Материалы доступны только для специалистов сферы здравоохранения.
Чтобы посмотреть материал полностью
Авторизуйтесь
или зарегистрируйтесь.
Морфофункциональные особенности эндометрия у больных эндометриозассоциированным бесплодием (обзор литературы)
Морфофункциональные особенности эндометрия у больных эндометриозассоциированным бесплодием (обзор литературы)
Материалы доступны только для специалистов сферы здравоохранения.
Чтобы посмотреть материал полностью
Авторизуйтесь
или зарегистрируйтесь.
Аннотация
В статье обсуждаются причины бесплодия у женщин с эндометриозом. Представлены основные изменения в пролиферативной фазе менструального цикла, рецептивности эндометрия, особенности децидуализации, апоптоза в эндометрии у женщин с эндометриозассоциированным бесплодием.
Ключевые слова: эндометриоз, бесплодие, рецептивность эндометрия, децидуализация, апоптоз.
Key words: endometriosis, infertility, endometrial receptivity, decidualization, apoptosis.
Ключевые слова: эндометриоз, бесплодие, рецептивность эндометрия, децидуализация, апоптоз.
________________________________________________
Key words: endometriosis, infertility, endometrial receptivity, decidualization, apoptosis.
Полный текст
Список литературы
1. Агаджанова Л. Эндометриальные пиноподии как маркеры имплантации человека. Проблемы репродукции. 2004; 10; 3: 6–11.
2. Адамян Л.В., Кулаков В.И., Андреева Е.Н. Эндометриозы. М.: Медици2006; с. 416.
3. Доброхотова Ю.В., Озерова Р.И., Рора Л.С. и др. Роль прогестеронзависимой иммуномодуляции и рецептивности эндометрия в невынашивании беременности. Проблемы репродукции. 2009; 5: 59–62.
4. Зайратьянц О.В., Адамян Л.В., Сонова М.М. и др. Экспрессия ароматазы цитохрома р-450 в эктопическом и эутопическом эндометрии при эндометриозе. Архив патологии. 2008; 5: 16–9.
5. Кулаков В.И., Волков Н.И., Смольникова В.Ю., Киндарова Л.Б. Современные подходы к лечению бесплодия, обусловленного генитальным эндометриозом, и программа ЭКО и ПЭ. Лечение женского и мужского бесплодия. Вспомогательные репродуктивные технологии. Под ред. В.И.Кулакова, Б.В.Леонова, Л.Н.Кузьмичева. М.: МИА, 2005.
6. Кулаков В.И., Манухин И.Б., Савельева Г.М. Гинекология: национальное руководство. М.: ГЭОТАР-Медиа, 2009.
7. Курило Л.Ф., Михалева Л.М., Адамян Л.В. и др. Количественный анализ состава фолликулов яичника при эндометриозе. Проблемы репродукции. 2006; 3: 53–6.
8. Михнина Е.А., Давыдова Н.И., Калинина Н.М., Эллиниди В.Н. Гормональные и иммунологические нарушения в формировании патологии эндометрия у женщин с наружным генитальным эндометриозом. Журн. акушерства и женских болезней. 2006; 15 (4): 87–100.
9. Aghajanova L, Stavreus-Evers A, Nikas Y et al. Coexpression of pinopodes and leukemia inhibitory factor, as well as its receptor, in human endometrium. Fertile Steril 2003; 79: 808–14.
10. Brosens J, Verhoeven H, Campo R et al. High endometrial aromatase P450 mRNA expression is associated with poor IVF outcome. Hum Reprod 2004; 2: 352–6.
11. Burney RO, Talbi S, Hamilton EA et al. Gene expression analysis of endometrium reveals progesterone resistance and candidate susceptibility genes in women with endometriosis. Endocrinology 2007; 148: 3814–26.
12. Daftary GS, Kayisli U, Seli E et al. Salpingectomy increases peri-implantation endometrial HOXA 10 expression in women with hydrosalpinx. Fertil Steril 2007; 87: 367–72.
13. Dheenadayalu K, Mak I, Gordts S et al. Aromatase p-450 messenger RNA expression in eutopic endometrium is not a specific marker for pelvic endometriosis. Fertil Steril 2002; 78: 825–9.
14. Dimitriadis E, Stoikos C, Stafford-Bell M et al. Interleukin-11, IL-11 receptoralpha and leukemia inhibitory factor are dysregulated in endometrium of infertile women with endometriosis during the implantation window. J Reprod Immunol 2006; 69: 53–64.
