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Некоторые аспекты кардиоваскулярной безопасности тиотропия у больных хронической обструктивной болезнью легких и ишемической болезнью сердца
Некоторые аспекты кардиоваскулярной безопасности тиотропия у больных хронической обструктивной болезнью легких и ишемической болезнью сердца
Кароли Н.А., Ребров А.П. Некоторые аспекты кардиоваскулярной безопасности тиотропия у больных хронической обструктивной болезнью легких и ишемической болезнью сердца. Consilium Medicum. 2013; 15 (3): 24–28.
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Полный текст
Список литературы
1. Кароли Н.А., Ребров А.П. Коморбидность у больных хронической обструктивной болезнью легких: место кардиоваскулярной патологии. Рациональная фармакотерапия в кардиологии. 2009; 4: 9–17.
2. Anthonisen NR, Connet JE, Enright PL, Manfreda J. Hospitalizations and mortality in the Lung Health Study. Am J Respir Crit Care Med 2002; 166: 333–9.
3. Sidney S, Sorel M, Quesenberry CP et al. COPD and incident cardiovascular disease hospitalizations and mortality: Kaiser Permanente Medical Care Program. Chest 2005; 128: 2068–75.
4. Jousilahti P, Vartiainen E, Tuomilehto J, Puska P. Symptoms of chronic bronchitis and the risk of coronary disease. Lancet 1996; 348: 567–72.
5. Sin DD, Man SFP. Chronic obstructive pulmonary disease as a risk factor for cardiovascular morbidity and mortality. Proc Am Thorac Soc 2005; 2: 8–11.
6. Peters NL. Snipping the thread of life. Antimuscarinic side effects of medications in the elderly. Arch Int Med 1989; 149: 2414e20.
7. Feinberg M. The problems of anticholinergic adverse effects in older patients. Drugs Aging 1993; 3: 335e48.
8. Worth H, Chung KF, Felser JM et al. Cardio- and cerebrovascular safety of indacaterol vs formoterol, salmeterol, tiotropium and placebo in COPD. Respir Med 2011; 105 (4): 571–9.
9. Lee TA, Simon A, Pickard AS et al. Risk of death associated with medications for recently diagnosed chronic obstructive pulmonary disease. Ann Intern Med 2008; 149: 380–90.
10. Singh S, Loke YK, Furberg CD. Inhaled anticholinergics and risk of major adverse cardiovascular events in patients with chronic obstructive pulmonary disease. J Am Med Assoc 2008; 300: 1439–50.
11. Singh S, Loke YK, Enright P, Furberg CD. Pro-arrhythmic and pro-ischaemic effects of inhaled anticholinergic medications. Thorax 2013; 68 (1): 114–6.
12. Cazzola M, Calzetta L, Matera MG. The cardiovascular risk of tiotropium: is it real? Expert Opin Drug Saf 2010; 9: 783–92.
13. Tashkin DP, Celli B, Senn S et al. A 4-year trial of tiotropium in chronic obstructive pulmonary disease. N Engl J Med 2008; 359: 1543–54.
14. Vogelmeier C, Hederer B, Glaab T et al. Tiotropium versus salmeterol for the prevention of exacerbations of COPD. N Engl J Med 2011; 364 (12): 1093–103.
15. Rodrigo GJ, Castro-Rodriguez JA, Nannini LJ et al. Tiotropium and risk for fatal and nonfatal cardiovascular events in patients with chronic obstructive pulmonary disease: systematic review with meta-analysis. Respir Med 2009; 103 (10): 1421–9.
16. Kesten S, Jara M, Wentworth C, Lanes S et al. Pooled Clinical Trial Analysis of Tiotropium Safety. Chest December 2006; 130: 1695–703.
17. Kesten S, Celli B, Decramer M et al. Tiotropium HandiHaler in the treatment of COPD: a safety review. Int J Chron Obstruct Pulmon Dis 2009; 4: 397–409.
