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Клинический случай успешного эндоваскулярного лечения рецидива венокорпоральной эректильной дисфункции c использованием жидкого неадгезивного эмболизирующего агента «КАП»
© ООО «КОНСИЛИУМ МЕДИКУМ», 2025 г.
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Ioseliani DG, Koledinskiy AG, Semitko SP, Rapoport LM, Asadov DA, Petrovskii NV, Gyulmisaryan KV, Fomenko VV, Kibets SA, Chernysheva IE, Glybochko PV. Successful endovascular treatment of recurrent venocorporeal erectile dysfunction using a liquid non-adhesive embolizing agent "KAP". Case report. Consilium Medicum. 2025;27(1):18–25. DOI: 10.26442/20751753.2025.1.203096
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Ключевые слова: эректильная дисфункция, венозная утечка, эндоваскулярная эмболизация
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According to the Russian Society of Urologists, almost half of the male population of the country aged 27 to 77 suffers from erectile dysfunction (ED). ED should be considered not only as a serious medical nosology, but also as an important socio-psychological problem of national importance due to its demographic significance. There are many methods of treating ED, including drug therapy and penile prosthetics, as well as certain psychotherapeutic measures. The world's experience in combating this disease allows us to assert that an important condition for determining the correct approach to treating ED is an accurate diagnosis of the causes of ED. Among the many causes of ED, vascular causes are quite common. Given the rapid development of endovascular and low-traumatic approaches to vascular pathology, the method of improving the inflow and obstructing the outflow in vasculogenic ED is becoming increasingly obvious and effective. The presented article discusses a clinical case of successful endovascular complex treatment of recurrent venocorporeal ED in a young patient.
Keywords: erectile dysfunction, venous leak, endovascular embolization
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16. Wang GY, Xu CC, Wu KR, et al. Application value of Toshiba 320-row dynamic volumetric CT angiography in the diagnosis of venous erectile dysfunction. Zhonghua Nan Ke Xue. 2016;22(7):635-40 (in Chinese).
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18. Doppalapudi SK, Wajswol E, Shukla PA, et al. Endovascular Therapy for Vasculogenic Erectile Dysfunction: A Systematic Review and Meta-Analysis of Arterial and Venous Therapies. J Vasc Interv Radiol. 2019;30(8):1251-8.e2. DOI:10.1016/j.jvir.2019.01.024
19. Fernández Arjona M, Oteros R, Zarca M, et al. Percutaneous embolization for erectile dysfunction due to venous leakage: prognostic factors for a good therapeutic result. Eur Urol. 2001;39(1):15-9. DOI:10.1159/000052406
20. Kutlu R, Soylu A. Deep dorsal vein embolization with N-butyl-2-cyanoacrylate and lipiodol mixture in venogenic erectile dysfunction: early and late results. Radiol Oncol. 2009;43(1):17-25. DOI:10.2478/v10019-009-0011-2
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1. Rossiiskoe obshchestvo urologov. Klinicheskie rekomendatsii. Erektil'naia disfunktsiia. 2021 (in Russian).
2. Korneyev IA, Alexeeva TA, Al-Shukri SH, et al. Prevalence and risk factors for erectile dysfunction and lower urinary tract symptoms in Russian Federation men: analysis from a national population-based multicenter study. Int J Impot Res. 2016;28(2):74-9. DOI:10.1038/ijir.2016.8
3. Urologiia: uchebnik. Pod red. P.V. Glybochko, Iu.G. Aliaeva. 3-e izd., pererab. i dop. Moscow: GEOTAR-Media, 2013 (in Russian).
4. Ioseliani DG, Rapoport LM, Semitko SP, et al. Erectile dysfunction: current state of the problem, diagnostic methods and X-ray endoscopic surgical treatment. Andrology and Genital Surgery. 2024;25(3):24-35 (in Russian). DOI:10.62968/2070-9781-2024-25-3-24-35
5. Corona G, Cucinotta D, Di Lorenzo G, et al. The Italian Society of Andrology and Sexual Medicine (SIAMS), along with ten other Italian Scientific Societies, guidelines on the diagnosis and management of erectile dysfunction. J Endocrinol Invest. 2023;46(6):1241-24. DOI:10.1007/s40618-023-02015-5
6. Doppalapudi SK, Wajswol E, Shukla PA, et al. Endovascular Therapy for Vasculogenic Erectile Dysfunction: A Systematic Review and Meta-Analysis of Arterial and Venous Therapies. J Vasc Interv Radiol. 2019;30(8):1251-8.e2. DOI:10.1016/j.jvir.2019.01.024
7. Wespes E, Schulman CC. Venous leakage: surgical treatment of a curable cause of impotence. J Urol. 1985;133(5):796-8. DOI:10.1016/s0022-5347(17)49231-7.
