1. Update to CDC's sexually transmitted diseases treatment guidelines, 2006: fluoroquinolones no longer recommended for treatment of gonococcal infections. MMWR Morb Mortal Wkly Rep 2007; 56 (14): 332–6.
2. Availability of cefixime 400 mg tablets--United States, April 2008. MMWR Morb Mortal Wkly Rep 2008; 57 (16): 435.
3. Fine D, Dicker L, Mosure D, Berman S. Increasing chlamydia positivity in women screened in family planning clinics: do we know why? Sex Transm Dis Jan 2008; 35 (1): 47–52.
4. Greene JP, Stafford E. Prevalence of Chlamydia trachomatis among active duty male soldiers reporting to a troop medical clinic for routine health care. South Med J May 2007; 100 (5): 478–81.
5. Franceschi S, Smith JS, van den Brule A et al. Cervical infection with Chlamydia trachomatis and Neisseria gonorrhoeae in women from ten areas in four continents. A cross-sectional study. Sex Transm Dis 2007; 34 (8): 563–9.
6. Yu MC, Li LH, Tang LH, Chen KT. Genital chlamydial infection among male attendees at a sexually transmitted disease clinic in urban Taiwan. Public Health 2007; 121 (7): 534–9.
7. Somani J, Bhullar VB, Workowski KA et al. Multiple drug-resistant Chlamydia trachomatis associated with clinical treatment failure. J Infect Dis 2000; 181 (4): 1421–7.
8. Workowski KA, Berman SM. Sexually transmitted diseases treatment guidelines, 2006. MMWR Recomm Rep 2006; 55 (RR-11): 1–94.
9. Radcliffe KW. Introduction. European STD guidelines. Int J STD AIDS 2001; 12 (Suppl. 3): 2–3.
10. WHO. Guidelines for the management of sexually transmitted infections. Geneva: World Health Organization; 2003.
11. Association for Genitourinary Medicine (AGUM) MSftSoVDM. 2002 national guideline on the management of non-gonococcal urethritis.: London: Association for Genitourinary Medicine (AGUM), Medical Society for the Study of Venereal Disease (MSSVD). 2002.
12. Lau CY, Qureshi AK. Azithromycin versus doxycycline for genital chlamydial infections: a meta-analysis of randomized clinical trials. Sex Transm Dis 2002; 29 (9): 497–502.
13. Geisler WM. Management of uncomplicated Chlamydia trachomatis infections in adolescents and adults: evidence reviewed for the 2006 Centers for Disease Control and Prevention sexually transmitted diseases treatment guidelines. Clin Infect Dis 2007; 44 (Suppl. 3): S77–83.
14. Higgins J, Green S, eds. Cochrane Handbook for Systematic Reviews of Interventions Version 5.0.0 [updated February 2008]. The Cochrane Collaboration, 2008. Chichester, UK: John Wiley & Sons, Ltd.; 2006.
15. Steingrimsson O, Olafsson JH, Thorarinsson H et al. Azithromycin in the treatment of sexually transmitted disease. J Antimicrob Chemother 1990; 25 (Suppl. A): 109–14.
16. Whatley JD, Thin RN, Mumtaz G, Ridgway GL. Azithromycin vs doxycycline in the treatment of non-gonococcal urethritis. Int J STD AIDS 1991; 2 (4): 248–51.
17. Martin DH, Mroczkowski TF, Dalu ZA et al. A controlled trial of a single dose of azithromycin for the treatment of chlamydial urethritis and cervicitis. The Azithromycin for Chlamydial Infections Study Group. N Engl J Med 1992; 327 (13): 921–5.
18. Nilsen A, Halsos A, Johansen A et al. A double blind study of single dose azithromycin and doxycycline in the treatment of chlamydial urethritis in males. Genitourin Med 1992; 68 (5): 325–7.
19. Lister PJ, Balechandran T, Ridgway GL, Robinson AJ. Comparison of azithromycin and doxycycline in the treatment of non-gonococcal urethritis in men. (Suppl. E) 1993; 31.
20. Lauharanta J, Saarinen K, Mustonen MT, Happonen HP. Single-dose oral azithromycin versus seven-day doxycycline in the treatment of non-gonococcal urethritis in males. J Antimicrob Chemother 1993; 31 (Suppl. E): 177–83.
21. Steingrimsson O, Olafsson JH, Thorarinsson H et al. Single dose azithromycin treatment of gonorrhea and infections caused by C. trachomatis and U. urealyticum in men. Sex Transm Dis 1994; 21 (1): 43–6.
22. Stamm WE, Hicks CB, Martin DH et al. Azithromycin for empirical treatment of the nongonococcal urethritis syndrome in men. A randomized double-blind study. Jama 1995; 274 (7): 545–9.
23. Jaspersen D. Drug Safety 2000; 22 (3): 237–49.
24. Bradshaw CS, Jensen JS, Tabrizi SN et al. Azithromycin failure in Mycoplasma genitalium urethritis. Emerg Infect Dis 2006; 12 (7): 1149–52.
25. Ross JD, Jensen JS. Mycoplasma genitalium as a sexually transmitted infection: implications for screening, testing, and treatment. Sex Transm Infect 2006; 82 (4): 269–71.