15. Dmowski WP, Ding J, Shen J et al. Apoptosis in endometrial glandular and stromal cells in women with and without endometriosis. Hum Reprod 2001; 16: 1802–8.
16. Donaghay M, Lessey BA. Uterine Receptivity: Alterations Associated with Benign Gynecological Disease. Semin Reprod Med 2007; 25: 461–75.
17. Garcia-Velasco JA, Mulayim N, Kayisli UA, Arici A. Elevated soluble Fas ligand levels may suggest a role for apoptosis in women with endometriosis. Fertil Steril 2002; 78: 855–9.
18. Garrido N, Navarro J, Pellicer A et al. The endometrium versus embrionic quality in endometriosis related infertility. Hum Reprod 2002; 8 (1): 95–103.
19. Genbacev OD, Pracobphol A, Foulk RA et al. Trophoblast L-Selectin-mediated adhesion at the maternal-fetal interface. Science 2003; 299: 405–8.
20. Gregory CW, Wilson EM, Apparao KB et al. Steroid receptor coactivator expression throughout the menstrual cycle in normal and abnormal endometrium. J Clin Endocrinol Metab 2002; 87: 2960–6.
21. Cakmak H, Taylor HS, Serdar E. Molecular Mechanisms of Treatment Resistance in Endometriosis: The Role of Progesterone–Hox Gene Interactions. Semin Reprod Med 2010; 28 (1): 69–74.
22. Achache H, Revel A. Endometrial receptivity markers, the journey to successful embryo implantation. Hum Reprod Update 2006; 12 (6): 731–46.
23. Harada T, Kaponis A, Iwabe T et al. Apoptosis in human endometrium and endometriosis. Hum Reprod Update 2004; 10 (1): 29–38.
24. Horne AW, Lalani EN, Margara RA et al. Mol Reprod Dev 2005; 72 (2): 216–29.
25. Jason GL, Aldad TS, Taylor HS. Defining the Proliferative Phase Endometrial Defect. Fertil Steril 2009; 91 (3): 698–704.
26. Klemmt PA, Carver JG, Kennedy SH et al. Stromal cells from endometriotic lesions and endometrium from women with endometriosis have reduced decidualization capacity. Fertil Steril 2006; 85: 564–72.
27. Klentzeris LD. Роль эндометрия в имплантации. Проблемы репродукции. 1999; 2: 27–33.
28. Lee B, Du H, Taylor HS. Experimental murine endometriosis induces DNA methylation and altered gene expression in eutopic endometrium. Biol Reprod 2009; 80: 79–85.
29. Lessey BA, Palomino WA, Apparao KBC et al. Estrogen receptor-alpha (ER- alpha) and defects in uterine receptivity in women. Reprod Biol Endocrinol 2006; 4 (Suppl. 1): S9.
30. Margarit L, Gonzalez D, Lewis PD et al. L-Selectin ligands in human endometrium: comparison of fertile and infertile subjects. Hum Reprod 2009; 11: 2767–77.
31. Margarit L, Taylor A, Roberts MH et al. MUC1 as a Discriminator between Endometrium from Fertile and Infertile Patients with PCOS and Endometriosis. J Clin Endocrinol Metab 2010; 95 (12): 5320–9.
32. Meresman GF, Vighi S, Buquet RA et al. Apoptosis and expression of Bcl-2, Bax in eutopic endometrium from women with endometriosis. Fertil Steril 2000; 74: 760–6.
33. Mikolajczyk M, Wirstlein P, Skrzypczak J. Leukaemia inhibitory factor and interleukin 11 levels in uterine flushings of infertile patients with endometriosis. Hum Reprod Sept 2006; 12: 3054–8.
34. Minici F, Tiberi F, Tropea A et al. Endometriosis and human infertility: a new investigation into the role of eutopic endometrium. Hum Reprod 2008; 3: 530–7.
35. Klemmt AB, Carver JG, Kennedy SH et al. Stromal cells from endometriotic lesions and endometrium from women with endometriosis have reduced decidualization capacity. Fertil Steril 2006; 85 (3): 564–72.
36. Qingxiang Wei MA, St. Clair JB et al. Reduced expression of biomarkers associated with the implantation window in women with endometriosis. Fertil Steril 2009; 91 (5): 1686–91.
37. Rackow BW, Taylor HS. Submucosal uterine leiomyomas have a global effect on molecular determinants of endometrial receptivity. Fertil Steril 2010; 93: 2027–34.
