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Эндоскопическое стентирование при злокачественных пищеводно-респираторных фистулах
Эндоскопическое стентирование при злокачественных пищеводно-респираторных фистулах
Иванов А.И., Попов В.А., Бурмистров М.В. Эндоскопическое стентирование при злокачественных пищеводно-респираторных фистулах. Consilium Medicum. 2020; 22 (8): 32–35. DOI: 10.26442/20751753.2020.8.200283
DOI: 10.26442/20751753.2020.8.200283
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DOI: 10.26442/20751753.2020.8.200283
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Аннотация
Более 70% всех случаев злокачественных свищей возникает у пациентов с распространенным раком пищевода. Частота их возникновения при неоперабельном раке пищевода увеличилась за последние 30 лет более чем на 10%, что обусловлено более широким применением современных паллиативных методов лечения. Стентирование пищевода у данной тяжелой группы больных является эффективным методом выбора с низкими показателями осложнений. В статье приведены результаты имплантации пищеводных стентов под видеоэндоскопическим контролем при злокачественных эзофагореспираторных свищах в условиях Республиканского клинического онкологического диспансера за период с 2011 по 2019 г. Стенты имплантированы 22 больным с разной злокачественной патологией. В статье проведен анализ сроков и факторов возникновения свищей, а также возникших осложнений, способов их профилактики и методов эндоскопической коррекции. Выполнен анализ продолжительности жизни в зависимости от возраста больных, основного заболевания, локализации и сообщения злокачественных свищей. Успешная имплантация достигнута в 19 случаях. Осложнения отмечены в 5 случаях. Средняя продолжительность жизни больных составила 52 дня. Стентирование пищевода при злокачественных фистулах пищевода и пищеводных анастомозах является эффективным методом выбора паллиативного лечения.
Ключевые слова: рак пищевода, эзофагореспираторный свищ, стентирование.
Key words: esophageal carcinoma, respiratory-digestive fistula, stenting.
Ключевые слова: рак пищевода, эзофагореспираторный свищ, стентирование.
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Key words: esophageal carcinoma, respiratory-digestive fistula, stenting.
Полный текст
Список литературы
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13. Colt HG, Meric B, Dumon JF. Double stents for carcinoma of the esophagus invading the tracheo-bronchial tree. Gastrointest Endosc 1992; 38: 485–9. DOI: 10.1016/s0016-5107(92)70482-9
14. Shin JH, Kim JH, Song HY. Interventional management of esophagorespiratory fistula. Korean J Radiol 2010; 11: 133–40. DOI: 10.3348/kjr.2010.11.2.133
15. Abadal JM, Echenagusia A, Simo G et al. Treatment of malignant esophagorespiratory fistulas with covered stents. Abdom Imaging 2001; 26: 565–9. DOI: 10.1007/s002610000193
16. Saxon RR, Barton RE, Katon RM et al .Treatment of malignant esophageal obstructions with covered metallic Z stents: Long-term results in 52 patients. J Vasc Interv Radiol 1995; 6: 747–54. DOI: 10.1016/s1051-0443(95)71180-0
17. Kishi K, Nakao T, Goto H et al. A fast placement technique for covered tracheobronchial stents in patients with complicated esophagorespiratory fistulas. Cardiovasc Intervent Radiol 2005; 28: 485–9. DOI: 10.1007/s00270-003-0203-x
18. Balazs A, Kupcsulik PK, Galambos Z. Esophagorespiratoryfistulas of tumorous origin. Non-operative management of 264 cases in a 20-year period. Eur J Cardiothorac Surg 2008; 34: 1103–7. DOI: 10.1016/j.ejcts.2008.06.025
19. Nam DH, Shin JH, Song HY et al. Malignant esophageal-tracheobronchial strictures: Parallel placement of covered retrievable expandable nitinol stents. Acta Radiol 2006; 47: 3–9. DOI: 10.1080/02841850500334989
20. Binkert CA, Petersen BD. Two fatal complications after parallel tracheal-esophageal stenting. Cardiovasc Intervent Radiol 2002; 25: 144–7. DOI: 10.1007/s00270-001-0088-5
