Цель. Оценка частоты госпитальных сердечно-сосудистых событий в группах больных со стабильной стенокардией, перенесших до коронарного шунтирования (КШ) плановые чрескожные коронарные вмешательства (ЧКВ) со стентированием артерий либо не имевших предшествующей реваскуляризации миокарда. Материалы и методы. Обследованы 120 больных со стабильной стенокардией, перенесших плановое КШ, из них мужчин – 80,8%. Средний возраст – 58+7,6, длительность ишемической болезни сердца – 6+5,7 года. Ранее перенесли инфаркт миокарда (ИМ) 77,5% лиц. Артериальная гипертония имелась у 92,5%, сахарный диабет – у 12,5% больных. Многососудистое коронарное поражение выявлено у 72,5% пациентов, 28 (23,4%) больных ранее перенесли ЧКВ со стентированием артерий. Срок от ЧКВ до КШ составил 20+32,6 мес. Операция КШ в условиях искусственного кровообращения выполнена у 88,3%, на работающем сердце – у 11,7% больных. Число дистальных анастомозов составляло от 1 до 4. Результаты. Между группами больных, перенесших до КШ ЧКВ и без таковых, не выявлено различий по клинико-ангиографическим показателям, фармакотерапии, характеристикам операции. Между анализируемыми группами больных не обнаружено различий в частоте случаев сердечной смерти (0 и 1,1%; р=0,58), нефатального ИМ (3,6 и 9,8%; р=0,29), инсульта (0 и 1,1%; р=0,58), острой сердечной недостаточности (17,3 и 34,8%; р=0,06), числу пациентов с вновь возникшими пароксизмами фибрилляции предсердий (28,6 и 17,4%; р=0,19), доле лиц с рестернотомиями (3,6 и 3,3%; р=0,94) и желудочно-кишечными кровотечениями (3,6 и 4,3%; р=0,86). Заключение. Плановые ЧКВ со стентированием артерий, предшествующие КШ, не оказывают влияния на частоту послеоперационных госпитальных сердечно-сосудистых и геморрагических осложнений.
Ключевые слова: коронарное шунтирование, чрескожное коронарное вмешательство, сердечно-сосудистые события
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Aim. Evaluation of the frequency hospital cardiovascular events in groups of patients with stable angina who underwent percutaneous coronary interventions (PCI) with stenting of the arteries before coronary bypass surgery, or who did not have previous myocardial revascularization. Materials and methods. The 120 patients with stable angina who underwent routine coronary artery bypass grafting were examined. Group composition: Men 80.8%, age – 58±7.6, duration of coronary heart disease – 6±5.7 years, history of myocardial infarction (MI) 77.5%. Arterial hypertension was present in 92.5%, diabetes mellitus in 12.5% of patients. Multivessel coronary artery disease in 72.5% of patients. 28 (23.4%) patients had previously undergone PCI with stenting of the coronary arteries. The period from PCI to coronary bypass surgery was 20±32.6 months. Coronary bypass surgery on-pump was performed in 88.3%, coronary bypass surgery on off-pump in 11.7%. The number of distal anastomoses ranged from 1 to 4. Results. There were no differences in clinical and angiographic indicators, pharmacotherapy, and operation characteristics between the groups of patients who were subjected to or did not have PCI before coronary bypass surgery. There were no differences between the analyzed groups of patients in the frequency of cardiac death (0 and 1.1%, p=0.58), non-fatal MI (3.6% and 9.8%, p=0.29), stroke (0 and 1.1%, p=0.58), acute heart failure (11.7% and 34.8%, p=0.06), the number of patients with paroxysms of atrial fibrillation (28.6% and 17.4%, p=0.94), the proportion of patients with resternotomies (3.6% and 3.3%, p=0.94) and gastrointestinal bleeding (3.6% and 4.3%, p=0.86). Conclusion. PCI with coronary artery stenting, prior to coronary bypass surgery, does not affect the frequency of post-operative hospital cardiovascular and hemorrhagic complications.
1. Hadadzadeh M, Mirahmadi M, Mirzaei M, et al. Comparison of short-term results between patients undergoing coronary artery bypass graft with a stent-placement history and patients undergoing primary coronary artery surgery. J Tehran Univ Hear Cent. 2019;14(2):53-8. DOI:10.18502/jthc.v14i2.1371
2. Stevens L-M, Khairy P, Agnihotri AK. Coronary Artery Bypass Grafting After Recent or Remote Percutaneous Coronary Intervention in the Commonwealth of Massachusetts. Circ Cardiovasc Interv. 2010;3(5):460-7. DOI:10.1161/CIRCINTERVENTIONS.109.901637
3. Biancari F, Mariscalco G, Rubino AS, et al. The effect of prior percutaneous coronary intervention on the immediate and late outcome after coronary artery bypass grafting: systematic review and meta-analysis. Heart Lung Vessel. 2014;6(4):244-52.
