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Когнитивные нарушения при поражении мелких церебральных сосудов
Когнитивные нарушения при поражении мелких церебральных сосудов
Дамулин И.В. Когнитивные нарушения при поражении мелких церебральных сосудов. Consilium Medicum. 2014; 16 (9): 10–16.
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Полный текст
Список литературы
1. Greenberg SM. Small vessels, big problems. New Engl J Med 2006; 354 (14): 1451–3.
2. Werring DJ, Coward LJ, Losseff NA et al. Cerebral microbleeds are common in ischemic stroke but rare in TIA. Neurology 2005; 65: 1914–8.
3. Bennett DA, Wilson RS, Gilley DW, Fox JH. Clinical diagnosis of Binswanger’s disease. J Neurol Neurosurg Psychiatry 1990; 53: 961–5.
4. Bousser MG, Tournier-Lasserve E. The story of CADASIL. In: Abstracts of the XVII World Congress of Neurology. London, 2001; p. S5.
5. Guermazi A, Miaux Y, Rovira-Canellas A et al. Neuroradiological findings in vascular dementia. Neuroradiol 2007; 49: 1–22.
6. Vermeer SE, Prins ND, den Heijer T et al. Silent brain infarcts and the risk of dementia and cognitive decline. New Engl J Med 2003; 348: 1215–22.
7. Fein G, Di Sclafani V, Tanabe J et al. Hippocampal and cortical atrophy predict dementia in subcortical ischemic vascular disease. Neurology 2000; 55: 1626–35.
8. Blass JP, Ratan RR. «Silent» strokes and dementia. New Engl J Med 2003; 348 (13): 1277–8.
9. Медведева А.В., Дамулин И.В. Клинические и патогенетические аспекты псевдобульбарного синдрома. Журн. неврологии и психиатрии им. С.С.Корсакова. 2008; 108 (2): 60–5.
10. Maeshima S, Moriwaki H, Ozaki F et al. Silent cerebral infarction and cognitive function in middle-aged neurologically healthy subjects. Acta Neurol Scand 2002; 105: 179–84.
11. van Veluw SJ, Wisse LEM, Kuijf HJ et al. Hippocampal T2 hyperintensities on 7 Tesla MRI. NeuroImage: Clinical 2013; 3: 196–201.
12. deLeeuw FE, van Gijn J. Vascular dementia. Pract Neurol 2003; 3: 86–91.
13. Inzitari M, Pozzi C, Rinaldi LA et al. Cognitive and functional impairment in hypertensive brain microangiopathy. J Neurol Sci 2007; 257: 166–73.
14. Moser DJ, Kanz JE, Garrett KD. White Matter Hyperintensities and Cognition. Ed. by R.Paul et al. Totova: Humana Press Inc., 2005;
p. 223–9.
15. Pantoni L, Poggesi A, Inzitari D. The relation between white-matter lesions and cognition. Curr Opin Neurol 2007; 20: 390–7.
16. Brown WR, Moody DM, Thore CR et al. Vascular dementia in leukoaraiosis may be a consequence of capillary loss not only in the lesions, but in normal-appearing white matter and cortex as well.
J Neurol Sci 2007; 257: 62–6.
17. Jokinen H, Kalska H, Mantyla R et al. Cognitive profile of subcortical ischaemic vascular disease. J Neurol Neurosurg Psychiatry 2006; 77: 28–33.
18. Tomimoto H, Ohtani R, Ihara M. Absence of cholinergic deficits in «pure» vascular dementia. Neurology 2005; 65: 179.
19. Sachdev PS, Wen W, Christensen H, Jorm AF. White matter hyperintensities are related to physical disability and poor motor function. J Neurol Neurosurg Psychiatry 2005; 76: 362–7.
20. Hassan A, Hunt BJ, O’Sullivan M et al. Markers of endothelial dysfunction in lacunar infarction and ischaemicleukoaraiosis. Brain 2003; 126 (2): 424–32.
