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Спорные и нерешенные вопросы в терапии кашля у детей в амбулаторной практике
Спорные и нерешенные вопросы в терапии кашля у детей в амбулаторной практике
Геппе Н.А., Малахов А.Б., Зайцева О.В., Дегтярева М.В., Ильенкова Н.А., Калюжин О.В., Карпова Е.П., Ковригина Е.С., Колосова Н.Г., Симонова О.И., Сорока Н.Д., Шуляк И.П., Эткина Э.И. Спорные и нерешенные вопросы в терапии кашля у детей в амбулаторной практике. Педиатрия (Прил. к журн. Consilium Medicum). 2017; 4: 40–45.
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Аннотация
В Москве 30 сентября 2017 г. при поддержке педиатрического респираторного общества состоялось заседание дискуссионного клуба «Спорные и нерешенные вопросы в терапии кашля у детей в амбулаторной практике», объединившее ведущих российских экспертов в области педиатрии, пульмонологии, иммунологии и оториноларингологии. предлагаем вашему вниманию согласованное мнение экспертов.
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Полный текст
Список литературы
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28. Besedina M.V. Atsetiltsistein – novyi «staryi znakomyi». Praktika pediatra. 2007; 5: 64–6. [in Russian]
29. Livingstone CR et al. Model systems for the evaluation of mucolytic drugs: acetylcysteine and S-carboxymethylcysteine. J Pharm Pharmacol 1990; 42 (2): 73–8.
30. Zaitseva O.V. Ratsional'nyi vybor mukoliticheskoi terapii v lechenii boleznei organov dykhaniia u detei. RMZh. 2009; 19: 1217–22. [in Russian]
31. Simonova O.I. Prostye otvety na slozhnye voprosy o mukolitikakh dlia detei. Vopr. sovremen. pediatrii. 2015; 14 (4): 509–13. [in Russian]
32. Ushkalova E.A. Atsetiltsistein v klinicheskoi praktike: nastoiashchee i perspektivy. Farmateka. 2007; 17: 30–6. [in Russian]
33. Aruoma OL, Halliwell B, Hoey BM, Butler J. The antioxidant action of N-acetylcysteine: its reaction with hydrogen peroxide and hypochlorous acid. Free Radic Biol Med 1989; 6 (6): 593–7.
34. Biscatti G, Bruschelli M, Damonte G, Capozzi F. Controlled studies of the clinical effects of acetylcysteine in oral administration in respiratory infections in pediatrics [Ricerca controllata sugli effetti clinici dell’acetilcisteina per via orale nelle infezioni respiratorie in pediatria]. Minerva Pediatrica 1972; 24: 1075–84.
35. Kelly GS. Clinical applications of N-acetylcysteine. Alt Med Rev 1998; 24 (2): 114–27.
36. Macci A, Madeddu C, Panzone F, Mantovani G. Carbocysteine: clinical experience and new perspectives in the treatment of chronic infammatory diseases. Exp Opin Pharmacother 2009; 10 (4): 693–703.
37. Malerba М, Ragnoli В. Ambroxol in the 21st century: pharmacological and clinical update. Exp Opin Drug Metab Toxicol 2008; 4 (8): 1119–29.
38. Ovsiannikov D.Iu., Dukhanin A.S. Mukoaktivnaia terapiia u detei: vzgliad pediatra i farmakologa. Vopr. prakticheskoi pediatrii. 2016; 11 (4): 24–32. [in Russian]
39. Rubin BK. The pharmacologic approach to airway clearance: mucoactive agents. Paediatr Respir Rev 2006; 7 (Suppl. 1): S215–9.
40. Erzurum SC et al. In vivo antioxidant gene expression in human airway epithelium of normal individuals exposed to 100% O2. J Appl Physiol Bethesda Md (1985) 1993; 75 (3): 1256–62.
41. Samuni Y, Goldstein S, Dean О, Berk М. The chemistry and biological activities of N-acetylcysteine. Biochim Biophys Acta 2013; 1830 (8): 4117–29.
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43. Gillissen A. Anti-inflammatory efficacy of N-acetylcysteine and therapeutic usefulness. Pneumologie 2011; 65 (9): 549–57.
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Авторы
Н.А.Геппе1, А.Б.Малахов1, О.В.Зайцева2, М.В.Дегтярева3, Н.А.Ильенкова4, О.В.Калюжин1, Е.П.Карпова5, Е.С.Ковригина3, Н.Г.Колосова1, О.И.Симонова1,6, Н.Д.Сорока7,8, И.П.Шуляк9, Э.И.Эткина10
1 ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М.Сеченова» Минздрава России. 119991, Россия, Москва, ул. Трубецкая, д. 8, стр. 2;
2 ФГБОУ ВО «Московский государственный медико-стоматологический университет им. А.И.Евдокимова» Минздрава России. 127473, Россия, Москва, ул. Делегатская, д. 20, стр. 1;
3 ФГБОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И.Пирогова» Минздрава России. 117997, Россия, Москва, ул. Островитянова, д. 1;
4 ФГБОУ ВО «Красноярский государственный медицинский университет им. проф. В.Ф.Войно-Ясенецкого» Минздрава России. 660022, Россия, Красноярск, ул. Партизана Железняка, д. 1;
5 ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России. 125993, Россия, Москва, ул. Баррикадная, д. 2/1;
6 ФГАУ «Национальный медицинский исследовательский центр здоровья детей» Минздрава России. 119991, Россия, Москва, Ломоносовский пр-т, д. 2, стр. 1;
7 ФГБОУ ВО «Северо-Западный государственный медицинский университет им. И.И.Мечникова» Минздрава России. 191015, Россия, Санкт-Петербург, ул. Кирочная, д. 41;
8 ФГБОУ ВО «Первый Санкт-Петербургский государственный медицинский университет им. акад. И.П.Павлова» Минздрава России. 197022, Россия, Санкт-Петербург, ул. Льва Толстого, д. 6/8;
9 ГБУЗ СО «Областная детская клиническая больница №1». 620149, Россия, Екатеринбург, ул. С.Дерябиной, д. 32;
10 ФГБОУ ВО «Башкирский государственный медицинский университет» Минздрава России. 450008, Россия, республика Башкортостан, Уфа, ул. Ленина, д. 3
1 I.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation. 119991, Russian Federation, Moscow, ul. Trubetskaia, d. 8, str. 2;
2 A.I.Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Health of the Russian Federation. 127473, Russian Federation, Moscow, ul. Delegatskaia, d. 20, str. 1;
3 N.I.Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation. 117997, Russian Federation, Moscow, ul. Ostrovitianova, d. 1;
4 Prof. V.F.Voino-Yasenetski Krasnoyarsk State Medical University of the Ministry of Health of the Russian Federation. 660022, Russian Federation, Krasnoyarsk, ul. Partizana Zhelezniaka, d. 1;
5 Russian Medical Academy of Continuous Professional Education of the Ministry of Health of the Russian Federation. 125993, Russian Federation, Moscow, ul. Barrikadnaia, d. 2/1;
6 National Medical Research Center of Children's Health of the Ministry of Health of the Russian Federation. 119991, Russia, Moscow, Lomonosovsky pr-t, d. 2, str. 1;
7 I.I.Mechnikov State Northwestern Medical University of the Ministry of Health of the Russian Federation. 191015, Russian Federation, Saint Petersburg, ul. Kirochnaia, d. 41;
8 I.P.Pavlov First Saint Petersburg State Medical University of the Ministry of Health of the Russian Federation. 197022, Russian Federation, Saint Petersburg, ul. L'va Tolstogo, d. 6/8;
9 Regional Children's Clinical Hospital №1. 620149, Russian Federation, Ekaterinburg, ul. S.Deriabinoi, d. 32;
10 Bashkir State Medical University. 450008, Russian Federation, Bashkortostan republic, Ufa, ul. Lenina, d. 3
1 ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М.Сеченова» Минздрава России. 119991, Россия, Москва, ул. Трубецкая, д. 8, стр. 2;
2 ФГБОУ ВО «Московский государственный медико-стоматологический университет им. А.И.Евдокимова» Минздрава России. 127473, Россия, Москва, ул. Делегатская, д. 20, стр. 1;
3 ФГБОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И.Пирогова» Минздрава России. 117997, Россия, Москва, ул. Островитянова, д. 1;
4 ФГБОУ ВО «Красноярский государственный медицинский университет им. проф. В.Ф.Войно-Ясенецкого» Минздрава России. 660022, Россия, Красноярск, ул. Партизана Железняка, д. 1;
5 ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России. 125993, Россия, Москва, ул. Баррикадная, д. 2/1;
6 ФГАУ «Национальный медицинский исследовательский центр здоровья детей» Минздрава России. 119991, Россия, Москва, Ломоносовский пр-т, д. 2, стр. 1;
7 ФГБОУ ВО «Северо-Западный государственный медицинский университет им. И.И.Мечникова» Минздрава России. 191015, Россия, Санкт-Петербург, ул. Кирочная, д. 41;
8 ФГБОУ ВО «Первый Санкт-Петербургский государственный медицинский университет им. акад. И.П.Павлова» Минздрава России. 197022, Россия, Санкт-Петербург, ул. Льва Толстого, д. 6/8;
9 ГБУЗ СО «Областная детская клиническая больница №1». 620149, Россия, Екатеринбург, ул. С.Дерябиной, д. 32;
10 ФГБОУ ВО «Башкирский государственный медицинский университет» Минздрава России. 450008, Россия, республика Башкортостан, Уфа, ул. Ленина, д. 3
________________________________________________
1 I.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation. 119991, Russian Federation, Moscow, ul. Trubetskaia, d. 8, str. 2;
2 A.I.Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Health of the Russian Federation. 127473, Russian Federation, Moscow, ul. Delegatskaia, d. 20, str. 1;
3 N.I.Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation. 117997, Russian Federation, Moscow, ul. Ostrovitianova, d. 1;
4 Prof. V.F.Voino-Yasenetski Krasnoyarsk State Medical University of the Ministry of Health of the Russian Federation. 660022, Russian Federation, Krasnoyarsk, ul. Partizana Zhelezniaka, d. 1;
5 Russian Medical Academy of Continuous Professional Education of the Ministry of Health of the Russian Federation. 125993, Russian Federation, Moscow, ul. Barrikadnaia, d. 2/1;
6 National Medical Research Center of Children's Health of the Ministry of Health of the Russian Federation. 119991, Russia, Moscow, Lomonosovsky pr-t, d. 2, str. 1;
7 I.I.Mechnikov State Northwestern Medical University of the Ministry of Health of the Russian Federation. 191015, Russian Federation, Saint Petersburg, ul. Kirochnaia, d. 41;
8 I.P.Pavlov First Saint Petersburg State Medical University of the Ministry of Health of the Russian Federation. 197022, Russian Federation, Saint Petersburg, ul. L'va Tolstogo, d. 6/8;
9 Regional Children's Clinical Hospital №1. 620149, Russian Federation, Ekaterinburg, ul. S.Deriabinoi, d. 32;
10 Bashkir State Medical University. 450008, Russian Federation, Bashkortostan republic, Ufa, ul. Lenina, d. 3
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