Мини-гастрошунтирование: новая операция выбора метаболической хирургии при сахарном диабете 2-го типа?
Мини-гастрошунтирование: новая операция выбора метаболической хирургии при сахарном диабете 2-го типа?
Скляник И.А., Кармадонов А.В., Шестакова М.В. Мини-гастрошунтирование: новая операция выбора метаболической хирургии при сахарном диабете 2-го типа? Consilium Medicum. 2019; 21 (4): 56–58. DOI: 10.26442/20751753.2019.4.190324
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Sklyanik I.A., Karmadonov A.V., Shestakova M.V. Mini-gastric bypass: is it a new operation of choice in metabolic surgery in diabetes mellitus type 2? Consilium Medicum. 2019; 21 (4): 56–58. DOI: 10.26442/20751753.2019.4.190324
Мини-гастрошунтирование: новая операция выбора метаболической хирургии при сахарном диабете 2-го типа?
Скляник И.А., Кармадонов А.В., Шестакова М.В. Мини-гастрошунтирование: новая операция выбора метаболической хирургии при сахарном диабете 2-го типа? Consilium Medicum. 2019; 21 (4): 56–58. DOI: 10.26442/20751753.2019.4.190324
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Sklyanik I.A., Karmadonov A.V., Shestakova M.V. Mini-gastric bypass: is it a new operation of choice in metabolic surgery in diabetes mellitus type 2? Consilium Medicum. 2019; 21 (4): 56–58. DOI: 10.26442/20751753.2019.4.190324
Актуальность. Масштаб распространения сахарного диабета 2-го типа (СД 2) и ожирения носит характер пандемии. Медикаментозная терапия этих состояний достигла огромных успехов, однако все еще остаются пациенты, подверженные осложнениям, вызванным данными заболеваниями. Известен положительный эффект метаболической хирургии у пациентов с СД 2 и ожирением. В обзоре рассматривается влияние мини-гастрошунтирования (МГШ) на течение СД 2 и его возможную ремиссию. Материалы и методы. Проведен поиск литературы по базам данных Medline, Scopus, Web of Sciences, РИНЦ, и использованы следующие ключевые слова: mini gastric bypass, single anastomosis gastric bypass, omega loop gastric bypass, loop gastric bypass, MGB, LMGB, мини-гастрошунтирование, гастрошунтирование с одним анастомозом. Языки поиска: английский и русский. Поиск проведен по публикациям, опубликованным с 2001 по 2019 г. Результаты. Показано значительное улучшение течения СД 2 после проведения МГШ. В 75–90% случаев удается достичь ремиссии СД 2. При этом результаты не отличаются, а в некоторых случаях превосходят классическое гастрошунтирование и значительно превосходят рукавную гастропластику. Не выявлено повышенного риска развития осложнений как в раннем, так и в позднем послеоперационных периодах. Заключение. МГШ представляется эффективной бариатрической операцией и может являться операцией выбора при наличии у пациента ожирения с СД 2. Тем не менее целесообразно проведение дальнейших проспективных рандомизированных контролируемых исследований для определения дополнительных метаболических преимуществ МГШ.
Ключевые слова: мини-гастрошунтирование, сахарный диабет 2-го типа, ожирение, метаболическая хирургия.
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Relevance. The prevalence of diabetes mellitus type 2 (DM2) and obesity takes a pandemic form. Substantial progress had been made in pharmacotherapy for these disorders but there still are patients who develop complications caused by these disorders. A positive effect of metabolic surgery in patients with DM2 and obesity is well known. The review discusses the influence of mini-gastric bypass (MGP) on DM2 course and the possibility of DM2 remission. Materials and methods. A literature search was performed in Medline, Scopus, Web of Sciences, and RSCI databases with the use of key words: mini gastric bypass, single anastomosis gastric bypass, omega loop gastric bypass, loop gastric bypass, MGB, LMGB, мини-гастрошунтирование, гастрошунтирование с одним анастомозом. The search was performed in English and Russian. The search was performed for publications over the years 2001–2019. Results. A considerable improvement in DM2 course after MGP was shown. In 75–90% of cases DM2 remission could be achieved. The acquired results were not different and in some cases were better than those of traditional gastric bypass and were much better than results of sleeve gastrectomy. An increased risk of complications development was found neither in early nor in late postoperative period. Conclusion. MGB appears an effective bariatric operation and can be an operation of choice in patients with DM2 and obesity. Nevertheless it is reasonable to perform more prospective randomized controlled trials to determine additional metabolic advantages of MGB.