21. Kovari E, Gold G, Herrmann FR et al. Cortical microinfarcts and demyelination significantly affect cognition in brain aging. Stroke 2004; 35: 410–4.
22. Silbert LC, Nelson C, Howieson DB et al. Impact of white matter hyperintensity volume progression on rate of cognitive and motor decline. Neurology 2008; 71: 108–13.
23. Meyer JS, Xu G, Thornby G et al. Is mild cognitive impairment prodromal for vascular dementia like Alzheimer’s disease? Stroke 2002; 33: 1981–5.
24. Price CC, Jefferson AL, Merino JG et al. Subcortical vascular dementia: Integrating neuropsychological and neuroradiologic data. Neurology 2005; 65: 376–82.
25. Reed BR, Eberling JL, Mungas D et al. Frontal lobe hypometabolism predicts cognitive decline in patients with lacunar infarctions. Arch Neurol 2001; 58: 494–7.
26. Reed BR, Eberling JL, Mungas D et al. Effects of white matter lesions and lacunes on cortical function. Arch Neurol 2004; 61: 1545–50.
27. Mungas D. Contributions of Subcortical Lacunar Infarcts to Cognitive Impairment in Older Persons. In: Vascular Dementia. Cerebrovascular Mechanisms and Clinical Management. Ed. by R.Paul et al. Totova: Humana Press Inc., 2005; p. 211–22.
28. van den Heuvel DMJ, ten Dam VH, de Craen AJM et al. Increase in periventricular white matter hyperintensities parallels decline in mental processing speed in a non-demented elderly population.
J Neurol Neurosurg Psychiatry 2006; 77: 149–53.
29. Bonoczk P, Panczel G, Nagy Z. Vasoreactivity in patients with periventricular white matter lucency. Acta Neurologica Scand 2004; 110 (4): 254–6.
30. Gunstad J, Brickman AM, Paul RH et al. Progressive morphometric and cognitive changes in vascular dementia. Arch Clin Neuropsychol 2005; 20: 229–41.
31. Righart R, Duering M, Gonik M et al. Impact of regional cortical and subcortical changes on processing speed in cerebral small vessel disease. NeuroImage: Clinical 2013; 2: 854–61.
32. Capizzano AA, Schuff N, Amend DL et al. Subcortical ischemic vascular dementia: assessment with quantitative MR imaging and 1H MR spectroscopy. Am J Neuroradiol 2000; 21 (4): 621–30.
33. Vanneste JAL. Three decades of normal pressure hydrocephalus: are we wiser now? J Neurol Neurosurg Psychiatry 1994; 57: 1021–5.
34. Kleinschmidt A, Vuilleumier P. Disconnecting cognition. Curr Opin Neurol 2013; 26 (4): 333–8.
35. Papma JM, den Heijer T, de Koning I et al. The influence of cerebral small vessel disease on default mode network deactivation in mild cognitive impairment. NeuroImage: Clinical 2013; 2: 33–42.
36. Wentzel C, Rockwood K, MacKnight C et al. Progression of impairment in patients with vascular cognitive impairment without dementia. Neurology 2001; 57: 714–6.
37. Ikeda M. Prevention and early intervention for vascular dementia in community dwelling elderly: Findings from the Nakayama study. Psychogeriatrics 2003; 3: 17–20.
38. Kril JJ, Patel S, Harding AJ, Halliday GM. Patients with vascular dementia due to microvascular pathology have significant hippocampal neuronal loss. J Neurol Neurosurg Psychiatry 2002; 72: 747–51.
39. Gainotti G, Acciarri A, Bizzarro A et al. The role of brain infarcts and hippocampal atrophy in subcortical ischaemic vascular dementia. Neurol Sci 2004; 25: 192–7.
40. Benarroch EE. Microglia: Multiple roles in surveillance, circuit shaping, and response to injury. Neurology 2013; 81: 1079–88.
