В связи с успехами кардиологии и увеличением продолжительности жизни населения распространенность хронической сердечной недостаточности неуклонно растет. Это, в свою очередь, приводит к увеличению абсолютного числа пациентов, у которых недостаточно эффективна оптимально назначенная медикаментозная терапия. В этом случае пациентам с хронической сердечной недостаточностью II–IV функционального класса с выраженной систолической дисфункцией левого желудочка и расширенным комплексом QRS показана сердечная ресинхронизирующая терапия (CРТ). Несмотря на тщательный отбор пациентов для СРТ, почти в 1/3 случаев устройство не приводит к ожидаемому результату. Для увеличения эффективности данного вмешательства процедуру необходимо выполнять строго в соответствии с актуальными клиническими рекомендациями только комплаентным пациентам, находящимся не менее 3 мес на подобранной оптимальной медикаментозной терапии, использовать оптимальные стратегии и режимы стимуляции. Число пациентов с долгосрочным использованием СРТ прогрессивно увеличивается. Все больше пациентов с установленными устройствами попадают в поле зрения врачей-терапевтов и кардиологов поликлиник и стационаров, для которых крайне важно понимать особенности методики и тактики ведения таких пациентов. Этому посвящена данная публикация.
Ключевые слова: хроническая сердечная недостаточность, сердечная ресинхронизирующая терапия, имплантируемый кардиовертер-дефибриллятор, сердечная ресинхронизирующая терапия с функцией дефибриллятора, оптимальная медикаментозная терапия, прогноз, качество жизни, фракция выброса левого желудочка.
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The prevalence of the chronic heart failure is increasing due to the success of cardiology and the increase in life expectancy of the population. A greater number of patients live up to the clinically pronounced stages of the chronic heart failure. This issue leads to an increasing in the absolute number of the patients in whom there is a lack of efficacy of optimally prescribed drug therapy. These patients are considering initiating cardiac resynchronization therapy (CRT). CRT is recommended for the patients with chronic heart failure II–IV functional class with severe left ventricular systolic dysfunction and prolonged QRS complex. Despite careful selection of patients for CRT implantation, the device does not lead to the expected result in one third of cases. To increase the effectiveness of this intervention, the procedure should be performed in accordance with current guidelines only for compliant patients who have been at least 3 months on selected optimal drug therapy, should use the optimal strategies and modes of stimulation and the adequate drug support after the intervention. The number of patients with long-term use of CRT is constantly growing. More and more patients with installed devices come into the field of vision of general practitioners and cardiologists of ambulatory clinics and hospitals, for whom it is extremely important to understand the specifics of the methods and tactics of managing such patients. This publication is dedicated to this.
Key words: chronic heart failure, cardiac resynchronization therapy, implantable cardioverter-defibrillator, optimal drug therapy, prognosis, quality of life, left ventricular ejection fraction.
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1 ФГБОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России, Москва, Россия;
2 ФГБУ «Национальный медицинский исследовательский центр кардиологии» Минздрава России, Москва, Россия
*elenaresnik@gmail.com
________________________________________________
Elena V. Reznik*1, Semen Yu. Soltis1, Dmitrii V. Ustiuzhanin2, Igor G. Nikitin1
1 Pirogov Russian National Research Medical University, Moscow, Russia;
2 National Medical Research Center of Cardiology, Moscow, Russia
*elenaresnik@gmail.com