________________________________________________

1. Update to CDC's sexually transmitted diseases treatment guidelines, 2006: fluoroquinolones no longer recommended for treatment of gonococcal infections. MMWR Morb Mortal Wkly Rep 2007; 56 (14): 332–6.
2. Availability of cefixime 400 mg tablets--United States, April 2008. MMWR Morb Mortal Wkly Rep 2008; 57 (16): 435.
3. Fine D, Dicker L, Mosure D, Berman S. Increasing chlamydia positivity in women screened in family planning clinics: do we know why? Sex Transm Dis Jan 2008; 35 (1): 47–52.
4. Greene JP, Stafford E. Prevalence of Chlamydia trachomatis among active duty male soldiers reporting to a troop medical clinic for routine health care. South Med J May 2007; 100 (5): 478–81.
5. Franceschi S, Smith JS, van den Brule A et al. Cervical infection with Chlamydia trachomatis and Neisseria gonorrhoeae in women from ten areas in four continents. A cross-sectional study. Sex Transm Dis 2007; 34 (8): 563–9.
6. Yu MC, Li LH, Tang LH, Chen KT. Genital chlamydial infection among male attendees at a sexually transmitted disease clinic in urban Taiwan. Public Health 2007; 121 (7): 534–9.
7. Somani J, Bhullar VB, Workowski KA et al. Multiple drug-resistant Chlamydia trachomatis associated with clinical treatment failure. J Infect Dis 2000; 181 (4): 1421–7.
8. Workowski KA, Berman SM. Sexually transmitted diseases treatment guidelines, 2006. MMWR Recomm Rep 2006; 55 (RR-11): 1–94.
9. Radcliffe KW. Introduction. European STD guidelines. Int J STD AIDS 2001; 12 (Suppl. 3): 2–3.
10. WHO. Guidelines for the management of sexually transmitted infections. Geneva: World Health Organization; 2003.
11. Association for Genitourinary Medicine (AGUM) MSftSoVDM. 2002 national guideline on the management of non-gonococcal urethritis.: London: Association for Genitourinary Medicine (AGUM), Medical Society for the Study of Venereal Disease (MSSVD). 2002.
12. Lau CY, Qureshi AK. Azithromycin versus doxycycline for genital chlamydial infections: a meta-analysis of randomized clinical trials. Sex Transm Dis 2002; 29 (9): 497–502.
13. Geisler WM. Management of uncomplicated Chlamydia trachomatis infections in adolescents and adults: evidence reviewed for the 2006 Centers for Disease Control and Prevention sexually transmitted diseases treatment guidelines. Clin Infect Dis 2007; 44 (Suppl. 3): S77–83.
14. Higgins J, Green S, eds. Cochrane Handbook for Systematic Reviews of Interventions Version 5.0.0 [updated February 2008]. The Cochrane Collaboration, 2008. Chichester, UK: John Wiley & Sons, Ltd.; 2006.
15. Steingrimsson O, Olafsson JH, Thorarinsson H et al. Azithromycin in the treatment of sexually transmitted disease. J Antimicrob Chemother 1990; 25 (Suppl. A): 109–14.
16. Whatley JD, Thin RN, Mumtaz G, Ridgway GL. Azithromycin vs doxycycline in the treatment of non-gonococcal urethritis. Int J STD AIDS 1991; 2 (4): 248–51.
17. Martin DH, Mroczkowski TF, Dalu ZA et al. A controlled trial of a single dose of azithromycin for the treatment of chlamydial urethritis and cervicitis. The Azithromycin for Chlamydial Infections Study Group. N Engl J Med 1992; 327 (13): 921–5.
18. Nilsen A, Halsos A, Johansen A et al. A double blind study of single dose azithromycin and doxycycline in the treatment of chlamydial urethritis in males. Genitourin Med 1992; 68 (5): 325–7.
19. Lister PJ, Balechandran T, Ridgway GL, Robinson AJ. Comparison of azithromycin and doxycycline in the treatment of non-gonococcal urethritis in men. (Suppl. E) 1993; 31.
20. Lauharanta J, Saarinen K, Mustonen MT, Happonen HP. Single-dose oral azithromycin versus seven-day doxycycline in the treatment of non-gonococcal urethritis in males. J Antimicrob Chemother 1993; 31 (Suppl. E): 177–83.
21. Steingrimsson O, Olafsson JH, Thorarinsson H et al. Single dose azithromycin treatment of gonorrhea and infections caused by C. trachomatis and U. urealyticum in men. Sex Transm Dis 1994; 21 (1): 43–6.
22. Stamm WE, Hicks CB, Martin DH et al. Azithromycin for empirical treatment of the nongonococcal urethritis syndrome in men. A randomized double-blind study. Jama 1995; 274 (7): 545–9.
23. Jaspersen D. Drug Safety 2000; 22 (3): 237–49.
24. Bradshaw CS, Jensen JS, Tabrizi SN et al. Azithromycin failure in Mycoplasma genitalium urethritis. Emerg Infect Dis 2006; 12 (7): 1149–52.
25. Ross JD, Jensen JS. Mycoplasma genitalium as a sexually transmitted infection: implications for screening, testing, and treatment. Sex Transm Infect 2006; 82 (4): 269–71.

К.Л.Локшин1, В.В.Рафальский2, С.В.Королев2

1. Урологическая клиника им. Р.М.Фронштейна, Московская медицинская академия им. И.М.Сеченова,
2. ГОУ ВПО Смоленская государственная медицинская академия Росздрава