41. Poels MMF, Steyerberg EW, Wieberdink RG et al. Assessment of cerebral small vessel disease predicts individual stroke risk. J Neurol Neurosurg Psychiatry 2012; 83: 1174–9.
42. Elkins JS, O’Meara ES, Longstreth WT et al. Stroke risk factors and loss of high cognitive function. Neurology 2004; 63: 793–9.
43. Imfeld P, Bodmer M, Schuerch M et al. Risk of incident stroke in patients with Alzheimer disease or vascular dementia. Neurology 2013; 81: 910–9.
44. Alagiakrishnan K, McCracken P, Feldman H. Treating vascular risk factors and maintaining vascular health: Is this the way towards successful cognitive ageing and preventing cognitive decline? Postgrad Med J 2006; 82: 101–5.
45. Фонякин А.В., Гераскина Л.А. Роль антитромботической терапии во вторичной профилактике ишемического инсульта у пациентов с сочетанным поражением сосудистых бассейнов. Атмосфера. Нервные болезни. 2010; 1: 2–5.
46. Танашян М.М., Домашенко М.А. Применение курантила при хронических цереброваскулярных заболеваниях. Атмосфера. Нервные болезни. 2005; 3: 8–11.
47. Барышникова Г.А. Применение дипиридамола в общетерапевтической практике. Справ. поликлин. врача. 2007; 14: 11–6.
48. Шмырев В., Васильев А. Современные возможности консервативной первичной и вторичной профилактики ишемического инсульта с применением дезагрегантов. Врач. 2012; 12: 14–7.
49. Muller TH. Inhibition of thrombus formation by low-dose acetylsalicylic acid, dipyridamole, and their combination in a model of platelet-vessel wall interaction. Neurology 2001; 57: S8–11.
50. Gould DB, Phalan FC, van Mil SE et al. Role of COL4A1 in small-vessel disease and hemorrhagic stroke. New Engl J Med 2006; 354 (14): 1489–96.
51. Vahedi K, Boukobza M, Massin P et al. Clinical and brain MRI follow-up study of a family with COL4A1 mutation. Neurology 2007; 69: 1564–8.
2. Werring DJ, Coward LJ, Losseff NA et al. Cerebral microbleeds are common in ischemic stroke but rare in TIA. Neurology 2005; 65: 1914–8.
3. Bennett DA, Wilson RS, Gilley DW, Fox JH. Clinical diagnosis of Binswanger’s disease. J Neurol Neurosurg Psychiatry 1990; 53: 961–5.
4. Bousser MG, Tournier-Lasserve E. The story of CADASIL. In: Abstracts of the XVII World Congress of Neurology. London, 2001; p. S5.
5. Guermazi A, Miaux Y, Rovira-Canellas A et al. Neuroradiological findings in vascular dementia. Neuroradiol 2007; 49: 1–22.
6. Vermeer SE, Prins ND, den Heijer T et al. Silent brain infarcts and the risk of dementia and cognitive decline. New Engl J Med 2003; 348: 1215–22.
7. Fein G, Di Sclafani V, Tanabe J et al. Hippocampal and cortical atrophy predict dementia in subcortical ischemic vascular disease. Neurology 2000; 55: 1626–35.
8. Blass JP, Ratan RR. «Silent» strokes and dementia. New Engl J Med 2003; 348 (13): 1277–8.
9. Медведева А.В., Дамулин И.В. Клинические и патогенетические аспекты псевдобульбарного синдрома. Журн. неврологии и психиатрии им. С.С.Корсакова. 2008; 108 (2): 60–5.
10. Maeshima S, Moriwaki H, Ozaki F et al. Silent cerebral infarction and cognitive function in middle-aged neurologically healthy subjects. Acta Neurol Scand 2002; 105: 179–84.
11. van Veluw SJ, Wisse LEM, Kuijf HJ et al. Hippocampal T2 hyperintensities on 7 Tesla MRI. NeuroImage: Clinical 2013; 3: 196–201.
12. deLeeuw FE, van Gijn J. Vascular dementia. Pract Neurol 2003; 3: 86–91.
