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Опыт медикаментозного прерывания беременности у пациенток со злокачественными заболеваниями
Опыт медикаментозного прерывания беременности у пациенток со злокачественными заболеваниями
Доброхотова Ю.Э., Аракелов С.Э., Данелян С.Ж. и др. Опыт медикаментозного прерывания беременности у пациенток со злокачественными заболеваниями. Гинекология. 2017; 19 (2): 75–78.
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Аннотация
Распространенность и частота выявления опухолей, ассоциированных с беременностью, неуклонно растет. Выявление злокачественного новообразования всегда ставит врача перед необходимостью принятия решения о возможности и целесообразности сохранения беременности. Определяющим моментом являются характер и стадия патологического процесса и срок беременности. Согласно приказу Министерства здравоохранения и социального развития РФ от 3 декабря 2007 г. №736 «Об утверждении перечня медицинских показаний для искусственного прерывания беременности», в случае выявления новообразования, требующего проведения химиотерапии или лучевой терапии на область малого таза при коде заболевания С51–С58, показано прерывание беременности. Во всех других случаях вопрос о прерывании беременности решается индивидуально консилиумом врачей. В статье представлены кинические случаи медикаментозного прерывания беременности у пациенток со сроком гестации до 20 нед.
Ключевые слова: рак, беременность, опухоль, ассоциированная с беременностью, артифициальный аборт, мифепристон, мизопростол.
Key words: cancer, pregnancy, tumor associated with pregnancy, artificial abortion, mifepristone, misoprostol.
Ключевые слова: рак, беременность, опухоль, ассоциированная с беременностью, артифициальный аборт, мифепристон, мизопростол.
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Key words: cancer, pregnancy, tumor associated with pregnancy, artificial abortion, mifepristone, misoprostol.
Полный текст
Список литературы
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2. www.bt.cdc.gov/radiation/prenatalphysician.asp
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7. Azim HA, Bellettini G, Liptrott SJ. Breastfeeding in breast cancer survivors: pattern, behavior and effect on breast cancer outcome. Ann Oncol 2010; 21 (Suppl. 8): viii89.
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10. Dede M, Yenen MC, Yilmaz A. Treatment of incidental adnexal masses at cesarean section: a retrospective study. Int J Gynecol Cancer 2007; 17: 339.
11. Goff BA, Mandel LS, Drescher CW. Development of an ovarian cancer symptom index: possibilities for earlier detection. Cancer 2007; 109: 221.
12. Yen CF, Lin SL, Murk W. Risk analysis of torsion and malignancy for adnexal masses during pregnancy. Fertil Steril 2009; 91: 1895.
13. Sarandakou A, Protonotariou E, Rizos D. Tumor markers in biological fluids associated with pregnancy. Crit Rev Clin Lab Sci 2007; 44: 151.
14. Giuntoli RL 2nd, Vang RS, Bristow RE. Evaluation and management of adnexal masses during pregnancy. Clin Obstet Gynecol 2006; 49: 492.
15. Yakasai IA, Bappa LA. Diagnosis and management of adnexal masses in pregnancy. J Surg Tech Case Rep 2012; 4: 79.
16. ACOG Committee on Obstetric Practice. ACOG Committee Opinion. Number 299, September 2004 (replaces No. 158, September 1995). Guidelines for diagnostic imaging during pregnancy. Obstet Gynecol 2004; 104: 647.
2. www.bt.cdc.gov/radiation/prenatalphysician.asp
3. Stensheim H, Moller B, van Dijk T, Fossa SD. Cause-specific survival for women diagnosed with cancer during pregnancy or lactation: a registry-based cohort study. J Clin Oncol 2009; 27: 45.
4. Vercellino GF, Koehler C, Erdemoglu E. Laparoscopic pelvic lymphadenectomy in 32 pregnant patients with cervical cancer: rationale, description of the technique, and outcome. Int J Gynecol Cancer 2014; 24: 364.
5. Amant F, von Minckwitz G, Han SN. Prognosis of women with primary breast cancer diagnosed during pregnancy: results from an international collaborative study. J Clin Oncol 2013; 31: 2532.
6. Azim HA Jr, Santoro L, Russell-Edu W. Prognosis of pregnancy-associated breast cancer: a meta-analysis of 30 studies. Cancer Treat Rev 2012; 38: 834.