1. International Diabetes Federation. IDF Diabetes Atlas. 8th ed. Brussels: IDF, 2017; p. 148.
2. WHO. Obesity and overweight. Key facts [Internet]. 2019. https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight
3. Дедов И.И., Шестакова М.В., Майоров А.Ю. и др. Алгоритмы специализированной медицинской помощи больным сахарным диабетом. Под ред. И.И.Дедова, М.В.Шестаковой, А.Ю.Майорова. Вып. 8. Сахарный диабет. 2017; 20 (1S): 1–121. DOI: 10.14341/DM20171S8
[Dedov I.I., Shestakova M.V., Maiorov A.Iu. i dr. Algoritmy spetsializirovannoi meditsinskoi pomoshchi bol'nym sakharnym diabetom. Pod red. I.I.Dedova, M.V.Shestakovoi, A.Iu.Maiorova. Vyp. 8. Sakharnyi diabet. 2017; 20 (1S): 1–121. DOI: 10.14341/DM20171S8 (in Russian).]
4. Rutledge R. The mini-gastric bypass: experience with the first 1,274 cases. Obes Surg 2001; 11 (3): 276–80. DOI: 10.1381/096089201321336584
5. Park HJ, Hong SS, Hwang J, Hur KY. Mini-gastric bypass to control morbid obesity and diabetes mellitus: what radiologists need to know. Korean J Radiol 16 (2): 325–33. DOI: 10.3348/kjr.2015.16.2.325
6. Rutledge R, Walsh TR. Continued excellent results with the mini-gastric bypass: six-year study in 2,410 patients. Obes Surg 2005; 15 (9): 1304–8. DOI: 10.1381/096089205774512663
7. Chakhtoura G, Zinzindohoué F, Ghanem Y et al. Primary results of laparoscopic mini-gastric bypass in a French obesity-surgery specialized university hospital. Obes Surg 2008; 18 (9): 1130–3. DOI: 10.1007/s11695-008-9594-8
8. Hussain A, EL-Hasani S. Short- and Mid-term Outcomes of 527 One Anastomosis Gastric Bypass/Mini-Gastric Bypass (OAGB/MGB) Operations: Retrospective Study. Obes Surg [Internet] 2019; 29 (1): 262–7. DOI: 10.1007/s11695-018-3516-1
9. Guenzi M, Arman G, Rau C et al. Remission of type 2 diabetes after omega loop gastric bypass for morbid obesity. Surg Endosc 2015; 29 (9): 2669–74. DOI: 10.1007/s00464-014-3987-7
10. Musella M, Susa A, Greco F et al. The laparoscopic mini-gastric bypass: the Italian experience: outcomes from 974 consecutive cases in a multicenter review. Surg Endosc 2014; 28 (1): 156–63. DOI: 10.1007/s00464-013-3141-y
11. Carbajo MA, Luque-de-León E, Jiménez JM et al. Laparoscopic One-Anastomosis Gastric Bypass: Technique, Results, and Long-Term Follow-Up in 1200 Patients. Obes Surg 2017; 27 (5): 1153–67. DOI: 10.1007/s11695-016-2428-1
12. Taha O, Abdelaal M, Abozeid M et al. Outcomes of Omega Loop Gastric Bypass, 6-Years Experience of 1520 Cases. Obes Surg 2017; 27 (8): 1952–60. DOI: 10.1007/s11695-017-2623-8
13. Lee W-J, Yu P-J, Wang W et al. Laparoscopic Roux-en-Y versus mini-gastric bypass for the treatment of morbid obesity: a prospective randomized controlled clinical trial. Ann Surg 2005; 242 (1): 20–8.
