Факторы роста в космецевтике: роль в регенерации кожи
Факторы роста в космецевтике: роль в регенерации кожи
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Аннотация
Факторы роста играют важную роль в процессах регенерации возрастных изменений кожи, запускаемых внутренними и внешними факторами, что было показано во многих клинических исследованиях. Применение лечебно-косметических средств с факторами роста улучшает показатели кожи и сокращает выраженность симптомов старения, в том числе отмечается статистически значимое повышение синтеза колла-
гена.
external factors that has been shown in many clinical researches. Application of medical-cosmetic means with growth factors
improves indicators of a skin and reduces expressiveness of symptoms of ageing, including statistically significant
increase of synthesis of collagen is marked.
гена.
________________________________________________
external factors that has been shown in many clinical researches. Application of medical-cosmetic means with growth factors
improves indicators of a skin and reduces expressiveness of symptoms of ageing, including statistically significant
increase of synthesis of collagen is marked.
Список литературы
1. Ansel J, Perry P, Brown J et al. Cytokine modulation of keratinocyte
cytokines. J Invest Dermatol 1990; 94 (6 Suppl.): 101S–7.
2. Brauchle M, Angemeyer K, Hubner G, Werner S. Large induction of keratinocyte
growth factor expression by serum growth factors and pro-inflammatory
cytokines in cultured fibroblasts. Oncogene 1994; 9: 3199–204.
3. El-Domyati M, Attia S, Saleh F et al. Intrinsic aging vs. photoaging: a comparative
histopathological, immunohistochemical, and ultrastructural study
of skin. Exp Dermatol 2002; 11: 398–405.
4. Eming SA, Krieg T, Davidson JM. Inflammation in wound repair: molecular
and cellular mechanisms. J Invest Dermatol 2007; 127: 514–25.
5. Fisher GJ, Wang ZQ, Datta SC et al. Pathophysiology of premature skin
aging induced by ultraviolet light. N Engl J Med 1997; 337: 1419–28.
6. Fitzpatrick RE, Rostan EF. Reversal of photodamage with topical growth
factors: a pilot study. J Cosmet Laser Ther 2003; 5: 25–34.
7. Ghadially R, Brown BE, Sequeira-Martin SM et al. The aged epidermal permeability
barrier. Structural, functional, and lipid biochemical abnormalities
in humans and a senescent murine model. J Clin Invest 1995; 95: 2281–90.
8. Gilchrest BA. Skin aging and photoaging: an overview. J Am Acad Dermatol
1989; 21: 610–3.
9. Hensley K, Floyd R. Reactive oxygen species and protein oxidation in
aging: a look back, a look ahead. Arch Biochem Biophys 2002; 397: 377–83.
10. Martin P. Wound healing – aiming for perfect skin regeneration. Science
1997; 276: 75–81.
11. Oikarinen A. The aging of skin: chronoaging versus photoaging. Photodermatol
Photoimmunol Photomed 1990; 7: 3–4.
12. Omi T, Kawana S, Sato T, Honda M. Ultrastructural changed elicited by a
non-ablative wrinkle reduction laser. Lasers Surg Med 2003; 32: 46–9.
13. Rokhsar CK, Lee S, Fitzpatrick RE. Review of photorejuvenation: devices,
cosmeceuticals or both? Dermatol Surg 2005; 31: 1166–78.
14. Senftleben U, Karin M. The IKK/NF-B pathway. Crit Care Med 2002; 30 (1
Suppl.): S18–26.
15. Schwartz E, Cruickshank FA, Christensen CC et al. Collagen alterations in
chronically sun-damaged human skin. Photochem Photobiol 1993; 53:
841–4.
16. Sohal RS, Weindruch R. Oxidative stress, caloric restriction, and aging. Science
1996; 273: 59–63.
17. Transdermal and Topical Delivery of Therapeutic Peptides and Proteins.
In: Banga AK, ed. Therapeutic peptides and proteins: formulation, processing,
and delivery systems, 2nd ed. Bioca Raton, FL: CRC Press, 2005.
18. Varani J, Warner RL, Gharaee-Kermani M et al. Vitamin A antagonizes
decreased cell growth and elevated collagendegrading matrix metalloproteinases
and stimulates collagen accumulation in naturally aged human
skin. J Invest Dermatol 2000; 114: 480–6.