38. Matsuzaki S, Darcha C, Maleysson E et al. Impaired Down-Regulation of E-Cadherin and b-Catenin Protein Expression in Endometrial Epithelial Cells in the Mid-Secretory Endometrium of Infertile Patients with Endometriosis. J Clin Endocrinol Metab 2010; 95 (7): 3437–45.
39. Matsuzaki S, Canis M et al. Экспрессия НОХА-10 в эндометрии середины секреторной фазы у пациенток с бесплодием, ассоциированным с эндометриозом или миомой матки и бесплодием неясного генеза. Репродукция человека. 2010; 14 (2): 91–8.
40. Sarno JL, Kliman HJ, Taylor HS. HOXA 10, Pbx2, and Meis 1 protein expression in the human endometrium: formation of multimeric complexes on HOXA 10 target genes. J Clin Endocrinol Metab 2005; 90: 522–8.
41. Vitiello D, Kodaman PH, Taylor HS. HOX genes in implantation. Semin Reprod Med 2007; 25: 431–6.
2. Адамян Л.В., Кулаков В.И., Андреева Е.Н. Эндометриозы. М.: Медици2006; с. 416.
3. Доброхотова Ю.В., Озерова Р.И., Рора Л.С. и др. Роль прогестеронзависимой иммуномодуляции и рецептивности эндометрия в невынашивании беременности. Проблемы репродукции. 2009; 5: 59–62.
4. Зайратьянц О.В., Адамян Л.В., Сонова М.М. и др. Экспрессия ароматазы цитохрома р-450 в эктопическом и эутопическом эндометрии при эндометриозе. Архив патологии. 2008; 5: 16–9.
5. Кулаков В.И., Волков Н.И., Смольникова В.Ю., Киндарова Л.Б. Современные подходы к лечению бесплодия, обусловленного генитальным эндометриозом, и программа ЭКО и ПЭ. Лечение женского и мужского бесплодия. Вспомогательные репродуктивные технологии. Под ред. В.И.Кулакова, Б.В.Леонова, Л.Н.Кузьмичева. М.: МИА, 2005.
6. Кулаков В.И., Манухин И.Б., Савельева Г.М. Гинекология: национальное руководство. М.: ГЭОТАР-Медиа, 2009.
7. Курило Л.Ф., Михалева Л.М., Адамян Л.В. и др. Количественный анализ состава фолликулов яичника при эндометриозе. Проблемы репродукции. 2006; 3: 53–6.
8. Михнина Е.А., Давыдова Н.И., Калинина Н.М., Эллиниди В.Н. Гормональные и иммунологические нарушения в формировании патологии эндометрия у женщин с наружным генитальным эндометриозом. Журн. акушерства и женских болезней. 2006; 15 (4): 87–100.
9. Aghajanova L, Stavreus-Evers A, Nikas Y et al. Coexpression of pinopodes and leukemia inhibitory factor, as well as its receptor, in human endometrium. Fertile Steril 2003; 79: 808–14.
10. Brosens J, Verhoeven H, Campo R et al. High endometrial aromatase P450 mRNA expression is associated with poor IVF outcome. Hum Reprod 2004; 2: 352–6.
11. Burney RO, Talbi S, Hamilton EA et al. Gene expression analysis of endometrium reveals progesterone resistance and candidate susceptibility genes in women with endometriosis. Endocrinology 2007; 148: 3814–26.
12. Daftary GS, Kayisli U, Seli E et al. Salpingectomy increases peri-implantation endometrial HOXA 10 expression in women with hydrosalpinx. Fertil Steril 2007; 87: 367–72.
13. Dheenadayalu K, Mak I, Gordts S et al. Aromatase p-450 messenger RNA expression in eutopic endometrium is not a specific marker for pelvic endometriosis. Fertil Steril 2002; 78: 825–9.
14. Dimitriadis E, Stoikos C, Stafford-Bell M et al. Interleukin-11, IL-11 receptoralpha and leukemia inhibitory factor are dysregulated in endometrium of infertile women with endometriosis during the implantation window. J Reprod Immunol 2006; 69: 53–64.
15. Dmowski WP, Ding J, Shen J et al. Apoptosis in endometrial glandular and stromal cells in women with and without endometriosis. Hum Reprod 2001; 16: 1802–8.
16. Donaghay M, Lessey BA. Uterine Receptivity: Alterations Associated with Benign Gynecological Disease. Semin Reprod Med 2007; 25: 461–75.
17. Garcia-Velasco JA, Mulayim N, Kayisli UA, Arici A. Elevated soluble Fas ligand levels may suggest a role for apoptosis in women with endometriosis. Fertil Steril 2002; 78: 855–9.
