В статье освещены современные принципы оказания неотложной помощи при массивной кровопотере в гинекологии. Рассмотрены вопросы своевременного использования хирургического местного гемостаза, использования эффективных гемостатических препаратов, рационального применения компонентов крови и адекватного восстановления транспорта кислорода, коррекции объема циркулирующей крови.
1. Барышев Б.А. Кровезаменители. Компоненты крови: Справочник для врачей. Изд. 2-е, перераб. и доп. СПб.: Человек, 2005.
2. Баландин В.В., Галстян Г.М., Горобец Е.С. и др. Инфузионно-трансфузионная терапия в клинической медицине: Руководство для врачей. Под ред. Б.Р.Гельфанда. М.: Медицинское информационное агентство, 2009.
3. Куликов А.В. Инфузионно-трансфузионная терапия в гинекологии. Глава в Национальном руководстве «Гинекология». ГЭОТАР-медиа, 2007.
4. Куликов А.В., Мартиросян С.В., Обоскалова Т.А. Протокол неотложной помощи при кровотечении в акушерстве. Методические рекомендации. Екатеринбург, 2010.
5. Профилактика и терапия массивной кровопотери в акушерстве (медицинская технология). Научный центр акушерства, гинекологии и перинатологии им. акад. В.И.Кулакова Минздравсоцразвития РФ. М., 2010.
6. AAGBI safetyguidline. Blood Transfusion and the Anaesthetist Intra-operative Cell Salvage The Association of Anaesthetists of Great Britain and Ireland 2009.
7. AAGBI safety guidelines. Blood transfusion and the anaesthetist: management of massive haemorrhage. Association of Anaesthetists of Great Britain and Ireland 2010.
8. Angele MK, Schneider CP, Chaudry IH. Bench-to-bedside review: latest results in hemorrhagic shock. Crit Care 2008; 12 (4): 218.
9. Arya RC, Wander GS, Gupta P. Blood component therapy: Which, when and how much J Anaesthesiol Clin Pharmacol 2011; 27 (2): 278–84.
10. Bonanno FG. Clinical pathology of the shock syndromes. J Emerg Trauma Shock 2011; 4 (2): 233–43.
11. Bonanno FG. Physiopathology of shock. J Emerg Trauma Shock 2011; 4 (2): 222–32.
12. Bunn F, Trivedi D, Ashraf S. Colloid solutions for fluid resuscitation. Cochrane Database Syst Rev 2011; 3: CD001319.
13. Finnish Medical Society Duodecim. Blood transfusion: indications and administration. In: EBM Guidelines. Evidence-Based Medicine [CD-ROM]. Helsinki, Finland: Duodecim Medical Publications Ltd 2006.
14. Franchini M, Franchi M, Bergamini V et al. A critical review on the use of recombinant factor VIIa in life-threatening obstetric postpartum hemorrhage. Semin Thromb Hemost 2008; 34 (1): 104–12.
15. Gutierrez G, Reines HD, Wulf-Gutierrez ME. Clinical review: Hemorrhagic shock. Crit Care 2004; 8 (5): 373–81.
16. Hardy J, Moerloose P, Samama M. Massive transfusion and coagulopathy: pathophysiology and implications for clinical management. Canad J Anesth 2004; 51: 293–310.
17. Henry DA, Carless PA, Moxey AJ et al. Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion. Cochrane Database of Systematic Reviews 2011; Is. 3. Art. No: CD001886. DOI: 10.1002/14651858. CD001886.pub4.
18. Lee JH, Song JW, Song KS. Diagnosis of Overt Disseminated Intravascular Coagulation: A Comparative Study Using Criteria from the International Society Versus the Korean Society on Thrombosis and Hemostasis. Yonsei Med J 2007; 48 (4): 595–600.
19. Levi M, De Jonge E. Volume replacement and coagulation impairment. Minerva Anestesiol 2005; 71 (12, Suppl. 1):11–6.
20. Levi M, Toh CH, Thachil J, Watson HG. Guidelines for the diagnosis and management of disseminated intravascular coagulation. British Committee for Standards in Haematology. Br J Haematol 2009; 145 (1): 24–33.
21. Mannucci PM, Levi M. Prevention and Treatment of Major Blood Loss. NEJM 2007; 356: 2301–11.
22. Marik PE, Monnet X, Teboul JL. Hemodynamic parameters to guide fluid therapy. Ann Intensive Care 2011; 1: 1.
23. Nascimento B, Callum J, RubenfeldG. Clinical review: Fresh frozen plasma in massive bleedings – more questions than answers. Crit Care 2010; 14 (1): 202.
24. Pahlavan P, Nezhat C, Nezhat C. Hemorrhage in obstetrics and gynecology. Curr Opin Obstet Gynecol 2001; 13 (4): 419–24.
25. Perel P, Roberts I. Colloids versus crystalloids for fluid resuscitation in critically ill patients. Cochrane Database Syst Rev 2011; 3: CD000567.
