Общие и частные вопросы этиопатогенеза язвенной болезни и рака желудка: современное состояние проблемы
Общие и частные вопросы этиопатогенеза язвенной болезни и рака желудка: современное состояние проблемы
Осадчук А.М., Давыдкин И.Л., Гриценко Т.А., Осадчук М.А. Общие и частные вопросы этиопатогенеза язвенной болезни и рака желудка: современное состояние проблемы. Терапевтический архив. 2020; 92 (2): 97–103. DOI: 10.26442/00403660. 2020.02.000485
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Аннотация
Развитие язвенной болезни (ЯБ) и рака желудка (РЖ) является результатом взаимодействия различных внутренних и внешних факторов. При этом если роль Helicobacter pylori (H. pylori) в развитии заболеваний желудка полностью установлена, то значение многих других факторов продолжает обсуждаться. Серьезные споры вызывает участие различных штаммов H. pylori в развитии ЯБ и РЖ. Прежде всего это Vac- и Cag-позитивные штаммы H. pylori. Дискуссионной является роль генетического полиморфизма человека в развитии данной патологии, особенно генов интерлейкинов и фактора некроза опухоли α. Не в полной мере понятна роль средовых факторов в формировании ЯБ и РЖ. Так, продолжает обсуждаться роль алкоголя, профессиональных вредностей и лекарственных препаратов в развитии этих заболеваний. Дальнейшее исследование факторов риска различных заболеваний желудка позволит оптимизировать их профилактику и лечение. В обзоре представлен современный взгляд на отдельные вопросы патогенезе ЯБ и РЖ.
Ключевые слова: Helicobacter pylori, язвенная болезнь, рак желудка, генетические факторы человека, средовые факторы.
Keywords: Helicobacter pylori, peptic ulcer, stomach cancer, human genetic factors, environmental factors.
Ключевые слова: Helicobacter pylori, язвенная болезнь, рак желудка, генетические факторы человека, средовые факторы.
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Keywords: Helicobacter pylori, peptic ulcer, stomach cancer, human genetic factors, environmental factors.
Список литературы
1. Маев И.В., Кучерявый Ю.А., Андреев Д.Н., Баркалова Е.В. Эрадикационная терапия инфекции Helicobacter pylori: обзор мировых тенденций. Терапевтический архив. 2014;86(3):94-9 [Maev IV, Kucheryavyi YuA, Andreev DN, Barkalova EV. Eradication therapy for Helicobacter pylori infection: review of world trends. Therapeutic Archive. 2014;86(3):94-9 (In Russ.)].
2. Маев И.В., Андреев Д.Н. Молекулярно-генетические предикторы резистентности к антихеликобактерной терапии. Терапевтический архив. 2017;89(8):5-12 [Maev IV, Andreev DN. Molecular genetic predictors of resistance to anti-Helicobacter pylori therapy. Therapeutic Archive. 2017;89(8):5-12 (In Russ.)]. doi: 10.17116/terarkh20178985-12
3. Андреев Д.Н., Дичева Д.Т., Маев И.В. Возможности оптимизации эрадикационной терапии инфекции Helicobacter pylori в современной клинической практике. Терапевтический архив. 2017;89(2):84-90 [Andreev DN, Dicheva DT, Maev IV. Possibilities for optimization of eradication therapy for Helicobacter pylori infection in modern clinical practice. Therapeutic Archive. 2017;89(2):84-90 (In Russ.)]. doi: 10.17116/terarkh201789284-90
4. Chang WL, Yeh YC, Sheu BS. The impacts of H. pylori virulence factors on the development of gastroduodenal diseases. J Biomed Sci. 2018 Sep 11;25(1):68. doi: 10.1186/s12929-018-0466-9
5. Kwok T, Zabler D, Urman S, Rohde M, Hartig R, Wessler S, et al. Helicobacter exploits integrin for type IV secretion and kinase activation. Nature. 2007;449(7164):862-6. doi: 10.1038/nature06187
6. Hayashi Y, Tsujii M, Wang J, Kondo J, Akasaka T, Jin Y, et al. CagA mediates epigenetic regulation to attenuate let-7 expression in Helicobacter pylori-related carcinogenesis. Gut. 2013;62(11):1536-46. doi: 10.1136/gutjnl-2011-301625
7. Huang JQ, Zheng GF, Sumanac K, Irvine EJ, Hunt RH. Meta-analysis of the relationship between cagA seropositivity and gastric cancer. Gastroenterology. 2003 Dec;125(6):1636-44.
8. Yeh YC, Chang WL, Yang HB, Cheng HC, Wu JJ, Sheu BS. H. pylori cagL amino acid sequence polymorphism Y58E59 induces a corpus shift of gastric integrin α5β1 related with gastric carcinogenesis. Mol Carcinog. 2011 Oct;50(10):751-9. doi: 10.1002/mc.20753
9. Li Q, Liu J, Gong Y, Yuan Y. Association of CagA EPIYA-D or EPIYA-C phosphorylation sites with peptic ulcer and gastric cancer risks: a meta-analysis. Medicine (Baltimore). 2017;96(17):e6620. doi: 10.1097/MD.0000000000006620
10. Zhang X-S, Tegtmeyer N, Traube L, Jindal S, Perez-Perez G, Backert S, Blaser MJ. A specific A/T polymorphism in western tyrosine phosphorylation b-motifs regulates helicobacter pylori caga epithelial cell interactions. PLoS Pathog. 2015 Feb;11(2):e1004621. doi: 10.1371/journal.ppat.1004621
11. Delchier JC, Lamarque D, Levy M, Tkoub EM, Copie-Bergman C, Deforges L, et al. Helicobacter pylori and gastric lymphoma: high seroprevalence of CagA in diffuse large B-cell lymphoma but not in low-grade lymphoma of mucosa-associated lymphoid tissue type. Am J Gastroenterol. 2001;96(8):2324-8. doi: 10.1111/j.1572-0241.2001.04036.x
12. Kuo SH, Yeh KH, Chen LT, Lin CW, Hsu PN, Wu MS, et al. Helicobacter pylori CagA translocation is closely associated with the expression of CagA-signaling molecules in low-grade gastric mucosa-associated lymphoid tissue lymphoma. Am J Surg Pathol. 2015;39(6):761-6. doi: 10.1097/PAS.0000000000000437
13. Matos JI, de Sousa HA, Marcos-Pinto R, Dinis-Ribeiro M. Helicobacter pylori CagA and VacA genotypes and gastric phenotype: a meta-analysis. Eur J Gastroenterol Hepatol. 2013 Dec;25(12):1431-41. doi: 10.1097/MEG.0b013e328364b53e
14. Liu X, He B, Cho WC, Pan Y, Chen J, Ying H, et al. A systematic review on the association between the Helicobacter pylori vacA I genotype and gastric disease. FEBS Open Bio. 2016;6(5):409-17. doi: 10.1002/2211-5463.12046
15. Gonzalez CA, Figueiredo C, Lic CB, Ferreira RM, Pardo ML, Ruiz Liso JM, et al. Helicobacter pylori cagA and vacA genotypes as predictors of progression of gastric preneoplastic lesions: a long-term follow-up in a high-risk area in Spain. Am J Gastroenterol. 2011;106(5):867-74. doi: 10.1038/ajg.2011.1
16. Sugimoto M, Yamaoka Y. The association of vacA genotype and Helicobacter pylori-related disease in Latin American and African populations. Clin Microbiol Infect. 2009;15(9):835-42. doi: 10.1111/j.1469-0691.2009.02769.x
17. Sahara S, Sugimoto M, Vilaichone RK, Mahachai V, Miyajima H, Furuta T, et al. Role of Helicobacter pylori cagA EPIYA motif and vacA genotypes for the development of gastrointestinal diseases in Southeast Asian countries: a meta-analysis. BMC Infect Dis. 2012;12:223. doi: 10.1186/1471-2334-12-223
18. Yeh YC, Kuo HY, Chang WL,Yang HB, Lu CC, Cheng HC, et al. H. pylori isolates with amino acid sequence polymorphisms as presence of both HtrA-L171 & CagL-Y58/E59 increase the risk of gastric cancer. J Biomed Sci. 2019 Jan 5;26(1):4. doi: 10.1186/s12929-019-0498-9
19. Hussein NR. The association of dupA and Helicobacter pylori-related gastroduodenal diseases. Eur J Clin Microbiol Infect Dis. 2010;29(7):817-21. doi: 10.1007/s10096-010-0933-z
20. Shiota S, Matsunari O, Watada M, Hanada K, Yamaoka Y. Systematic review and meta-analysis: the relationship between the Helicobacter pylori dupA gene and clinical outcomes. Gut Pathog. 2010;2(1):13. doi: 10.1186/1757-4749-2-13
21. Jung SW, Sugimoto M, Shiota S, Graham DY, Yamaoka Y. The intact dupA cluster is a more reliable Helicobacter pylori virulence marker than dupA alone. Infect Immun. 2012;80(1):381-7. doi: 10.1128/IAI.05472-11
22. Fujimoto S, Olaniyi OO, Arnqvist A, Wu JY, Odenbreit S, Haas R, et al. Helicobacter pylori BabA expression, gastric mucosal injury, and clinical outcome. Clin Gastroenterol Hepatol. 2007;5(1):49-58. doi: 10.1016/j.cgh.2006.09.015
23. Gerhard M, Lehn N, Neumayer N, Borén T, Rad R, Schepp W, et al. Clinical relevance of the Helicobacter pylori gene for blood-group antigen-binding adhesin. Proc Natl Acad Sci U S A. 1999;96(22):12778-83. doi: 10.1073/pnas.96.22.12778
24. Chen MY, He CY, Meng X, Yuan Y. Association of Helicobacter pylori babA2 with peptic ulcer disease and gastric cancer. World J Gastroenterol. 2013;19(26):4242-51. doi: 10.3748/wjg.v19.i26.4242
25. Su YL, Huang HL, Huang BS, Chen PC, Chen CS, Wang HL, et al. Combination of OipA, BabA, and SabA as candidate biomarkers for predicting Helicobacter pylori-related gastric cancer. Sci Rep. 2016 Nov 7;6:36442. doi: 10.1038/srep36442
26. Peek RM Jr, Thompson SA, Donahue JP, Tham KT, Atherton JC, Blaser MJ, Miller GG. Adherence to gastric epithelial cells induces expression of a Helicobacter pylori gene, iceA, that is associated with clinical outcome. Proc Assoc Am Physicians. 1998;110(6):531-44.