14. Lee W-J, Ser K-H, Lee Y-C et al. Laparoscopic Roux-en-Y vs. mini-gastric bypass for the treatment of morbid obesity: a 10-year experience. Obes Surg 2012; 22 (12): 1827–34. DOI: 10.1007/s11695-012-0726-9
15. Quan Y, Huang A, Ye M et al. Efficacy of Laparoscopic Mini Gastric Bypass for Obesity and Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis. Gastroenterol Res Pract 2015; 2015: 152852. DOI: 10.1155/2015/152852
16. Wang F-G, Yan W-M, Yan M, Song M-M. Outcomes of Mini vs Roux-en-Y gastric bypass: A meta-analysis and systematic review. Int J Surg 2018; 56: 7–14. DOI: 10.1016/j.ijsu.2018.05.009
17. Robert M, Espalieu P, Pelascini E et al. Efficacy and safety of one anastomosis gastric bypass versus Roux-en-Y gastric bypass for obesity (YOMEGA): a multicentre, randomised, open-label, non-inferiority trial. Lancet 2019; 6736 (19): 1–11. DOI: 10.1016/S0140-6736(19)30475-1
18. Lee W-J, Chong K, Lin Y-H et al. Laparoscopic sleeve gastrectomy versus single anastomosis (mini-) gastric bypass for the treatment of type 2 diabetes mellitus: 5-year results of a randomized trial and study of incretin effect. Obes Surg 2014; 24 (9): 1552–62. DOI: 10.1007/s11695-014-1344-5
19. Kular KS, Manchanda N, Rutledge R. Analysis of the five-year outcomes of sleeve gastrectomy and mini gastric bypass: a report from the Indian sub-continent. Obes Surg 2014; 24 (10): 1724–8. DOI: 10.1007/s11695-014-1264-4
20. Celik A, Pouwels S, Karaca FC et al. Time to Glycemic Control – an Observational Study of 3 Different Operations. Obes Surg 2017; 27 (3): 694–702. DOI: 10.1007/s11695-016-2344-4
21. Kular KS, Manchanda N, Cheema GK. Seven Years of Mini-Gastric Bypass in Type II Diabetes Patients with a Body Mass Index <35 kg/m(2). Obes Surg 2016; 26 (7): 1457–62. DOI: 10.1007/s11695-015-1941-y
22. Mahawar KK, Kumar P, Carr WR et al. Current status of mini-gastric bypass. J Minim Access Surg 12 (4): 305–10. DOI: 10.4103/0972-9941.181352
23. Noun R, Skaff J, Riachi E et al. One thousand consecutive mini-gastric bypass: short-and long-term outcome. Obes Surg 2012; 22 (5): 697–703. DOI: 10.1007/s11695-012-0618-z
24. Kular KS, Manchanda N, Rutledge R. A 6-year experience with 1,054 mini-gastric bypasses-first study from Indian subcontinent. Obes Surg 2014; 24 (9): 1430–5. DOI: 10.1007/s11695-014-1220-3
25. Peraglie C. Laparoscopic mini-gastric bypass in patients age 60 and older. Surg Endosc 2016; 30 (1): 38–43. DOI: 10.1007/s00464-015-4157-2
26. Bruzzi M, Chevallier J-M, Czernichow S. One-Anastomosis Gastric Bypass: Why Biliary Reflux Remains Controversial? Obes Surg 2017; 27 (2): 545–7. DOI: 10.1007/s11695-016-2480-x
27. Guirat A, Addossari HM. One Anastomosis Gastric Bypass and Risk of Cancer. Obes Surg 2018; 28 (5): 1441–4. DOI: 10.1007/s11695-018-3156-5
28. Keleidari B, Mahmoudieh M, Davarpanah Jazi AH et al. Comparison of the Bile Reflux Frequency in One Anastomosis Gastric Bypass and Roux-en-Y Gastric Bypass: a Cohort Study. Obes Surg 2019. DOI: 10.1007/s11695-018-03683-6
29. Ahuja A, Tantia O, Goyal G et al. MGB-OAGB: Effect of Biliopancreatic Limb Length on Nutritional Deficiency, Weight Loss, and Comorbidity Resolution. Obes Surg 2018; 28 (11): 3439–45. DOI: 10.1007/s11695-018-3405-7
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1. International Diabetes Federation. IDF Diabetes Atlas. 8th ed. Brussels: IDF, 2017; p. 148.
