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Язвенный колит и аутоиммунный увеит. Клиническое наблюдение
DOI: 10.26442/00403660.2024.02.202577
© ООО «КОНСИЛИУМ МЕДИКУМ», 2024 г.
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Kagramanova AV, Tankovskiy VE, Demchenko AN, Knyazev OV, Parfenov AI. Ulcerative colitis and autoimmune uveitis. Case report. Terapevticheskii Arkhiv (Ter. Arkh.). 2024;96(2):143–146.
DOI: 10.26442/00403660.2024.02.202577
Материалы доступны только для специалистов сферы здравоохранения. Авторизуйтесь или зарегистрируйтесь.
Ключевые слова: воспалительные заболевания кишечника, язвенный колит, внекишечные проявления, увеит, адалимумаб
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The article provides information on the pathogenesis, classification and frequency of ophthalmic extra-intestinal manifestations in patients with inflammatory bowel diseases (IBD). A clinical observation of a patient with autoimmune uveitis and IBD is described, demonstrating the importance of early diagnosis of immuno-inflammatory diseases in the implementation of multidisciplinary management of patients with IBD and extraintestinal manidestations. The use of genetically engineered biological drugs helps to control the course of IBD, ophthalmic manifestations and prevents the development of complications.
Keywords: inflammatory bowel disease, ulcerative, colitis, extraintestinal manifestations, uveitis, adalimumab
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1. Kniazev OV, Parfenov AI, Kagramanova AV, et al. Diagnostika i lecheniie iazvennogo kolita: uchebnoie posobiie. Moscow: Vita-Press, 2023 (in Russian).
2. Banares AA, Jover JA, Fernandez-Guiterrez JL. Bowel inflammation in anterior uveitis and spondylarthropathy. J Rheumatol. 1995;22:1112-7.
3. Lyons JL, Rosenbaum JT. Uveitis associated with inflammatory bowel disease compared with uveitis associated with spondylarthropathy. Arch Ophthalmol. 1997;115:61-4. DOI:10.1001/archopth.1997.01100150063010
4. Horai R, Zarate-Blades CR, Dillenburg-Pilla P, et al. Microbiota-Dependent Activation of an Autoreactive T Cell Receptor Provokes Autoimmunity in an Immunologically Privileged Site. Immunity. 2015;43:343-53. DOI:10.1016/j.immuni.2015.07.014
5. Crohn BB. Ocular lesions complicating ulcerative colitis. Am J Med Sci. 1925;3:335-52. DOI:10.3748/wjg.v23.i32.5836
6. Das KM. Relationship of extraintestinal involvements in inflammatory bowel disease: new insights into autoimmune pathogenesis. Dig Dis Sci. 1999;44:1-13. DOI:10.1023/a:1026629528233
7. Vavricka SR, Schoepfer A, Scharl M. Extraintestinal manifestations of inflammatory bowel disease. Inflamm Bowel Dis. 2015;21:1982-92. DOI:10.1097/MIB.0000000000000392
8. Hedin CRH, Vavricka SR, Stagg AJ, et al. The Pathogenesis of Extraintestinal Manifestations: Implications for IBD Research, Diagnosis, and Therapy. J Crohn's Colitis. 2018;13:541-54. DOI:10.1093/ecco-jcc/jjy191
9. Schulman MF, Sugar A. Peripheral corneal infiltrates in inflammatory bowel disease. Ann Ophthalmol. 1981;13:109-13.
10. Walker JC, Selva D, Pietrus G. Optic disc swelling in Crohn’s disease. Aust NZJ Ophthalmol. 1998;26:329-32. DOI:10.1111/j.1442-9071.1998.tb01338
11. Salmi M, Jalkanen S. Endothelial ligands and homing of mucosal leukocytes in extraintestinal manifestations of IBD. Inflamm Bowel Dis. 1998;4:149-56. DOI:10.1002/ibd.3780040210
12. Parfenov AI, Knyazev OV, Kagramanova AV. Systemic manifestations of inflammatory bowel diseases. Terapevticheskii Arkhiv (Ter. Arkh.). 2020;2:4-11 (in Russian). DOI:10.26442/00403660.2020.02.000535
13. Neroiev VV, Tankovskii VE. Uveity (osnovnyie simptomy, lecheniie). Moscow: Triumf, 2019 (in Russian).
1ГБУЗ «Московский клинический научно-практический центр им. А.С. Логинова» Департамента здравоохранения г. Москвы, Москва, Россия;
2ГБУ «Научно-исследовательский институт организации здравоохранения и медицинского менеджмента» Департамента здравоохранения г. Москвы, Москва, Россия;
3ФГБУ «Национальный медицинский исследовательский центр глазных болезней им. Гельмгольца» Минздрава России, Москва, Россия;
4ФГБУ «Национальный медицинский исследовательский центр колопроктологии им. А.Н. Рыжих» Минздрава России, Москва, Россия
*asfold@mail.ru
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Anna V. Kagramanova1,2, Vladimir E. Tankovskiy3, Aleksandra N. Demchenko1, Oleg V. Knyazev1,4, Asfold I. Parfenov*1
1Loginov Moscow Clinical Scientific Center, Moscow, Russia;
2Research Institute of Health Organization and Medical Management, Moscow, Russia;
3Helmholtz National Medical Research Center for Eye Diseases, Moscow, Russia;
4Ryzikh National Medical Research Centre for Coloproctology, Moscow, Russia
*asfold@mail.ru