2. Martini N, Goodner JT, D'Angio GJ et al. Tracheoesophageal fistula due to cancer. J Thorac Cardiovasc Surg 1970; 59: 319–24. DOI: 10.1016/S0022-5223(19)42464-1
3. Balazs A, Galambos Z, Kupcsulik PK. Characteristics of esophagorespiratory fistulas resulting from esophageal cancers: A single-center study on 243 cases in a 20-year period. World J Surg 2009; 33: 994–1001. DOI: 10.1007/s00268-009-9988-3
4. Angorn IB. Intubation in the treatment of carcinoma of the esophagus. World J Surg 1981; 5: 535–41. DOI: 10.1007/BF01655006
5. Duranceau A, Jamieson GG. Malignant tracheoesophageal fistula. Ann ThoracSurg 1984; 37: 346–54. DOI: 10.1016/s0003-4975(10)60745-x
6. Hürtgen M, Herber SC. Treatment of malignant tracheoesophageal fistula. Thorac Surg Clin 2014; 24: 117–27. DOI: 10.1016/j.thorsurg.2013.09.006
7. Shin JH, Song HY, Ko G et al. Esophagorespiratory fistula: Long-term results of palliative treatment with covered expandable metallic stents in 61 patients. Radiology 2004; 232: 252–9. DOI: 10.1148/radiol.2321030733
8. Murthy S, Gonzalez-Stawinski GV, Rozas MS et al. Palliation of malignant aerodigestive fistulae with self-expanding metallic stents. Dis Esophagus 2007; 20: 386–9. DOI: 10.1111/j.1442-2050.2007.00689.x
9. Wang H, Ke M, Li W et al. Chinese expert consensus on diagnosis and management of acquired respiratory-digestive tract fistulas. Thorac Cancer 2018; 9 (11): 1544–55. DOI: 10.1111/1759-7714.12856
10. Włodarczyk JR, Kużdżał J. Safety and efficacy of airway stenting in patients with malignant oesophago-airway fistula. J Thorac Dis 2018; 10 (5): 2731–9. DOI: 10.21037/jtd.2018.05.19
11. Burt M, Diehl W, Martini N et al. Malignant esophagorespiratory fistula: management options and survival. Ann Thorac Surg 1991; 52: 1222–8. DOI: 10.1016/0003-4975(91)90005-b
12. Davydov M, Stilidi I, Bokhyan V et al. Surgical treatment of esophageal carcinoma complicated by fistulas. Eur J Cardiothorac Surg 2001; 20: 405–8. DOI: 10.1016/S1010-7940(01)00796-5
13. Colt HG, Meric B, Dumon JF. Double stents for carcinoma of the esophagus invading the tracheo-bronchial tree. Gastrointest Endosc 1992; 38: 485–9. DOI: 10.1016/s0016-5107(92)70482-9
14. Shin JH, Kim JH, Song HY. Interventional management of esophagorespiratory fistula. Korean J Radiol 2010; 11: 133–40. DOI: 10.3348/kjr.2010.11.2.133
15. Abadal JM, Echenagusia A, Simo G et al. Treatment of malignant esophagorespiratory fistulas with covered stents. Abdom Imaging 2001; 26: 565–9. DOI: 10.1007/s002610000193
16. Saxon RR, Barton RE, Katon RM et al .Treatment of malignant esophageal obstructions with covered metallic Z stents: Long-term results in 52 patients. J Vasc Interv Radiol 1995; 6: 747–54. DOI: 10.1016/s1051-0443(95)71180-0
17. Kishi K, Nakao T, Goto H et al. A fast placement technique for covered tracheobronchial stents in patients with complicated esophagorespiratory fistulas. Cardiovasc Intervent Radiol 2005; 28: 485–9. DOI: 10.1007/s00270-003-0203-x
18. Balazs A, Kupcsulik PK, Galambos Z. Esophagorespiratoryfistulas of tumorous origin. Non-operative management of 264 cases in a 20-year period. Eur J Cardiothorac Surg 2008; 34: 1103–7. DOI: 10.1016/j.ejcts.2008.06.025
19. Nam DH, Shin JH, Song HY et al. Malignant esophageal-tracheobronchial strictures: Parallel placement of covered retrievable expandable nitinol stents. Acta Radiol 2006; 47: 3–9. DOI: 10.1080/02841850500334989
20. Binkert CA, Petersen BD. Two fatal complications after parallel tracheal-esophageal stenting. Cardiovasc Intervent Radiol 2002; 25: 144–7. DOI: 10.1007/s00270-001-0088-5
2. Martini N, Goodner JT, D'Angio GJ et al. Tracheoesophageal fistula due to cancer. J Thorac Cardiovasc Surg 1970; 59: 319–24. DOI: 10.1016/S0022-5223(19)42464-1
3. Balazs A, Galambos Z, Kupcsulik PK. Characteristics of esophagorespiratory fistulas resulting from esophageal cancers: A single-center study on 243 cases in a 20-year period. World J Surg 2009; 33: 994–1001. DOI: 10.1007/s00268-009-9988-3
4. Angorn IB. Intubation in the treatment of carcinoma of the esophagus. World J Surg 1981; 5: 535–41. DOI: 10.1007/BF01655006