2. WHO. Obesity and overweight. Key facts [Internet]. 2019. https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight
3. Dedov I.I., Shestakova M.V., Maiorov A.Iu. i dr. Algoritmy spetsializirovannoi meditsinskoi pomoshchi bol'nym sakharnym diabetom. Pod red. I.I.Dedova, M.V.Shestakovoi, A.Iu.Maiorova. Vyp. 8. Sakharnyi diabet. 2017; 20 (1S): 1–121. DOI: 10.14341/DM20171S8 (in Russian).
4. Rutledge R. The mini-gastric bypass: experience with the first 1,274 cases. Obes Surg 2001; 11 (3): 276–80. DOI: 10.1381/096089201321336584
5. Park HJ, Hong SS, Hwang J, Hur KY. Mini-gastric bypass to control morbid obesity and diabetes mellitus: what radiologists need to know. Korean J Radiol 16 (2): 325–33. DOI: 10.3348/kjr.2015.16.2.325
6. Rutledge R, Walsh TR. Continued excellent results with the mini-gastric bypass: six-year study in 2,410 patients. Obes Surg 2005; 15 (9): 1304–8. DOI: 10.1381/096089205774512663
7. Chakhtoura G, Zinzindohoué F, Ghanem Y et al. Primary results of laparoscopic mini-gastric bypass in a French obesity-surgery specialized university hospital. Obes Surg 2008; 18 (9): 1130–3. DOI: 10.1007/s11695-008-9594-8
8. Hussain A, EL-Hasani S. Short- and Mid-term Outcomes of 527 One Anastomosis Gastric Bypass/Mini-Gastric Bypass (OAGB/MGB) Operations: Retrospective Study. Obes Surg [Internet] 2019; 29 (1): 262–7. DOI: 10.1007/s11695-018-3516-1
9. Guenzi M, Arman G, Rau C et al. Remission of type 2 diabetes after omega loop gastric bypass for morbid obesity. Surg Endosc 2015; 29 (9): 2669–74. DOI: 10.1007/s00464-014-3987-7
10. Musella M, Susa A, Greco F et al. The laparoscopic mini-gastric bypass: the Italian experience: outcomes from 974 consecutive cases in a multicenter review. Surg Endosc 2014; 28 (1): 156–63. DOI: 10.1007/s00464-013-3141-y
11. Carbajo MA, Luque-de-León E, Jiménez JM et al. Laparoscopic One-Anastomosis Gastric Bypass: Technique, Results, and Long-Term Follow-Up in 1200 Patients. Obes Surg 2017; 27 (5): 1153–67. DOI: 10.1007/s11695-016-2428-1
12. Taha O, Abdelaal M, Abozeid M et al. Outcomes of Omega Loop Gastric Bypass, 6-Years Experience of 1520 Cases. Obes Surg 2017; 27 (8): 1952–60. DOI: 10.1007/s11695-017-2623-8
13. Lee W-J, Yu P-J, Wang W et al. Laparoscopic Roux-en-Y versus mini-gastric bypass for the treatment of morbid obesity: a prospective randomized controlled clinical trial. Ann Surg 2005; 242 (1): 20–8.