27. Shiota S, Watada M, Matsunari O, Iwatani S, Suzuki R, Yamaoka Y. Helicobacter pylori iceA, clinical outcomes, and correlation with cagA: a meta-analysis. PLoS One. 2012;7(1):e30354. doi: 10.1371/journal.pone.0030354
28. Dossumbekova A, Prinz C, Mages J, Lang R, Kusters JG, Vliet AH, et al. Helicobacter pylori HopH (OipA) and bacterial pathogenicity: genetic and functional genomic analysis of hopH gene polymorphisms. J Infect Dis. 2006;194(10):1346-55. doi: 10.1086/508426
29. Liu J, He C, Chen M, Wang Z, Xing C, Yuan Y. Association of presence/absence and on/off patterns of Helicobacter pylori oipA gene with peptic ulcer disease and gastric cancer risks: a meta-analysis. BMC Infect Dis. 2013;13:555. doi: 10.1186/1471-2334-13-555
30. Pakbaz Z, Shirazi MH, Ranjbar R, Reza M, Gholi MK, Aliramezani A, Malekshahi ZV. Frequency of sabA gene in Helicobacter pylori strains isolated from patients in Tehran, Iran. Iran Red Crescent Med J. 2013 Sep;15(9):767-70.
31. Goudarzi H, Rezaee H, Rafizadeh M, Taghav A. Determination of the status of Helicobacter pylori sabA gene in relation to clinical findings. J Med Bacteriol. 2012;1(1, 2):3-8.
32. Ma K, Baloch Z, He T-T, Xia X. Alcohol consumption and gastric cancer risk: A meta-analysis. Med Sci Monit. 2017;23:238-46.
33. Júnior UR, Viscondi JKY, Zilberstein B, Cecconello I, Eluf-Neto J. Risk factors associated with the development of gastric cancer – case-control study. Rev Assoc Med Bras. 2018;64(7):611-9. doi: 10.1590/1806-9282.64.07.611
34. Choi YJ, Myung SK, Lee JH. Light alcohol drinking and risk of cancer: A meta-analysis of cohort studies. Cancer Res Treat. 2018 Apr;50(2):474-87. doi: 10.4143/crt.2017.094
35. Rosenstock S, Jørgensen T, Bonnevie O, Andersen L. Risk factors for peptic ulcer disease: a population based prospective cohort study comprising 2416 Danish adults. Gut. 2003 Feb;52(2):186-93. doi: 10.1136/gut.52.2.186
36. Lin P-Y, Wang J-Yi, Shih D-P., Kuo H-W, Liang W-M. The Interaction Effects of Burnout and Job Support on Peptic Ulcer Disease among Firefighters and Policemen. Int J Environ Res Pub Health. 2019;16(13). pii: E2369. doi: 10.3390/ijerph16132369
37. Abioye AI, Odesanya MO, Abioye AI, Ibrahim NA. Physical activity and risk of gastric cancer: a meta-analysis of observational studies. Br J Sports Med. 2015 Feb;49(4):224-9. doi: 10.1136/bjsports-2013-092778
38. Ordóñez-Mena JM, Schöttker B, Mons U, Jenab M, Freisling H, et al. Quantification of the smoking-associated cancer risk with rate advancement periods: meta-analysis of individual participant data from cohorts of the CHANCES consortium. BMC Med. 2016;14:62. doi: 10.1186/s12916-016-0607-5
39. Yusefi AR, Bagheri Lankarani K, Bastani P, Radinmanesh M, Kavosi Z. Risk Factors for gastric cancer: A systematic review. Asian Pac J Cancer Prev. 2018 Mar 27;19(3):591-603.
40. Campbell PT, Sloan M, Kreiger N. dietary patterns and risk of incident gastric adenocarcinoma. Am J Epidemiol. 2008;167:295-304. doi: 10.1093/aje/kwm294
41. Kim J, Kim KH, Lee BJ. Association of peptic ulcer disease with obesity, nutritional components, and blood parameters in the Korean population. PLoS One. 2017;12(8):e0183777. doi: 10.1371/journal.pone.0183777
42. Edgren G, Hjalgrim H, Rostgaard K, Norda R, Wikman A, Melbye M, Nyrén O. Risk of gastric cancer and peptic ulcers in relation to AB0 blood type: a cohort study. Am J Epidemiol. 2010 Dec 1;172(11):1280-5. doi: 10.1093/aje/kwq299
43. Alkebsi L, Ideno Y, Lee J-S, Suzuki S, Nakajima-Shimada J, Ohnishi H, et al. Gastroduodenal Ulcers and ABO Blood Group: the Japan Nurses’ Health Study (JNHS). J Epidemiol. 2018;28(1):34-40. doi: 10.2188/jea.JE20160204
44. Balakrishnan M, George R, Sharma A, Graham DY. Changing trends in stomach cancer throughout the world. Curr Gastroenterol Rep. 2017;19(8):36. doi: 10.1007/s11894-017-0575-8
45. Sugimoto M, Furuta T, Shirai N, Nakamura A, Xiao F, Kajimura M, et al. Different effects of polymorphisms of tumor necrosis factor-alpha and interleukin-1 beta on development of peptic ulcer and gastric cancer. J Gastroenterol Hepatol. 2007 Jan;22(1):51-9.
46. Zhang J, Dou C, Song Y, Ji C, Gu S, Xie Y, Mao Y. Polymorphisms of tumor necrosis factor-alpha are associated with increased susceptibility to gastric cancer: a meta-analysis. J Hum Genet. 2008;53(6):479-89. doi: 10.1007/s10038-008-0273-3
47. Shibata T, Tahara T, Hirata I, Arisawa T. Genetic polymorphism of interleukin-17A and -17F genes in gastric carcinogenesis. Hum Immunol. 2009 Jul;70(7):547-51. doi: 10.1016/j.humimm.2009.04.030
48. Chakravorty M, Ghosh A, Choudhury A, Santra A, Hembrum J, Roychoudhury S. Interaction between IL1B gene promoter polymorphisms in determining susceptibility to Helicobacter pylori associated duodenal ulcer. Hum Mutat. 2006 May;27(5):411-9.
49. Hold GL, Rabkin CS, Chow WH, Smith MG, Gammon MD, Risch HA, et al. A functional polymorphism of toll-like receptor 4 gene increases risk of gastric carcinoma and its precursors. Gastroenterology. 2007 Mar;132(3):905-12.
50. Kang JM, Kim N, Lee DH, Park JH, Lee MK, Kim JS, et al. The effects of genetic polymorphisms of IL-6, IL-8, and IL-10 on Helicobacter pylori-induced gastroduodenal diseases in Korea. J Clin Gastroenterol. 2009 May-Jun;43(5):420-8. doi: 10.1097/MCG.0b013e318178d1d3
51. Musumba CO, Jorgensen A, Sutton L, Van Eker D, Zhang E, O'Hara N, et al. CYP2C19*17 gain-of-function polymorphism is associated with peptic ulcer disease. Clin Pharmacol Ther. 2013 Feb;93(2):195-203. doi: 10.1038/clpt.2012.215
52. Sugimoto M, Furuta T, Shirai N, Nakamura A, Kajimura M, Sugimura H, et al. Poor metabolizer genotype status of CYP2C19 is a risk factor for developing gastric cancer in Japanese patient s with Helicobacter pylori infection. Aliment Pharmacol Ther. 2005 Nov 15;22(10):1033-40.
53. Tanikawa C, Matsuo K, Kubo M, Takahashi A, Ito H, Tanaka H, et al. Impact of PSCA variation on gastric ulcer susceptibility. PloS One. 2013;8(5):e63698.
54. Kobayashi D, Takahashi O, Arioka H, Tsuguya Fukui T. The optimal screening interval for gastric cancer using esophago-gastro-duodenoscopy in Japan. BMC Gastroenterol. 2012;12:144. doi: 10.1186/1471-230X-12-144
55. Levenstein S, Rosenstock S, Jacobsen RK, Jorgensen T. Psychological stress increases risk for peptic ulcer, regardless of helicobacter pylori infection or use of nonsteroidal anti-inflammatory drugs. Clin Gastroenterol Hepatol. 2015;13:498-506.
56. Suh M, Wikoff D, Lipworth L, Goodman M, Fitch S, Mittal L, et al. Hexavalent chromium and stomach cancer: a systematic review and meta-analysis Crit Rev Toxicol. 2019 Mar;21:1-20. doi: 10.1080/10408444.2019.1578730
57. Sjödahl K, Jansson C, Bergdahl IA, Adami J, Boffetta P, Lagergren J. Airborne exposures and risk of gastric cancer: a prospective cohort study. Int J Cancer. 2007 May 1;120(9):2013-8.
58. Parent M-É, Siemiatycki J, Fritschi L. Occupational exposures and gastric cancer. Epidemiology. 1998;9:48-55.
59. Koh DH, Kim TW, Jang S, Ryu HW. Dust exposure and the risk of cancer in cement industry workers in Korea. Am J Industr Med. 2013;56(3):276-81. doi: 10.1002/ajim.22132
60. Lee W, Ahn YS, Lee S, Song BM, Hong S, Yoon JH. Occupational exposure to crystalline silica and gastric cancer: a systematic review and meta-analysis. Occup Environ Med. 2016 Nov;73(11):794-801. doi: 10.1136/oemed-2016-103552. Epub 2016 Sep 12.
61. Chang CJ, Tu YK, Chen PC, Yang HY. Talc exposure and risk of stomach cancer: Systematic review and meta-analysis of occupational cohort studies. J Formos Med Assoc. 2018 Aug 9. pii: S0929-6646(18)30353-X. doi: 10.1016/j.jfma.2018.07.015
62. Ye W, Chow WH, Lagergren J, Yin L, Nyrén O. Risk of adenocarcinomas of the esophagus and gastric cardia in patients with gastroesophageal reflux diseases and after antireflux surgery. Gastroenterology. 2001 Dec;121(6):1286-93.
