Позаконазол – новый азольный антимикотик широкого спектра для профилактики и лечения инвазивных микозов
Позаконазол – новый азольный антимикотик широкого спектра для профилактики и лечения инвазивных микозов
Климко Н.Н. Позаконазол – новый азольный антимикотик широкого спектра для профилактики и лечения инвазивных микозов. Consilium Medicum. 2008; 10 (1): 18–25.
Материалы доступны только для специалистов сферы здравоохранения.
Чтобы посмотреть материал полностью
Авторизуйтесь
или зарегистрируйтесь.
Список литературы
1. Clark TA, Hajjeh RA. Recent trends in the epidemiology of invasive mycoses. Curr Opin Infect Dis 2002; 15: 569–74.
2. Hayes-Lattin B, Maziarz RT. Update in the epidemiology, prophylaxis, and treatment of fungal infections in patients with hematologic disorders. Leuk Lymphoma 2004; 45: 669–80.
3. Климко Н.Н., Веселов А.В. Новые препараты для лечения инвазивных микозов. Клинич. микробиол. и антимикроб. химиотер. 2003; 5: 342–53.
4. Dodds Ashley E, Alexander B. Posaconazole. Drugs Today 2005; 41 (6): 393–400.
5. Groll A, Walsh T. Posaconazole: clinical pharmacology and potential for management of fungal infections. Expert Rev Anti Infect Ther 2005; 3 (4): 467–87.
6. Boucher H, Groll A, Chiou C et al. Newer systemic antifungal agents: pharmacokinetics, safety and efficacy. Drugs 2004; 64 (18): 1997–2020.
7. Andes D, Marchillo K, Conklin R et al. Pharmacodynamics of a new triazole, posaconazole, in a murine model of disseminated candidiasis. Antimicrob Agents Chemother 2004; 48 (1): 137–42.
8. Pfaller M, Messer S, Hollis R et al. Antifungal activities of posaconazole, ravuconazole, and voriconazole compared to those of itraconazole and amphotericin B against 239 clinical isolates of Aspergillus spp. and other filamentous fungi: report from SENTRY Antimicrobial Surveillance Program, 2000. Antimicrob Agents Chemother 2002; 46 (4): 1032–7.
9. Sabatelli F, Patel R, Mann P et al. In vitro activities of posaconazole, fluconazole, itraconazole, voriconazole, and amphotericin B against a large collection of clinically important molds and yeasts. Antimicrob Agents Chemother 2006; 50 (6): 2009–15.
10. Torres-Narbona M, Guinea J, Martinez-Alarcon J et al. In Vitro Activities of Amphotericin B, Caspofungin, Itraconazole, Posaconazole, and Voriconazole against 45 Clinical Isolates of Zygomycetes: Comparison of CLSI M38-A, Sensititre YeastOne, and the Etest. Antimicrob Agents Chemother 2007; 51 (3): 1126–9.
11. Torres H, Hachem R, Chemaly R et al. Posaconazole: a broad-spectrum triazole antifungal. Lancet Infect Dis 2005; 5 (12): 775–85.
12. Courtney R, Pai S, Laughlin M et al. Pharmacokinetics, safety, and tolerability of oral posaconazole administered in single and multiple doses in healthy adults. Antimicrob Agents Chemother 2003; 47 (9): 2788–95.
13. Conte JR, Golden JA, Krishna G et al. Intra pulmonary ppharmacokinetics-pharmacodynamics of posaconazole. 3 Advancer Against Aspergillosis. 2008.
14. Krieter P, Flannery B, Musick T et al. Disposition of posaconazole following single-dose oral administration in healthy subjects. Antimicrob Agents Chemother 2004; 48 (9): 3543–51.
15. Wexler D, Courtney R, Richards W et al. Effect of posaconazole on cytochrome P450 enzymes: a randomized, open-label, two-way crossover study. Eur J Pharm Sci 2004; 21 (5): 645–53.
16. Sansone-Parsons A, Krishna G, Simon J et al. Effects of age, gender, and race/ethnicity on the pharmacokinetics of posaconazole in healthy volunteers. Antimicrob Agents Chemother 2007; 51 (2): 495–502.
17. Naggapan V, Deresinski S. Posaconazole: a broad-spectrum triazole antifungal agent. Clin infect Dis 2007; 45: 1610–7.
18. Ullmann A, Cornely O, Burchardt A et al. Pharmacokinetics, safety, and efficacy of posaconazole in patients with persistent febrile neutropenia or refractory invasive fungal infection. Antimicrob Agents Chemother 2006; 50 (2): 658–66.