18. Garrido N, Navarro J, Pellicer A et al. The endometrium versus embrionic quality in endometriosis related infertility. Hum Reprod 2002; 8 (1): 95–103.
19. Genbacev OD, Pracobphol A, Foulk RA et al. Trophoblast L-Selectin-mediated adhesion at the maternal-fetal interface. Science 2003; 299: 405–8.
20. Gregory CW, Wilson EM, Apparao KB et al. Steroid receptor coactivator expression throughout the menstrual cycle in normal and abnormal endometrium. J Clin Endocrinol Metab 2002; 87: 2960–6.
21. Cakmak H, Taylor HS, Serdar E. Molecular Mechanisms of Treatment Resistance in Endometriosis: The Role of Progesterone–Hox Gene Interactions. Semin Reprod Med 2010; 28 (1): 69–74.
22. Achache H, Revel A. Endometrial receptivity markers, the journey to successful embryo implantation. Hum Reprod Update 2006; 12 (6): 731–46.
23. Harada T, Kaponis A, Iwabe T et al. Apoptosis in human endometrium and endometriosis. Hum Reprod Update 2004; 10 (1): 29–38.
24. Horne AW, Lalani EN, Margara RA et al. Mol Reprod Dev 2005; 72 (2): 216–29.
25. Jason GL, Aldad TS, Taylor HS. Defining the Proliferative Phase Endometrial Defect. Fertil Steril 2009; 91 (3): 698–704.
26. Klemmt PA, Carver JG, Kennedy SH et al. Stromal cells from endometriotic lesions and endometrium from women with endometriosis have reduced decidualization capacity. Fertil Steril 2006; 85: 564–72.
27. Klentzeris LD. Роль эндометрия в имплантации. Проблемы репродукции. 1999; 2: 27–33.
28. Lee B, Du H, Taylor HS. Experimental murine endometriosis induces DNA methylation and altered gene expression in eutopic endometrium. Biol Reprod 2009; 80: 79–85.
29. Lessey BA, Palomino WA, Apparao KBC et al. Estrogen receptor-alpha (ER- alpha) and defects in uterine receptivity in women. Reprod Biol Endocrinol 2006; 4 (Suppl. 1): S9.
30. Margarit L, Gonzalez D, Lewis PD et al. L-Selectin ligands in human endometrium: comparison of fertile and infertile subjects. Hum Reprod 2009; 11: 2767–77.
31. Margarit L, Taylor A, Roberts MH et al. MUC1 as a Discriminator between Endometrium from Fertile and Infertile Patients with PCOS and Endometriosis. J Clin Endocrinol Metab 2010; 95 (12): 5320–9.
32. Meresman GF, Vighi S, Buquet RA et al. Apoptosis and expression of Bcl-2, Bax in eutopic endometrium from women with endometriosis. Fertil Steril 2000; 74: 760–6.
33. Mikolajczyk M, Wirstlein P, Skrzypczak J. Leukaemia inhibitory factor and interleukin 11 levels in uterine flushings of infertile patients with endometriosis. Hum Reprod Sept 2006; 12: 3054–8.
34. Minici F, Tiberi F, Tropea A et al. Endometriosis and human infertility: a new investigation into the role of eutopic endometrium. Hum Reprod 2008; 3: 530–7.
35. Klemmt AB, Carver JG, Kennedy SH et al. Stromal cells from endometriotic lesions and endometrium from women with endometriosis have reduced decidualization capacity. Fertil Steril 2006; 85 (3): 564–72.
36. Qingxiang Wei MA, St. Clair JB et al. Reduced expression of biomarkers associated with the implantation window in women with endometriosis. Fertil Steril 2009; 91 (5): 1686–91.
37. Rackow BW, Taylor HS. Submucosal uterine leiomyomas have a global effect on molecular determinants of endometrial receptivity. Fertil Steril 2010; 93: 2027–34.
38. Matsuzaki S, Darcha C, Maleysson E et al. Impaired Down-Regulation of E-Cadherin and b-Catenin Protein Expression in Endometrial Epithelial Cells in the Mid-Secretory Endometrium of Infertile Patients with Endometriosis. J Clin Endocrinol Metab 2010; 95 (7): 3437–45.
39. Matsuzaki S, Canis M et al. Экспрессия НОХА-10 в эндометрии середины секреторной фазы у пациенток с бесплодием, ассоциированным с эндометриозом или миомой матки и бесплодием неясного генеза. Репродукция человека. 2010; 14 (2): 91–8.