4. Рекомендации ESC/EACTS по реваскуляризации миокарда. 2014. Российский кардиологический журнал. 2015;2:5-81 [ESC/EACTS guidelines on myocardial revascularization. 2014. Russian Journal of Cardiology. 2015;2:5-81 (in Russian)]. DOI:10.15829/1560-4071-2015-2-5-81
5. 2014 ESC/EACTS Guidelines on myocardial revascularization. Eur Heart J. 2014;35(37):2541-619. doi:10.1093/eurheartj/ehu278
6. Ellis SG, Vandormael MG, Cowley MJ, et al. Coronary morphologic and clinical determinants of procedural outcome with angioplasty for multivessel coronary disease. Implications for patient selection. Multivessel Angioplasty Prognosis Study Group. Circulation. 1990;82(4):1193-202. DOI:10.1161/01.CIR.82.4.1193
7. Thygesen K, Alpert JS, Jaffe AS, et al. Fourth universal definition of myocardial infarction (2018). Eur Heart J. 2019;40(3):237-69. DOI:10.1093/eurheartj/ehy462
8. Hassan A, Buth KJ, Baskett RJF, et al. The association between prior percutaneous coronary intervention and short-term outcomes after coronary artery bypass grafting. Am Heart J. 2005;150(5):1026-31. DOI:10.1016/j.ahj.2005.03.035
9. Gurbuz AT, Sasmazel A, Cui H, et al. Previous percutaneous coronary intervention may increase symptom recurrence and adverse cardiac events following surgical revascularization. Anadolu Kardiyol Derg. 2006;6(2):148-52.
10. Емельянов А.В. Эффективность тактики микрохирургического коронарного шунтирования у пациентов с рецидивом стенокардии после стентирования коронарных артерий. Автореф. дис. … канд. мед. наук. М., 2016. Режим доступа: http://cardioweb.ru/files/autoref/205/avtoref.pdf. Ссылка активна на 07.07.2022 [Emel'ianov AV. Effektivnost' taktiki mikrokhirurgicheskogo koronarnogo shuntirovaniia u patsientov s retsidivom stenokardii posle stentirovaniia koronarnykh arterii. Avtoref. dis. … kand. med. nauk. Moscow, 2016 (in Russian)]. Available at: http://cardioweb.ru/files/autoref/205/avtoref.pdf. Accessed: 07.07.2022.
11. Yap CH, Yan BP, Akowuah E, et al. Does prior percutaneous coronary intervention adversely affect early and midterm survival after coronary artery surgery? JACC Cardiovasc Interv. 2009;2(8):758-64. DOI:10/1016/j.jcin.2009.04.018
12. Eifert S, Mair H, Boulesteix AL, et al. Mid-term outcomes of patients with PCI prior to CABG in comparison to patients with primary CABG. Vasc Health Risk Manag. 2010;6:495-501. DOI:10.2147/vhrm.s8560
13. Sakaguchi G, Shimamoto T, Komiya T. Impact of repeated percutaneous coronary intervention on long-term survival after subsequent coronary artery bypass surgery. J Cardiothorac Surg. 2011;6(1):107. DOI:10.1186/1749-8090-6-107
14. Lisboa LAF, Mejia OA, Dallan LA, et al. Intervenção Coronariana Percutânea prévia como fator de risco para Revascularização Miocárdica. Arq Bras Cardiol. 2012;99(1):586-95. DOI:10.1590/S0066-782X2012005000057
15. Ирасханов А.К. Коронарное шунтирование у больных после транслюминальной баллонной ангиопластики и стентирования коронарных артерий. Автореф. дис. … канд. мед. наук. М., 2013. Режим доступа: http://www.dissercat.com./content/aortokoronarnoe-shuntirovanie--u-bolnykh-posle-translyuminalnoi-ba.... Ссылка активна на 07.07.2022 [Iraskhanov AK. Koronarnoe shuntirovanie u bol'nykh posle transliuminal'noi ballonnoi angioplastiki i stentirovaniia koronarnykh arterii. Avtoref. dis. … kand. med. nauk. Moscow, 2013. Available at: http://www.dissercat.com./content/aortokoronarnoe-shuntirovanie--u-bolnykh-posle-translyuminalnoi-ba.... Accessed: 07.07.2022 (in Russian)].