7. Azim HA, Bellettini G, Liptrott SJ. Breastfeeding in breast cancer survivors: pattern, behavior and effect on breast cancer outcome. Ann Oncol 2010; 21 (Suppl. 8): viii89.
8. Leiserowitz GS, Xing G, Cress R. Adnexal masses in pregnancy: how often are they malignant? Gynecol Oncol 2006; 101: 315.
9. Palmer J, Vatish M, Tidy J. Epithelial ovarian cancer in pregnancy: a review of the literature. BJOG 2009; 116: 480.
10. Dede M, Yenen MC, Yilmaz A. Treatment of incidental adnexal masses at cesarean section: a retrospective study. Int J Gynecol Cancer 2007; 17: 339.
11. Goff BA, Mandel LS, Drescher CW. Development of an ovarian cancer symptom index: possibilities for earlier detection. Cancer 2007; 109: 221.
12. Yen CF, Lin SL, Murk W. Risk analysis of torsion and malignancy for adnexal masses during pregnancy. Fertil Steril 2009; 91: 1895.
13. Sarandakou A, Protonotariou E, Rizos D. Tumor markers in biological fluids associated with pregnancy. Crit Rev Clin Lab Sci 2007; 44: 151.
14. Giuntoli RL 2nd, Vang RS, Bristow RE. Evaluation and management of adnexal masses during pregnancy. Clin Obstet Gynecol 2006; 49: 492.
15. Yakasai IA, Bappa LA. Diagnosis and management of adnexal masses in pregnancy. J Surg Tech Case Rep 2012; 4: 79.
16. ACOG Committee on Obstetric Practice. ACOG Committee Opinion. Number 299, September 2004 (replaces No. 158, September 1995). Guidelines for diagnostic imaging during pregnancy. Obstet Gynecol 2004; 104: 647.
2. www.bt.cdc.gov/radiation/prenatalphysician.asp
3. Stensheim H, Moller B, van Dijk T, Fossa SD. Cause-specific survival for women diagnosed with cancer during pregnancy or lactation: a registry-based cohort study. J Clin Oncol 2009; 27: 45.
4. Vercellino GF, Koehler C, Erdemoglu E. Laparoscopic pelvic lymphadenectomy in 32 pregnant patients with cervical cancer: rationale, description of the technique, and outcome. Int J Gynecol Cancer 2014; 24: 364.
5. Amant F, von Minckwitz G, Han SN. Prognosis of women with primary breast cancer diagnosed during pregnancy: results from an international collaborative study. J Clin Oncol 2013; 31: 2532.
6. Azim HA Jr, Santoro L, Russell-Edu W. Prognosis of pregnancy-associated breast cancer: a meta-analysis of 30 studies. Cancer Treat Rev 2012; 38: 834.
7. Azim HA, Bellettini G, Liptrott SJ. Breastfeeding in breast cancer survivors: pattern, behavior and effect on breast cancer outcome. Ann Oncol 2010; 21 (Suppl. 8): viii89.
8. Leiserowitz GS, Xing G, Cress R. Adnexal masses in pregnancy: how often are they malignant? Gynecol Oncol 2006; 101: 315.
9. Palmer J, Vatish M, Tidy J. Epithelial ovarian cancer in pregnancy: a review of the literature. BJOG 2009; 116: 480.
10. Dede M, Yenen MC, Yilmaz A. Treatment of incidental adnexal masses at cesarean section: a retrospective study. Int J Gynecol Cancer 2007; 17: 339.
11. Goff BA, Mandel LS, Drescher CW. Development of an ovarian cancer symptom index: possibilities for earlier detection. Cancer 2007; 109: 221.
12. Yen CF, Lin SL, Murk W. Risk analysis of torsion and malignancy for adnexal masses during pregnancy. Fertil Steril 2009; 91: 1895.
13. Sarandakou A, Protonotariou E, Rizos D. Tumor markers in biological fluids associated with pregnancy. Crit Rev Clin Lab Sci 2007; 44: 151.
14. Giuntoli RL 2nd, Vang RS, Bristow RE. Evaluation and management of adnexal masses during pregnancy. Clin Obstet Gynecol 2006; 49: 492.
15. Yakasai IA, Bappa LA. Diagnosis and management of adnexal masses in pregnancy. J Surg Tech Case Rep 2012; 4: 79.
16. ACOG Committee on Obstetric Practice. ACOG Committee Opinion. Number 299, September 2004 (replaces No. 158, September 1995). Guidelines for diagnostic imaging during pregnancy. