Новая коронавирусная инфекция в детском возрасте: обзор литературы и клиническое наблюдение

Малахов А.Б., Гутырчик Т.А., Самитова Э.Р. и др. Новая коронавирусная инфекция в детском возрасте: обзор литературы и клиническое наблюдение. Педиатрия. Consilium Medicum. 2020; 4: 31–37. DOI: 10.26442/26586630.2020.4.200560

________________________________________________

Malakhov A.B., Gutyrchik T.A., Samitova E.R. et al. Novel coronavirus infection in childhood: literature review and clinical observation. Pediatrics. Consilium Medicum. 2020; 4: 31–37. DOI: 10.26442/26586630.2020.4.200560

Читать PDF

Аннотация

В статье представлены обзор литературы и клиническое наблюдение случая тяжелой формы новой коронавирусной инфекции COVID-19 у ребенка 8 лет, которая осложнилась бактериальной инфекцией. Актуальность данного клинического случая связана с новизной самого заболевания, относительной редкостью тяжелой формы новой коронавирусной инфекции в детском возрасте, сложностью ее лечения, сочетанием вирусного и бактериального воспаления нижних дыхательных путей.

Ключевые слова: новая коронавирусная инфекция, COVID-19, дети.

________________________________________________

The article presents a review of the literature and a clinical observation of a case of a severe form of the new coronavirus infection COVID-19 in an 8-year-old child, which was complicated by a bacterial infection. The relevance of this clinical case is associated with the novelty of the disease itself, the relative rarity of a severe form of a new coronavirus infection in childhood, the complexity of its treatment, and a combination of viral and bacterial inflammation of the lower respiratory tract.

Key words: new coronavirus infection, COVID-19, children.

Полный текст

Материалы доступны только для специалистов сферы здравоохранения.
Чтобы посмотреть материал полностью Авторизуйтесь или зарегистрируйтесь.

Список литературы

1. World Health Organization (WHO). Pneumonia of unknown cause – China. 2020. https://www.who.int/csr/don/05-january-2020-pneumonia-of-unkown-cause-china/en/
2. World Health Organization (WHO). Coronavirus disease 2019 (COVID-19) situation reports. https://www.who.int/emergencies/diseases/novel-coronavirus-2019/situation-reports
3. Available from: https://systems.jhu.edu/research/public-health/ncov/
4. World Health Organization (WHO). Coronavirus disease (COVID-19) pandemic. https://www.who.int/emergencies/diseases/novel-coronavirus-2019
5. Информация о случаях пневмонии, вызванной 2019-nCOV. https://www.rospotrebnadzor.ru/region/korono_virus/epid.php
[Informatsiia o sluchaiakh pnevmonii, vyzvannoi 2019-nCOV. https://www.rospotrebnadzor.ru/region/korono_virus/epid.php (in Russian).]
6. Dong Y, Mo X, Hu Y et al. Epidemiology of COVID-19 Among Children in China. Pediatrics 2020; 145 (6): e20200702.
7. The Novel Coronavirus Pneumonia Emergency Response Epidemiology Team. The Epidemiological Characteristics of an Outbreak of 2019 Novel Coronavirus Diseases (COVID-19) – China, 2020. China CDC Weekly 2020; 2 (8): 113–22.
8. Liu W, Zhang Q, Chen J et al. Detection of COVID-19 in Children in Early January 2020 in Wuhan, China. N Engl J Med 2020; 382 (14): 1370–1.
9. Li W, Moore MJ, Vasilieva N, et al. Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus. Nature 2003; 426 (6965): 450–4.
10. Zhou P, Yang X, Wang X et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature 2020; 579 (7798): 270–3.
11. Wrapp D, Wang N, Corbett K et al. Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation. Science 2020; 13; 367 (6483): 1260–3.
12. Fang F, Lu X. Facing the pandemic of 2019 novel coronavirus infections: the pediatric perspectives. Chinese J Pediatrics 2020; 2; 58 (0): E001.
13. Grifoni A, Weiskopf D, Ramirez SI et al. Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals. Cell 2020; 25; 181 (7): 1489–501.e15.
14. Методические рекомендации особенности клинических проявлений и лечения заболевания, вызванного новой коронавирусной инфекции (COVID-19) у детей. Версия 2 (03.07.2020); утв. Минздравом России.
[Methodical recommendations on the features of clinical manifestations and treatment of the disease caused by a new coronavirus infection (COVID-19) in children. Version 2 (07.03.2020); approved by the Ministry of Health of Russia (in Russian).]
15. Multisystem inflammatory syndrome in children and adolescents temporally related to COVID-19 WHO, Scientific Brief, 15 May 2020.

