeast Czechoslovakia. World Neurol 1961; 2: 973–9. [PubMed]
15. Seror P, Harbach S. Parsonage–Turner syndrome after cytomegalovirus infection. Presse Med 1990; 19 (11): 527–8. [PubMed]
16. Botella MS, Garcia M, Cuadrado JM, Martin R. Parsonage–Turner syndrome in positive HIV patients. Rev Neurol 1997; 25 (137): 143. [Letter] [PubMed].
17. Jiguet M, Troussier B, Phelip X. Parsonage and Turner syndrome. Apropos of a case, with demonstration of Borrelia burgdorferi infection. Rev Rhum Mal Osteoartic 1991; 58 (5): 409–11. [PubMed]
18. Kuhlenbäumer G, Hannibal MC, Nelis E et al. Mutations in SEPT9 cause hereditary neuralgic amyotrophy. Nat Genet 2005; 37 (10): 1044–6. [PubMed]
19. Auge WK, Velazquez PA. Parsonage–Turner syndrome in the Native American Indian. J Shoulder Elbow Surg 2000; 9 (2): 99–103. [PubMed]
27. Favero KJ, Hawkins RH, Jones MW. Neuralgic amyotrophy. J Bone Jt Surg Br 1987; 69 (2): 195–8. [PubMed]
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1. Feinberg J. Fall von Erb-Klumpke scher: lahmung nach influenza. Centralbl 1897; 16: 588–637.
2. Bramwell E, Struthers JW. Paralysis of the serratus magnus and lower part of the trapezius muscles. Rev Neurol Psychiatr 1903; 1: 717–30.
3. Wyburn-Mason R. Brachial neuritis occurring in epidemic form. Lancet 1941; 1: 662–3.
4. Burnard ED, Fox TG. Multiple neuritis of shoulder girdle: report of nine cases occurring in second New Zealand expeditionary force. NZ Med J 1942: 41.
5. Spillane JD. Localised neuritis of the shoulder girdle: a report of 46 patients in the MEF. Lancet 1943; 2: 594–5.
8. Miller JD, Pruitt S, McDonald TJ. Acute brachial plexus neuritis: an uncommon cause of shoulder pain. Am Family Physician 2000; 62 (9): 2067–72.
9. Tsairis P, Dyck PJ, Mulder DW. Natural history of brachial plexus neuropathy. Report on 99 patients. Arch Neurol 1972; 27 (2): 109–17. [PubMed]
10. Tonali P, Uncini A, Di Pasqua PG. So-called neuralgic amyotrophy: clinical features and long term follow-up. Ital J Neurol Sci 1983; 4 (4): 431–7. [PubMed]
11. Van Alfen N, van Engelen BGM. The clinical spectrum of neuralgic amyotrophy in 246 cases. Brain 2006; 129 (Pt 2): 438–50. [PubMed]
13. Suarez GA, Giannini C, Bosch EP et al. Immune brachial plexus neuropathy: suggestive evidence for an inflammatory-immune pathogenesis. Neurology 1996; 46 (2): 559–61. [PubMed]
14. Bardos V, Somodska V. Epidemiologic study of a brachial plexus neuritis outbreak in northeast Czechoslovakia. World Neurol 1961; 2: 973–9. [PubMed]
15. Seror P, Harbach S. Parsonage–Turner syndrome after cytomegalovirus infection. Presse Med 1990; 19 (11): 527–8. [PubMed]
16. Botella MS, Garcia M, Cuadrado JM, Martin R. Parsonage–Turner syndrome in positive HIV patients. Rev Neurol 1997; 25 (137): 143. [Letter] [PubMed].
17. Jiguet M, Troussier B, Phelip X. Parsonage and Turner syndrome. Apropos of a case, with demonstration of Borrelia burgdorferi infection. Rev Rhum Mal Osteoartic 1991; 58 (5): 409–11. [PubMed]
18. Kuhlenbäumer G, Hannibal MC, Nelis E et al. Mutations in SEPT9 cause hereditary neuralgic amyotrophy. Nat Genet 2005; 37 (10): 1044–6. [PubMed]
19. Auge WK, Velazquez PA. Parsonage–Turner syndrome in the Native American Indian. J Shoulder Elbow Surg 2000; 9 (2): 99–103. [PubMed]
1 ФГБОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И.Пирогова» Минздрава России. 117997, Россия, Москва, ул. Островитянова, д. 1
2 ГБУЗ «Городская клиническая больница №31» Департамента здравоохранения г. Москвы. 119415, Россия, Москва, ул. Лобачевского, д. 42
1 N.I.Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation. 117997, Russian Federation, Moscow, ul. Ostrovitianova, d. 1
2 City Clinical Hospital №31 of the Department of Health of Moscow. 119415, Russian Federation, Moscow, ul. Lobachevskogo, d. 42