19. Werner S, Krieg T, Smola H. Keratinocyte-fibroblast interaction in wound
healing. J Invest Dermatol 2007; 127: 998–1008.
20. Yamamoto Y, Gaynor RB. Therapeutic potential of inhibition of the NF-B
pathway in the treatment of inflammation and cancer. J Clin Invest 2001;
107: 135–42.
cytokines. J Invest Dermatol 1990; 94 (6 Suppl.): 101S–7.
2. Brauchle M, Angemeyer K, Hubner G, Werner S. Large induction of keratinocyte
growth factor expression by serum growth factors and pro-inflammatory
cytokines in cultured fibroblasts. Oncogene 1994; 9: 3199–204.
3. El-Domyati M, Attia S, Saleh F et al. Intrinsic aging vs. photoaging: a comparative
histopathological, immunohistochemical, and ultrastructural study
of skin. Exp Dermatol 2002; 11: 398–405.
4. Eming SA, Krieg T, Davidson JM. Inflammation in wound repair: molecular
and cellular mechanisms. J Invest Dermatol 2007; 127: 514–25.
5. Fisher GJ, Wang ZQ, Datta SC et al. Pathophysiology of premature skin
aging induced by ultraviolet light. N Engl J Med 1997; 337: 1419–28.
6. Fitzpatrick RE, Rostan EF. Reversal of photodamage with topical growth
factors: a pilot study. J Cosmet Laser Ther 2003; 5: 25–34.
7. Ghadially R, Brown BE, Sequeira-Martin SM et al. The aged epidermal permeability
barrier. Structural, functional, and lipid biochemical abnormalities
in humans and a senescent murine model. J Clin Invest 1995; 95: 2281–90.
8. Gilchrest BA. Skin aging and photoaging: an overview. J Am Acad Dermatol
1989; 21: 610–3.
9. Hensley K, Floyd R. Reactive oxygen species and protein oxidation in
aging: a look back, a look ahead. Arch Biochem Biophys 2002; 397: 377–83.
10. Martin P. Wound healing – aiming for perfect skin regeneration. Science
1997; 276: 75–81.
11. Oikarinen A. The aging of skin: chronoaging versus photoaging. Photodermatol
Photoimmunol Photomed 1990; 7: 3–4.
12. Omi T, Kawana S, Sato T, Honda M. Ultrastructural changed elicited by a
non-ablative wrinkle reduction laser. Lasers Surg Med 2003; 32: 46–9.
13. Rokhsar CK, Lee S, Fitzpatrick RE. Review of photorejuvenation: devices,
cosmeceuticals or both? Dermatol Surg 2005; 31: 1166–78.
14. Senftleben U, Karin M. The IKK/NF-B pathway. Crit Care Med 2002; 30 (1
Suppl.): S18–26.
15. Schwartz E, Cruickshank FA, Christensen CC et al. Collagen alterations in
chronically sun-damaged human skin. Photochem Photobiol 1993; 53:
841–4.
16. Sohal RS, Weindruch R. Oxidative stress, caloric restriction, and aging. Science
1996; 273: 59–63.
17. Transdermal and Topical Delivery of Therapeutic Peptides and Proteins.
In: Banga AK, ed. Therapeutic peptides and proteins: formulation, processing,
and delivery systems, 2nd ed. Bioca Raton, FL: CRC Press, 2005.
18. Varani J, Warner RL, Gharaee-Kermani M et al. Vitamin A antagonizes
decreased cell growth and elevated collagendegrading matrix metalloproteinases
and stimulates collagen accumulation in naturally aged human
skin. J Invest Dermatol 2000; 114: 480–6.
19. Werner S, Krieg T, Smola H. Keratinocyte-fibroblast interaction in wound
healing. J Invest Dermatol 2007; 127: 998–1008.
20. Yamamoto Y, Gaynor RB. Therapeutic potential of inhibition of the NF-B
pathway in the treatment of inflammation and cancer. J Clin Invest 2001;
107: 135–42.
Авторы
Р.Мехта, Р.Фицпатрик
Цель портала OmniDoctor – предоставление профессиональной информации врачам, провизорам и фармацевтам.