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Фиксированные комбинации гипогликемических препаратов: возможности алоглиптина/пиоглитазона при сахарном диабете 2-го типа - Журнал Терапевтический архив №8 Вопросы лечения 2025
Фиксированные комбинации гипогликемических препаратов: возможности алоглиптина/пиоглитазона при сахарном диабете 2-го типа
Бутранова О.И., Зырянов С.К., Мельникова А.Р., Мацепуро А.Е. Фиксированные комбинации гипогликемических препаратов: возможности алоглиптина/пиоглитазона при сахарном диабете 2-го типа. Терапевтический архив. 2025;97(8):735–749. DOI: 10.26442/00403660.2025.08.203345
© ООО «КОНСИЛИУМ МЕДИКУМ», 2025 г.
© ООО «КОНСИЛИУМ МЕДИКУМ», 2025 г.
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Аннотация
Сахарный диабет 2-го типа – одно из наиболее распространенных хронических заболеваний, являющихся фактором риска возникновения широкого круга осложнений. Внедрение в клиническую практику подхода, состоящего в раннем назначении комбинированной сахароснижающей терапии, делает актуальным изучение доступных фиксированных комбинаций гипогликемических препаратов. Алоглиптин и пиоглитазон представляют интерес с точки зрения комплексного воздействия на организм пациента при их совместном использовании. Цель настоящего обзора – оценка преимуществ комбинации алоглиптина и пиоглитазона на основе анализа опубликованных данных фармакодинамики, фармакокинетики, эффективности и безопасности указанных препаратов.
Ключевые слова: фиксированная комбинация гипогликемических препаратов, сахарный диабет, алоглиптин, пиоглитазон, сердечно-сосудистое заболевание, хроническая болезнь почек
Keywords: fixed-dose combinations of hypoglycemic drugs, diabetes mellitus, alogliptin, pioglitazone, cardiovascular diseases, chronic kidney disease
Ключевые слова: фиксированная комбинация гипогликемических препаратов, сахарный диабет, алоглиптин, пиоглитазон, сердечно-сосудистое заболевание, хроническая болезнь почек
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Keywords: fixed-dose combinations of hypoglycemic drugs, diabetes mellitus, alogliptin, pioglitazone, cardiovascular diseases, chronic kidney disease
Полный текст
Список литературы
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Авторы
О.И. Бутранова*1, С.К. Зырянов1,2, А.Р. Мельникова1, А.Е. Мацепуро1
1ФГАОУ ВО «Российский университет дружбы народов им. Патриса Лумумбы», Москва, Россия;
2ГБУЗ г. Москвы «Городская клиническая больница №24» Департамента здравоохранения г. Москвы, Москва, Россия
*butranova-oi@rudn.ru
1Peoples' Friendship University of Russia named after Patrice Lumumba, Moscow, Russia;
2City Clinical Hospital No. 24, Moscow, Russia
*butranova-oi@rudn.ru
1ФГАОУ ВО «Российский университет дружбы народов им. Патриса Лумумбы», Москва, Россия;
2ГБУЗ г. Москвы «Городская клиническая больница №24» Департамента здравоохранения г. Москвы, Москва, Россия
*butranova-oi@rudn.ru
________________________________________________
1Peoples' Friendship University of Russia named after Patrice Lumumba, Moscow, Russia;
2City Clinical Hospital No. 24, Moscow, Russia
*butranova-oi@rudn.ru
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