19. Krishna G, Sansone-Parsons A, Martinho M et al. Posaconazole Plasma Concentrations in Juvenile Patients With Invasive Fungal Infection. Antimicrob Agents Chemother 2007; 51 (3): 812–8.
20. Antachopoulos C, Walsh T. New agents for invasive mycoses in children. Curr Opin Pediatr 2005; 17 (1): 78–87.
21. Keating G. Posaconazole. Drugs. 2005 65 (11): 1553–67.
22. Pitisuttithum P, Negroni R, Graybill J et al. Activity of posaconazole in the treatment of central nervous system fungal infections. J Antimicrob Chemother 2005; 56 (4): 745–55.
23. Tobon A, Arango M, Fernandez D et al. Mucormycosis (zygomycosis) in a heart-kidney transplant recipient: recovery after posaconazole therapy. CID. 20031; 36 (11): 1488–91.
24. Greenberg R, Mullane K, van Burik J et al. Posaconazole as salvage therapy for Zygomycosis. Antimicrob Agents Chemother 2006; 50 (1): 126–33.
25. van Burik J, Hare R, Solomon H et al. Posaconazole is effective as salvage therapy in zygomycosis: a retrospective summary of 91 cases. CID 2006; 42 (7): 61–5.
26. Rutar T, Cockerham K. Periorbital zygomycosis (mucormycosis) treated with posaconazole. Am J Ophthalmol 2006; 142 (1): 187–8.
27. Page R, Schwiesow J, Hilts A. Posaconazole as salvage therapy in a patient with disseminated zygomycosis: case report and review of the literature. Pharmacotherapy 2007; 27 (2): 290–8.
28. Walsh T, Raad I, Patterson T et al. Treatment of invasive aspergillosis with posaconazole in patients who are refractory to or intolerant of conventional therapy: an externally controlled trial. CID 2007; 44 (1): 2–12.
29. Raad I, Hachem R, Herbrecht R et al. Posaconazole as salvage treatment for invasive fusariosis in patients with underlying hematologic malignancy and other conditions. CID. 2006; 42 (10): 1398–403.
30. Tu E, McCartney D, Beatty R et al. Successful Treatment of Resistant Ocular Fusariosis With Posaconazole (SCH-56592). Am J Ophthalmol 2007; 143 (2): 222–7.
31. Restrepo A,Tobon A, Clark B et al. Salvage treatment of histoplasmosis with posaconazole. J Infect 2007; 54 (4): 319–27.
32. Ullmann A, Cornely O. Antifungal prophylaxis for invasive mycoses in high risk patients. Curr Opin Infect Dis 2006; 19 (6): 571–6.
33. Barchiesi F, Spreghini E, Santinelli A et al. Posaconazole prophylaxis in experimental systemic zygomycosis. Antimicrob Agents Chemother 2007; 51 (1): 73–7.
34. Cornely O, Maertens J, Winston D et al. Posaconazole vs. fluconazole or itraconazole prophylaxis in patients with neutropenia. N Engl J Med 2007; 356 (4): 348–59.
35. Ullmann A, Lipton J, Vesole D et al. Posaconazole or fluconazole for prophylaxis in severe graft-versus-host disease. N Engl J Med 2007; 356 (4): 335–47.
36. Notheis G, Tarani L, Costantino F et al. Posaconazole for treatment of refractory invasive fungal disease. Mycoses 2006; 1: 37–41.
37. De Decker K, Van Poucke S, Wojciechowski M et al. Successful use of posaconazole in a pediatric case of fungal necrotizing fasciitis. Pediatr Crit Care Med 2006; 7 (5): 482–5.
38. Sorensen J, Becker M, Porto L et al. Rhinocerebral zygomycosis in a young girl undergoing allogeneic stem cell transplantation for severe aplastic anaemia. Mycoses 2006; 49: 31–6.
39. Chan Y, Goldwater P, Saxon B. Successful treatment of cutaneous and subcutaneous zygomycosis in an immunosuppressed patient with aplastic anaemia. J Paediatr Child Health 2007; 43 (1-2): 87–9.
40. Raad I, Graybill J, Bustamante A et al. Safety of long-term oral posaconazole use in the treatment of refractory invasive fungal infections. CID 2006; 42 (12): 1726–34.
41. Paugam A. The latest data on posaconazole. Med Mal Infect 2007; 54 (4): 319–27.
42. Walsh TJ et al. Treatment of aspergillosis: clinical practice guidelines of the Infectious Disieases Society of America. Clin Infect Dis 2008; 46: 327–60.
43. NCCN Clinical Practice Guidelines in Oncology. 2007; 1. Prevention and Treatment of Cancer-Related Infections. www.nccn.org.