26. Practice guidelines for perioperative blood transfusion and adjuvant therapies: an updated report by the American Society of Anestiologists Task Force on Perioperative Blood Transfusion and Adjuvant Therapies. Anesthesiology 2006; 105 (1): 198–208.
27. Roberts I, Shakur H, Ker K, Coats T. On behalf of the CRASH-2 Trial collaborators. Antifibrinolytic drugs for acute traumatic injury. Cochrane Database of Systematic Rev 2011; Is. 1. Art. No: CD004896. DOI: 10.1002/14651858. CD004896. pub3
28. Rossaint R, Bouillon B, Cerny V et al. Management of bleeding following major trauma: an updated European guideline Crit Care 2010; 14 (2): R52.
29. Santoso JT, Saunders BA, Grosshart K. Massive blood loss and transfusion in obstetrics and gynecology. Obstet Gynecol Surv 2005; 60 (12): 827–37.
30. Scalea TM. Hemostatic resuscitation for acute traumatic coagulopathy. Scand J Trauma Resusc Emerg Med 2011; 19: 2.
31. Schantz-Dunn J, Nawal M. The Use of Blood in Obstetrics and Gynecology in the Developing World Rev Obstet Gynecol 2011; 4 (2): 86–91.
32. Sindelić R, Vlajković G, Marković D, Bumbasirević V. Assessment of perioperative fluid balance. Acta ChirIugosl 2009; 56 (1): 67–76.
33. Spahn DR, Cerny V, Coats T J et al. Management of bleeding following major trauma: a European guideline. Crit Care 2007; 11 (1): R17.
34. Stone HH, Strom PR, Mullins RJ. Management of the major coagulopathy with onset during laparotomy. Ann Surg 1983; 197: 532–5.
35. Thachil J, Toh CH. Disseminated intravascular coagulation in obstetric disorders and its acute haematological management. Blood Rev 2009; 23 (4): 167–76.
36. Transfusion Guidelines For Blood Components. Recommendations of the Medical Advisory Committee of the American Red Cross Blood Services. N Eng Reg 2003.
37. Voils S. Pharmacologic interventions for the management of critical bleeding. Pharmacotherapy 2007; 27 (9 Pt 2): 69S-84S.
38. Williams AP, Gettinger A. Transfusion therapy in the intensive care unit. Curr Opin Anaesthesiol 2006; 19 (2): 127–31.
39. Wise A, Clark V. Strategies to manage major obstetric haemorrhage. Curr Opin Anaesthesiol 2008; 21 (3): 281–7.
________________________________________________
1. Барышев Б.А. Кровезаменители. Компоненты крови: Справочник для врачей. Изд. 2-е, перераб. и доп. СПб.: Человек, 2005.
2. Баландин В.В., Галстян Г.М., Горобец Е.С. и др. Инфузионно-трансфузионная терапия в клинической медицине: Руководство для врачей. Под ред. Б.Р.Гельфанда. М.: Медицинское информационное агентство, 2009.
3. Куликов А.В. Инфузионно-трансфузионная терапия в гинекологии. Глава в Национальном руководстве «Гинекология». ГЭОТАР-медиа, 2007.
4. Куликов А.В., Мартиросян С.В., Обоскалова Т.А. Протокол неотложной помощи при кровотечении в акушерстве. Методические рекомендации. Екатеринбург, 2010.
5. Профилактика и терапия массивной кровопотери в акушерстве (медицинская технология). Научный центр акушерства, гинекологии и перинатологии им. акад. В.И.Кулакова Минздравсоцразвития РФ. М., 2010.
6. AAGBI safetyguidline. Blood Transfusion and the Anaesthetist Intra-operative Cell Salvage The Association of Anaesthetists of Great Britain and Ireland 2009.
7. AAGBI safety guidelines. Blood transfusion and the anaesthetist: management of massive haemorrhage. Association of Anaesthetists of Great Britain and Ireland 2010.
8. Angele MK, Schneider CP, Chaudry IH. Bench-to-bedside review: latest results in hemorrhagic shock. Crit Care 2008; 12 (4): 218.
9. Arya RC, Wander GS, Gupta P. Blood component therapy: Which, when and how much J Anaesthesiol Clin Pharmacol 2011; 27 (2): 278–84.
10. Bonanno FG. Clinical pathology of the shock syndromes. J Emerg Trauma Shock 2011; 4 (2): 233–43.
11. Bonanno FG. Physiopathology of shock. J Emerg Trauma Shock 2011; 4 (2): 222–32.
12. Bunn F, Trivedi D, Ashraf S. Colloid solutions for fluid resuscitation. Cochrane Database Syst Rev 2011; 3: CD001319.
13. Finnish Medical Society Duodecim. Blood transfusion: indications and administration. In: EBM Guidelines. Evidence-Based Medicine [CD-ROM]. Helsinki, Finland: Duodecim Medical Publications Ltd 2006.
