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Новости менопаузальной гормональной терапии
Новости менопаузальной гормональной терапии
Демидова Т.Ю., Зенина С.Г., Гасанзаде П.А. Новости менопаузальной гормональной терапии. Consilium Medicum. 2018; 20 (4): 47–51. DOI: 10.26442/2075-1753_2018.4.47-51
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Аннотация
Около 1/3 жизни современной женщины приходится на менопаузу. Менопаузальный переход – это критический период, и крайне важно дать пациенткам полную информацию о возможностях современной гормонотерапии, которая позволяет не только устранить неприятные менопаузальные симптомы и последствия эстрогенного дефицита, но и сохранить социальную активность женщины, улучшить качество ее жизни в целом. В данной статье описан современный взгляд на менопаузальную гормональную терапию с учетом последних актуальных рекомендаций.
Ключевые слова: менопаузальная гормональная терапия, менопауза, эстрогенный дефицит.
Ключевые слова: менопаузальная гормональная терапия, менопауза, эстрогенный дефицит.
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About 1/3 of a modern woman's life falls on menopause. Perimenopausal transition period is a critical period and it is essential to inform patients on possibilities of modern hormone therapy that allows not only to manage unfavorable menopausal symptoms and estrogen deficiency consequences but also to maintain woman's social activity and improve her quality of life. The article presents contemporary view on menopausal hormone therapy based on most recent relevant guidelines.
Key words: menopausal hormone therapy, menopause, estrogen deficiency.
Key words: menopausal hormone therapy, menopause, estrogen deficiency.
Полный текст
Список литературы
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2. Rossouw JE, Anderson GL, Prentice RL et al. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women’s Health Initiative randomized controlled trial. JAMA 2002; 288: 321–33.
3. Rossouw JE, Prentice RL, Manson JE et al. Postmenopausal hormone therapy and risk of cardiovascular disease by age and years since menopause. JAMA 2007; 297: 1465–77.
4. Cobin RH, Goodman NF et al. American Association of Clinical Endocrinologists and American College of Endocrinology Position Statement on menopause-2017 Update. Endocrine Practice 2017; 23 (7): 869–79.2. Rossouw JE, Anderson GL, Prentice RL et al. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women’s Health Initiative randomized controlled trial. JAMA 2002; 288: 321–33.
3. Rossouw JE, Prentice RL, Manson JE et al. Postmenopausal hormone therapy and risk of cardiovascular disease by age and years since menopause. JAMA 2007; 297: 1465–77.
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7. Stuenkel CA, Davis SR, Gompel A et al. Treatment of Symptoms of the Menopause: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab 2015; 100 (11): 3975–4011.
8. Shao H, Breitner JC, Whitmer RA et al. Hormone therapy and Alzheimer disease dementia: new findings from the Cache County Study. Neurology 2012; 79: 1846–52.
9. Manson JE, Chlebowski RT, Stefanick ML et al. Menopausal hormone therapy and health outcomes during the intervention and extended poststopping phases of the Women's Health Initiative randomized trials. JAMA 2013; 310: 1353–68.
10. National Osteoporosis Foundation. 2014 Clinician’s Guide to Prevention and Treatment of Osteoporosis. http://nof.org/files/nof/public/content/file/2791/upload/919.pdf
11. Boardman HM, Hartley L, Eisinga A et al. Hormone therapy for preventing cardiovascular disease in post-menopausal women. Cochrane Database Syst Rev 2015; 3: CD002229.
12. Files JA, Ko MG, Pruthi S. Bioidentical hormone therapy. Mayo Clin Proc 2011; 86: 673–80.
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1. Harlow SD, Gass M, Hall JE et al. Executive summary of the Stages of Reproductive Aging Workshop +10: addressing the unfinished agenda of staging reproductive aging. Climacteric 2012; 15 (2): 105–14.
2. Rossouw JE, Anderson GL, Prentice RL et al. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women’s Health Initiative randomized controlled trial. JAMA 2002; 288: 321–33.
3. Rossouw JE, Prentice RL, Manson JE et al. Postmenopausal hormone therapy and risk of cardiovascular disease by age and years since menopause. JAMA 2007; 297: 1465–77.
4. Cobin RH, Goodman NF et al. American Association of Clinical Endocrinologists and American College of Endocrinology Position Statement on menopause-2017 Update. Endocrine Practice 2017; 23 (7): 869–79.
5. Santen RJ, Allred DC, Ardoin SP et al. Postmenopausal hormone therapy: an Endocrine Society scientific statement. J Clin Endocrinol Metab 2010; 95: s1–s66.