13. Inzitari M, Pozzi C, Rinaldi LA et al. Cognitive and functional impairment in hypertensive brain microangiopathy. J Neurol Sci 2007; 257: 166–73.
14. Moser DJ, Kanz JE, Garrett KD. White Matter Hyperintensities and Cognition. Ed. by R.Paul et al. Totova: Humana Press Inc., 2005;
p. 223–9.
15. Pantoni L, Poggesi A, Inzitari D. The relation between white-matter lesions and cognition. Curr Opin Neurol 2007; 20: 390–7.
16. Brown WR, Moody DM, Thore CR et al. Vascular dementia in leukoaraiosis may be a consequence of capillary loss not only in the lesions, but in normal-appearing white matter and cortex as well.
J Neurol Sci 2007; 257: 62–6.
17. Jokinen H, Kalska H, Mantyla R et al. Cognitive profile of subcortical ischaemic vascular disease. J Neurol Neurosurg Psychiatry 2006; 77: 28–33.
18. Tomimoto H, Ohtani R, Ihara M. Absence of cholinergic deficits in «pure» vascular dementia. Neurology 2005; 65: 179.
19. Sachdev PS, Wen W, Christensen H, Jorm AF. White matter hyperintensities are related to physical disability and poor motor function. J Neurol Neurosurg Psychiatry 2005; 76: 362–7.
20. Hassan A, Hunt BJ, O’Sullivan M et al. Markers of endothelial dysfunction in lacunar infarction and ischaemicleukoaraiosis. Brain 2003; 126 (2): 424–32.
21. Kovari E, Gold G, Herrmann FR et al. Cortical microinfarcts and demyelination significantly affect cognition in brain aging. Stroke 2004; 35: 410–4.
22. Silbert LC, Nelson C, Howieson DB et al. Impact of white matter hyperintensity volume progression on rate of cognitive and motor decline. Neurology 2008; 71: 108–13.
23. Meyer JS, Xu G, Thornby G et al. Is mild cognitive impairment prodromal for vascular dementia like Alzheimer’s disease? Stroke 2002; 33: 1981–5.
24. Price CC, Jefferson AL, Merino JG et al. Subcortical vascular dementia: Integrating neuropsychological and neuroradiologic data. Neurology 2005; 65: 376–82.
25. Reed BR, Eberling JL, Mungas D et al. Frontal lobe hypometabolism predicts cognitive decline in patients with lacunar infarctions. Arch Neurol 2001; 58: 494–7.
26. Reed BR, Eberling JL, Mungas D et al. Effects of white matter lesions and lacunes on cortical function. Arch Neurol 2004; 61: 1545–50.
27. Mungas D. Contributions of Subcortical Lacunar Infarcts to Cognitive Impairment in Older Persons. In: Vascular Dementia. Cerebrovascular Mechanisms and Clinical Management. Ed. by R.Paul et al. Totova: Humana Press Inc., 2005; p. 211–22.
28. van den Heuvel DMJ, ten Dam VH, de Craen AJM et al. Increase in periventricular white matter hyperintensities parallels decline in mental processing speed in a non-demented elderly population.
J Neurol Neurosurg Psychiatry 2006; 77: 149–53.
29. Bonoczk P, Panczel G, Nagy Z. Vasoreactivity in patients with periventricular white matter lucency. Acta Neurologica Scand 2004; 110 (4): 254–6.
30. Gunstad J, Brickman AM, Paul RH et al. Progressive morphometric and cognitive changes in vascular dementia. Arch Clin Neuropsychol 2005; 20: 229–41.
31. Righart R, Duering M, Gonik M et al. Impact of regional cortical and subcortical changes on processing speed in cerebral small vessel disease. NeuroImage: Clinical 2013; 2: 854–61.
32. Capizzano AA, Schuff N, Amend DL et al. Subcortical ischemic vascular dementia: assessment with quantitative MR imaging and 1H MR spectroscopy. Am J Neuroradiol 2000; 21 (4): 621–30.