8. Lewis RW, Puyau FA. Procedures for decreasing venous drainage. Semin Urol. 1986;4(4):263-72
9. Koledinsky AG, Sidelnikov AV, Shiryaev AI. First experience of using the transbasilar approach for prostatic venous plexus embolization during the erectile dysfunction treatment. International Journal of Interventional Cardioangiology. 2020;62:9-16 (in Russian).
10. Aschenbach R, Steiner T, Kerl MJ, et al. Endovascular embolisation therapy in men with erectile impotence due to veno-occlusive dysfunction. Eur J Radiol. 2013;82(3):504-7. DOI:10.1016/j.ejrad.2012.10.030
11. Hoppe H, Hirschle D, Schumacher MC, et al. Erectile dysfunction: role of computed tomography cavernosography in the diagnosis and treatment planning of venous leak. CVIR Endovasc. 2023;6(1):56. DOI:10.1186/s42155-023-00403-9
12. Diehm N, Pelz S, Kalka C, et al. Venous Leak Embolization in Patients with Venogenic Erectile Dysfunction via Deep Dorsal Penile Vein Access: Safety and Early Efficacy. Cardiovasc Intervent Radiol. 2023;46(5):610-1. DOI:10.1007/s00270-023-03412-2
13. Fournier GRJr, Juenemann KP, Lue TF, Tanagho EA. Mechanisms of venous occlusion during canine penile erection: an anatomic demonstration. J Urol. 1987;137(1):163-7. DOI:10.1016/s0022-5347(17)43911-5
14. Fiałkowski T, Cegielski M. Incarceration of the penis in a metal ring. Pol Przegl Chir. 1954;26(5):419-27.
15. Xu CC, Ruan XZ, Tang YF, et al. Diagnostic value of four-dimensional CT angiography in arterial erectile dysfunction using 320-detector row dynamic volume CT. Biosci Rep. 2017;37(4):BSR20170200. DOI:10.1042/BSR20170200
16. Wang GY, Xu CC, Wu KR, et al. Application value of Toshiba 320-row dynamic volumetric CT angiography in the diagnosis of venous erectile dysfunction. Zhonghua Nan Ke Xue. 2016;22(7):635-40 (in Chinese).
17. Rebonato A, Maiettini D, Ceccherini C, et al. Endovascular treatment of recurrent erectile dysfunction due to venous occlusive disease. Asian J Androl. 2017;19(4):509-10. DOI:10.4103/1008-682X.179160
18. Doppalapudi SK, Wajswol E, Shukla PA, et al. Endovascular Therapy for Vasculogenic Erectile Dysfunction: A Systematic Review and Meta-Analysis of Arterial and Venous Therapies. J Vasc Interv Radiol. 2019;30(8):1251-8.e2. DOI:10.1016/j.jvir.2019.01.024
19. Fernández Arjona M, Oteros R, Zarca M, et al. Percutaneous embolization for erectile dysfunction due to venous leakage: prognostic factors for a good therapeutic result. Eur Urol. 2001;39(1):15-9. DOI:10.1159/000052406
20. Kutlu R, Soylu A. Deep dorsal vein embolization with N-butyl-2-cyanoacrylate and lipiodol mixture in venogenic erectile dysfunction: early and late results. Radiol Oncol. 2009;43(1):17-25. DOI:10.2478/v10019-009-0011-2
1ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский Университет), Москва, Россия;
2ФГАОУ ВО «Российский университет дружбы народов им. Патриса Лумумбы», Москва, Россия;
3ГБУЗ Московской области «Сергиево-Посадская больница», Сергиев-Посад, Россия;
4ООО «СМ-Клиника», Москва, Россия
*asadov_djamil@mail.ru
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David G. Ioseliani1, Anton G. Koledinskiy2–4, Sergey P. Semitko1, Leonid M. Rapoport1, Dzhamil A. Asadov*1,2, Nick V. Petrovskii1, Karen V. Gyulmisaryan1, Victoria V. Fomenko1, Sergei A. Kibets4, Irina E. Chernysheva1, Petr V. Glybochko1
1Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia;
2Patrice Lumumba People’s Friendship University of Russia (RUDN University), Moscow, Russia;
3Sergiev Posad Hospital, Sergiev Posad, Russia;
4SM-Clinic LLC, Moscow, Russia
*asadov_djamil@mail.ru