14. Franchini M, Franchi M, Bergamini V et al. A critical review on the use of recombinant factor VIIa in life-threatening obstetric postpartum hemorrhage. Semin Thromb Hemost 2008; 34 (1): 104–12.
15. Gutierrez G, Reines HD, Wulf-Gutierrez ME. Clinical review: Hemorrhagic shock. Crit Care 2004; 8 (5): 373–81.
16. Hardy J, Moerloose P, Samama M. Massive transfusion and coagulopathy: pathophysiology and implications for clinical management. Canad J Anesth 2004; 51: 293–310.
17. Henry DA, Carless PA, Moxey AJ et al. Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion. Cochrane Database of Systematic Reviews 2011; Is. 3. Art. No: CD001886. DOI: 10.1002/14651858. CD001886.pub4.
18. Lee JH, Song JW, Song KS. Diagnosis of Overt Disseminated Intravascular Coagulation: A Comparative Study Using Criteria from the International Society Versus the Korean Society on Thrombosis and Hemostasis. Yonsei Med J 2007; 48 (4): 595–600.
19. Levi M, De Jonge E. Volume replacement and coagulation impairment. Minerva Anestesiol 2005; 71 (12, Suppl. 1):11–6.
20. Levi M, Toh CH, Thachil J, Watson HG. Guidelines for the diagnosis and management of disseminated intravascular coagulation. British Committee for Standards in Haematology. Br J Haematol 2009; 145 (1): 24–33.
21. Mannucci PM, Levi M. Prevention and Treatment of Major Blood Loss. NEJM 2007; 356: 2301–11.
22. Marik PE, Monnet X, Teboul JL. Hemodynamic parameters to guide fluid therapy. Ann Intensive Care 2011; 1: 1.
23. Nascimento B, Callum J, RubenfeldG. Clinical review: Fresh frozen plasma in massive bleedings – more questions than answers. Crit Care 2010; 14 (1): 202.
24. Pahlavan P, Nezhat C, Nezhat C. Hemorrhage in obstetrics and gynecology. Curr Opin Obstet Gynecol 2001; 13 (4): 419–24.
25. Perel P, Roberts I. Colloids versus crystalloids for fluid resuscitation in critically ill patients. Cochrane Database Syst Rev 2011; 3: CD000567.
26. Practice guidelines for perioperative blood transfusion and adjuvant therapies: an updated report by the American Society of Anestiologists Task Force on Perioperative Blood Transfusion and Adjuvant Therapies. Anesthesiology 2006; 105 (1): 198–208.
27. Roberts I, Shakur H, Ker K, Coats T. On behalf of the CRASH-2 Trial collaborators. Antifibrinolytic drugs for acute traumatic injury. Cochrane Database of Systematic Rev 2011; Is. 1. Art. No: CD004896. DOI: 10.1002/14651858. CD004896. pub3
28. Rossaint R, Bouillon B, Cerny V et al. Management of bleeding following major trauma: an updated European guideline Crit Care 2010; 14 (2): R52.
29. Santoso JT, Saunders BA, Grosshart K. Massive blood loss and transfusion in obstetrics and gynecology. Obstet Gynecol Surv 2005; 60 (12): 827–37.
30. Scalea TM. Hemostatic resuscitation for acute traumatic coagulopathy. Scand J Trauma Resusc Emerg Med 2011; 19: 2.
31. Schantz-Dunn J, Nawal M. The Use of Blood in Obstetrics and Gynecology in the Developing World Rev Obstet Gynecol 2011; 4 (2): 86–91.
32. Sindelić R, Vlajković G, Marković D, Bumbasirević V. Assessment of perioperative fluid balance. Acta ChirIugosl 2009; 56 (1): 67–76.
33. Spahn DR, Cerny V, Coats T J et al. Management of bleeding following major trauma: a European guideline. Crit Care 2007; 11 (1): R17.
34. Stone HH, Strom PR, Mullins RJ. Management of the major coagulopathy with onset during laparotomy. Ann Surg 1983; 197: 532–5.
35. Thachil J, Toh CH. Disseminated intravascular coagulation in obstetric disorders and its acute haematological management. Blood Rev 2009; 23 (4): 167–76.
36. Transfusion Guidelines For Blood Components. Recommendations of the Medical Advisory Committee of the American Red Cross Blood Services. N Eng Reg 2003.
37. Voils S. Pharmacologic interventions for the management of critical bleeding. Pharmacotherapy 2007; 27 (9 Pt 2): 69S-84S.
38. Williams AP, Gettinger A. Transfusion therapy in the intensive care unit. Curr Opin Anaesthesiol 2006; 19 (2): 127–31.
39. Wise A, Clark V. Strategies to manage major obstetric haemorrhage. Curr Opin Anaesthesiol 2008; 21 (3): 281–7.
Авторы
А.В.Куликов
ГБОУ ВПО Уральская государственная медицинская академия Минздравсоцразвития РФ, Екатеринбург