5. Duranceau A, Jamieson GG. Malignant tracheoesophageal fistula. Ann ThoracSurg 1984; 37: 346–54. DOI: 10.1016/s0003-4975(10)60745-x
6. Hürtgen M, Herber SC. Treatment of malignant tracheoesophageal fistula. Thorac Surg Clin 2014; 24: 117–27. DOI: 10.1016/j.thorsurg.2013.09.006
7. Shin JH, Song HY, Ko G et al. Esophagorespiratory fistula: Long-term results of palliative treatment with covered expandable metallic stents in 61 patients. Radiology 2004; 232: 252–9. DOI: 10.1148/radiol.2321030733
8. Murthy S, Gonzalez-Stawinski GV, Rozas MS et al. Palliation of malignant aerodigestive fistulae with self-expanding metallic stents. Dis Esophagus 2007; 20: 386–9. DOI: 10.1111/j.1442-2050.2007.00689.x
9. Wang H, Ke M, Li W et al. Chinese expert consensus on diagnosis and management of acquired respiratory-digestive tract fistulas. Thorac Cancer 2018; 9 (11): 1544–55. DOI: 10.1111/1759-7714.12856
10. Włodarczyk JR, Kużdżał J. Safety and efficacy of airway stenting in patients with malignant oesophago-airway fistula. J Thorac Dis 2018; 10 (5): 2731–9. DOI: 10.21037/jtd.2018.05.19
11. Burt M, Diehl W, Martini N et al. Malignant esophagorespiratory fistula: management options and survival. Ann Thorac Surg 1991; 52: 1222–8. DOI: 10.1016/0003-4975(91)90005-b
12. Davydov M, Stilidi I, Bokhyan V et al. Surgical treatment of esophageal carcinoma complicated by fistulas. Eur J Cardiothorac Surg 2001; 20: 405–8. DOI: 10.1016/S1010-7940(01)00796-5
13. Colt HG, Meric B, Dumon JF. Double stents for carcinoma of the esophagus invading the tracheo-bronchial tree. Gastrointest Endosc 1992; 38: 485–9. DOI: 10.1016/s0016-5107(92)70482-9
14. Shin JH, Kim JH, Song HY. Interventional management of esophagorespiratory fistula. Korean J Radiol 2010; 11: 133–40. DOI: 10.3348/kjr.2010.11.2.133
15. Abadal JM, Echenagusia A, Simo G et al. Treatment of malignant esophagorespiratory fistulas with covered stents. Abdom Imaging 2001; 26: 565–9. DOI: 10.1007/s002610000193
16. Saxon RR, Barton RE, Katon RM et al .Treatment of malignant esophageal obstructions with covered metallic Z stents: Long-term results in 52 patients. J Vasc Interv Radiol 1995; 6: 747–54. DOI: 10.1016/s1051-0443(95)71180-0
17. Kishi K, Nakao T, Goto H et al. A fast placement technique for covered tracheobronchial stents in patients with complicated esophagorespiratory fistulas. Cardiovasc Intervent Radiol 2005; 28: 485–9. DOI: 10.1007/s00270-003-0203-x
18. Balazs A, Kupcsulik PK, Galambos Z. Esophagorespiratoryfistulas of tumorous origin. Non-operative management of 264 cases in a 20-year period. Eur J Cardiothorac Surg 2008; 34: 1103–7. DOI: 10.1016/j.ejcts.2008.06.025
19. Nam DH, Shin JH, Song HY et al. Malignant esophageal-tracheobronchial strictures: Parallel placement of covered retrievable expandable nitinol stents. Acta Radiol 2006; 47: 3–9. DOI: 10.1080/02841850500334989
20. Binkert CA, Petersen BD. Two fatal complications after parallel tracheal-esophageal stenting. Cardiovasc Intervent Radiol 2002; 25: 144–7. DOI: 10.1007/s00270-001-0088-5
________________________________________________
2. Martini N, Goodner JT, D'Angio GJ et al. Tracheoesophageal fistula due to cancer. J Thorac Cardiovasc Surg 1970; 59: 319–24. DOI: 10.1016/S0022-5223(19)42464-1
3. Balazs A, Galambos Z, Kupcsulik PK. Characteristics of esophagorespiratory fistulas resulting from esophageal cancers: A single-center study on 243 cases in a 20-year period. World J Surg 2009; 33: 994–1001. DOI: 10.1007/s00268-009-9988-3
4. Angorn IB. Intubation in the treatment of carcinoma of the esophagus. World J Surg 1981; 5: 535–41. DOI: 10.1007/BF01655006
5. Duranceau A, Jamieson GG. Malignant tracheoesophageal fistula. Ann ThoracSurg 1984; 37: 346–54. DOI: 10.1016/s0003-4975(10)60745-x
6. Hürtgen M, Herber SC. Treatment of malignant tracheoesophageal fistula. Thorac Surg Clin 2014; 24: 117–27. DOI: 10.1016/j.thorsurg.2013.09.006
7. Shin JH, Song HY, Ko G et al. Esophagorespiratory fistula: Long-term results of palliative treatment with covered expandable metallic stents in 61 patients. Radiology 2004; 232: 252–9. DOI: 10.1148/radiol.2321030733