6. Maclennan AH, Broadbent JL, Lester S, Moore V. Oral oestrogen and combined oestrogen/progestogen therapy versus placebo for hot flushes. Cochrane Database Syst Rev 2004; 4: CD002978.
7. Stuenkel CA, Davis SR, Gompel A et al. Treatment of Symptoms of the Menopause: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab 2015; 100 (11): 3975–4011.
8. Shao H, Breitner JC, Whitmer RA et al. Hormone therapy and Alzheimer disease dementia: new findings from the Cache County Study. Neurology 2012; 79: 1846–52.
9. Manson JE, Chlebowski RT, Stefanick ML et al. Menopausal hormone therapy and health outcomes during the intervention and extended poststopping phases of the Women's Health Initiative randomized trials. JAMA 2013; 310: 1353–68.
10. National Osteoporosis Foundation. 2014 Clinician’s Guide to Prevention and Treatment of Osteoporosis. http://nof.org/files/nof/public/content/file/2791/upload/919.pdf
11. Boardman HM, Hartley L, Eisinga A et al. Hormone therapy for preventing cardiovascular disease in post-menopausal women. Cochrane Database Syst Rev 2015; 3: CD002229.
12. Files JA, Ko MG, Pruthi S. Bioidentical hormone therapy. Mayo Clin Proc 2011; 86: 673–80.
2. Rossouw JE, Anderson GL, Prentice RL et al. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women’s Health Initiative randomized controlled trial. JAMA 2002; 288: 321–33.
3. Rossouw JE, Prentice RL, Manson JE et al. Postmenopausal hormone therapy and risk of cardiovascular disease by age and years since menopause. JAMA 2007; 297: 1465–77.
4. Cobin RH, Goodman NF et al. American Association of Clinical Endocrinologists and American College of Endocrinology Position Statement on menopause-2017 Update. Endocrine Practice 2017; 23 (7): 869–79.
5. Santen RJ, Allred DC, Ardoin SP et al. Postmenopausal hormone therapy: an Endocrine Society scientific statement. J Clin Endocrinol Metab 2010; 95: s1–s66.
6. Maclennan AH, Broadbent JL, Lester S, Moore V. Oral oestrogen and combined oestrogen/progestogen therapy versus placebo for hot flushes. Cochrane Database Syst Rev 2004; 4: CD002978.
7. Stuenkel CA, Davis SR, Gompel A et al. Treatment of Symptoms of the Menopause: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab 2015; 100 (11): 3975–4011.
8. Shao H, Breitner JC, Whitmer RA et al. Hormone therapy and Alzheimer disease dementia: new findings from the Cache County Study. Neurology 2012; 79: 1846–52.
9. Manson JE, Chlebowski RT, Stefanick ML et al. Menopausal hormone therapy and health outcomes during the intervention and extended poststopping phases of the Women's Health Initiative randomized trials. JAMA 2013; 310: 1353–68.
10. National Osteoporosis Foundation. 2014 Clinician’s Guide to Prevention and Treatment of Osteoporosis. http://nof.org/files/nof/public/content/file/2791/upload/919.pdf
11. Boardman HM, Hartley L, Eisinga A et al. Hormone therapy for preventing cardiovascular disease in post-menopausal women. Cochrane Database Syst Rev 2015; 3: CD002229.
12. Files JA, Ko MG, Pruthi S. Bioidentical hormone therapy. Mayo Clin Proc 2011; 86: 673–80.
Авторы
Т.Ю.Демидова*1, С.Г.Зенина2, П.А.Гасанзаде2
1 ФГБОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И.Пирогова» Минздрава России. 117997, Россия, Москва, ул. Островитянова, д. 1;
2 ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России. 123995, Россия, Москва, ул. Баррикадная, д. 2/;
*t.y.demidova@gmail.com
1 ФГБОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И.Пирогова» Минздрава России. 117997, Россия, Москва, ул. Островитянова, д. 1;
2 ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России. 123995, Россия, Москва, ул. Баррикадная, д. 2/;
*t.y.demidova@gmail.com
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T.Yu.Demidova*1, S.G.Zenina2, P.A.Gasanzade2
1 N.I.Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation. 117997, Russian Federation, Moscow, ul. Ostrovitianova, d. 1;
2 Russian Medical Academy of Continuous Professional Education of the Ministry of Health of the Russian Federation. 123995, Russian Federation, Moscow, ul. Barrikadnaia, d. 2/1
*t.y.demidova@gmail.com
1 N.I.Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation. 117997, Russian Federation, Moscow, ul. Ostrovitianova, d. 1;
2 Russian Medical Academy of Continuous Professional Education of the Ministry of Health of the Russian Federation. 123995, Russian Federation, Moscow, ul. Barrikadnaia, d. 2/1
*t.y.demidova@gmail.com
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