14. Lee W-J, Ser K-H, Lee Y-C et al. Laparoscopic Roux-en-Y vs. mini-gastric bypass for the treatment of morbid obesity: a 10-year experience. Obes Surg 2012; 22 (12): 1827–34. DOI: 10.1007/s11695-012-0726-9
15. Quan Y, Huang A, Ye M et al. Efficacy of Laparoscopic Mini Gastric Bypass for Obesity and Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis. Gastroenterol Res Pract 2015; 2015: 152852. DOI: 10.1155/2015/152852
16. Wang F-G, Yan W-M, Yan M, Song M-M. Outcomes of Mini vs Roux-en-Y gastric bypass: A meta-analysis and systematic review. Int J Surg 2018; 56: 7–14. DOI: 10.1016/j.ijsu.2018.05.009
17. Robert M, Espalieu P, Pelascini E et al. Efficacy and safety of one anastomosis gastric bypass versus Roux-en-Y gastric bypass for obesity (YOMEGA): a multicentre, randomised, open-label, non-inferiority trial. Lancet 2019; 6736 (19): 1–11. DOI: 10.1016/S0140-6736(19)30475-1
18. Lee W-J, Chong K, Lin Y-H et al. Laparoscopic sleeve gastrectomy versus single anastomosis (mini-) gastric bypass for the treatment of type 2 diabetes mellitus: 5-year results of a randomized trial and study of incretin effect. Obes Surg 2014; 24 (9): 1552–62. DOI: 10.1007/s11695-014-1344-5
19. Kular KS, Manchanda N, Rutledge R. Analysis of the five-year outcomes of sleeve gastrectomy and mini gastric bypass: a report from the Indian sub-continent. Obes Surg 2014; 24 (10): 1724–8. DOI: 10.1007/s11695-014-1264-4
20. Celik A, Pouwels S, Karaca FC et al. Time to Glycemic Control – an Observational Study of 3 Different Operations. Obes Surg 2017; 27 (3): 694–702. DOI: 10.1007/s11695-016-2344-4
21. Kular KS, Manchanda N, Cheema GK. Seven Years of Mini-Gastric Bypass in Type II Diabetes Patients with a Body Mass Index <35 kg/m(2). Obes Surg 2016; 26 (7): 1457–62. DOI: 10.1007/s11695-015-1941-y
22. Mahawar KK, Kumar P, Carr WR et al. Current status of mini-gastric bypass. J Minim Access Surg 12 (4): 305–10. DOI: 10.4103/0972-9941.181352
23. Noun R, Skaff J, Riachi E et al. One thousand consecutive mini-gastric bypass: short-and long-term outcome. Obes Surg 2012; 22 (5): 697–703. DOI: 10.1007/s11695-012-0618-z
24. Kular KS, Manchanda N, Rutledge R. A 6-year experience with 1,054 mini-gastric bypasses-first study from Indian subcontinent. Obes Surg 2014; 24 (9): 1430–5. DOI: 10.1007/s11695-014-1220-3
25. Peraglie C. Laparoscopic mini-gastric bypass in patients age 60 and older. Surg Endosc 2016; 30 (1): 38–43. DOI: 10.1007/s00464-015-4157-2
26. Bruzzi M, Chevallier J-M, Czernichow S. One-Anastomosis Gastric Bypass: Why Biliary Reflux Remains Controversial? Obes Surg 2017; 27 (2): 545–7. DOI: 10.1007/s11695-016-2480-x
27. Guirat A, Addossari HM. One Anastomosis Gastric Bypass and Risk of Cancer. Obes Surg 2018; 28 (5): 1441–4. DOI: 10.1007/s11695-018-3156-5
28. Keleidari B, Mahmoudieh M, Davarpanah Jazi AH et al. Comparison of the Bile Reflux Frequency in One Anastomosis Gastric Bypass and Roux-en-Y Gastric Bypass: a Cohort Study. Obes Surg 2019. DOI: 10.1007/s11695-018-03683-6
29. Ahuja A, Tantia O, Goyal G et al. MGB-OAGB: Effect of Biliopancreatic Limb Length on Nutritional Deficiency, Weight Loss, and Comorbidity Resolution. Obes Surg 2018; 28 (11): 3439–45. DOI: 10.1007/s11695-018-3405-7
Авторы
И.А.Скляник*, А.В.Кармадонов, М.В.Шестакова
ФГБУ «Национальный медицинский исследовательский центр эндокринологии» Минздрава России, Москва, Россия
*sklyanik.igor@gmail.com
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Igor A. Sklyanik*, Andrey V. Karmadonov, Marina V. Shestakova