1. Acerbi D, Brambilla G, Kottakis I. Advances in asthma and COPD management: delivering CFC-free inhaled therapy using Modulite technology. Pulm Pharmacol Ther 2007; 20: 290–303.
2. Allen DB, Mullen M, Mullen B. A meta-analysis of the effect of oral and inhaled corticosteroids on growth. J Allergy Clin Immunol 1994; 93: 967–76.
3. Anderson PJ. Delivery options and devices for aerosolized therapeutics. Chest 2001; 120 (Suppl. 3): 89S–93S.
4. Barnes PJ. Clinical outcome of adding long-acting b-agonists to inhaled corticosteroids. Respir Med 2001; 95 (Suppl. B): S12–6.
5. Barnes PJ. Inhaled glucocorticoids for asthma. N Engl J Med 1995; 332: 868–75.
6. Barnes PJ. Scientific rationale for inhaled combination therapy with long-acting b2-agonists and corticosteroids. Eur Respir J 2002; 19: 182–91.
7. Bateman ED, Boushey HA, Bousquet J et al. Pedersen SE for the GOAL Investigators Group. Can guideline-defined asthma control be achieved? The Gaining Optimal Asthma Control Study. Am J Respir Crit Care Med 2004; 170: 836–44.
8. Becker A, Lemiиre C et al. Summary of recommendations from the Canadian Asthma Consensus guidelines, 2003. CMAJ 2005; 173 (Suppl. 6): S3–11.
9. Bonnet-Gonod F, Kottakis I, Hofman T et al. Beclomethasone dipropionate/ formoterol in a single inhaler improves lung function and clinically meaningful outcomes in moderate to severe asthma (abstract). Eur Respir J 2006; 28 (Suppl. 50): P1230.
10. Boulet LP, Cartier A, Ernst P et al. Safety and efficacy of HFA-134a beclomethasone dipropionate extrafine aerosol over six months. Can Respir J 2004; 11: 123–30.
11. Bousquet J, Dell'Anna C. Modulite technology in the development of formoterol HFApMDI: clinical evidence and future opportunities. Expert Rev Resp Med 2008; 2 (1): 27–36.
12. Carroll N, Cooke C, James A. The distribution of eosinophils and lymphocytes in the large and small airways of asthmatics. Eur Resp J 1997; 10: 292–300.
13. Contoli M, Bousquet J, Fabbri LM et al. The small airways and distal lung compartment in asthma and COPD: a time for reappraisal. Allergy 2009. DOI: 10.1111/j.1398-9995.2009.02242.x
14. Dhillon S, Keating GM. Beclometasone dipropionate/formoterol: in an HFA-propelled pressurised metered-dose inhaler. Drugs 2006; 66: 1475–83.
15. Global Initiative for Asthma. Workshop Report, 2006. http://www.ginasthma.com/download.asp?intId=217
16. Hamid Q. Peripheral inflammation is more important than central inflammation. Respir Med 1997; 91: 11–2.
17. Huchon G et al. Lung function and asthma control with beclomethasone and formoterol in a single inhaler. Respir Med 2008. Doi:10.1016/j.rmed. 2008.09.002
18. Kuyper LM, Pare PD, Hogg JC et al. Characterisation of airways plugging in fatal asthma Am J Med 2003; 115: 6–11.
19. Mak JCW, Nishikawa M, Shirasaki H et al. Protective effects of a glucocorticoid on downregulation of pulmonary b2-adrenergic receptors in vivo. J Clin Invest 1995; 96: 99–106.
20. Mariotti F, Poli G, Acerbi D et al. Lung deposition of BDP/formoterol HFA pMDI in healthy volunteers, asthmatic and COPD patients. Eur Res Congr 2008. Abstract book: Poster P649.
21. Minshall EM, Hogg JC, Hamid QA. Cytokine mRNA expression in asthma is not restricted to the large airways. J Allergy Clin Immunol 1998; 101: 386–90.
22. O’Connor BJ et al. ERS 2009.
23. Papi A, Paggiaro PL, Nicolini G et al. Bеclomethasone/formoterol versus bude-sonide/formoterol combination therapy in asthma. Eur Respir J 2007; 29: 682–9.
24. Papi A, Paggiaro P, Nicolini G et al. Beclomethasone/formoterol vs fluticasone/salmeterol inhaled combinationin moderate to severe asthma. Allergy 2007; 62: 1182–8.
25. Scichilone N, Contino A, Figlioli G et al. Patient perspectives in the management of asthma: improving patient outcomes through critical selection of treatment options. Published online, 2010 February 4.
26. Vos WV, Devolder AD, Debacke LD et al. Long-term effects of combined extrafine beclomethasone (BECL) and formoterol (FORM) treatment in asthma patients. Eur Respir J 2009; 34: S53.
Авторы
Н.П.Княжеская1, А.В.Черняк2
1 Кафедра пульмонологии ФУВ ГБОУ ВПО РНИМУ им. Н.И.Пирогова;
2 НИИ пульмонологии ФМБА России