63. Lin XJ, Wang CP, Liu XD, Yan KK, Li S, Bao HH, et al. Body mass index and risk of gastric cancer: a meta-analysis. Jpn J Clin Oncol. 2014 Sep;44(9):783-91. doi: 10.1093/jjco/hyu082
64. Kuipers EJ. Pernicious anemia, atrophic gastritis, and the risk of cancer. Clin Gastroenterol Hepatol. 2015;13:2290-2 doi: 10.1016/j.cgh.2015.07.013
65. Morton LM, Dores GM, Curtis RE, Lynch CF, Stovall M, Hall P, et al. Stomach cancer risk after treatment for hodgkin lymphoma. J Clin Oncol. 2013 Sep 20;31(27):3369-77. doi: 10.1200/JCO.2013.50.6832
66. Ohyauchi M, Imatani A, Yonechi M, Asano N, Miura A, Iijima K., Koike T, et al. The polymorphism interleukin 8 −251 A/T influences the susceptibility of Helicobacter pylori related gastric diseases in the Japanese population. Gut. 2005;54(3):330-5.
67. Yin YW, Hu AM, Sun QQ, Zhang BB, Wang Q, Liu HL, et al. Association between interleukin-8 gene −251 T/A polymorphism and the risk of peptic ulcer disease: a meta-analysis. Hum Immunol. 2013;74(1):125-30.
68. Ramis IB, Vianna JS, Gonçalves CV, von Groll A, Dellagostin OA, da Silva PEA. Polymorphisms of the IL-6, IL-8 and IL-10 genes and the risk of gastric pathology in patients infected with Helicobacter pylori. J Microbiol Immunol Infect. 2017 Apr;50(2):153-9. doi: 10.1016/j.jmii.2015.03.002
2. Maev IV, Andreev DN. Molecular genetic predictors of resistance to anti-Helicobacter pylori therapy. Therapeutic Archive. 2017;89(8):5-12 (In Russ.) doi: 10.17116/terarkh20178985-12
3. Andreev DN, Dicheva DT, Maev IV. Possibilities for optimization of eradication therapy for Helicobacter pylori infection in modern clinical practice. Therapeutic Archive. 2017;89(2):84-90 (In Russ.) doi: 10.17116/terarkh201789284-90
4. Chang WL, Yeh YC, Sheu BS. The impacts of H. pylori virulence factors on the development of gastroduodenal diseases. J Biomed Sci. 2018 Sep 11;25(1):68. doi: 10.1186/s12929-018-0466-9
5. Kwok T, Zabler D, Urman S, Rohde M, Hartig R, Wessler S, et al. Helicobacter exploits integrin for type IV secretion and kinase activation. Nature. 2007;449(7164):862-6. doi: 10.1038/nature06187
6. Hayashi Y, Tsujii M, Wang J, Kondo J, Akasaka T, Jin Y, et al. CagA mediates epigenetic regulation to attenuate let-7 expression in Helicobacter pylori-related carcinogenesis. Gut. 2013;62(11):1536-46. doi: 10.1136/gutjnl-2011-301625
7. Huang JQ, Zheng GF, Sumanac K, Irvine EJ, Hunt RH. Meta-analysis of the relationship between cagA seropositivity and gastric cancer. Gastroenterology. 2003 Dec;125(6):1636-44.
8. Yeh YC, Chang WL, Yang HB, Cheng HC, Wu JJ, Sheu BS. H. pylori cagL amino acid sequence polymorphism Y58E59 induces a corpus shift of gastric integrin α5β1 related with gastric carcinogenesis. Mol Carcinog. 2011 Oct;50(10):751-9. doi: 10.1002/mc.20753
9. Li Q, Liu J, Gong Y, Yuan Y. Association of CagA EPIYA-D or EPIYA-C phosphorylation sites with peptic ulcer and gastric cancer risks: a meta-analysis. Medicine (Baltimore). 2017;96(17):e6620. doi: 10.1097/MD.0000000000006620
10. Zhang X-S, Tegtmeyer N, Traube L, Jindal S, Perez-Perez G, Backert S, Blaser MJ. A specific A/T polymorphism in western tyrosine phosphorylation b-motifs regulates helicobacter pylori caga epithelial cell interactions. PLoS Pathog. 2015 Feb;11(2):e1004621. doi: 10.1371/journal.ppat.1004621
11. Delchier JC, Lamarque D, Levy M, Tkoub EM, Copie-Bergman C, Deforges L, et al. Helicobacter pylori and gastric lymphoma: high seroprevalence of CagA in diffuse large B-cell lymphoma but not in low-grade lymphoma of mucosa-associated lymphoid tissue type. Am J Gastroenterol. 2001;96(8):2324-8. doi: 10.1111/j.1572-0241.2001.04036.x
12. Kuo SH, Yeh KH, Chen LT, Lin CW, Hsu PN, Wu MS, et al. Helicobacter pylori CagA translocation is closely associated with the expression of CagA-signaling molecules in low-grade gastric mucosa-associated lymphoid tissue lymphoma. Am J Surg Pathol. 2015;39(6):761-6. doi: 10.1097/PAS.0000000000000437
13. Matos JI, de Sousa HA, Marcos-Pinto R, Dinis-Ribeiro M. Helicobacter pylori CagA and VacA genotypes and gastric phenotype: a meta-analysis. Eur J Gastroenterol Hepatol. 2013 Dec;25(12):1431-41. doi: 10.1097/MEG.0b013e328364b53e
14. Liu X, He B, Cho WC, Pan Y, Chen J, Ying H, et al. A systematic review on the association between the Helicobacter pylori vacA I genotype and gastric disease. FEBS Open Bio. 2016;6(5):409-17. doi: 10.1002/2211-5463.12046
15. Gonzalez CA, Figueiredo C, Lic CB, Ferreira RM, Pardo ML, Ruiz Liso JM, et al. Helicobacter pylori cagA and vacA genotypes as predictors of progression of gastric preneoplastic lesions: a long-term follow-up in a high-risk area in Spain. Am J Gastroenterol. 2011;106(5):867-74. doi: 10.1038/ajg.2011.1
16. Sugimoto M, Yamaoka Y. The association of vacA genotype and Helicobacter pylori-related disease in Latin American and African populations. Clin Microbiol Infect. 2009;15(9):835-42. doi: 10.1111/j.1469-0691.2009.02769.x
17. Sahara S, Sugimoto M, Vilaichone RK, Mahachai V, Miyajima H, Furuta T, et al. Role of Helicobacter pylori cagA EPIYA motif and vacA genotypes for the development of gastrointestinal diseases in Southeast Asian countries: a meta-analysis. BMC Infect Dis. 2012;12:223. doi: 10.1186/1471-2334-12-223
18. Yeh YC, Kuo HY, Chang WL,Yang HB, Lu CC, Cheng HC, et al. H. pylori isolates with amino acid sequence polymorphisms as presence of both HtrA-L171 & CagL-Y58/E59 increase the risk of gastric cancer. J Biomed Sci. 2019 Jan 5;26(1):4. doi: 10.1186/s12929-019-0498-9
19. Hussein NR. The association of dupA and Helicobacter pylori-related gastroduodenal diseases. Eur J Clin Microbiol Infect Dis. 2010;29(7):817-21. doi: 10.1007/s10096-010-0933-z
20. Shiota S, Matsunari O, Watada M, Hanada K, Yamaoka Y. Systematic review and meta-analysis: the relationship between the Helicobacter pylori dupA gene and clinical outcomes. Gut Pathog. 2010;2(1):13. doi: 10.1186/1757-4749-2-13
21. Jung SW, Sugimoto M, Shiota S, Graham DY, Yamaoka Y. The intact dupA cluster is a more reliable Helicobacter pylori virulence marker than dupA alone. Infect Immun. 2012;80(1):381-7. doi: 10.1128/IAI.05472-11
22. Fujimoto S, Olaniyi OO, Arnqvist A, Wu JY, Odenbreit S, Haas R, et al. Helicobacter pylori BabA expression, gastric mucosal injury, and clinical outcome. Clin Gastroenterol Hepatol. 2007;5(1):49-58. doi: 10.1016/j.cgh.2006.09.015
23. Gerhard M, Lehn N, Neumayer N, Borén T, Rad R, Schepp W, et al. Clinical relevance of the Helicobacter pylori gene for blood-group antigen-binding adhesin. Proc Natl Acad Sci U S A. 1999;96(22):12778-83. doi: 10.1073/pnas.96.22.12778
24. Chen MY, He CY, Meng X, Yuan Y. Association of Helicobacter pylori babA2 with peptic ulcer disease and gastric cancer. World J Gastroenterol. 2013;19(26):4242-51. doi: 10.3748/wjg.v19.i26.4242
25. Su YL, Huang HL, Huang BS, Chen PC, Chen CS, Wang HL, et al. Combination of OipA, BabA, and SabA as candidate biomarkers for predicting Helicobacter pylori-related gastric cancer. Sci Rep. 2016 Nov 7;6:36442. doi: 10.1038/srep36442
26. Peek RM Jr, Thompson SA, Donahue JP, Tham KT, Atherton JC, Blaser MJ, Miller GG. Adherence to gastric epithelial cells induces expression of a Helicobacter pylori gene, iceA, that is associated with clinical outcome. Proc Assoc Am Physicians. 1998;110(6):531-44.
