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Синдром Лезера–Трела при раке ободочной кишки: собственное наблюдение
DOI: 10.26442/20751753.2020.8.200026
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Balutsky V.V., Vinogradov I.A. Leser–Trélat sign in patients with colon cancer: clinical case. Consilium Medicum. 2020; 22 (8): 90–92. DOI: 10.26442/20751753.2020.8.200026
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Ключевые слова: синдром Лезера–Трела, рак ободочной кишки.
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Leser–Trélat sign that manifests as eruption of multiple seborrheic keratoses is a rare but valuable for diagnostics paraneoplastic syndrome. We present a clinical case of Leser–Trélat sign in a patient with colon cancer. Our opinion s that all patients with sudden onset and rapid progression of seborrheic keratoses should be included in diagnostic screening for undetected malignant process.
Key words: Leser–Trélat sign, colon cancer.
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1. Khidchenko S.V., Apanasovich V.G., Chizh K.A. Paraneoplastic syndromes. Teaching aid. Minsk: BSMU, 2018 (in Russian).
2. Rusak Iu.E., Efanova E.N., Pavlova E.V. et al. Sindrom Lezera–Trela u bol'noi melanomoi. Klin. dermatologiia i venerologiia. 2017; 4: 26–30 (in Russian).
3. Olisova O.Iu., Tepliuk N.P., Grabovskaia O.V. et al. Keratodermii kak paraneoplasticheskii sindrom. Rus. med. zhurn. 2016; 10: 654–6 (in Russian).
4. Chakradeo K, Narsinghpura K, Ekladious A. Sign of Leser–Trélat. BMJ Case Rep Published online 2016. DOI: 10.1136/bcr-2016-215316
5. Wu GY, Selsky N, Grant-Kels JM. Atlas of dermatological manifestation of gastrointestinal disease. Springer 2013; p. 79–80.
6. Ponti G, Luppi G, Losi L. Leser–Trélat syndrome in patients affected by six multiple metachronous primitive cancers. J Hematol Oncol 2010; 3: 2. DOI: 10.1186/1756-8722-3-2
7. Gevorkov A.R., Dar'ialova S.L. Paraneoplasticheskie sindromy (obzor). Klin. gerontologiia. 2009; 2: 34–49 (in Russian).
8. Leser E. Ueber ein die Krebskrankheit beim Menschen haufig begleitendes, noch wenig gekanntes Symptom. Munchener Med Wochenschr 1901; 51: 2035–6.
9. Salavastru CM, Constantin MM, Mateescu B, Tiplica GS. Syndrome of Leser–Trélat: a case presentation. Dermatol Venerol (Buc); 52: 89–91.
10. Gupta SK, Mishra A, Arora AK. Sign of Leser–Trélat: An association with benign swellings. J Pakistan Assoc Dermatol 2014; 24 (1): 83–5.
11. Husain Z, Ho JK, Hantash BM. Sign and pseudo-sign of Leser–Trélat: case reports and a review of the literature J Drugs Dermatol 2013; 12 (5): 79–87.
12. Turan E, Yesilova Y, Yurt N, Koçarslan S. Leser–Trélat Sign: Does It Really Exist? Acta Dermatovenerol Croat 2013; 21 (2): 128–30.
13. The status of cancer care for the population of Russia in 2017. Ed. A.D.Caprina, V.V.Starinsky, G.V.Petrova. Moscow: Herzen MNIOI, 2018 (in Russian).
14. Tanaka T. Colorectal carcinogenesis: review of human and experimental animal studies. J Carcinog 2009; 8: 5. DOI: 10.4103/1477-3163.49014
ФГКУ «1586 Военный клинический госпиталь» Минобороны России, Подольск, Россия
*viktor-baluckij@yandex.ru
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Viktor V. Balutsky*, Ilya A. Vinogradov
Federal 1586 Military Clinical Hospital, Podolsk, Russia
*viktor-baluckij@yandex.ru