44. Maertens JA et al. Primary antifungal prophylaxis in leukemia patients. Eur J Cancer 2007; 5: 43–9.
45. НОКСАФИЛ – Инструкция по медицинскому применению препарата. 2007.
2. Hayes-Lattin B, Maziarz RT. Update in the epidemiology, prophylaxis, and treatment of fungal infections in patients with hematologic disorders. Leuk Lymphoma 2004; 45: 669–80.
3. Климко Н.Н., Веселов А.В. Новые препараты для лечения инвазивных микозов. Клинич. микробиол. и антимикроб. химиотер. 2003; 5: 342–53.
4. Dodds Ashley E, Alexander B. Posaconazole. Drugs Today 2005; 41 (6): 393–400.
5. Groll A, Walsh T. Posaconazole: clinical pharmacology and potential for management of fungal infections. Expert Rev Anti Infect Ther 2005; 3 (4): 467–87.
6. Boucher H, Groll A, Chiou C et al. Newer systemic antifungal agents: pharmacokinetics, safety and efficacy. Drugs 2004; 64 (18): 1997–2020.
7. Andes D, Marchillo K, Conklin R et al. Pharmacodynamics of a new triazole, posaconazole, in a murine model of disseminated candidiasis. Antimicrob Agents Chemother 2004; 48 (1): 137–42.
8. Pfaller M, Messer S, Hollis R et al. Antifungal activities of posaconazole, ravuconazole, and voriconazole compared to those of itraconazole and amphotericin B against 239 clinical isolates of Aspergillus spp. and other filamentous fungi: report from SENTRY Antimicrobial Surveillance Program, 2000. Antimicrob Agents Chemother 2002; 46 (4): 1032–7.
9. Sabatelli F, Patel R, Mann P et al. In vitro activities of posaconazole, fluconazole, itraconazole, voriconazole, and amphotericin B against a large collection of clinically important molds and yeasts. Antimicrob Agents Chemother 2006; 50 (6): 2009–15.
10. Torres-Narbona M, Guinea J, Martinez-Alarcon J et al. In Vitro Activities of Amphotericin B, Caspofungin, Itraconazole, Posaconazole, and Voriconazole against 45 Clinical Isolates of Zygomycetes: Comparison of CLSI M38-A, Sensititre YeastOne, and the Etest. Antimicrob Agents Chemother 2007; 51 (3): 1126–9.
11. Torres H, Hachem R, Chemaly R et al. Posaconazole: a broad-spectrum triazole antifungal. Lancet Infect Dis 2005; 5 (12): 775–85.
12. Courtney R, Pai S, Laughlin M et al. Pharmacokinetics, safety, and tolerability of oral posaconazole administered in single and multiple doses in healthy adults. Antimicrob Agents Chemother 2003; 47 (9): 2788–95.
13. Conte JR, Golden JA, Krishna G et al. Intra pulmonary ppharmacokinetics-pharmacodynamics of posaconazole. 3 Advancer Against Aspergillosis. 2008.
14. Krieter P, Flannery B, Musick T et al. Disposition of posaconazole following single-dose oral administration in healthy subjects. Antimicrob Agents Chemother 2004; 48 (9): 3543–51.
15. Wexler D, Courtney R, Richards W et al. Effect of posaconazole on cytochrome P450 enzymes: a randomized, open-label, two-way crossover study. Eur J Pharm Sci 2004; 21 (5): 645–53.
16. Sansone-Parsons A, Krishna G, Simon J et al. Effects of age, gender, and race/ethnicity on the pharmacokinetics of posaconazole in healthy volunteers. Antimicrob Agents Chemother 2007; 51 (2): 495–502.
17. Naggapan V, Deresinski S. Posaconazole: a broad-spectrum triazole antifungal agent. Clin infect Dis 2007; 45: 1610–7.
18. Ullmann A, Cornely O, Burchardt A et al. Pharmacokinetics, safety, and efficacy of posaconazole in patients with persistent febrile neutropenia or refractory invasive fungal infection. Antimicrob Agents Chemother 2006; 50 (2): 658–66.
19. Krishna G, Sansone-Parsons A, Martinho M et al. Posaconazole Plasma Concentrations in Juvenile Patients With Invasive Fungal Infection. Antimicrob Agents Chemother 2007; 51 (3): 812–8.
20. Antachopoulos C, Walsh T. New agents for invasive mycoses in children. Curr Opin Pediatr 2005; 17 (1): 78–87.
21. Keating G. Posaconazole. Drugs. 2005 65 (11): 1553–67.
22. Pitisuttithum P, Negroni R, Graybill J et al. Activity of posaconazole in the treatment of central nervous system fungal infections. J Antimicrob Chemother 2005; 56 (4): 745–55.
