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Применение фармакопунктуры в комплексной реабилитации больных в раннем восстановительном периоде мозгового инсульта
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Drobyshev V.A., Shpagina L.A., Gudkova E.V. et al. Pharmacopuncture application in a complex rehabilitation of patients in the early recovery period of cerebral stroke. Consilium Medicum. 2017; 19 (2.3. Neurology and Rheumatology): 19–22. DOI: 10.26442/2075-1753_19.2.3.19-22
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Ключевые слова: ишемический инсульт, фармакопунктура, боль, цефалгии, память, внимание, кровообращение, мозг, реабилитация, стимуляция, расстройство.
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The aim of the scientific research was to study during the placebo-controlled trial the severity and speed of relief of cephalgia, parameters of the cerebral hemodynamics and cognitive performance in patients in the early recovery period cerebral stroke. Treated 96 patients (57 women and 39 men) with an average age of 62.4±2.9 years, complaining of headaches impaired concentration and memory, emotional exhaustion, divided into 4 groups: 1st (n=25) received basic medical complex, complemented by pharmacopuncture Cerebrum compositum; 2nd (n=24) – basic package and the pharmacopuncture Placenta compositum; 3rd (n=24) – basic package in combination with pharmacopuncture saline (placebo); in the 4th (n=23) – uses only the basic medical complex. The examination included assessment of: cognitive function on a Mini-Mental State Examination scale (1975), pain by visual analogue scale (1986); ultrasonic duplex scanning of the extracranial divisions of the main arteries of the head of the device, Logic-400 (USA). In the dynamics of therapy in patients in the 1st and 2nd groups showed a more rapid (after 7 minutes) and expressed as (4.5 and 3.8 times by 15-day observation, respectively) reduction in the intensity of cephalgic syndrome than in the 3rd and 4th groups. The best results were identified in patients in the 1st group, where the medical complex was supplemented with pharmacopuncture Cerebrum compositum. Patients of the 1st and 2nd groups revealed an increase in volumetric blood flow rate is 1.3 times, the parameters of resistance index decreased by 1.2 and 1.3 times, respectively, pulsating index is 1.3 times that significantly differed from the same values in the 3rd and 4th groups. The best results in the parameters of cerebral hemocirculation was achieved with the use of pharmacopuncture drug Placenta compositum, whereas positive shifts from the cognitive indicators – Cerebrum compositum. Thus, the inclusion in the complex treatment of patients in the early rehabilitation period of ischemic stroke of pharmacopuncture complex Cerebrum compositum and Placenta compositum causes a rapid and marked reduction in the intensity of cephalgic syndrome, contributes to the correction of parameters of cerebral hemodynamics, has a positive impact on the state of cognitive functions, which increases the effectiveness of treatment.
Key words: ishemic stroke, pharmacopuncture, pain, cephalgia, memory, attention, blood circulation, brain, rehabilitation, stimulation, disorder.
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2. Gusev E.I., Gekht A.B. Vozmozhnosti vtorichnoi profilaktiki insul'ta: znachenie antigipertenzivnoi i antiagregantnoi terapii. Zhurn. nevrologii i psikhiatrii (Pril. Insul't). 2002; 5: 23–30. [in Russian]
3. Batysheva T.T., Parfenov V.A. Reabilitatsiia bol'nykh, perenesshikh insul't v poliklinike vosstanovitel'nogo lecheniia. Lechashchii vrach. 2003; 3: 76–80. [in Russian]
4. Belova A.N., Shepetova O.N. Neiroreabilitatsiia. Rukovodstvo dlia vrachei. M.: Antidor, 2003. [in Russian]
5. Kersshot Ia. Klinicheskoe rukovodstvo po biopunkture. Ispol'zovanie in"ektsii biopreparatov v ezhednevnoi praktike. M.: Arnebiia, 2013. [in Russian]
6. Agasarov L.G. Farmakopunktura (farmakopunkturnaia refleksoterapiia). M.: Arnebiia, 2013. [in Russian]
7. Iakupova A.A. Davletshina R.R., Iakupov R.A. Refleksoterapiia tservikogennoi golovnoi boli. Nevrologicheskii vestn. 2004; 1–2: 97–8. [in Russian]
8. Mar'ianovskii A.A., Rabinovich S.A. Obshchaia terapiia. Katalog preparatov firmy «Biologishe Khail'mittel' Kheel' Gmbkh». M.: Arnebiia, 2015. [in Russian]
9. Dudchenko L.Sh. Gomotoksikologiia i antigomotoksicheskaia terapiia v sovremennoi meditsine. Tavricheskii mediko-biologicheskii vestn. 2005; 8 (2): 100–4. [in Russian]
10. Schneider B, Klein P, Weiser M. Treatment of vertigo with a homeopathic complex remedy compared with usual treatments: a metaanalysis of clinical trials. Arznem-Forsch. Drug Res 2005; 55 (1): 23–9.
11. Folstein MF, Folstein SE, McHugh PR. Mini-mental state. A practical method for grading the cognitive state of patients for the clinician. J Psychiatric Res 1975; 12 (3): 189–98.
1 ФГБОУ ВО «Новосибирский государственный медицинский университет» Минздрава России. 630091, Россия, Новосибирск, Красный пр-т, д. 52;
2 ГБУЗ НСО «Городская клиническая больница №2». 630051, Россия, Новосибирск, ул. Ползунова, д. 21;
3 ФГБОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И.Пирогова» Минздрава России. 117997, Россия, Москва, ул. Островитянова, д. 1
*doctorvik@yandex.ru
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V.A.Drobyshev*1, L.A.Shpagina1, E.V.Gudkova2, D.A.Shashukov2, I.A.Gribacheva1, A.A.Maryanovsky3, E.V.Petrova1
1 Novosibirsk State Medical University of the Ministry of Health of the Russian Federation. 630091, Russian Federation, Novosibirsk, Krasnyi pr-t, d. 52;
2 City Clinical Hospital №2. 630051, Russian Federation, Novosibirsk, ul. Polzunova, d. 21;
3 N.I.Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation. 117997, Russian Federation, Moscow, ul. Ostrovitianova, d. 1
*doctorvik@yandex.ru