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Качество жизни женщин как критерий эффективности лечения предменструального синдрома
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Аннотация
Качество жизни – один из критериев оценки эффективности проводимой терапии. Целью исследования было изучение показателей качества жизни пациенток с предменструальным синдромом средней и тяжелой степени тяжести до и после терапии комбинированным микродозированным контрацептивом, содержащим 20 мкг этинилэстрадиола и 3 мг дроспиренона в режиме 24/4. Под наблюдением находились 122 пациентки в возрасте 16–45 лет. Для оценки качества жизни и влияния предменструального синдрома на разные аспекты жизни пациентки в конце лютеиновой фазы менструального цикла дважды – до и после лечения – заполнили опросник Medical Outcomes Study – Short Form (MOS-SF-36). После лечения было выявлено статистически значимое уменьшение деформации показателей как физической, так и психологической компоненты здоровья.
Ключевые слова: предменструальный синдром, качество жизни, комбинированные микродозированные контрацептивы, дроспиренон.
Ключевые слова: предменструальный синдром, качество жизни, комбинированные микродозированные контрацептивы, дроспиренон.
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Quality of life is one of the criteria for therapy effectiveness assessment. The study’s aim was to assess the indicators of quality of life of patients with premenstrual syndrome (PMS) of moderate and severe gravity before and after combined therapy via micro dosed contraceptives containing 20 mcg of ethinyl estradiol and 3 mg drospirenone in a 24/4 regimen. 122 patients aged 16–45 years were observed. To assess the quality of life and the impact of PMS on different aspects of life, patients in the late luteal phase of the menstrual cycle have filled twice – before and after treatment, a Medical Outcomes Study – Short Form (MOS-SF-36) questionnaire. After treatment a statistically significant reduction in the deformation parameters, both physical and psychological components of health were shown.
Key words: premenstrual syndrome, quality of life, combined micro dosed contraceptives, drospirenone.
Полный текст
Список литературы
1. Prilepskaya VN, Ledina AV, Tagiyeva AV, Revazova FS. Vitex agnus castus: Successful treatment of severe premenstrual syndrome. Maturitas 2006; 55 (1): s55–s63.
2. Halbreich U, Monacelli E. Some clues to the etiology of premenstrual syndrome/premenstrual dysphoric disorder. Prim Psychiatry 2004; 11: 33–40.
3. Kikuchi H, Nakatani Y, Seki Y. Decreased blood serotonin in the premenstrual phase enhances negative mood in healthy women. J Psychosom Obstet Gynaecol 2010; 31 (2): 83–9.
4. Rapkin AJ, Mikacich JA. Premenstrual dysphoric disorder and severe premenstrual syndrome in adolescents. Paediatr Drugs 2013; 15 (3): 191–202.
5. Ware JE, Snow KK, Kosinski M et al. SF-36 Health Survey. Manual and n interpretation guide. The Health Institute. New England Medical Center. Boston, 1993: p. 159.
6. Headey B, Wearing A. Coping with the social environment: the relationship between life events, coping strategies and psychological distress. Community Health Study 1988; 12 (4): 444–52.
7. Nuckols TK, Escarce JJ, Asch SM. The effects of quality of care on costs: a conceptual framework. Milbank Q 2013; 91 (2): 316–53.
8. Salek MS et al. J Drug Dev 1992; 5 (3): 137.
9. Chawla A, Swindle R, Long S et al. Premenstrual dysphoric disorder: is there an economic burden of illness? Med Care 2002; 40 (11): 1101–12.
10. Halbreich U. The etiology, biology, and evolving pathology of premenstrual syndromes – Psychoneuroendocrinology 2003; 28 (3): 55–99.
11. Balaha MH et al. The phenomenology of premenstrual syndrome in female medical students: a cross sectional study. Pan Afr Med J 2010; 23 (5): 4.
12. Johnson SR. The epidemiology and social impact of premenstrual symptoms. Clin Obstet Gynecol 1987; 30 (2): 367–76.
13. Bancroft J. The menstrual cycle and the well being of women. Soc Sci Med 1995; 41 (6): 785–91.
14. Heinemann LA et al. Intercountry assessment of the impact of severe premenstrual disorders on work and daily activities. Health Care Women Int 2012; 33 (2): 109–24.
15. Kollipaka R, Arounassalame B, Lakshminarayanan S. Does psychosocial stress influence menstrual abnormalities in medical students? J Obstet Gynaecol 2013; 33 (5): 489–93.
16. Delara M, Ghofranipour F, Azadfallah P et al. Health related quality of life among adolescents with premenstrual disorders: a cross sectional study. Health Qual Life Outcomes 2012; 1 (10): 1.
17. Steiner M, Haskett RF, Carroll BJ. Premenstrual tension syndrome: the development of research diagnostic criteria and new rating scales. Acta Psychiatr Scand 1980; 62 (2): 177–90.
18. Ware JE, Sherbourne CD. The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care 1992; 30 (6): 473–83.
19. Moolenaar LM et al. Economic evaluation studies in reproductive medicine: a systematic review of methodologic quality. Fertil Steril 2013; 99 (6): 1689–94.
2. Halbreich U, Monacelli E. Some clues to the etiology of premenstrual syndrome/premenstrual dysphoric disorder. Prim Psychiatry 2004; 11: 33–40.
3. Kikuchi H, Nakatani Y, Seki Y. Decreased blood serotonin in the premenstrual phase enhances negative mood in healthy women. J Psychosom Obstet Gynaecol 2010; 31 (2): 83–9.
4. Rapkin AJ, Mikacich JA. Premenstrual dysphoric disorder and severe premenstrual syndrome in adolescents. Paediatr Drugs 2013; 15 (3): 191–202.
5. Ware JE, Snow KK, Kosinski M et al. SF-36 Health Survey. Manual and n interpretation guide. The Health Institute. New England Medical Center. Boston, 1993: p. 159.
6. Headey B, Wearing A. Coping with the social environment: the relationship between life events, coping strategies and psychological distress. Community Health Study 1988; 12 (4): 444–52.
7. Nuckols TK, Escarce JJ, Asch SM. The effects of quality of care on costs: a conceptual framework. Milbank Q 2013; 91 (2): 316–53.
8. Salek MS et al. J Drug Dev 1992; 5 (3): 137.
9. Chawla A, Swindle R, Long S et al. Premenstrual dysphoric disorder: is there an economic burden of illness? Med Care 2002; 40 (11): 1101–12.
10. Halbreich U. The etiology, biology, and evolving pathology of premenstrual syndromes – Psychoneuroendocrinology 2003; 28 (3): 55–99.
11. Balaha MH et al. The phenomenology of premenstrual syndrome in female medical students: a cross sectional study. Pan Afr Med J 2010; 23 (5): 4.
12. Johnson SR. The epidemiology and social impact of premenstrual symptoms. Clin Obstet Gynecol 1987; 30 (2): 367–76.
13. Bancroft J. The menstrual cycle and the well being of women. Soc Sci Med 1995; 41 (6): 785–91.
14. Heinemann LA et al. Intercountry assessment of the impact of severe premenstrual disorders on work and daily activities. Health Care Women Int 2012; 33 (2): 109–24.
15. Kollipaka R, Arounassalame B, Lakshminarayanan S. Does psychosocial stress influence menstrual abnormalities in medical students? J Obstet Gynaecol 2013; 33 (5): 489–93.
16. Delara M, Ghofranipour F, Azadfallah P et al. Health related quality of life among adolescents with premenstrual disorders: a cross sectional study. Health Qual Life Outcomes 2012; 1 (10): 1.
17. Steiner M, Haskett RF, Carroll BJ. Premenstrual tension syndrome: the development of research diagnostic criteria and new rating scales. Acta Psychiatr Scand 1980; 62 (2): 177–90.
