Клинические особенности псориаза у детей и подростков
DOI: 10.26442/2413-8460_2018.2.83-88
________________________________________________
Adaskevich V.P., Katina М.А. Clinical peculiarities of psoriasis in children and adolescents. Pediatrics (Suppl. Consilium Medicum). 2018; 2: 83–88.
DOI: 10.26442/2413-8460_2018.2.83-88
Материалы доступны только для специалистов сферы здравоохранения. Авторизуйтесь или зарегистрируйтесь.
Ключевые слова: псориаз, дети, клинические особенности, клинические формы, местная терапия, системная терапия.
________________________________________________
Psoriasis in children is registered in 0.5–2% of cases with increasing incidence trends in recent years. Diagnosing psoriasis in pediatric population is a challenge for dermatologists in many cases. A positive family history is more often reported in children with psoriasis, the face, skin folds and anogenital region are also more often affected in their cases. A typical manifestation of psoriasis in children <2 years of age is neonatal psoriatic diaper dermatitis. Such clinical manifestations of the disease as linear and follicular psoriasis are also more often seen in pediatric population, while severe forms of arthropathic, erythrodermic, pustular psoriasis are rarely encountered. Children and adolescents with moderate psoriasis suffer from adiposis also much more often than general population. At present there are no international guidelines for treatment of childhood psoriasis. Treatment approaches are similar to those for adults but there are insufficient clinical observations concerning efficiency and safety for a number of medicines administered to children. We observed 49 children with psoriasis aged from 1 to 16 years (m=10.3±4.14), they were 28 (58%) girls and 21 (42%) boys. The ratio of girls to boys constituted 1.3:1. The mean age of girls and boys was 7.5±3.9 and 10.1±4.2, respectively. The most numerous group was presented by children aged from 12 to 16 (31%). The positive family history was revealed in 50% of children. The following anatomic locations in children and adolescents were most frequently involved: facial skin (38%), ears and retroauricular areas (60%), anogenital area (32%) and skin folds (45%); the combined involvement of anogenital and intertriginous areas were not infrequently seen (30%). Plaque psoriasis was the most frequent clinical form of the disease in children and adolescents (67%). Guttate psoriasis was diagnosed in 10% of children. Scalp psoriasis was found in 81% of children and in 31% of them it was the initial location of the psoriatic process.
Key words: psoriasis, children, clinical peculiarities, topical treatment, systemic treatment.
2. Bhutani T, Faranak K, Cordoro KM. Management of Pediatric Psoriasis. Pediatric Annals 2012; 41 (1): e11–e17.
3. Bertelsen T, Iversen L. Systemic Treatment of Psoriasis in Children. J Clin Exp Dermatol Res 2015: 6: 6.
4. Helen T. Shin. Diagnosis and management of diaper dermatitis. Pediatr Clin N Am 2014; 61: 367–82.
5. Jager MEA, de Jong EM, van de Kerkhof PC, Seyger MMJ. Psoriasis in Children and Adolescents: Diagnosis, Management and Comorbidities Am Acad Dermatol 2010; 62: 1013–30.
6. Carrie C.Coughlin, Lawrence F.Eichenfield, Frieden Ilona J. Diaper Dermatitis: Clinical Characteristics and Differential Diagnosis. Pediatr Dermatol 2014; l: 19–24.
7. Cohen B. Differential Diagnosis of Diaper Dermatitis. Clin Pediatr 2017; 56 (5): 16–22.
8. Tollefson MM, Crowson CS, McEvoy MT, Maradit Kremers H. Incidence of psoriasis in children: a population-based study. J Am Acad Dermatol 2010; 62 (6): 979–87.
9. Stefanaki C et al. Psoriasis in children: a retrospective analysis JEADV 2011; 25: 417–21.
10. Phiske MM. Scalp Psoriasis: A Brief Overview. J Cosmo Trichol 2016; 2: 2.
11. Pourchot D et al. Nail Psoriasis: A Systematic Evaluation in 313 Children with Psoriasis. Pediatr Dermatol 2016; 1–6.
12. Ravelli A, Consolaro A, Schiappapietra B, Martini A. The conundrum of juvenile psoriatic arthritis Clin Exp Rheumatol 2015; 33: 40–3.
13. Liao PB, Rubinson R, Howard R et al. Annular pustular psoriasis – most common form of pustular psoriasis in children: report of three cases and review of the literature. Pediatr Dermatol 2002; 19 (1): 19–25.
14. Kim AP Meeuwis et al. Genital Psoriasis: A Systematic Literature Review on this Hidden Skin Disease. Acta Derm Venereol 2011; 91: 5–11.
15. Napolitano M et al. Systemic Treatment of Pediatric Psoriasis: A Review. Dermatol Ther (Heidelb) 2016; 6 (2): 125–42.
________________________________________________
1. Bronckers IMGJ et al. Psoriasis in Children and Adolescents: Diagnosis, Management and Comorbidities Pediatr Drugs 2015; 17: 373–84.
2. Bhutani T, Faranak K, Cordoro KM. Management of Pediatric Psoriasis. Pediatric Annals 2012; 41 (1): e11–e17.
3. Bertelsen T, Iversen L. Systemic Treatment of Psoriasis in Children. J Clin Exp Dermatol Res 2015: 6: 6.
4. Helen T. Shin. Diagnosis and management of diaper dermatitis. Pediatr Clin N Am 2014; 61: 367–82.
5. Jager MEA, de Jong EM, van de Kerkhof PC, Seyger MMJ. Psoriasis in Children and Adolescents: Diagnosis, Management and Comorbidities Am Acad Dermatol 2010; 62: 1013–30.
6. Carrie C.Coughlin, Lawrence F.Eichenfield, Frieden Ilona J. Diaper Dermatitis: Clinical Characteristics and Differential Diagnosis. Pediatr Dermatol 2014; l: 19–24.
7. Cohen B. Differential Diagnosis of Diaper Dermatitis. Clin Pediatr 2017; 56 (5): 16–22.
8. Tollefson MM, Crowson CS, McEvoy MT, Maradit Kremers H. Incidence of psoriasis in children: a population-based study. J Am Acad Dermatol 2010; 62 (6): 979–87.
9. Stefanaki C et al. Psoriasis in children: a retrospective analysis JEADV 2011; 25: 417–21.
10. Phiske MM. Scalp Psoriasis: A Brief Overview. J Cosmo Trichol 2016; 2: 2.
11. Pourchot D et al. Nail Psoriasis: A Systematic Evaluation in 313 Children with Psoriasis. Pediatr Dermatol 2016; 1–6.
12. Ravelli A, Consolaro A, Schiappapietra B, Martini A. The conundrum of juvenile psoriatic arthritis Clin Exp Rheumatol 2015; 33: 40–3.
13. Liao PB, Rubinson R, Howard R et al. Annular pustular psoriasis – most common form of pustular psoriasis in children: report of three cases and review of the literature. Pediatr Dermatol 2002; 19 (1): 19–25.
14. Kim AP Meeuwis et al. Genital Psoriasis: A Systematic Literature Review on this Hidden Skin Disease. Acta Derm Venereol 2011; 91: 5–11.
15. Napolitano M et al. Systemic Treatment of Pediatric Psoriasis: A Review. Dermatol Ther (Heidelb) 2016; 6 (2): 125–42.
УО «Витебский государственный медицинский университет». 210023, Беларусь, Витебск, пр. Фрунзе, д. 27
*uladas@hotmail.com
________________________________________________
V.P.Adaskevich*, М.А.Katina
Vitebsk State Medical University. 210023, Belarus, Vitebsk, pr. Frunze, d. 27
*uladas@hotmail.com