40. Sarno JL, Kliman HJ, Taylor HS. HOXA 10, Pbx2, and Meis 1 protein expression in the human endometrium: formation of multimeric complexes on HOXA 10 target genes. J Clin Endocrinol Metab 2005; 90: 522–8.
41. Vitiello D, Kodaman PH, Taylor HS. HOX genes in implantation. Semin Reprod Med 2007; 25: 431–6.
2. Адамян Л.В., Кулаков В.И., Андреева Е.Н. Эндометриозы. М.: Медици2006; с. 416.
3. Доброхотова Ю.В., Озерова Р.И., Рора Л.С. и др. Роль прогестеронзависимой иммуномодуляции и рецептивности эндометрия в невынашивании беременности. Проблемы репродукции. 2009; 5: 59–62.
4. Зайратьянц О.В., Адамян Л.В., Сонова М.М. и др. Экспрессия ароматазы цитохрома р-450 в эктопическом и эутопическом эндометрии при эндометриозе. Архив патологии. 2008; 5: 16–9.
5. Кулаков В.И., Волков Н.И., Смольникова В.Ю., Киндарова Л.Б. Современные подходы к лечению бесплодия, обусловленного генитальным эндометриозом, и программа ЭКО и ПЭ. Лечение женского и мужского бесплодия. Вспомогательные репродуктивные технологии. Под ред. В.И.Кулакова, Б.В.Леонова, Л.Н.Кузьмичева. М.: МИА, 2005.
6. Кулаков В.И., Манухин И.Б., Савельева Г.М. Гинекология: национальное руководство. М.: ГЭОТАР-Медиа, 2009.
7. Курило Л.Ф., Михалева Л.М., Адамян Л.В. и др. Количественный анализ состава фолликулов яичника при эндометриозе. Проблемы репродукции. 2006; 3: 53–6.
8. Михнина Е.А., Давыдова Н.И., Калинина Н.М., Эллиниди В.Н. Гормональные и иммунологические нарушения в формировании патологии эндометрия у женщин с наружным генитальным эндометриозом. Журн. акушерства и женских болезней. 2006; 15 (4): 87–100.
9. Aghajanova L, Stavreus-Evers A, Nikas Y et al. Coexpression of pinopodes and leukemia inhibitory factor, as well as its receptor, in human endometrium. Fertile Steril 2003; 79: 808–14.
10. Brosens J, Verhoeven H, Campo R et al. High endometrial aromatase P450 mRNA expression is associated with poor IVF outcome. Hum Reprod 2004; 2: 352–6.
11. Burney RO, Talbi S, Hamilton EA et al. Gene expression analysis of endometrium reveals progesterone resistance and candidate susceptibility genes in women with endometriosis. Endocrinology 2007; 148: 3814–26.
12. Daftary GS, Kayisli U, Seli E et al. Salpingectomy increases peri-implantation endometrial HOXA 10 expression in women with hydrosalpinx. Fertil Steril 2007; 87: 367–72.
13. Dheenadayalu K, Mak I, Gordts S et al. Aromatase p-450 messenger RNA expression in eutopic endometrium is not a specific marker for pelvic endometriosis. Fertil Steril 2002; 78: 825–9.
14. Dimitriadis E, Stoikos C, Stafford-Bell M et al. Interleukin-11, IL-11 receptoralpha and leukemia inhibitory factor are dysregulated in endometrium of infertile women with endometriosis during the implantation window. J Reprod Immunol 2006; 69: 53–64.
15. Dmowski WP, Ding J, Shen J et al. Apoptosis in endometrial glandular and stromal cells in women with and without endometriosis. Hum Reprod 2001; 16: 1802–8.
16. Donaghay M, Lessey BA. Uterine Receptivity: Alterations Associated with Benign Gynecological Disease. Semin Reprod Med 2007; 25: 461–75.
17. Garcia-Velasco JA, Mulayim N, Kayisli UA, Arici A. Elevated soluble Fas ligand levels may suggest a role for apoptosis in women with endometriosis. Fertil Steril 2002; 78: 855–9.
18. Garrido N, Navarro J, Pellicer A et al. The endometrium versus embrionic quality in endometriosis related infertility. Hum Reprod 2002; 8 (1): 95–103.
19. Genbacev OD, Pracobphol A, Foulk RA et al. Trophoblast L-Selectin-mediated adhesion at the maternal-fetal interface. Science 2003; 299: 405–8.