________________________________________________

1. World Health Organization (WHO). Pneumonia of unknown cause – China. 2020. https://www.who.int/csr/don/05-january-2020-pneumonia-of-unkown-cause-china/en/
2. World Health Organization (WHO). Coronavirus disease 2019 (COVID-19) situation reports. https://www.who.int/emergencies/diseases/novel-coronavirus-2019/situation-reports
3. Available from: https://systems.jhu.edu/research/public-health/ncov/
4. World Health Organization (WHO). Coronavirus disease (COVID-19) pandemic. https://www.who.int/emergencies/diseases/novel-coronavirus-2019
5. Информация о случаях пневмонии, вызванной 2019-nCOV. https://www.rospotrebnadzor.ru/region/korono_virus/epid.php
[Informatsiia o sluchaiakh pnevmonii, vyzvannoi 2019-nCOV. https://www.rospotrebnadzor.ru/region/korono_virus/epid.php (in Russian).]
6. Dong Y, Mo X, Hu Y et al. Epidemiology of COVID-19 Among Children in China. Pediatrics 2020; 145 (6): e20200702.
7. The Novel Coronavirus Pneumonia Emergency Response Epidemiology Team. The Epidemiological Characteristics of an Outbreak of 2019 Novel Coronavirus Diseases (COVID-19) – China, 2020. China CDC Weekly 2020; 2 (8): 113–22.
8. Liu W, Zhang Q, Chen J et al. Detection of COVID-19 in Children in Early January 2020 in Wuhan, China. N Engl J Med 2020; 382 (14): 1370–1.
9. Li W, Moore MJ, Vasilieva N, et al. Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus. Nature 2003; 426 (6965): 450–4.
10. Zhou P, Yang X, Wang X et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature 2020; 579 (7798): 270–3.
11. Wrapp D, Wang N, Corbett K et al. Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation. Science 2020; 13; 367 (6483): 1260–3.
12. Fang F, Lu X. Facing the pandemic of 2019 novel coronavirus infections: the pediatric perspectives. Chinese J Pediatrics 2020; 2; 58 (0): E001.
13. Grifoni A, Weiskopf D, Ramirez SI et al. Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals. Cell 2020; 25; 181 (7): 1489–501.e15.
14. [Methodical recommendations on the features of clinical manifestations and treatment of the disease caused by a new coronavirus infection (COVID-19) in children. Version 2 (07.03.2020); approved by the Ministry of Health of Russia (in Russian).]
15. Multisystem inflammatory syndrome in children and adolescents temporally related to COVID-19 WHO, Scientific Brief, 15 May 2020.

Авторы

А.Б. Малахов 1,2*, Т.А. Гутырчик 2, Э.Р. Самитова 3, И.А. Дронов 1, И.М. Османов 3, Л.Н. Мазанкова 3,4, А.А. Недостоев 3, М.А. Анцупова 3, Н.Г.Колосова 1

1 ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский Университет), Москва, Россия;
2 ГБУЗ «Морозовская детская городская клиническая больница» Департамента здравоохранения г. Москвы, Москва, Россия;
3 ГБУЗ «Детская городская клиническая больница им. З.А. Башляевой» Департамента здравоохранения г. Москвы, Москва, Россия;
4 ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России, Москва, Россия
alexis4591m@mail.ru

________________________________________________

Aleksandr B. Malakhov 1,2*, Tatiana A. Gutyrchik 2, Elmira R. Samitova 3, Ivan A. Dronov 1, Ismail M. Osmanov 3, Liudmila N. Mazankova 3,4, Aleksei A. Nedostoev 3, Margarita A. Antsupova 3, Natalia G. Kolosova 1

1 Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia;
2 Morozov Children's Clinical Hospital, Moscow, Russia;
3 Bashlyaeva Children's City Clinical Hospital. Moscow, Russia;
4 Russian Medical Academy of Continuous Professional Education, Moscow, Russia

*alexis4591m@mail.ru

Назад к списку

Цель портала OmniDoctor – предоставление профессиональной информации врачам, провизорам и фармацевтам.