18. Celli B, Decramer M, Leimer I et al. Cardiovascular safety of tiotropium in patients with COPD. Chest 2010; 137 (1): 20–30.
19. Gershon AS, Wang L, To T et al. Survival with tiotropium compared to long-acting Beta-2-agonists in Chronic Obstructive Pulmonary Disease. COPD 2008; 5 (4): 229–34.
20. De Luise C, Lanes SF, Jacobsen J et al. Cardiovascular and respiratory hospitalizations and mortality among users of tiotropium in Denmark. Eur J Epidemiol 2007; 22: 267–72.
21. Verhamme KM, Afonso AS, van Noord C et al. Tiotropium Handihaler and the risk of cardio- or cerebrovascular events and mortality in patients with COPD. Pulm Pharmacol Ther 2012; 25 (1): 19–26.
22. Jara M, Lanes SF, Wentworth C et al. Comparative safety of long-acting inhaled bronchodilators: a cohort study using the UK THIN primary care database. Drug Saf 2007; 30: 1151–60.
23. Short PM, Williamson PA, Elder DH et al. The impact of tiotropium on mortality and exacerbations when added to inhaled corticosteroids and long-acting beta-agonist therapy in COPD. Chest 2012; 141: 81–6.
24. Lee TA, Wilke C, Joo M et al. Outcomes associated with tiotropium use in patients with chronic obstructive pulmonary disease. Arch Intern Med 2009; 169 (15): 1403–10.
25. Jara M, Wentworth C, Lanes S. A new user cohort study comparing the safety of long-acting inhaled bronchodilators in COPD. BMJ Open 2012; 2 (3).
26. FDA (US) (2009) UCM190463. Available at: http://www.fda. gov/ downloads/advisorycommittees/committeesmeetingmaterials/drugs/pulmonary allergydrug sadvisorycommittee/ ucm190463.pdf (accessed 14 October 2011).
27. Santus P, Di Marco F, Radovanovic D, Centanni S. Tiotropium: what came after the UPLIFT study. Expert Opin Pharmacother 2012; 13: 613–8.
28. Singh S, Loke YK, Enrigh PL, Furberg CD. Mortality associated with tiotropium mist inhaler in patients with chronic obstructive pulmonary disease: systematic review and meta-analysis of randomised controlled trials. BMJ 2011; 342: d3215.
29. Dong YH, Lin HH, Shau WY et al. Comparative safety of inhaled medications in patients with chronic obstructive pulmonary disease: systematic review and mixed treatment comparison meta-analysis of randomised controlled trials. Thorax 2013; 68 (1): 48–56.
30. Ichinose M, Fujimoto T, Fukuchi Y. Tiotropium 5 mg via Respimat and 18 mg via HandiHaler; efficacy and safety in Japanese COPD patients. Respir Med 2010; 104: 228–36.
31. http://www.clinicaltrials.gov/ct2/show/NCT01222533? term=205.458&rank=1 (accessed 4 Feb 2013).
32. Metzdorf N, Hallmann C, Disse B. Thorax editorial by Jenkins and Beasley related to tiotropium respimat. Thorax published online February 12, 2013. doi: 10.1136/thoraxjnl-2013-203228.
33. Oba Y, Zaza T, Thameem DM. Safety, tolerability and risk benefit analysis of tiotropium in COPD. Int J Chron Obstruct Pulmon Dis 2008; 3 (4): 575–84. Review.
34. Loke YK, Singh S. Risks Associated With Tiotropium in Chronic Obstructive Pulmonary Disease. Overview of the Evidence to Date. Ther Adv in Drug Safe 2012; 3 (3): 123–31.
35. Lelorier J, Gregoire G, Benhaddad A et al. (1997) Discrepancies between meta-analyses and subsequent large randomized, controlled trials. N Engl J Med 337: 536–42.