27. Shiota S, Watada M, Matsunari O, Iwatani S, Suzuki R, Yamaoka Y. Helicobacter pylori iceA, clinical outcomes, and correlation with cagA: a meta-analysis. PLoS One. 2012;7(1):e30354. doi: 10.1371/journal.pone.0030354
28. Dossumbekova A, Prinz C, Mages J, Lang R, Kusters JG, Vliet AH, et al. Helicobacter pylori HopH (OipA) and bacterial pathogenicity: genetic and functional genomic analysis of hopH gene polymorphisms. J Infect Dis. 2006;194(10):1346-55. doi: 10.1086/508426
29. Liu J, He C, Chen M, Wang Z, Xing C, Yuan Y. Association of presence/absence and on/off patterns of Helicobacter pylori oipA gene with peptic ulcer disease and gastric cancer risks: a meta-analysis. BMC Infect Dis. 2013;13:555. doi: 10.1186/1471-2334-13-555
30. Pakbaz Z, Shirazi MH, Ranjbar R, Reza M, Gholi MK, Aliramezani A, Malekshahi ZV. Frequency of sabA gene in Helicobacter pylori strains isolated from patients in Tehran, Iran. Iran Red Crescent Med J. 2013 Sep;15(9):767-70.
31. Goudarzi H, Rezaee H, Rafizadeh M, Taghav A. Determination of the status of Helicobacter pylori sabA gene in relation to clinical findings. J Med Bacteriol. 2012;1(1, 2):3-8.
32. Ma K, Baloch Z, He T-T, Xia X. Alcohol consumption and gastric cancer risk: A meta-analysis. Med Sci Monit. 2017;23:238-46.
33. Júnior UR, Viscondi JKY, Zilberstein B, Cecconello I, Eluf-Neto J. Risk factors associated with the development of gastric cancer – case-control study. Rev Assoc Med Bras. 2018;64(7):611-9. doi: 10.1590/1806-9282.64.07.611
34. Choi YJ, Myung SK, Lee JH. Light alcohol drinking and risk of cancer: A meta-analysis of cohort studies. Cancer Res Treat. 2018 Apr;50(2):474-87. doi: 10.4143/crt.2017.094
35. Rosenstock S, Jørgensen T, Bonnevie O, Andersen L. Risk factors for peptic ulcer disease: a population based prospective cohort study comprising 2416 Danish adults. Gut. 2003 Feb;52(2):186-93. doi: 10.1136/gut.52.2.186
36. Lin P-Y, Wang J-Yi, Shih D-P., Kuo H-W, Liang W-M. The Interaction Effects of Burnout and Job Support on Peptic Ulcer Disease among Firefighters and Policemen. Int J Environ Res Pub Health. 2019;16(13). pii: E2369. doi: 10.3390/ijerph16132369
37. Abioye AI, Odesanya MO, Abioye AI, Ibrahim NA. Physical activity and risk of gastric cancer: a meta-analysis of observational studies. Br J Sports Med. 2015 Feb;49(4):224-9. doi: 10.1136/bjsports-2013-092778
38. Ordóñez-Mena JM, Schöttker B, Mons U, Jenab M, Freisling H, et al. Quantification of the smoking-associated cancer risk with rate advancement periods: meta-analysis of individual participant data from cohorts of the CHANCES consortium. BMC Med. 2016;14:62. doi: 10.1186/s12916-016-0607-5
39. Yusefi AR, Bagheri Lankarani K, Bastani P, Radinmanesh M, Kavosi Z. Risk Factors for gastric cancer: A systematic review. Asian Pac J Cancer Prev. 2018 Mar 27;19(3):591-603.
40. Campbell PT, Sloan M, Kreiger N. dietary patterns and risk of incident gastric adenocarcinoma. Am J Epidemiol. 2008;167:295-304. doi: 10.1093/aje/kwm294
41. Kim J, Kim KH, Lee BJ. Association of peptic ulcer disease with obesity, nutritional components, and blood parameters in the Korean population. PLoS One. 2017;12(8):e0183777. doi: 10.1371/journal.pone.0183777
42. Edgren G, Hjalgrim H, Rostgaard K, Norda R, Wikman A, Melbye M, Nyrén O. Risk of gastric cancer and peptic ulcers in relation to AB0 blood type: a cohort study. Am J Epidemiol. 2010 Dec 1;172(11):1280-5. doi: 10.1093/aje/kwq299
43. Alkebsi L, Ideno Y, Lee J-S, Suzuki S, Nakajima-Shimada J, Ohnishi H, et al. Gastroduodenal Ulcers and ABO Blood Group: the Japan Nurses’ Health Study (JNHS). J Epidemiol. 2018;28(1):34-40. doi: 10.2188/jea.JE20160204
44. Balakrishnan M, George R, Sharma A, Graham DY. Changing trends in stomach cancer throughout the world. Curr Gastroenterol Rep. 2017;19(8):36. doi: 10.1007/s11894-017-0575-8
45. Sugimoto M, Furuta T, Shirai N, Nakamura A, Xiao F, Kajimura M, et al. Different effects of polymorphisms of tumor necrosis factor-alpha and interleukin-1 beta on development of peptic ulcer and gastric cancer. J Gastroenterol Hepatol. 2007 Jan;22(1):51-9.
46. Zhang J, Dou C, Song Y, Ji C, Gu S, Xie Y, Mao Y. Polymorphisms of tumor necrosis factor-alpha are associated with increased susceptibility to gastric cancer: a meta-analysis. J Hum Genet. 2008;53(6):479-89. doi: 10.1007/s10038-008-0273-3
47. Shibata T, Tahara T, Hirata I, Arisawa T. Genetic polymorphism of interleukin-17A and -17F genes in gastric carcinogenesis. Hum Immunol. 2009 Jul;70(7):547-51. doi: 10.1016/j.humimm.2009.04.030
48. Chakravorty M, Ghosh A, Choudhury A, Santra A, Hembrum J, Roychoudhury S. Interaction between IL1B gene promoter polymorphisms in determining susceptibility to Helicobacter pylori associated duodenal ulcer. Hum Mutat. 2006 May;27(5):411-9.
49. Hold GL, Rabkin CS, Chow WH, Smith MG, Gammon MD, Risch HA, et al. A functional polymorphism of toll-like receptor 4 gene increases risk of gastric carcinoma and its precursors. Gastroenterology. 2007 Mar;132(3):905-12.
50. Kang JM, Kim N, Lee DH, Park JH, Lee MK, Kim JS, et al. The effects of genetic polymorphisms of IL-6, IL-8, and IL-10 on Helicobacter pylori-induced gastroduodenal diseases in Korea. J Clin Gastroenterol. 2009 May-Jun;43(5):420-8. doi: 10.1097/MCG.0b013e318178d1d3
51. Musumba CO, Jorgensen A, Sutton L, Van Eker D, Zhang E, O'Hara N, et al. CYP2C19*17 gain-of-function polymorphism is associated with peptic ulcer disease. Clin Pharmacol Ther. 2013 Feb;93(2):195-203. doi: 10.1038/clpt.2012.215
52. Sugimoto M, Furuta T, Shirai N, Nakamura A, Kajimura M, Sugimura H, et al. Poor metabolizer genotype status of CYP2C19 is a risk factor for developing gastric cancer in Japanese patient s with Helicobacter pylori infection. Aliment Pharmacol Ther. 2005 Nov 15;22(10):1033-40.
53. Tanikawa C, Matsuo K, Kubo M, Takahashi A, Ito H, Tanaka H, et al. Impact of PSCA variation on gastric ulcer susceptibility. PloS One. 2013;8(5):e63698.
54. Kobayashi D, Takahashi O, Arioka H, Tsuguya Fukui T. The optimal screening interval for gastric cancer using esophago-gastro-duodenoscopy in Japan. BMC Gastroenterol. 2012;12:144. doi: 10.1186/1471-230X-12-144
55. Levenstein S, Rosenstock S, Jacobsen RK, Jorgensen T. Psychological stress increases risk for peptic ulcer, regardless of helicobacter pylori infection or use of nonsteroidal anti-inflammatory drugs. Clin Gastroenterol Hepatol. 2015;13:498-506.
56. Suh M, Wikoff D, Lipworth L, Goodman M, Fitch S, Mittal L, et al. Hexavalent chromium and stomach cancer: a systematic review and meta-analysis Crit Rev Toxicol. 2019 Mar;21:1-20. doi: 10.1080/10408444.2019.1578730
57. Sjödahl K, Jansson C, Bergdahl IA, Adami J, Boffetta P, Lagergren J. Airborne exposures and risk of gastric cancer: a prospective cohort study. Int J Cancer. 2007 May 1;120(9):2013-8.
58. Parent M-É, Siemiatycki J, Fritschi L. Occupational exposures and gastric cancer. Epidemiology. 1998;9:48-55.
59. Koh DH, Kim TW, Jang S, Ryu HW. Dust exposure and the risk of cancer in cement industry workers in Korea. Am J Industr Med. 2013;56(3):276-81. doi: 10.1002/ajim.22132
60. Lee W, Ahn YS, Lee S, Song BM, Hong S, Yoon JH. Occupational exposure to crystalline silica and gastric cancer: a systematic review and meta-analysis. Occup Environ Med. 2016 Nov;73(11):794-801. doi: 10.1136/oemed-2016-103552. Epub 2016 Sep 12.
61. Chang CJ, Tu YK, Chen PC, Yang HY. Talc exposure and risk of stomach cancer: Systematic review and meta-analysis of occupational cohort studies. J Formos Med Assoc. 2018 Aug 9. pii: S0929-6646(18)30353-X. doi: 10.1016/j.jfma.2018.07.015
62. Ye W, Chow WH, Lagergren J, Yin L, Nyrén O. Risk of adenocarcinomas of the esophagus and gastric cardia in patients with gastroesophageal reflux diseases and after antireflux surgery. Gastroenterology. 2001 Dec;121(6):1286-93.
63. Lin XJ, Wang CP, Liu XD, Yan KK, Li S, Bao HH, et al. Body mass index and risk of gastric cancer: a meta-analysis. Jpn J Clin Oncol. 2014 Sep;44(9):783-91. doi: 10.1093/jjco/hyu082
64. Kuipers EJ. Pernicious anemia, atrophic gastritis, and the risk of cancer. Clin Gastroenterol Hepatol. 2015;13:2290-2 doi: 10.1016/j.cgh.2015.07.013
65. Morton LM, Dores GM, Curtis RE, Lynch CF, Stovall M, Hall P, et al. Stomach cancer risk after treatment for hodgkin lymphoma. J Clin Oncol. 2013 Sep 20;31(27):3369-77. doi: 10.1200/JCO.2013.50.6832
66. Ohyauchi M, Imatani A, Yonechi M, Asano N, Miura A, Iijima K., Koike T, et al. The polymorphism interleukin 8 −251 A/T influences the susceptibility of Helicobacter pylori related gastric diseases in the Japanese population. Gut. 2005;54(3):330-5.