20. Gregory CW, Wilson EM, Apparao KB et al. Steroid receptor coactivator expression throughout the menstrual cycle in normal and abnormal endometrium. J Clin Endocrinol Metab 2002; 87: 2960–6.
21. Cakmak H, Taylor HS, Serdar E. Molecular Mechanisms of Treatment Resistance in Endometriosis: The Role of Progesterone–Hox Gene Interactions. Semin Reprod Med 2010; 28 (1): 69–74.
22. Achache H, Revel A. Endometrial receptivity markers, the journey to successful embryo implantation. Hum Reprod Update 2006; 12 (6): 731–46.
23. Harada T, Kaponis A, Iwabe T et al. Apoptosis in human endometrium and endometriosis. Hum Reprod Update 2004; 10 (1): 29–38.
24. Horne AW, Lalani EN, Margara RA et al. Mol Reprod Dev 2005; 72 (2): 216–29.
25. Jason GL, Aldad TS, Taylor HS. Defining the Proliferative Phase Endometrial Defect. Fertil Steril 2009; 91 (3): 698–704.
26. Klemmt PA, Carver JG, Kennedy SH et al. Stromal cells from endometriotic lesions and endometrium from women with endometriosis have reduced decidualization capacity. Fertil Steril 2006; 85: 564–72.
27. Klentzeris LD. Роль эндометрия в имплантации. Проблемы репродукции. 1999; 2: 27–33.
28. Lee B, Du H, Taylor HS. Experimental murine endometriosis induces DNA methylation and altered gene expression in eutopic endometrium. Biol Reprod 2009; 80: 79–85.
29. Lessey BA, Palomino WA, Apparao KBC et al. Estrogen receptor-alpha (ER- alpha) and defects in uterine receptivity in women. Reprod Biol Endocrinol 2006; 4 (Suppl. 1): S9.
30. Margarit L, Gonzalez D, Lewis PD et al. L-Selectin ligands in human endometrium: comparison of fertile and infertile subjects. Hum Reprod 2009; 11: 2767–77.
31. Margarit L, Taylor A, Roberts MH et al. MUC1 as a Discriminator between Endometrium from Fertile and Infertile Patients with PCOS and Endometriosis. J Clin Endocrinol Metab 2010; 95 (12): 5320–9.
32. Meresman GF, Vighi S, Buquet RA et al. Apoptosis and expression of Bcl-2, Bax in eutopic endometrium from women with endometriosis. Fertil Steril 2000; 74: 760–6.
33. Mikolajczyk M, Wirstlein P, Skrzypczak J. Leukaemia inhibitory factor and interleukin 11 levels in uterine flushings of infertile patients with endometriosis. Hum Reprod Sept 2006; 12: 3054–8.
34. Minici F, Tiberi F, Tropea A et al. Endometriosis and human infertility: a new investigation into the role of eutopic endometrium. Hum Reprod 2008; 3: 530–7.
35. Klemmt AB, Carver JG, Kennedy SH et al. Stromal cells from endometriotic lesions and endometrium from women with endometriosis have reduced decidualization capacity. Fertil Steril 2006; 85 (3): 564–72.
36. Qingxiang Wei MA, St. Clair JB et al. Reduced expression of biomarkers associated with the implantation window in women with endometriosis. Fertil Steril 2009; 91 (5): 1686–91.
37. Rackow BW, Taylor HS. Submucosal uterine leiomyomas have a global effect on molecular determinants of endometrial receptivity. Fertil Steril 2010; 93: 2027–34.
38. Matsuzaki S, Darcha C, Maleysson E et al. Impaired Down-Regulation of E-Cadherin and b-Catenin Protein Expression in Endometrial Epithelial Cells in the Mid-Secretory Endometrium of Infertile Patients with Endometriosis. J Clin Endocrinol Metab 2010; 95 (7): 3437–45.
39. Matsuzaki S, Canis M et al. Экспрессия НОХА-10 в эндометрии середины секреторной фазы у пациенток с бесплодием, ассоциированным с эндометриозом или миомой матки и бесплодием неясного генеза. Репродукция человека. 2010; 14 (2): 91–8.
40. Sarno JL, Kliman HJ, Taylor HS. HOXA 10, Pbx2, and Meis 1 protein expression in the human endometrium: formation of multimeric complexes on HOXA 10 target genes. J Clin Endocrinol Metab 2005; 90: 522–8.
41. Vitiello D, Kodaman PH, Taylor HS. HOX genes in implantation. Semin Reprod Med 2007; 25: 431–6.
________________________________________________
2. Адамян Л.В., Кулаков В.И., Андреева Е.Н. Эндометриозы. М.: Медици2006; с. 416.
