В статье приведены актуальные классификации физиологических и патологических выделений из половых путей, представлена таблица-опросник для уточнения возможных факторов, спровоцировавших появление жалоб. Согласно международным протоколам и российским рекомендациям изложены методы диагностики и терапии урогенитального хламидиоза, трихомониаза, бактериального вагиноза и кандидозной инфекции.
The article presents modern classifications of physiological and pathological vaginal discharge as well as a questionnaire table for clarification of various factors that resulted in symptoms onset. Diagnostic and treatment methods for urogenital chlamydiosis, trichomoniasis, bacterial vaginosis, and candida infections are presented according to international protocols and Russian guidelines.
1. Rodrigues MM, Fernandes PA, Haddad JP et al. Frequency of Chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma genitalium, Mycoplasma hominis and Ureaplasma species in cervical samples. J Obstet Gynaecol 2011; 31: 237.
2. Workowski KA, Bolan GA; Centers for Disease Control and Prevention. Sexually transmitted diseases treatment guidelines, 2015. MMWR Recomm Rep 2015; 64: 1.
3. Jensen JS, Cusini M, Gomberg M, Moi H. 2016 European guideline on Mycoplasma genitalium infections. J Eur Acad Dermatol Venereol 2016; 30: 1650.
4. Van Schalkwyk J, Yudin MH; Infectious Disease Committee. Vulvovaginitis: screening for and management of trichomoniasis, vulvovaginal candidiasis, and bacterial vaginosis. J Obstet Gynaecol Can 2015; 37: 266.
5. Powell AM, Nyirjesy P. Recurrent vulvovaginitis. Best Pract Res Clin Obstet Gynaecol 2014; 28: 967.
6. Gaydos CA, Beqaj S, Schwebke JR et al. Clinical Validation of a Test for the Diagnosis of Vaginitis. Obstet Gynecol 2017; 130: 181.
7. Bornstein J, Bogliatto F, Haefner HK et al. The 2015 International Society for the Study of Vulvovaginal Disease (ISSVD) Terminology of Vulvar Squamous Intraepithelial Lesions. J Low Genit Tract Dis 2016; 20: 11.
8. Sherrard J, Wilson J, Donders G, Mendling W. 2018 European (IUSTI/WHO) International Union against sexually transmitted infections (IUSTI) World Health Organisation (WHO) guideline on the management of vaginal discharge. Int J STD AIDS 2018; 29 (13): 1258–72. DOI: 10.1177/0956462418785451
9. Schwebke JR, Muzny CA, Josey WE. Role of Gardnerella vaginalis in the pathogenesis of Bacterial Vaginosis: A Conceptual Model. J Infect Dis 2014; 10: 338–43.
10. Mason MJ, Winter AJ. How to diagnose and treat aerobic and desquamative inflammatory vaginitis. Sex Transm Infect 2017; 93: 8–10.
11. Balkus JE, Manhart LE, Lee J et al. Periodic presumptive treatment for vaginal infections may reduce the incidence of sexually transmitted bacterial infections. J Infect Dis 2016; 213: 1932–7.
12. Holzer I, Farr A, Hagmann M, Petricevic L. The colonization with Candida species is more harmful in the second trimester of pregnancy. Arch Gynecol Obstet 2017; 295: 891–5.
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1. Rodrigues MM, Fernandes PA, Haddad JP et al. Frequency of Chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma genitalium, Mycoplasma hominis and Ureaplasma species in cervical samples. J Obstet Gynaecol 2011; 31: 237.
2. Workowski KA, Bolan GA; Centers for Disease Control and Prevention. Sexually transmitted diseases treatment guidelines, 2015. MMWR Recomm Rep 2015; 64: 1.
3. Jensen JS, Cusini M, Gomberg M, Moi H. 2016 European guideline on Mycoplasma genitalium infections. J Eur Acad Dermatol Venereol 2016; 30: 1650.
4. Van Schalkwyk J, Yudin MH; Infectious Disease Committee. Vulvovaginitis: screening for and management of trichomoniasis, vulvovaginal candidiasis, and bacterial vaginosis. J Obstet Gynaecol Can 2015; 37: 266.
5. Powell AM, Nyirjesy P. Recurrent vulvovaginitis. Best Pract Res Clin Obstet Gynaecol 2014; 28: 967.
6. Gaydos CA, Beqaj S, Schwebke JR et al. Clinical Validation of a Test for the Diagnosis of Vaginitis. Obstet Gynecol 2017; 130: 181.
7. Bornstein J, Bogliatto F, Haefner HK et al. The 2015 International Society for the Study of Vulvovaginal Disease (ISSVD) Terminology of Vulvar Squamous Intraepithelial Lesions. J Low Genit Tract Dis 2016; 20: 11.
8. Sherrard J, Wilson J, Donders G, Mendling W. 2018 European (IUSTI/WHO) International Union against sexually transmitted infections (IUSTI) World Health Organisation (WHO) guideline on the management of vaginal discharge. Int J STD AIDS 2018; 29 (13): 1258–72. DOI: 10.1177/0956462418785451
9. Schwebke JR, Muzny CA, Josey WE. Role of Gardnerella vaginalis in the pathogenesis of Bacterial Vaginosis: A Conceptual Model. J Infect Dis 2014; 10: 338–43.
10. Mason MJ, Winter AJ. How to diagnose and treat aerobic and desquamative inflammatory vaginitis. Sex Transm Infect 2017; 93: 8–10.
11. Balkus JE, Manhart LE, Lee J et al. Periodic presumptive treatment for vaginal infections may reduce the incidence of sexually transmitted bacterial infections. J Infect Dis 2016; 213: 1932–7.
12. Holzer I, Farr A, Hagmann M, Petricevic L. The colonization with Candida species is more harmful in the second trimester of pregnancy. Arch Gynecol Obstet 2017; 295: 891–5.
Авторы
Е.И. Боровкова
ФГБОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России, Москва, Россия katyanikitina@mail.ru
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Ekaterina I. Borovkova
Pirogov Russian National Research Medical University, Moscow, Russia katyanikitina@mail.ru