67. Yin YW, Hu AM, Sun QQ, Zhang BB, Wang Q, Liu HL, et al. Association between interleukin-8 gene −251 T/A polymorphism and the risk of peptic ulcer disease: a meta-analysis. Hum Immunol. 2013;74(1):125-30.
68. Ramis IB, Vianna JS, Gonçalves CV, von Groll A, Dellagostin OA, da Silva PEA. Polymorphisms of the IL-6, IL-8 and IL-10 genes and the risk of gastric pathology in patients infected with Helicobacter pylori. J Microbiol Immunol Infect. 2017 Apr;50(2):153-9. doi: 10.1016/j.jmii.2015.03.002
2. Маев И.В., Андреев Д.Н. Молекулярно-генетические предикторы резистентности к антихеликобактерной терапии. Терапевтический архив. 2017;89(8):5-12 [Maev IV, Andreev DN. Molecular genetic predictors of resistance to anti-Helicobacter pylori therapy. Therapeutic Archive. 2017;89(8):5-12 (In Russ.)]. doi: 10.17116/terarkh20178985-12
3. Андреев Д.Н., Дичева Д.Т., Маев И.В. Возможности оптимизации эрадикационной терапии инфекции Helicobacter pylori в современной клинической практике. Терапевтический архив. 2017;89(2):84-90 [Andreev DN, Dicheva DT, Maev IV. Possibilities for optimization of eradication therapy for Helicobacter pylori infection in modern clinical practice. Therapeutic Archive. 2017;89(2):84-90 (In Russ.)]. doi: 10.17116/terarkh201789284-90
4. Chang WL, Yeh YC, Sheu BS. The impacts of H. pylori virulence factors on the development of gastroduodenal diseases. J Biomed Sci. 2018 Sep 11;25(1):68. doi: 10.1186/s12929-018-0466-9
5. Kwok T, Zabler D, Urman S, Rohde M, Hartig R, Wessler S, et al. Helicobacter exploits integrin for type IV secretion and kinase activation. Nature. 2007;449(7164):862-6. doi: 10.1038/nature06187
6. Hayashi Y, Tsujii M, Wang J, Kondo J, Akasaka T, Jin Y, et al. CagA mediates epigenetic regulation to attenuate let-7 expression in Helicobacter pylori-related carcinogenesis. Gut. 2013;62(11):1536-46. doi: 10.1136/gutjnl-2011-301625
7. Huang JQ, Zheng GF, Sumanac K, Irvine EJ, Hunt RH. Meta-analysis of the relationship between cagA seropositivity and gastric cancer. Gastroenterology. 2003 Dec;125(6):1636-44.
8. Yeh YC, Chang WL, Yang HB, Cheng HC, Wu JJ, Sheu BS. H. pylori cagL amino acid sequence polymorphism Y58E59 induces a corpus shift of gastric integrin α5β1 related with gastric carcinogenesis. Mol Carcinog. 2011 Oct;50(10):751-9. doi: 10.1002/mc.20753
9. Li Q, Liu J, Gong Y, Yuan Y. Association of CagA EPIYA-D or EPIYA-C phosphorylation sites with peptic ulcer and gastric cancer risks: a meta-analysis. Medicine (Baltimore). 2017;96(17):e6620. doi: 10.1097/MD.0000000000006620
10. Zhang X-S, Tegtmeyer N, Traube L, Jindal S, Perez-Perez G, Backert S, Blaser MJ. A specific A/T polymorphism in western tyrosine phosphorylation b-motifs regulates helicobacter pylori caga epithelial cell interactions. PLoS Pathog. 2015 Feb;11(2):e1004621. doi: 10.1371/journal.ppat.1004621
11. Delchier JC, Lamarque D, Levy M, Tkoub EM, Copie-Bergman C, Deforges L, et al. Helicobacter pylori and gastric lymphoma: high seroprevalence of CagA in diffuse large B-cell lymphoma but not in low-grade lymphoma of mucosa-associated lymphoid tissue type. Am J Gastroenterol. 2001;96(8):2324-8. doi: 10.1111/j.1572-0241.2001.04036.x
12. Kuo SH, Yeh KH, Chen LT, Lin CW, Hsu PN, Wu MS, et al. Helicobacter pylori CagA translocation is closely associated with the expression of CagA-signaling molecules in low-grade gastric mucosa-associated lymphoid tissue lymphoma. Am J Surg Pathol. 2015;39(6):761-6. doi: 10.1097/PAS.0000000000000437
13. Matos JI, de Sousa HA, Marcos-Pinto R, Dinis-Ribeiro M. Helicobacter pylori CagA and VacA genotypes and gastric phenotype: a meta-analysis. Eur J Gastroenterol Hepatol. 2013 Dec;25(12):1431-41. doi: 10.1097/MEG.0b013e328364b53e
14. Liu X, He B, Cho WC, Pan Y, Chen J, Ying H, et al. A systematic review on the association between the Helicobacter pylori vacA I genotype and gastric disease. FEBS Open Bio. 2016;6(5):409-17. doi: 10.1002/2211-5463.12046
15. Gonzalez CA, Figueiredo C, Lic CB, Ferreira RM, Pardo ML, Ruiz Liso JM, et al. Helicobacter pylori cagA and vacA genotypes as predictors of progression of gastric preneoplastic lesions: a long-term follow-up in a high-risk area in Spain. Am J Gastroenterol. 2011;106(5):867-74. doi: 10.1038/ajg.2011.1
16. Sugimoto M, Yamaoka Y. The association of vacA genotype and Helicobacter pylori-related disease in Latin American and African populations. Clin Microbiol Infect. 2009;15(9):835-42. doi: 10.1111/j.1469-0691.2009.02769.x
17. Sahara S, Sugimoto M, Vilaichone RK, Mahachai V, Miyajima H, Furuta T, et al. Role of Helicobacter pylori cagA EPIYA motif and vacA genotypes for the development of gastrointestinal diseases in Southeast Asian countries: a meta-analysis. BMC Infect Dis. 2012;12:223. doi: 10.1186/1471-2334-12-223
18. Yeh YC, Kuo HY, Chang WL,Yang HB, Lu CC, Cheng HC, et al. H. pylori isolates with amino acid sequence polymorphisms as presence of both HtrA-L171 & CagL-Y58/E59 increase the risk of gastric cancer. J Biomed Sci. 2019 Jan 5;26(1):4. doi: 10.1186/s12929-019-0498-9
19. Hussein NR. The association of dupA and Helicobacter pylori-related gastroduodenal diseases. Eur J Clin Microbiol Infect Dis. 2010;29(7):817-21. doi: 10.1007/s10096-010-0933-z
20. Shiota S, Matsunari O, Watada M, Hanada K, Yamaoka Y. Systematic review and meta-analysis: the relationship between the Helicobacter pylori dupA gene and clinical outcomes. Gut Pathog. 2010;2(1):13. doi: 10.1186/1757-4749-2-13
21. Jung SW, Sugimoto M, Shiota S, Graham DY, Yamaoka Y. The intact dupA cluster is a more reliable Helicobacter pylori virulence marker than dupA alone. Infect Immun. 2012;80(1):381-7. doi: 10.1128/IAI.05472-11
22. Fujimoto S, Olaniyi OO, Arnqvist A, Wu JY, Odenbreit S, Haas R, et al. Helicobacter pylori BabA expression, gastric mucosal injury, and clinical outcome. Clin Gastroenterol Hepatol. 2007;5(1):49-58. doi: 10.1016/j.cgh.2006.09.015
23. Gerhard M, Lehn N, Neumayer N, Borén T, Rad R, Schepp W, et al. Clinical relevance of the Helicobacter pylori gene for blood-group antigen-binding adhesin. Proc Natl Acad Sci U S A. 1999;96(22):12778-83. doi: 10.1073/pnas.96.22.12778
24. Chen MY, He CY, Meng X, Yuan Y. Association of Helicobacter pylori babA2 with peptic ulcer disease and gastric cancer. World J Gastroenterol. 2013;19(26):4242-51. doi: 10.3748/wjg.v19.i26.4242
25. Su YL, Huang HL, Huang BS, Chen PC, Chen CS, Wang HL, et al. Combination of OipA, BabA, and SabA as candidate biomarkers for predicting Helicobacter pylori-related gastric cancer. Sci Rep. 2016 Nov 7;6:36442. doi: 10.1038/srep36442
26. Peek RM Jr, Thompson SA, Donahue JP, Tham KT, Atherton JC, Blaser MJ, Miller GG. Adherence to gastric epithelial cells induces expression of a Helicobacter pylori gene, iceA, that is associated with clinical outcome. Proc Assoc Am Physicians. 1998;110(6):531-44.
27. Shiota S, Watada M, Matsunari O, Iwatani S, Suzuki R, Yamaoka Y. Helicobacter pylori iceA, clinical outcomes, and correlation with cagA: a meta-analysis. PLoS One. 2012;7(1):e30354. doi: 10.1371/journal.pone.0030354
28. Dossumbekova A, Prinz C, Mages J, Lang R, Kusters JG, Vliet AH, et al. Helicobacter pylori HopH (OipA) and bacterial pathogenicity: genetic and functional genomic analysis of hopH gene polymorphisms. J Infect Dis. 2006;194(10):1346-55. doi: 10.1086/508426
29. Liu J, He C, Chen M, Wang Z, Xing C, Yuan Y. Association of presence/absence and on/off patterns of Helicobacter pylori oipA gene with peptic ulcer disease and gastric cancer risks: a meta-analysis. BMC Infect Dis. 2013;13:555. doi: 10.1186/1471-2334-13-555
30. Pakbaz Z, Shirazi MH, Ranjbar R, Reza M, Gholi MK, Aliramezani A, Malekshahi ZV. Frequency of sabA gene in Helicobacter pylori strains isolated from patients in Tehran, Iran. Iran Red Crescent Med J. 2013 Sep;15(9):767-70.
