Поливитаминные препараты и нутриенты: роль в восполнении дефицита фолиевой кислоты и йода у беременных

1. McCormick DB. Vitamin/mineral supplements: of questionable benefit for the general population. Nutr Rev 2010; 68 (4): 207–13.
2. Wagner C. Biochemical role of folate in cellular metabolism. New York, NY: M.Dekker. 1995; p. 23–42.
3. Nijhout H et al. Long-range allosteric interactions berween the folate and methionine cycles stabilize DNA methylation reaction rate. Epigenetics 2006; 1: 81–97.
4. Stanger O et al. Homocysteine, folate and vitamin В12 in neuropsychiatric diseases (review and treatment recommendations). Expert Rev Neurother 2009; 9 (9): 1393–412.
5. Gilbody S, Lewis S. Methylenetetrahydrofolate reductese (MTHFR) genetic polymorphisms and psychiatric disorders (a HuGE review). Am J Epidemiol 2007; 165: 1–13.
6. Giovannucci E. Epidemiologic studies of folate and colorectal neoplasia: a rewiew. J Nutr 2002; 132 (suppl.): 2350S–5.
7. Lee НС et al. Association study of four polymorphisms in three folate-rlated enzyme genes with non-obstructive male infertility. Hum Reprod 2006; 21: 3162–70.
8. Czeizei AE. Maternal use use of nutritional supplements during the first month of pregnancy and decreased risk of Down’s syndrome: case-control study. A.E.Czeizei, E.Puho. Nutrition 2005; 21: 698–704.
9. Patterson D. Folate metabolism and the risk of Down syndrome. D.Patterson. Down Syndr Res Pract 2008; 12 (2): 93–7.
10. Salerno P et al. Folic acid and congenital malformation: scientific evidence and public health strategies. Ann Ig 2008; 20 (6): 519–30.
11. Заболевания щитовидной железы во время беременности. Диагностика, лечение, профилактика: пособие для врачей. Под ред. Г.А.Мельниченко, В.В.Фадеева, И.И.Дедова. М.: Мед ЭкспертПресс, 2003.
12. Zimmermann MB. Iodine deficiency in pregnancy and the effects of maternal iodine supplementation on the offspring: a review. Am J Clin Nutr 2009; 89 (2): 668S–672.
13. Melse-Boonstra A, Jaiswal N. Iodine deficiency in pregnancy, infancy and childhood and its consequences for brain development. Best Pract Res Clin Endocrinol Metab 2010; 24 (1): 29–38.
14. Perez-Lopez FR. Iodine and thyroid hormones during pregnancy and postpartum. Gyn Endocrinol 2007; 23 (7): 414–28.
15. Нормы физиологических потребностей в энергии и пищевых веществах для различных групп населения Российской Федерации МР 2.3.1.2432-08.
16. Otten JJ et al. Institute of Medicine. Dietary Reference Intakes: the essential guide to nutrient requirements. The National Academies Press, 2006.
17. Becker DV et al. Iodine supplementation for pregnancy and lactation – Unated States and Canada: recomendatons of the American Thyroid Association. Thyroid 2006; 16: 949–51.

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1. McCormick DB. Vitamin/mineral supplements: of questionable benefit for the general population. Nutr Rev 2010; 68 (4): 207–13.
2. Wagner C. Biochemical role of folate in cellular metabolism. New York, NY: M.Dekker. 1995; p. 23–42.
3. Nijhout H et al. Long-range allosteric interactions berween the folate and methionine cycles stabilize DNA methylation reaction rate. Epigenetics 2006; 1: 81–97.
4. Stanger O et al. Homocysteine, folate and vitamin В12 in neuropsychiatric diseases (review and treatment recommendations). Expert Rev Neurother 2009; 9 (9): 1393–412.
5. Gilbody S, Lewis S. Methylenetetrahydrofolate reductese (MTHFR) genetic polymorphisms and psychiatric disorders (a HuGE review). Am J Epidemiol 2007; 165: 1–13.
6. Giovannucci E. Epidemiologic studies of folate and colorectal neoplasia: a rewiew. J Nutr 2002; 132 (suppl.): 2350S–5.
7. Lee НС et al. Association study of four polymorphisms in three folate-rlated enzyme genes with non-obstructive male infertility. Hum Reprod 2006; 21: 3162–70.
8. Czeizei AE. Maternal use use of nutritional supplements during the first month of pregnancy and decreased risk of Down’s syndrome: case-control study. A.E.Czeizei, E.Puho. Nutrition 2005; 21: 698–704.
9. Patterson D. Folate metabolism and the risk of Down syndrome. D.Patterson. Down Syndr Res Pract 2008; 12 (2): 93–7.
10. Salerno P et al. Folic acid and congenital malformation: scientific evidence and public health strategies. Ann Ig 2008; 20 (6): 519–30.
11. Заболевания щитовидной железы во время беременности. Диагностика, лечение, профилактика: пособие для врачей. Под ред. Г.А.Мельниченко, В.В.Фадеева, И.И.Дедова. М.: Мед ЭкспертПресс, 2003.
12. Zimmermann MB. Iodine deficiency in pregnancy and the effects of maternal iodine supplementation on the offspring: a review. Am J Clin Nutr 2009; 89 (2): 668S–672.
13. Melse-Boonstra A, Jaiswal N. Iodine deficiency in pregnancy, infancy and childhood and its consequences for brain development. Best Pract Res Clin Endocrinol Metab 2010; 24 (1): 29–38.
14. Perez-Lopez FR. Iodine and thyroid hormones during pregnancy and postpartum. Gyn Endocrinol 2007; 23 (7): 414–28.
15. Нормы физиологических потребностей в энергии и пищевых веществах для различных групп населения Российской Федерации МР 2.3.1.2432-08.
16. Otten JJ et al. Institute of Medicine. Dietary Reference Intakes: the essential guide to nutrient requirements. The National Academies Press, 2006.
17. Becker DV et al. Iodine supplementation for pregnancy and lactation – Unated States and Canada: recomendatons of the American Thyroid Association. Thyroid 2006; 16: 949–51.

В.Н.Прилепская, А.В.Ледина

ФГУ «Научный центр акушерства, гинекологии и перинатологии им. В.И.Кулакова»
Минздравсоцразвития РФ (дир. – акад. РАМН Г.Т.Сухих), Москва