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1. Hadadzadeh M, Mirahmadi M, Mirzaei M, et al. Comparison of short-term results between patients undergoing coronary artery bypass graft with a stent-placement history and patients undergoing primary coronary artery surgery. J Tehran Univ Hear Cent. 2019;14(2):53-8. DOI:10.18502/jthc.v14i2.1371
2. Stevens L-M, Khairy P, Agnihotri AK. Coronary Artery Bypass Grafting After Recent or Remote Percutaneous Coronary Intervention in the Commonwealth of Massachusetts. Circ Cardiovasc Interv. 2010;3(5):460-7. DOI:10.1161/CIRCINTERVENTIONS.109.901637
3. Biancari F, Mariscalco G, Rubino AS, et al. The effect of prior percutaneous coronary intervention on the immediate and late outcome after coronary artery bypass grafting: systematic review and meta-analysis. Heart Lung Vessel. 2014;6(4):244-52.
4. ESC/EACTS guidelines on myocardial revascularization. 2014. Russian Journal of Cardiology. 2015;2:5-81 (in Russian). DOI:10.15829/1560-4071-2015-2-5-81
5. 2014 ESC/EACTS Guidelines on myocardial revascularization. Eur Heart J. 2014;35(37):2541-619. doi:10.1093/eurheartj/ehu278
6. Ellis SG, Vandormael MG, Cowley MJ, et al. Coronary morphologic and clinical determinants of procedural outcome with angioplasty for multivessel coronary disease. Implications for patient selection. Multivessel Angioplasty Prognosis Study Group. Circulation. 1990;82(4):1193-202. DOI:10.1161/01.CIR.82.4.1193
7. Thygesen K, Alpert JS, Jaffe AS, et al. Fourth universal definition of myocardial infarction (2018). Eur Heart J. 2019;40(3):237-69. DOI:10.1093/eurheartj/ehy462
8. Hassan A, Buth KJ, Baskett RJF, et al. The association between prior percutaneous coronary intervention and short-term outcomes after coronary artery bypass grafting. Am Heart J. 2005;150(5):1026-31. DOI:10.1016/j.ahj.2005.03.035
9. Gurbuz AT, Sasmazel A, Cui H, et al. Previous percutaneous coronary intervention may increase symptom recurrence and adverse cardiac events following surgical revascularization. Anadolu Kardiyol Derg. 2006;6(2):148-52.
10. Emel'ianov AV. Effektivnost' taktiki mikrokhirurgicheskogo koronarnogo shuntirovaniia u patsientov s retsidivom stenokardii posle stentirovaniia koronarnykh arterii. Avtoref. dis. … kand. med. nauk. Moscow, 2016 (in Russian). Available at: http://cardioweb.ru/files/autoref/205/avtoref.pdf. Accessed: 07.07.2022.
11. Yap CH, Yan BP, Akowuah E, et al. Does prior percutaneous coronary intervention adversely affect early and midterm survival after coronary artery surgery? JACC Cardiovasc Interv. 2009;2(8):758-64. DOI:10/1016/j.jcin.2009.04.018
12. Eifert S, Mair H, Boulesteix AL, et al. Mid-term outcomes of patients with PCI prior to CABG in comparison to patients with primary CABG. Vasc Health Risk Manag. 2010;6:495-501. DOI:10.2147/vhrm.s8560
13. Sakaguchi G, Shimamoto T, Komiya T. Impact of repeated percutaneous coronary intervention on long-term survival after subsequent coronary artery bypass surgery. J Cardiothorac Surg. 2011;6(1):107. DOI:10.1186/1749-8090-6-107
14. Lisboa LAF, Mejia OA, Dallan LA, et al. Intervenção Coronariana Percutânea prévia como fator de risco para Revascularização Miocárdica. Arq Bras Cardiol. 2012;99(1):586-95. DOI:10.1590/S0066-782X2012005000057
15. [Iraskhanov AK. Koronarnoe shuntirovanie u bol'nykh posle transliuminal'noi ballonnoi angioplastiki i stentirovaniia koronarnykh arterii. Avtoref. dis. … kand. med. nauk. Moscow, 2013. Available at: http://www.dissercat.com./content/aortokoronarnoe-shuntirovanie--u-bolnykh-posle-translyuminalnoi-ba.... Accessed: 07.07.2022 (in Russian).