31. Goudarzi H, Rezaee H, Rafizadeh M, Taghav A. Determination of the status of Helicobacter pylori sabA gene in relation to clinical findings. J Med Bacteriol. 2012;1(1, 2):3-8.
32. Ma K, Baloch Z, He T-T, Xia X. Alcohol consumption and gastric cancer risk: A meta-analysis. Med Sci Monit. 2017;23:238-46.
33. Júnior UR, Viscondi JKY, Zilberstein B, Cecconello I, Eluf-Neto J. Risk factors associated with the development of gastric cancer – case-control study. Rev Assoc Med Bras. 2018;64(7):611-9. doi: 10.1590/1806-9282.64.07.611
34. Choi YJ, Myung SK, Lee JH. Light alcohol drinking and risk of cancer: A meta-analysis of cohort studies. Cancer Res Treat. 2018 Apr;50(2):474-87. doi: 10.4143/crt.2017.094
35. Rosenstock S, Jørgensen T, Bonnevie O, Andersen L. Risk factors for peptic ulcer disease: a population based prospective cohort study comprising 2416 Danish adults. Gut. 2003 Feb;52(2):186-93. doi: 10.1136/gut.52.2.186
36. Lin P-Y, Wang J-Yi, Shih D-P., Kuo H-W, Liang W-M. The Interaction Effects of Burnout and Job Support on Peptic Ulcer Disease among Firefighters and Policemen. Int J Environ Res Pub Health. 2019;16(13). pii: E2369. doi: 10.3390/ijerph16132369
37. Abioye AI, Odesanya MO, Abioye AI, Ibrahim NA. Physical activity and risk of gastric cancer: a meta-analysis of observational studies. Br J Sports Med. 2015 Feb;49(4):224-9. doi: 10.1136/bjsports-2013-092778
38. Ordóñez-Mena JM, Schöttker B, Mons U, Jenab M, Freisling H, et al. Quantification of the smoking-associated cancer risk with rate advancement periods: meta-analysis of individual participant data from cohorts of the CHANCES consortium. BMC Med. 2016;14:62. doi: 10.1186/s12916-016-0607-5
39. Yusefi AR, Bagheri Lankarani K, Bastani P, Radinmanesh M, Kavosi Z. Risk Factors for gastric cancer: A systematic review. Asian Pac J Cancer Prev. 2018 Mar 27;19(3):591-603.
40. Campbell PT, Sloan M, Kreiger N. dietary patterns and risk of incident gastric adenocarcinoma. Am J Epidemiol. 2008;167:295-304. doi: 10.1093/aje/kwm294
41. Kim J, Kim KH, Lee BJ. Association of peptic ulcer disease with obesity, nutritional components, and blood parameters in the Korean population. PLoS One. 2017;12(8):e0183777. doi: 10.1371/journal.pone.0183777
42. Edgren G, Hjalgrim H, Rostgaard K, Norda R, Wikman A, Melbye M, Nyrén O. Risk of gastric cancer and peptic ulcers in relation to AB0 blood type: a cohort study. Am J Epidemiol. 2010 Dec 1;172(11):1280-5. doi: 10.1093/aje/kwq299
43. Alkebsi L, Ideno Y, Lee J-S, Suzuki S, Nakajima-Shimada J, Ohnishi H, et al. Gastroduodenal Ulcers and ABO Blood Group: the Japan Nurses’ Health Study (JNHS). J Epidemiol. 2018;28(1):34-40. doi: 10.2188/jea.JE20160204
44. Balakrishnan M, George R, Sharma A, Graham DY. Changing trends in stomach cancer throughout the world. Curr Gastroenterol Rep. 2017;19(8):36. doi: 10.1007/s11894-017-0575-8
45. Sugimoto M, Furuta T, Shirai N, Nakamura A, Xiao F, Kajimura M, et al. Different effects of polymorphisms of tumor necrosis factor-alpha and interleukin-1 beta on development of peptic ulcer and gastric cancer. J Gastroenterol Hepatol. 2007 Jan;22(1):51-9.
46. Zhang J, Dou C, Song Y, Ji C, Gu S, Xie Y, Mao Y. Polymorphisms of tumor necrosis factor-alpha are associated with increased susceptibility to gastric cancer: a meta-analysis. J Hum Genet. 2008;53(6):479-89. doi: 10.1007/s10038-008-0273-3
47. Shibata T, Tahara T, Hirata I, Arisawa T. Genetic polymorphism of interleukin-17A and -17F genes in gastric carcinogenesis. Hum Immunol. 2009 Jul;70(7):547-51. doi: 10.1016/j.humimm.2009.04.030
48. Chakravorty M, Ghosh A, Choudhury A, Santra A, Hembrum J, Roychoudhury S. Interaction between IL1B gene promoter polymorphisms in determining susceptibility to Helicobacter pylori associated duodenal ulcer. Hum Mutat. 2006 May;27(5):411-9.
49. Hold GL, Rabkin CS, Chow WH, Smith MG, Gammon MD, Risch HA, et al. A functional polymorphism of toll-like receptor 4 gene increases risk of gastric carcinoma and its precursors. Gastroenterology. 2007 Mar;132(3):905-12.
50. Kang JM, Kim N, Lee DH, Park JH, Lee MK, Kim JS, et al. The effects of genetic polymorphisms of IL-6, IL-8, and IL-10 on Helicobacter pylori-induced gastroduodenal diseases in Korea. J Clin Gastroenterol. 2009 May-Jun;43(5):420-8. doi: 10.1097/MCG.0b013e318178d1d3
51. Musumba CO, Jorgensen A, Sutton L, Van Eker D, Zhang E, O'Hara N, et al. CYP2C19*17 gain-of-function polymorphism is associated with peptic ulcer disease. Clin Pharmacol Ther. 2013 Feb;93(2):195-203. doi: 10.1038/clpt.2012.215
52. Sugimoto M, Furuta T, Shirai N, Nakamura A, Kajimura M, Sugimura H, et al. Poor metabolizer genotype status of CYP2C19 is a risk factor for developing gastric cancer in Japanese patient s with Helicobacter pylori infection. Aliment Pharmacol Ther. 2005 Nov 15;22(10):1033-40.
53. Tanikawa C, Matsuo K, Kubo M, Takahashi A, Ito H, Tanaka H, et al. Impact of PSCA variation on gastric ulcer susceptibility. PloS One. 2013;8(5):e63698.
54. Kobayashi D, Takahashi O, Arioka H, Tsuguya Fukui T. The optimal screening interval for gastric cancer using esophago-gastro-duodenoscopy in Japan. BMC Gastroenterol. 2012;12:144. doi: 10.1186/1471-230X-12-144
55. Levenstein S, Rosenstock S, Jacobsen RK, Jorgensen T. Psychological stress increases risk for peptic ulcer, regardless of helicobacter pylori infection or use of nonsteroidal anti-inflammatory drugs. Clin Gastroenterol Hepatol. 2015;13:498-506.
56. Suh M, Wikoff D, Lipworth L, Goodman M, Fitch S, Mittal L, et al. Hexavalent chromium and stomach cancer: a systematic review and meta-analysis Crit Rev Toxicol. 2019 Mar;21:1-20. doi: 10.1080/10408444.2019.1578730
57. Sjödahl K, Jansson C, Bergdahl IA, Adami J, Boffetta P, Lagergren J. Airborne exposures and risk of gastric cancer: a prospective cohort study. Int J Cancer. 2007 May 1;120(9):2013-8.
58. Parent M-É, Siemiatycki J, Fritschi L. Occupational exposures and gastric cancer. Epidemiology. 1998;9:48-55.
59. Koh DH, Kim TW, Jang S, Ryu HW. Dust exposure and the risk of cancer in cement industry workers in Korea. Am J Industr Med. 2013;56(3):276-81. doi: 10.1002/ajim.22132
60. Lee W, Ahn YS, Lee S, Song BM, Hong S, Yoon JH. Occupational exposure to crystalline silica and gastric cancer: a systematic review and meta-analysis. Occup Environ Med. 2016 Nov;73(11):794-801. doi: 10.1136/oemed-2016-103552. Epub 2016 Sep 12.
61. Chang CJ, Tu YK, Chen PC, Yang HY. Talc exposure and risk of stomach cancer: Systematic review and meta-analysis of occupational cohort studies. J Formos Med Assoc. 2018 Aug 9. pii: S0929-6646(18)30353-X. doi: 10.1016/j.jfma.2018.07.015
62. Ye W, Chow WH, Lagergren J, Yin L, Nyrén O. Risk of adenocarcinomas of the esophagus and gastric cardia in patients with gastroesophageal reflux diseases and after antireflux surgery. Gastroenterology. 2001 Dec;121(6):1286-93.
63. Lin XJ, Wang CP, Liu XD, Yan KK, Li S, Bao HH, et al. Body mass index and risk of gastric cancer: a meta-analysis. Jpn J Clin Oncol. 2014 Sep;44(9):783-91. doi: 10.1093/jjco/hyu082
64. Kuipers EJ. Pernicious anemia, atrophic gastritis, and the risk of cancer. Clin Gastroenterol Hepatol. 2015;13:2290-2 doi: 10.1016/j.cgh.2015.07.013
65. Morton LM, Dores GM, Curtis RE, Lynch CF, Stovall M, Hall P, et al. Stomach cancer risk after treatment for hodgkin lymphoma. J Clin Oncol. 2013 Sep 20;31(27):3369-77. doi: 10.1200/JCO.2013.50.6832
66. Ohyauchi M, Imatani A, Yonechi M, Asano N, Miura A, Iijima K., Koike T, et al. The polymorphism interleukin 8 −251 A/T influences the susceptibility of Helicobacter pylori related gastric diseases in the Japanese population. Gut. 2005;54(3):330-5.
67. Yin YW, Hu AM, Sun QQ, Zhang BB, Wang Q, Liu HL, et al. Association between interleukin-8 gene −251 T/A polymorphism and the risk of peptic ulcer disease: a meta-analysis. Hum Immunol. 2013;74(1):125-30.