36. Horwitz RI, Singer BH, Makuch RW, Viscoli CM. Can treatment that is helpful on average be harmful to some patients? A study of the conflicting information needs of clinical inquiry and drug regulation. J Clin Epidemiol 1996; 49: 395–400.
2. Anthonisen NR, Connet JE, Enright PL, Manfreda J. Hospitalizations and mortality in the Lung Health Study. Am J Respir Crit Care Med 2002; 166: 333–9.
3. Sidney S, Sorel M, Quesenberry CP et al. COPD and incident cardiovascular disease hospitalizations and mortality: Kaiser Permanente Medical Care Program. Chest 2005; 128: 2068–75.
4. Jousilahti P, Vartiainen E, Tuomilehto J, Puska P. Symptoms of chronic bronchitis and the risk of coronary disease. Lancet 1996; 348: 567–72.
5. Sin DD, Man SFP. Chronic obstructive pulmonary disease as a risk factor for cardiovascular morbidity and mortality. Proc Am Thorac Soc 2005; 2: 8–11.
6. Peters NL. Snipping the thread of life. Antimuscarinic side effects of medications in the elderly. Arch Int Med 1989; 149: 2414e20.
7. Feinberg M. The problems of anticholinergic adverse effects in older patients. Drugs Aging 1993; 3: 335e48.
8. Worth H, Chung KF, Felser JM et al. Cardio- and cerebrovascular safety of indacaterol vs formoterol, salmeterol, tiotropium and placebo in COPD. Respir Med 2011; 105 (4): 571–9.
9. Lee TA, Simon A, Pickard AS et al. Risk of death associated with medications for recently diagnosed chronic obstructive pulmonary disease. Ann Intern Med 2008; 149: 380–90.
10. Singh S, Loke YK, Furberg CD. Inhaled anticholinergics and risk of major adverse cardiovascular events in patients with chronic obstructive pulmonary disease. J Am Med Assoc 2008; 300: 1439–50.
11. Singh S, Loke YK, Enright P, Furberg CD. Pro-arrhythmic and pro-ischaemic effects of inhaled anticholinergic medications. Thorax 2013; 68 (1): 114–6.
12. Cazzola M, Calzetta L, Matera MG. The cardiovascular risk of tiotropium: is it real? Expert Opin Drug Saf 2010; 9: 783–92.
13. Tashkin DP, Celli B, Senn S et al. A 4-year trial of tiotropium in chronic obstructive pulmonary disease. N Engl J Med 2008; 359: 1543–54.
14. Vogelmeier C, Hederer B, Glaab T et al. Tiotropium versus salmeterol for the prevention of exacerbations of COPD. N Engl J Med 2011; 364 (12): 1093–103.
15. Rodrigo GJ, Castro-Rodriguez JA, Nannini LJ et al. Tiotropium and risk for fatal and nonfatal cardiovascular events in patients with chronic obstructive pulmonary disease: systematic review with meta-analysis. Respir Med 2009; 103 (10): 1421–9.
16. Kesten S, Jara M, Wentworth C, Lanes S et al. Pooled Clinical Trial Analysis of Tiotropium Safety. Chest December 2006; 130: 1695–703.
17. Kesten S, Celli B, Decramer M et al. Tiotropium HandiHaler in the treatment of COPD: a safety review. Int J Chron Obstruct Pulmon Dis 2009; 4: 397–409.
18. Celli B, Decramer M, Leimer I et al. Cardiovascular safety of tiotropium in patients with COPD. Chest 2010; 137 (1): 20–30.
19. Gershon AS, Wang L, To T et al. Survival with tiotropium compared to long-acting Beta-2-agonists in Chronic Obstructive Pulmonary Disease. COPD 2008; 5 (4): 229–34.
20. De Luise C, Lanes SF, Jacobsen J et al. Cardiovascular and respiratory hospitalizations and mortality among users of tiotropium in Denmark. Eur J Epidemiol 2007; 22: 267–72.
