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Медикаментозные средства в реабилитации больных после инфаркта миокарда: ингибиторы ангиотензинпревращающего фермента
Медикаментозные средства в реабилитации больных после инфаркта миокарда: ингибиторы ангиотензинпревращающего фермента
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Аннотация
В работе проведен анализ применения ангиотензинпревращающего фермента (ИАПФ) у больных после перенесенного инфаркта миокарда (ИМ). Представлены данные контролируемых исследований, показывающих обоснованность применения ИАПФ для улучшения прогноза больных. Сделан вывод о том, что неназначение врачом ИАПФ больным после ИМ с явной или бессимптомной дисфункцией левого желудочка, а также больным сахарным диабетом (при отсутствии противопоказаний) является неоправданным.
Ключевые слова: ингибиторы ангиотензинпревращающего фермента, инфаркт миокарда, сердечная недостаточность.
Key words: angiotensin-converting enzyme inhibitors, myocardial infarction, heart failure.
Ключевые слова: ингибиторы ангиотензинпревращающего фермента, инфаркт миокарда, сердечная недостаточность.
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Key words: angiotensin-converting enzyme inhibitors, myocardial infarction, heart failure.
Полный текст
Список литературы
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12. MacMurray J, Cohen-Solal A, Dietz R et al. Practical recommendations for the use of ACE inhibitors, beta-blockers and spironolactone in heart failure: putting guidelines into practice. Eur J Heart Failure 2001; 3: 495–502.
2. Pfeffer JM, Pfeffer M, Braunwald E. Influence of chronic captopril therapy on the infarcted left ventricle of the rat. Circ Res 1985; 57: 84–95.
3. Pfeffer MA, Braunwald EA, Moyé LA et al. Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction: results of the Survival And Ventricular Enlargement trial. N Engl J Med 1992; 327: 669–77.
4. De Kam PJ, Voors AA et al. Effect of very early angiotensin-converting enzyme inhibition on left ventricular dilatation after myocardial infarction in patients receiving thrombolysis. J Am Coll Cardiol 2000; 36: 2047–53.
5. Gruppo Italiano per lo Studio della Sopravvivenza nell’Infarto miocardico. The prognostic value of predischarge quantitative two-dimensional echocardiographyc measurements and the effects of early lisinopril treatment on left ventricular structure and function after acute myocardial infarction in the GISSI-3 trial. Eur Heart J 1996; 17: 1646–56.
6. Greenberg B, Quinones MA et al. Effects of long-term enalapril therapy on cardiac structure and function in patients with left netricular dysfunction. Results of the SOLVD Echocardiographic Study. Circulation 1995; 91: 2573–81.
7. Study Investigators. Effect of ramipril on mortality and morbidity of survivors of acute myocardial infarction with clinical evidence of heart failure. The Acute Infarction Ramipril Efficacy. Lancet 1993; 342: 821–8.
8. Kober L, Torp-Pedersen C, Carlsen JE et al. for the trandolapril cardiac evaluation (TRACE) study group: a clinical trial of the angiotensin converting enzyme inhibitor trandolapril in patients with left ventricular dysfunction after myocardial infarction. N Engl J Med 1995; 33: 1670–6.
9. Kang PM, Landau AJ, Eberhardt RT, Frishman WH. Angiotensin II receptor antagonists: a new approach to blockade of the renin-angiotensin system Am Heart J 1994; 127: 1388–401.
10. Ferner RE, Simpson JM, Rawlins MD. Effects of intradermal bradykininn after inhibition of angiotensin converting enzyme. Br Med J 1987; 294: 1119–20.
11. Expert consensus document on angiotensin converting enzyme inhibitors in cardiovascular disease. Eur Heart J 2004; 25: 1454–70.
12. MacMurray J, Cohen-Solal A, Dietz R et al. Practical recommendations for the use of ACE inhibitors, beta-blockers and spironolactone in heart failure: putting guidelines into practice. Eur J Heart Failure 2001; 3: 495–502.
Авторы
А.С.Галявич
Казанский государственный медицинский университет
Kazan State Medical University
Казанский государственный медицинский университет
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Kazan State Medical University
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