68. Ramis IB, Vianna JS, Gonçalves CV, von Groll A, Dellagostin OA, da Silva PEA. Polymorphisms of the IL-6, IL-8 and IL-10 genes and the risk of gastric pathology in patients infected with Helicobacter pylori. J Microbiol Immunol Infect. 2017 Apr;50(2):153-9. doi: 10.1016/j.jmii.2015.03.002
________________________________________________
2. Maev IV, Andreev DN. Molecular genetic predictors of resistance to anti-Helicobacter pylori therapy. Therapeutic Archive. 2017;89(8):5-12 (In Russ.) doi: 10.17116/terarkh20178985-12
3. Andreev DN, Dicheva DT, Maev IV. Possibilities for optimization of eradication therapy for Helicobacter pylori infection in modern clinical practice. Therapeutic Archive. 2017;89(2):84-90 (In Russ.) doi: 10.17116/terarkh201789284-90
4. Chang WL, Yeh YC, Sheu BS. The impacts of H. pylori virulence factors on the development of gastroduodenal diseases. J Biomed Sci. 2018 Sep 11;25(1):68. doi: 10.1186/s12929-018-0466-9
5. Kwok T, Zabler D, Urman S, Rohde M, Hartig R, Wessler S, et al. Helicobacter exploits integrin for type IV secretion and kinase activation. Nature. 2007;449(7164):862-6. doi: 10.1038/nature06187
6. Hayashi Y, Tsujii M, Wang J, Kondo J, Akasaka T, Jin Y, et al. CagA mediates epigenetic regulation to attenuate let-7 expression in Helicobacter pylori-related carcinogenesis. Gut. 2013;62(11):1536-46. doi: 10.1136/gutjnl-2011-301625
7. Huang JQ, Zheng GF, Sumanac K, Irvine EJ, Hunt RH. Meta-analysis of the relationship between cagA seropositivity and gastric cancer. Gastroenterology. 2003 Dec;125(6):1636-44.
8. Yeh YC, Chang WL, Yang HB, Cheng HC, Wu JJ, Sheu BS. H. pylori cagL amino acid sequence polymorphism Y58E59 induces a corpus shift of gastric integrin α5β1 related with gastric carcinogenesis. Mol Carcinog. 2011 Oct;50(10):751-9. doi: 10.1002/mc.20753
9. Li Q, Liu J, Gong Y, Yuan Y. Association of CagA EPIYA-D or EPIYA-C phosphorylation sites with peptic ulcer and gastric cancer risks: a meta-analysis. Medicine (Baltimore). 2017;96(17):e6620. doi: 10.1097/MD.0000000000006620
10. Zhang X-S, Tegtmeyer N, Traube L, Jindal S, Perez-Perez G, Backert S, Blaser MJ. A specific A/T polymorphism in western tyrosine phosphorylation b-motifs regulates helicobacter pylori caga epithelial cell interactions. PLoS Pathog. 2015 Feb;11(2):e1004621. doi: 10.1371/journal.ppat.1004621
11. Delchier JC, Lamarque D, Levy M, Tkoub EM, Copie-Bergman C, Deforges L, et al. Helicobacter pylori and gastric lymphoma: high seroprevalence of CagA in diffuse large B-cell lymphoma but not in low-grade lymphoma of mucosa-associated lymphoid tissue type. Am J Gastroenterol. 2001;96(8):2324-8. doi: 10.1111/j.1572-0241.2001.04036.x
12. Kuo SH, Yeh KH, Chen LT, Lin CW, Hsu PN, Wu MS, et al. Helicobacter pylori CagA translocation is closely associated with the expression of CagA-signaling molecules in low-grade gastric mucosa-associated lymphoid tissue lymphoma. Am J Surg Pathol. 2015;39(6):761-6. doi: 10.1097/PAS.0000000000000437
13. Matos JI, de Sousa HA, Marcos-Pinto R, Dinis-Ribeiro M. Helicobacter pylori CagA and VacA genotypes and gastric phenotype: a meta-analysis. Eur J Gastroenterol Hepatol. 2013 Dec;25(12):1431-41. doi: 10.1097/MEG.0b013e328364b53e
14. Liu X, He B, Cho WC, Pan Y, Chen J, Ying H, et al. A systematic review on the association between the Helicobacter pylori vacA I genotype and gastric disease. FEBS Open Bio. 2016;6(5):409-17. doi: 10.1002/2211-5463.12046
15. Gonzalez CA, Figueiredo C, Lic CB, Ferreira RM, Pardo ML, Ruiz Liso JM, et al. Helicobacter pylori cagA and vacA genotypes as predictors of progression of gastric preneoplastic lesions: a long-term follow-up in a high-risk area in Spain. Am J Gastroenterol. 2011;106(5):867-74. doi: 10.1038/ajg.2011.1
16. Sugimoto M, Yamaoka Y. The association of vacA genotype and Helicobacter pylori-related disease in Latin American and African populations. Clin Microbiol Infect. 2009;15(9):835-42. doi: 10.1111/j.1469-0691.2009.02769.x
17. Sahara S, Sugimoto M, Vilaichone RK, Mahachai V, Miyajima H, Furuta T, et al. Role of Helicobacter pylori cagA EPIYA motif and vacA genotypes for the development of gastrointestinal diseases in Southeast Asian countries: a meta-analysis. BMC Infect Dis. 2012;12:223. doi: 10.1186/1471-2334-12-223
18. Yeh YC, Kuo HY, Chang WL,Yang HB, Lu CC, Cheng HC, et al. H. pylori isolates with amino acid sequence polymorphisms as presence of both HtrA-L171 & CagL-Y58/E59 increase the risk of gastric cancer. J Biomed Sci. 2019 Jan 5;26(1):4. doi: 10.1186/s12929-019-0498-9
19. Hussein NR. The association of dupA and Helicobacter pylori-related gastroduodenal diseases. Eur J Clin Microbiol Infect Dis. 2010;29(7):817-21. doi: 10.1007/s10096-010-0933-z
20. Shiota S, Matsunari O, Watada M, Hanada K, Yamaoka Y. Systematic review and meta-analysis: the relationship between the Helicobacter pylori dupA gene and clinical outcomes. Gut Pathog. 2010;2(1):13. doi: 10.1186/1757-4749-2-13
21. Jung SW, Sugimoto M, Shiota S, Graham DY, Yamaoka Y. The intact dupA cluster is a more reliable Helicobacter pylori virulence marker than dupA alone. Infect Immun. 2012;80(1):381-7. doi: 10.1128/IAI.05472-11
22. Fujimoto S, Olaniyi OO, Arnqvist A, Wu JY, Odenbreit S, Haas R, et al. Helicobacter pylori BabA expression, gastric mucosal injury, and clinical outcome. Clin Gastroenterol Hepatol. 2007;5(1):49-58. doi: 10.1016/j.cgh.2006.09.015
23. Gerhard M, Lehn N, Neumayer N, Borén T, Rad R, Schepp W, et al. Clinical relevance of the Helicobacter pylori gene for blood-group antigen-binding adhesin. Proc Natl Acad Sci U S A. 1999;96(22):12778-83. doi: 10.1073/pnas.96.22.12778
24. Chen MY, He CY, Meng X, Yuan Y. Association of Helicobacter pylori babA2 with peptic ulcer disease and gastric cancer. World J Gastroenterol. 2013;19(26):4242-51. doi: 10.3748/wjg.v19.i26.4242
25. Su YL, Huang HL, Huang BS, Chen PC, Chen CS, Wang HL, et al. Combination of OipA, BabA, and SabA as candidate biomarkers for predicting Helicobacter pylori-related gastric cancer. Sci Rep. 2016 Nov 7;6:36442. doi: 10.1038/srep36442
26. Peek RM Jr, Thompson SA, Donahue JP, Tham KT, Atherton JC, Blaser MJ, Miller GG. Adherence to gastric epithelial cells induces expression of a Helicobacter pylori gene, iceA, that is associated with clinical outcome. Proc Assoc Am Physicians. 1998;110(6):531-44.
27. Shiota S, Watada M, Matsunari O, Iwatani S, Suzuki R, Yamaoka Y. Helicobacter pylori iceA, clinical outcomes, and correlation with cagA: a meta-analysis. PLoS One. 2012;7(1):e30354. doi: 10.1371/journal.pone.0030354
28. Dossumbekova A, Prinz C, Mages J, Lang R, Kusters JG, Vliet AH, et al. Helicobacter pylori HopH (OipA) and bacterial pathogenicity: genetic and functional genomic analysis of hopH gene polymorphisms. J Infect Dis. 2006;194(10):1346-55. doi: 10.1086/508426
29. Liu J, He C, Chen M, Wang Z, Xing C, Yuan Y. Association of presence/absence and on/off patterns of Helicobacter pylori oipA gene with peptic ulcer disease and gastric cancer risks: a meta-analysis. BMC Infect Dis. 2013;13:555. doi: 10.1186/1471-2334-13-555
30. Pakbaz Z, Shirazi MH, Ranjbar R, Reza M, Gholi MK, Aliramezani A, Malekshahi ZV. Frequency of sabA gene in Helicobacter pylori strains isolated from patients in Tehran, Iran. Iran Red Crescent Med J. 2013 Sep;15(9):767-70.
31. Goudarzi H, Rezaee H, Rafizadeh M, Taghav A. Determination of the status of Helicobacter pylori sabA gene in relation to clinical findings. J Med Bacteriol. 2012;1(1, 2):3-8.
32. Ma K, Baloch Z, He T-T, Xia X. Alcohol consumption and gastric cancer risk: A meta-analysis. Med Sci Monit. 2017;23:238-46.