33. Vanneste JAL. Three decades of normal pressure hydrocephalus: are we wiser now? J Neurol Neurosurg Psychiatry 1994; 57: 1021–5.
34. Kleinschmidt A, Vuilleumier P. Disconnecting cognition. Curr Opin Neurol 2013; 26 (4): 333–8.
35. Papma JM, den Heijer T, de Koning I et al. The influence of cerebral small vessel disease on default mode network deactivation in mild cognitive impairment. NeuroImage: Clinical 2013; 2: 33–42.
36. Wentzel C, Rockwood K, MacKnight C et al. Progression of impairment in patients with vascular cognitive impairment without dementia. Neurology 2001; 57: 714–6.
37. Ikeda M. Prevention and early intervention for vascular dementia in community dwelling elderly: Findings from the Nakayama study. Psychogeriatrics 2003; 3: 17–20.
38. Kril JJ, Patel S, Harding AJ, Halliday GM. Patients with vascular dementia due to microvascular pathology have significant hippocampal neuronal loss. J Neurol Neurosurg Psychiatry 2002; 72: 747–51.
39. Gainotti G, Acciarri A, Bizzarro A et al. The role of brain infarcts and hippocampal atrophy in subcortical ischaemic vascular dementia. Neurol Sci 2004; 25: 192–7.
40. Benarroch EE. Microglia: Multiple roles in surveillance, circuit shaping, and response to injury. Neurology 2013; 81: 1079–88.
41. Poels MMF, Steyerberg EW, Wieberdink RG et al. Assessment of cerebral small vessel disease predicts individual stroke risk. J Neurol Neurosurg Psychiatry 2012; 83: 1174–9.
42. Elkins JS, O’Meara ES, Longstreth WT et al. Stroke risk factors and loss of high cognitive function. Neurology 2004; 63: 793–9.
43. Imfeld P, Bodmer M, Schuerch M et al. Risk of incident stroke in patients with Alzheimer disease or vascular dementia. Neurology 2013; 81: 910–9.
44. Alagiakrishnan K, McCracken P, Feldman H. Treating vascular risk factors and maintaining vascular health: Is this the way towards successful cognitive ageing and preventing cognitive decline? Postgrad Med J 2006; 82: 101–5.
45. Фонякин А.В., Гераскина Л.А. Роль антитромботической терапии во вторичной профилактике ишемического инсульта у пациентов с сочетанным поражением сосудистых бассейнов. Атмосфера. Нервные болезни. 2010; 1: 2–5.
46. Танашян М.М., Домашенко М.А. Применение курантила при хронических цереброваскулярных заболеваниях. Атмосфера. Нервные болезни. 2005; 3: 8–11.
47. Барышникова Г.А. Применение дипиридамола в общетерапевтической практике. Справ. поликлин. врача. 2007; 14: 11–6.
48. Шмырев В., Васильев А. Современные возможности консервативной первичной и вторичной профилактики ишемического инсульта с применением дезагрегантов. Врач. 2012; 12: 14–7.
49. Muller TH. Inhibition of thrombus formation by low-dose acetylsalicylic acid, dipyridamole, and their combination in a model of platelet-vessel wall interaction. Neurology 2001; 57: S8–11.
50. Gould DB, Phalan FC, van Mil SE et al. Role of COL4A1 in small-vessel disease and hemorrhagic stroke. New Engl J Med 2006; 354 (14): 1489–96.
51. Vahedi K, Boukobza M, Massin P et al. Clinical and brain MRI follow-up study of a family with COL4A1 mutation. Neurology 2007; 69: 1564–8.
Авторы
И.В.Дамулин
Кафедра нервных болезней и нейрохирургии ГБОУ ВПО Первый МГМУ им. И.М.Сеченова Минздрава России
Кафедра нервных болезней и нейрохирургии ГБОУ ВПО Первый МГМУ им. И.М.Сеченова Минздрава России
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