23. Tobon A, Arango M, Fernandez D et al. Mucormycosis (zygomycosis) in a heart-kidney transplant recipient: recovery after posaconazole therapy. CID. 20031; 36 (11): 1488–91.
24. Greenberg R, Mullane K, van Burik J et al. Posaconazole as salvage therapy for Zygomycosis. Antimicrob Agents Chemother 2006; 50 (1): 126–33.
25. van Burik J, Hare R, Solomon H et al. Posaconazole is effective as salvage therapy in zygomycosis: a retrospective summary of 91 cases. CID 2006; 42 (7): 61–5.
26. Rutar T, Cockerham K. Periorbital zygomycosis (mucormycosis) treated with posaconazole. Am J Ophthalmol 2006; 142 (1): 187–8.
27. Page R, Schwiesow J, Hilts A. Posaconazole as salvage therapy in a patient with disseminated zygomycosis: case report and review of the literature. Pharmacotherapy 2007; 27 (2): 290–8.
28. Walsh T, Raad I, Patterson T et al. Treatment of invasive aspergillosis with posaconazole in patients who are refractory to or intolerant of conventional therapy: an externally controlled trial. CID 2007; 44 (1): 2–12.
29. Raad I, Hachem R, Herbrecht R et al. Posaconazole as salvage treatment for invasive fusariosis in patients with underlying hematologic malignancy and other conditions. CID. 2006; 42 (10): 1398–403.
30. Tu E, McCartney D, Beatty R et al. Successful Treatment of Resistant Ocular Fusariosis With Posaconazole (SCH-56592). Am J Ophthalmol 2007; 143 (2): 222–7.
31. Restrepo A,Tobon A, Clark B et al. Salvage treatment of histoplasmosis with posaconazole. J Infect 2007; 54 (4): 319–27.
32. Ullmann A, Cornely O. Antifungal prophylaxis for invasive mycoses in high risk patients. Curr Opin Infect Dis 2006; 19 (6): 571–6.
33. Barchiesi F, Spreghini E, Santinelli A et al. Posaconazole prophylaxis in experimental systemic zygomycosis. Antimicrob Agents Chemother 2007; 51 (1): 73–7.
34. Cornely O, Maertens J, Winston D et al. Posaconazole vs. fluconazole or itraconazole prophylaxis in patients with neutropenia. N Engl J Med 2007; 356 (4): 348–59.
35. Ullmann A, Lipton J, Vesole D et al. Posaconazole or fluconazole for prophylaxis in severe graft-versus-host disease. N Engl J Med 2007; 356 (4): 335–47.
36. Notheis G, Tarani L, Costantino F et al. Posaconazole for treatment of refractory invasive fungal disease. Mycoses 2006; 1: 37–41.
37. De Decker K, Van Poucke S, Wojciechowski M et al. Successful use of posaconazole in a pediatric case of fungal necrotizing fasciitis. Pediatr Crit Care Med 2006; 7 (5): 482–5.
38. Sorensen J, Becker M, Porto L et al. Rhinocerebral zygomycosis in a young girl undergoing allogeneic stem cell transplantation for severe aplastic anaemia. Mycoses 2006; 49: 31–6.
39. Chan Y, Goldwater P, Saxon B. Successful treatment of cutaneous and subcutaneous zygomycosis in an immunosuppressed patient with aplastic anaemia. J Paediatr Child Health 2007; 43 (1-2): 87–9.
40. Raad I, Graybill J, Bustamante A et al. Safety of long-term oral posaconazole use in the treatment of refractory invasive fungal infections. CID 2006; 42 (12): 1726–34.
41. Paugam A. The latest data on posaconazole. Med Mal Infect 2007; 54 (4): 319–27.
42. Walsh TJ et al. Treatment of aspergillosis: clinical practice guidelines of the Infectious Disieases Society of America. Clin Infect Dis 2008; 46: 327–60.
43. NCCN Clinical Practice Guidelines in Oncology. 2007; 1. Prevention and Treatment of Cancer-Related Infections. www.nccn.org.
44. Maertens JA et al. Primary antifungal prophylaxis in leukemia patients. Eur J Cancer 2007; 5: 43–9.
45. НОКСАФИЛ – Инструкция по медицинскому применению препарата. 2007.
Авторы
Н.Н.Климко
Цель портала OmniDoctor – предоставление профессиональной информации врачам, провизорам и фармацевтам.
