1. Архипов B.B. Клиническая фармакология рофлумиласта. Пульмонология. 2012; 2: 90–8.
2. Авдеев С.Н. Ингибиторы фосфодиэстеразы-4: новые перспективы противовоспалительной терапии ХОБЛ. Фарматека. 2013; 4: 101–11.
3. Синопальников А.И., Романовских А.Г. Рофлумиласт: новые возможности фармакотерапии ХОБЛ. Рус. мед. журн. 2012; 26: 1339–43.
4. Global Initiative for Chronic Obstructive Lung Disease (GOLD). Global strategy for diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO workshop report. Last updated 2013. www.goldcopd.org/
5. Grootendorst DC, Gauw SA, Verhoosel RM et al. The PDE4 inhibitor roflumilast reduces sputum neutrophil and eosinophil numbers in patients with COPD. Thorax 2007; 62: 1081–7.
6. Rabe KF, Bateman ED, O’Donnell D et al. Roflumilast – an oral anti-inflammatory treatment for chronic obstructive pulmonary disease: a randomized controlled trial. Lancet 2005; 366: 563–71.
7. Calverley PM, Sanchez-Toril F, McIvor A et al. Effect of 1-year treatment with roflumilast in severe chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2007; 176: 154–61.
8. Rennard SI, Calverley PMA, Goehring UM et al. Reduction of exacerbations by the PDE4 inhibitor roflumilast – the importance of defining different subsets of patients with COPD. Respir Research 2011; 12: 18.
9. Bateman ED, Rabe KF, Calverley PMA et al. Roflumilast with long-acting b2-agonists for COPD: influence of exacerbation history. Eur Respir J 2011; 38: 553–60.