3. Доброхотова Ю.В., Озерова Р.И., Рора Л.С. и др. Роль прогестеронзависимой иммуномодуляции и рецептивности эндометрия в невынашивании беременности. Проблемы репродукции. 2009; 5: 59–62.
4. Зайратьянц О.В., Адамян Л.В., Сонова М.М. и др. Экспрессия ароматазы цитохрома р-450 в эктопическом и эутопическом эндометрии при эндометриозе. Архив патологии. 2008; 5: 16–9.
5. Кулаков В.И., Волков Н.И., Смольникова В.Ю., Киндарова Л.Б. Современные подходы к лечению бесплодия, обусловленного генитальным эндометриозом, и программа ЭКО и ПЭ. Лечение женского и мужского бесплодия. Вспомогательные репродуктивные технологии. Под ред. В.И.Кулакова, Б.В.Леонова, Л.Н.Кузьмичева. М.: МИА, 2005.
6. Кулаков В.И., Манухин И.Б., Савельева Г.М. Гинекология: национальное руководство. М.: ГЭОТАР-Медиа, 2009.
7. Курило Л.Ф., Михалева Л.М., Адамян Л.В. и др. Количественный анализ состава фолликулов яичника при эндометриозе. Проблемы репродукции. 2006; 3: 53–6.
8. Михнина Е.А., Давыдова Н.И., Калинина Н.М., Эллиниди В.Н. Гормональные и иммунологические нарушения в формировании патологии эндометрия у женщин с наружным генитальным эндометриозом. Журн. акушерства и женских болезней. 2006; 15 (4): 87–100.
9. Aghajanova L, Stavreus-Evers A, Nikas Y et al. Coexpression of pinopodes and leukemia inhibitory factor, as well as its receptor, in human endometrium. Fertile Steril 2003; 79: 808–14.
10. Brosens J, Verhoeven H, Campo R et al. High endometrial aromatase P450 mRNA expression is associated with poor IVF outcome. Hum Reprod 2004; 2: 352–6.
11. Burney RO, Talbi S, Hamilton EA et al. Gene expression analysis of endometrium reveals progesterone resistance and candidate susceptibility genes in women with endometriosis. Endocrinology 2007; 148: 3814–26.
12. Daftary GS, Kayisli U, Seli E et al. Salpingectomy increases peri-implantation endometrial HOXA 10 expression in women with hydrosalpinx. Fertil Steril 2007; 87: 367–72.
13. Dheenadayalu K, Mak I, Gordts S et al. Aromatase p-450 messenger RNA expression in eutopic endometrium is not a specific marker for pelvic endometriosis. Fertil Steril 2002; 78: 825–9.
14. Dimitriadis E, Stoikos C, Stafford-Bell M et al. Interleukin-11, IL-11 receptoralpha and leukemia inhibitory factor are dysregulated in endometrium of infertile women with endometriosis during the implantation window. J Reprod Immunol 2006; 69: 53–64.
15. Dmowski WP, Ding J, Shen J et al. Apoptosis in endometrial glandular and stromal cells in women with and without endometriosis. Hum Reprod 2001; 16: 1802–8.
16. Donaghay M, Lessey BA. Uterine Receptivity: Alterations Associated with Benign Gynecological Disease. Semin Reprod Med 2007; 25: 461–75.
17. Garcia-Velasco JA, Mulayim N, Kayisli UA, Arici A. Elevated soluble Fas ligand levels may suggest a role for apoptosis in women with endometriosis. Fertil Steril 2002; 78: 855–9.
18. Garrido N, Navarro J, Pellicer A et al. The endometrium versus embrionic quality in endometriosis related infertility. Hum Reprod 2002; 8 (1): 95–103.
19. Genbacev OD, Pracobphol A, Foulk RA et al. Trophoblast L-Selectin-mediated adhesion at the maternal-fetal interface. Science 2003; 299: 405–8.
20. Gregory CW, Wilson EM, Apparao KB et al. Steroid receptor coactivator expression throughout the menstrual cycle in normal and abnormal endometrium. J Clin Endocrinol Metab 2002; 87: 2960–6.
21. Cakmak H, Taylor HS, Serdar E. Molecular Mechanisms of Treatment Resistance in Endometriosis: The Role of Progesterone–Hox Gene Interactions. Semin Reprod Med 2010; 28 (1): 69–74.