21. Verhamme KM, Afonso AS, van Noord C et al. Tiotropium Handihaler and the risk of cardio- or cerebrovascular events and mortality in patients with COPD. Pulm Pharmacol Ther 2012; 25 (1): 19–26.
22. Jara M, Lanes SF, Wentworth C et al. Comparative safety of long-acting inhaled bronchodilators: a cohort study using the UK THIN primary care database. Drug Saf 2007; 30: 1151–60.
23. Short PM, Williamson PA, Elder DH et al. The impact of tiotropium on mortality and exacerbations when added to inhaled corticosteroids and long-acting beta-agonist therapy in COPD. Chest 2012; 141: 81–6.
24. Lee TA, Wilke C, Joo M et al. Outcomes associated with tiotropium use in patients with chronic obstructive pulmonary disease. Arch Intern Med 2009; 169 (15): 1403–10.
25. Jara M, Wentworth C, Lanes S. A new user cohort study comparing the safety of long-acting inhaled bronchodilators in COPD. BMJ Open 2012; 2 (3).
26. FDA (US) (2009) UCM190463. Available at: http://www.fda. gov/ downloads/advisorycommittees/committeesmeetingmaterials/drugs/pulmonary allergydrug sadvisorycommittee/ ucm190463.pdf (accessed 14 October 2011).
27. Santus P, Di Marco F, Radovanovic D, Centanni S. Tiotropium: what came after the UPLIFT study. Expert Opin Pharmacother 2012; 13: 613–8.
28. Singh S, Loke YK, Enrigh PL, Furberg CD. Mortality associated with tiotropium mist inhaler in patients with chronic obstructive pulmonary disease: systematic review and meta-analysis of randomised controlled trials. BMJ 2011; 342: d3215.
29. Dong YH, Lin HH, Shau WY et al. Comparative safety of inhaled medications in patients with chronic obstructive pulmonary disease: systematic review and mixed treatment comparison meta-analysis of randomised controlled trials. Thorax 2013; 68 (1): 48–56.
30. Ichinose M, Fujimoto T, Fukuchi Y. Tiotropium 5 mg via Respimat and 18 mg via HandiHaler; efficacy and safety in Japanese COPD patients. Respir Med 2010; 104: 228–36.
31. http://www.clinicaltrials.gov/ct2/show/NCT01222533? term=205.458&rank=1 (accessed 4 Feb 2013).
32. Metzdorf N, Hallmann C, Disse B. Thorax editorial by Jenkins and Beasley related to tiotropium respimat. Thorax published online February 12, 2013. doi: 10.1136/thoraxjnl-2013-203228.
33. Oba Y, Zaza T, Thameem DM. Safety, tolerability and risk benefit analysis of tiotropium in COPD. Int J Chron Obstruct Pulmon Dis 2008; 3 (4): 575–84. Review.
34. Loke YK, Singh S. Risks Associated With Tiotropium in Chronic Obstructive Pulmonary Disease. Overview of the Evidence to Date. Ther Adv in Drug Safe 2012; 3 (3): 123–31.
35. Lelorier J, Gregoire G, Benhaddad A et al. (1997) Discrepancies between meta-analyses and subsequent large randomized, controlled trials. N Engl J Med 337: 536–42.
36. Horwitz RI, Singer BH, Makuch RW, Viscoli CM. Can treatment that is helpful on average be harmful to some patients? A study of the conflicting information needs of clinical inquiry and drug regulation. J Clin Epidemiol 1996; 49: 395–400.
Авторы
Н.А.Кароли, А.П.Ребров
Кафедра госпитальной терапии лечебного факультета ГБОУ ВПО Саратовский ГМУ им. В.И.Разумовского Минздрава РФ
Кафедра госпитальной терапии лечебного факультета ГБОУ ВПО Саратовский ГМУ им. В.И.Разумовского Минздрава РФ
Цель портала OmniDoctor – предоставление профессиональной информации врачам, провизорам и фармацевтам.