33. Júnior UR, Viscondi JKY, Zilberstein B, Cecconello I, Eluf-Neto J. Risk factors associated with the development of gastric cancer – case-control study. Rev Assoc Med Bras. 2018;64(7):611-9. doi: 10.1590/1806-9282.64.07.611
34. Choi YJ, Myung SK, Lee JH. Light alcohol drinking and risk of cancer: A meta-analysis of cohort studies. Cancer Res Treat. 2018 Apr;50(2):474-87. doi: 10.4143/crt.2017.094
35. Rosenstock S, Jørgensen T, Bonnevie O, Andersen L. Risk factors for peptic ulcer disease: a population based prospective cohort study comprising 2416 Danish adults. Gut. 2003 Feb;52(2):186-93. doi: 10.1136/gut.52.2.186
36. Lin P-Y, Wang J-Yi, Shih D-P., Kuo H-W, Liang W-M. The Interaction Effects of Burnout and Job Support on Peptic Ulcer Disease among Firefighters and Policemen. Int J Environ Res Pub Health. 2019;16(13). pii: E2369. doi: 10.3390/ijerph16132369
37. Abioye AI, Odesanya MO, Abioye AI, Ibrahim NA. Physical activity and risk of gastric cancer: a meta-analysis of observational studies. Br J Sports Med. 2015 Feb;49(4):224-9. doi: 10.1136/bjsports-2013-092778
38. Ordóñez-Mena JM, Schöttker B, Mons U, Jenab M, Freisling H, et al. Quantification of the smoking-associated cancer risk with rate advancement periods: meta-analysis of individual participant data from cohorts of the CHANCES consortium. BMC Med. 2016;14:62. doi: 10.1186/s12916-016-0607-5
39. Yusefi AR, Bagheri Lankarani K, Bastani P, Radinmanesh M, Kavosi Z. Risk Factors for gastric cancer: A systematic review. Asian Pac J Cancer Prev. 2018 Mar 27;19(3):591-603.
40. Campbell PT, Sloan M, Kreiger N. dietary patterns and risk of incident gastric adenocarcinoma. Am J Epidemiol. 2008;167:295-304. doi: 10.1093/aje/kwm294
41. Kim J, Kim KH, Lee BJ. Association of peptic ulcer disease with obesity, nutritional components, and blood parameters in the Korean population. PLoS One. 2017;12(8):e0183777. doi: 10.1371/journal.pone.0183777
42. Edgren G, Hjalgrim H, Rostgaard K, Norda R, Wikman A, Melbye M, Nyrén O. Risk of gastric cancer and peptic ulcers in relation to AB0 blood type: a cohort study. Am J Epidemiol. 2010 Dec 1;172(11):1280-5. doi: 10.1093/aje/kwq299
43. Alkebsi L, Ideno Y, Lee J-S, Suzuki S, Nakajima-Shimada J, Ohnishi H, et al. Gastroduodenal Ulcers and ABO Blood Group: the Japan Nurses’ Health Study (JNHS). J Epidemiol. 2018;28(1):34-40. doi: 10.2188/jea.JE20160204
44. Balakrishnan M, George R, Sharma A, Graham DY. Changing trends in stomach cancer throughout the world. Curr Gastroenterol Rep. 2017;19(8):36. doi: 10.1007/s11894-017-0575-8
45. Sugimoto M, Furuta T, Shirai N, Nakamura A, Xiao F, Kajimura M, et al. Different effects of polymorphisms of tumor necrosis factor-alpha and interleukin-1 beta on development of peptic ulcer and gastric cancer. J Gastroenterol Hepatol. 2007 Jan;22(1):51-9.
46. Zhang J, Dou C, Song Y, Ji C, Gu S, Xie Y, Mao Y. Polymorphisms of tumor necrosis factor-alpha are associated with increased susceptibility to gastric cancer: a meta-analysis. J Hum Genet. 2008;53(6):479-89. doi: 10.1007/s10038-008-0273-3
47. Shibata T, Tahara T, Hirata I, Arisawa T. Genetic polymorphism of interleukin-17A and -17F genes in gastric carcinogenesis. Hum Immunol. 2009 Jul;70(7):547-51. doi: 10.1016/j.humimm.2009.04.030
48. Chakravorty M, Ghosh A, Choudhury A, Santra A, Hembrum J, Roychoudhury S. Interaction between IL1B gene promoter polymorphisms in determining susceptibility to Helicobacter pylori associated duodenal ulcer. Hum Mutat. 2006 May;27(5):411-9.
49. Hold GL, Rabkin CS, Chow WH, Smith MG, Gammon MD, Risch HA, et al. A functional polymorphism of toll-like receptor 4 gene increases risk of gastric carcinoma and its precursors. Gastroenterology. 2007 Mar;132(3):905-12.
50. Kang JM, Kim N, Lee DH, Park JH, Lee MK, Kim JS, et al. The effects of genetic polymorphisms of IL-6, IL-8, and IL-10 on Helicobacter pylori-induced gastroduodenal diseases in Korea. J Clin Gastroenterol. 2009 May-Jun;43(5):420-8. doi: 10.1097/MCG.0b013e318178d1d3
51. Musumba CO, Jorgensen A, Sutton L, Van Eker D, Zhang E, O'Hara N, et al. CYP2C19*17 gain-of-function polymorphism is associated with peptic ulcer disease. Clin Pharmacol Ther. 2013 Feb;93(2):195-203. doi: 10.1038/clpt.2012.215
52. Sugimoto M, Furuta T, Shirai N, Nakamura A, Kajimura M, Sugimura H, et al. Poor metabolizer genotype status of CYP2C19 is a risk factor for developing gastric cancer in Japanese patient s with Helicobacter pylori infection. Aliment Pharmacol Ther. 2005 Nov 15;22(10):1033-40.
53. Tanikawa C, Matsuo K, Kubo M, Takahashi A, Ito H, Tanaka H, et al. Impact of PSCA variation on gastric ulcer susceptibility. PloS One. 2013;8(5):e63698.
54. Kobayashi D, Takahashi O, Arioka H, Tsuguya Fukui T. The optimal screening interval for gastric cancer using esophago-gastro-duodenoscopy in Japan. BMC Gastroenterol. 2012;12:144. doi: 10.1186/1471-230X-12-144
55. Levenstein S, Rosenstock S, Jacobsen RK, Jorgensen T. Psychological stress increases risk for peptic ulcer, regardless of helicobacter pylori infection or use of nonsteroidal anti-inflammatory drugs. Clin Gastroenterol Hepatol. 2015;13:498-506.
56. Suh M, Wikoff D, Lipworth L, Goodman M, Fitch S, Mittal L, et al. Hexavalent chromium and stomach cancer: a systematic review and meta-analysis Crit Rev Toxicol. 2019 Mar;21:1-20. doi: 10.1080/10408444.2019.1578730
57. Sjödahl K, Jansson C, Bergdahl IA, Adami J, Boffetta P, Lagergren J. Airborne exposures and risk of gastric cancer: a prospective cohort study. Int J Cancer. 2007 May 1;120(9):2013-8.
58. Parent M-É, Siemiatycki J, Fritschi L. Occupational exposures and gastric cancer. Epidemiology. 1998;9:48-55.
59. Koh DH, Kim TW, Jang S, Ryu HW. Dust exposure and the risk of cancer in cement industry workers in Korea. Am J Industr Med. 2013;56(3):276-81. doi: 10.1002/ajim.22132
60. Lee W, Ahn YS, Lee S, Song BM, Hong S, Yoon JH. Occupational exposure to crystalline silica and gastric cancer: a systematic review and meta-analysis. Occup Environ Med. 2016 Nov;73(11):794-801. doi: 10.1136/oemed-2016-103552. Epub 2016 Sep 12.
61. Chang CJ, Tu YK, Chen PC, Yang HY. Talc exposure and risk of stomach cancer: Systematic review and meta-analysis of occupational cohort studies. J Formos Med Assoc. 2018 Aug 9. pii: S0929-6646(18)30353-X. doi: 10.1016/j.jfma.2018.07.015
62. Ye W, Chow WH, Lagergren J, Yin L, Nyrén O. Risk of adenocarcinomas of the esophagus and gastric cardia in patients with gastroesophageal reflux diseases and after antireflux surgery. Gastroenterology. 2001 Dec;121(6):1286-93.
63. Lin XJ, Wang CP, Liu XD, Yan KK, Li S, Bao HH, et al. Body mass index and risk of gastric cancer: a meta-analysis. Jpn J Clin Oncol. 2014 Sep;44(9):783-91. doi: 10.1093/jjco/hyu082
64. Kuipers EJ. Pernicious anemia, atrophic gastritis, and the risk of cancer. Clin Gastroenterol Hepatol. 2015;13:2290-2 doi: 10.1016/j.cgh.2015.07.013
65. Morton LM, Dores GM, Curtis RE, Lynch CF, Stovall M, Hall P, et al. Stomach cancer risk after treatment for hodgkin lymphoma. J Clin Oncol. 2013 Sep 20;31(27):3369-77. doi: 10.1200/JCO.2013.50.6832
66. Ohyauchi M, Imatani A, Yonechi M, Asano N, Miura A, Iijima K., Koike T, et al. The polymorphism interleukin 8 −251 A/T influences the susceptibility of Helicobacter pylori related gastric diseases in the Japanese population. Gut. 2005;54(3):330-5.
67. Yin YW, Hu AM, Sun QQ, Zhang BB, Wang Q, Liu HL, et al. Association between interleukin-8 gene −251 T/A polymorphism and the risk of peptic ulcer disease: a meta-analysis. Hum Immunol. 2013;74(1):125-30.
68. Ramis IB, Vianna JS, Gonçalves CV, von Groll A, Dellagostin OA, da Silva PEA. Polymorphisms of the IL-6, IL-8 and IL-10 genes and the risk of gastric pathology in patients infected with Helicobacter pylori. J Microbiol Immunol Infect. 2017 Apr;50(2):153-9. doi: 10.1016/j.jmii.2015.03.002
Авторы
А.М. Осадчук1, И.Л. Давыдкин1, Т.А. Гриценко1, М.А. Осадчук2
1 ФГБОУ ВО «Самарский государственный медицинский университет» Минздрава России, Самара, Россия;
2 ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский Университет), Москва, Россия
1 Samara State Medical University, Samara, Russia;
2 Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia
1 ФГБОУ ВО «Самарский государственный медицинский университет» Минздрава России, Самара, Россия;
2 ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский Университет), Москва, Россия
________________________________________________
1 Samara State Medical University, Samara, Russia;
2 Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia
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