18. Ware JE, Sherbourne CD. The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care 1992; 30 (6): 473–83.
19. Moolenaar LM et al. Economic evaluation studies in reproductive medicine: a systematic review of methodologic quality. Fertil Steril 2013; 99 (6): 1689–94.
________________________________________________
1. Prilepskaya VN, Ledina AV, Tagiyeva AV, Revazova FS. Vitex agnus castus: Successful treatment of severe premenstrual syndrome. Maturitas 2006; 55 (1): s55–s63.
2. Halbreich U, Monacelli E. Some clues to the etiology of premenstrual syndrome/premenstrual dysphoric disorder. Prim Psychiatry 2004; 11: 33–40.
3. Kikuchi H, Nakatani Y, Seki Y. Decreased blood serotonin in the premenstrual phase enhances negative mood in healthy women. J Psychosom Obstet Gynaecol 2010; 31 (2): 83–9.
4. Rapkin AJ, Mikacich JA. Premenstrual dysphoric disorder and severe premenstrual syndrome in adolescents. Paediatr Drugs 2013; 15 (3): 191–202.
5. Ware JE, Snow KK, Kosinski M et al. SF-36 Health Survey. Manual and n interpretation guide. The Health Institute. New England Medical Center. Boston, 1993: p. 159.
6. Headey B, Wearing A. Coping with the social environment: the relationship between life events, coping strategies and psychological distress. Community Health Study 1988; 12 (4): 444–52.
7. Nuckols TK, Escarce JJ, Asch SM. The effects of quality of care on costs: a conceptual framework. Milbank Q 2013; 91 (2): 316–53.
8. Salek MS et al. J Drug Dev 1992; 5 (3): 137.
9. Chawla A, Swindle R, Long S et al. Premenstrual dysphoric disorder: is there an economic burden of illness? Med Care 2002; 40 (11): 1101–12.
10. Halbreich U. The etiology, biology, and evolving pathology of premenstrual syndromes – Psychoneuroendocrinology 2003; 28 (3): 55–99.
11. Balaha MH et al. The phenomenology of premenstrual syndrome in female medical students: a cross sectional study. Pan Afr Med J 2010; 23 (5): 4.
12. Johnson SR. The epidemiology and social impact of premenstrual symptoms. Clin Obstet Gynecol 1987; 30 (2): 367–76.
13. Bancroft J. The menstrual cycle and the well being of women. Soc Sci Med 1995; 41 (6): 785–91.
14. Heinemann LA et al. Intercountry assessment of the impact of severe premenstrual disorders on work and daily activities. Health Care Women Int 2012; 33 (2): 109–24.
15. Kollipaka R, Arounassalame B, Lakshminarayanan S. Does psychosocial stress influence menstrual abnormalities in medical students? J Obstet Gynaecol 2013; 33 (5): 489–93.
16. Delara M, Ghofranipour F, Azadfallah P et al. Health related quality of life among adolescents with premenstrual disorders: a cross sectional study. Health Qual Life Outcomes 2012; 1 (10): 1.
17. Steiner M, Haskett RF, Carroll BJ. Premenstrual tension syndrome: the development of research diagnostic criteria and new rating scales. Acta Psychiatr Scand 1980; 62 (2): 177–90.
18. Ware JE, Sherbourne CD. The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care 1992; 30 (6): 473–83.
19. Moolenaar LM et al. Economic evaluation studies in reproductive medicine: a systematic review of methodologic quality. Fertil Steril 2013; 99 (6): 1689–94.
Авторы
А.В.Ледина
ФГБУ Научный центр акушерства, гинекологии и перинатологии им. акад. В.И.Кулакова Минздрава России, Москва
ФГБУ Научный центр акушерства, гинекологии и перинатологии им. акад. В.И.Кулакова Минздрава России, Москва
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A.V.Ledina
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