22. Achache H, Revel A. Endometrial receptivity markers, the journey to successful embryo implantation. Hum Reprod Update 2006; 12 (6): 731–46.
23. Harada T, Kaponis A, Iwabe T et al. Apoptosis in human endometrium and endometriosis. Hum Reprod Update 2004; 10 (1): 29–38.
24. Horne AW, Lalani EN, Margara RA et al. Mol Reprod Dev 2005; 72 (2): 216–29.
25. Jason GL, Aldad TS, Taylor HS. Defining the Proliferative Phase Endometrial Defect. Fertil Steril 2009; 91 (3): 698–704.
26. Klemmt PA, Carver JG, Kennedy SH et al. Stromal cells from endometriotic lesions and endometrium from women with endometriosis have reduced decidualization capacity. Fertil Steril 2006; 85: 564–72.
27. Klentzeris LD. Роль эндометрия в имплантации. Проблемы репродукции. 1999; 2: 27–33.
28. Lee B, Du H, Taylor HS. Experimental murine endometriosis induces DNA methylation and altered gene expression in eutopic endometrium. Biol Reprod 2009; 80: 79–85.
29. Lessey BA, Palomino WA, Apparao KBC et al. Estrogen receptor-alpha (ER- alpha) and defects in uterine receptivity in women. Reprod Biol Endocrinol 2006; 4 (Suppl. 1): S9.
30. Margarit L, Gonzalez D, Lewis PD et al. L-Selectin ligands in human endometrium: comparison of fertile and infertile subjects. Hum Reprod 2009; 11: 2767–77.
31. Margarit L, Taylor A, Roberts MH et al. MUC1 as a Discriminator between Endometrium from Fertile and Infertile Patients with PCOS and Endometriosis. J Clin Endocrinol Metab 2010; 95 (12): 5320–9.
32. Meresman GF, Vighi S, Buquet RA et al. Apoptosis and expression of Bcl-2, Bax in eutopic endometrium from women with endometriosis. Fertil Steril 2000; 74: 760–6.
33. Mikolajczyk M, Wirstlein P, Skrzypczak J. Leukaemia inhibitory factor and interleukin 11 levels in uterine flushings of infertile patients with endometriosis. Hum Reprod Sept 2006; 12: 3054–8.
34. Minici F, Tiberi F, Tropea A et al. Endometriosis and human infertility: a new investigation into the role of eutopic endometrium. Hum Reprod 2008; 3: 530–7.
35. Klemmt AB, Carver JG, Kennedy SH et al. Stromal cells from endometriotic lesions and endometrium from women with endometriosis have reduced decidualization capacity. Fertil Steril 2006; 85 (3): 564–72.
36. Qingxiang Wei MA, St. Clair JB et al. Reduced expression of biomarkers associated with the implantation window in women with endometriosis. Fertil Steril 2009; 91 (5): 1686–91.
37. Rackow BW, Taylor HS. Submucosal uterine leiomyomas have a global effect on molecular determinants of endometrial receptivity. Fertil Steril 2010; 93: 2027–34.
38. Matsuzaki S, Darcha C, Maleysson E et al. Impaired Down-Regulation of E-Cadherin and b-Catenin Protein Expression in Endometrial Epithelial Cells in the Mid-Secretory Endometrium of Infertile Patients with Endometriosis. J Clin Endocrinol Metab 2010; 95 (7): 3437–45.
39. Matsuzaki S, Canis M et al. Экспрессия НОХА-10 в эндометрии середины секреторной фазы у пациенток с бесплодием, ассоциированным с эндометриозом или миомой матки и бесплодием неясного генеза. Репродукция человека. 2010; 14 (2): 91–8.
40. Sarno JL, Kliman HJ, Taylor HS. HOXA 10, Pbx2, and Meis 1 protein expression in the human endometrium: formation of multimeric complexes on HOXA 10 target genes. J Clin Endocrinol Metab 2005; 90: 522–8.
41. Vitiello D, Kodaman PH, Taylor HS. HOX genes in implantation. Semin Reprod Med 2007; 25: 431–6.
Авторы
А.В.Колотовкина, Е.А.Калинина, Е.А.Коган
ФГБУ Научный центр акушерства, гинекологии и перинатологии им. акад. В.И.Кулакова Минздрава РФ, Москва
ФГБУ Научный центр акушерства, гинекологии и перинатологии им. акад. В.И.Кулакова Минздрава РФ, Москва
________________________________________________
Цель портала OmniDoctor – предоставление профессиональной информации врачам, провизорам и фармацевтам.