8. Murthy S, Gonzalez-Stawinski GV, Rozas MS et al. Palliation of malignant aerodigestive fistulae with self-expanding metallic stents. Dis Esophagus 2007; 20: 386–9. DOI: 10.1111/j.1442-2050.2007.00689.x
9. Wang H, Ke M, Li W et al. Chinese expert consensus on diagnosis and management of acquired respiratory-digestive tract fistulas. Thorac Cancer 2018; 9 (11): 1544–55. DOI: 10.1111/1759-7714.12856
10. Włodarczyk JR, Kużdżał J. Safety and efficacy of airway stenting in patients with malignant oesophago-airway fistula. J Thorac Dis 2018; 10 (5): 2731–9. DOI: 10.21037/jtd.2018.05.19
11. Burt M, Diehl W, Martini N et al. Malignant esophagorespiratory fistula: management options and survival. Ann Thorac Surg 1991; 52: 1222–8. DOI: 10.1016/0003-4975(91)90005-b
12. Davydov M, Stilidi I, Bokhyan V et al. Surgical treatment of esophageal carcinoma complicated by fistulas. Eur J Cardiothorac Surg 2001; 20: 405–8. DOI: 10.1016/S1010-7940(01)00796-5
13. Colt HG, Meric B, Dumon JF. Double stents for carcinoma of the esophagus invading the tracheo-bronchial tree. Gastrointest Endosc 1992; 38: 485–9. DOI: 10.1016/s0016-5107(92)70482-9
14. Shin JH, Kim JH, Song HY. Interventional management of esophagorespiratory fistula. Korean J Radiol 2010; 11: 133–40. DOI: 10.3348/kjr.2010.11.2.133
15. Abadal JM, Echenagusia A, Simo G et al. Treatment of malignant esophagorespiratory fistulas with covered stents. Abdom Imaging 2001; 26: 565–9. DOI: 10.1007/s002610000193
16. Saxon RR, Barton RE, Katon RM et al .Treatment of malignant esophageal obstructions with covered metallic Z stents: Long-term results in 52 patients. J Vasc Interv Radiol 1995; 6: 747–54. DOI: 10.1016/s1051-0443(95)71180-0
17. Kishi K, Nakao T, Goto H et al. A fast placement technique for covered tracheobronchial stents in patients with complicated esophagorespiratory fistulas. Cardiovasc Intervent Radiol 2005; 28: 485–9. DOI: 10.1007/s00270-003-0203-x
18. Balazs A, Kupcsulik PK, Galambos Z. Esophagorespiratoryfistulas of tumorous origin. Non-operative management of 264 cases in a 20-year period. Eur J Cardiothorac Surg 2008; 34: 1103–7. DOI: 10.1016/j.ejcts.2008.06.025
19. Nam DH, Shin JH, Song HY et al. Malignant esophageal-tracheobronchial strictures: Parallel placement of covered retrievable expandable nitinol stents. Acta Radiol 2006; 47: 3–9. DOI: 10.1080/02841850500334989
20. Binkert CA, Petersen BD. Two fatal complications after parallel tracheal-esophageal stenting. Cardiovasc Intervent Radiol 2002; 25: 144–7. DOI: 10.1007/s00270-001-0088-5
Авторы
А.И. Иванов*1,2, В.А. Попов1,3, М.В. Бурмистров1,3
1 Казанская государственная медицинская академия – филиал ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России, Казань, Россия;
2 ГАУЗ «Республиканский клинический онкологический диспансер» Минздрава Республики Татарстан, Казань, Россия;
3 ГАУЗ «Республиканская клиническая больница» Минздрава Республики Татарстан, Казань, Россия
*a.i.ivanov@inbox.ru
1 Kazan State Medical Academy – branch of the Russian Medical Academy of Continuous Professional Education, Kazan, Russia;
2 Republican Oncology Clinical Dispensery, Kazan, Russia;
3 Republican Clinical Hospital, Kazan, Russia
*a.i.ivanov@inbox.ru
1 Казанская государственная медицинская академия – филиал ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России, Казань, Россия;
2 ГАУЗ «Республиканский клинический онкологический диспансер» Минздрава Республики Татарстан, Казань, Россия;
3 ГАУЗ «Республиканская клиническая больница» Минздрава Республики Татарстан, Казань, Россия
*a.i.ivanov@inbox.ru
________________________________________________
1 Kazan State Medical Academy – branch of the Russian Medical Academy of Continuous Professional Education, Kazan, Russia;
2 Republican Oncology Clinical Dispensery, Kazan, Russia;
3 Republican Clinical Hospital, Kazan, Russia
*a.i.ivanov@inbox.ru
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