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Отдаленные результаты радикальной простатэктомии при местно-распространенном раке предстательной железы
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Lukyanov I.V. Long-term results of radical prostatectomy with locally advanced prostate cancer. Consilium Medicum. 2017; 19 (7): 20–22. DOI: 10.26442/2075-1753_19.7.20-22
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Ключевые слова: рак простаты, радикальная позадилонная простатэктомия, простат-специфический антиген, местно-распространенный рак.
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Radical prostatectomy for locally advanced prostate cancer is not a sufficiently effective method because of the frequent occurrence of early local tumor recurrences and metastases. In this regard, the evaluation of long-term results after radical treatment requires a long period of observation. Radical prostatectomy is limited by age and is performed in patients not older than 70–72 years, expected life expectancy of more than 5–10 years and minimal amount of concomitant diseases in the compensation stage. The level of prostate-specific antigen allows us to identify clinically significant and potentially curable forms of prostate cancer. The study of prognostic factors allowed isolating a group of patients in the stage of T3 with a favorable prognosis for a disease-free lifespan after radical prostatectomy.
Key words: prostate cancer, radical prostatectomy, prostate-specific antigen, locally advanced prostate cancer.
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2. Di Franco S, Sciarra A, Voria G. Role of radical retropubic prostatectomy (RRP) in patients with locally advanced prostate cancer: the influence of Gleason score 8–10. Eur Urol 2001; 39 (Suppl. 5): 536.
3. Quinn M, Babb P. Patterns and trends in prostate cancer incidence, survival, prevalence and mortality. Part I: international comparisons. BJU Int 2002; 90 (2): 162–73.
4. Sostoianie onkologicheskoi pomoshchi naseleniiu Rossii v 2012 godu. Pod red. A.D.Kaprina, V.V.Starinskogo, G.V.Petrovoi. M.: MNIOI im. P.A.Gertsena, 2013; s. 128–31. [in Russian]
5. Djavan B, Remzi M, Zlotta A. Novel artificial neural network for early detection of prostate cancer. J Clin Oncol 2002; 20: 921–29.
6. Hall WH, Jani AB, Ryu JK. The impact of age and comorbidity on survival outcomes and treatment patterns in prostate cancer. Prost Cancer Prost Dis 2005; 8 (1): 22–30.
7. Van den Ouden D, Schroder FH. Management of locally advanced prostate cancer. I. Staging, natural history, and results of radical surgery. World J Urol 2000; 18 (3): 194–203.
ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России. 125993, Россия, Москва, ул. Баррикадная, д. 2/1
i.v.lukianov@mail.ru
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I.V.Lukyanov
Russian Medical Academy of Continuous Professional Education of the Ministry of Health of the Russian Federation. 125993, Russian Federation, Moscow, ul. Barrikadnaia, d. 2/1
i.v.lukianov@mail.ru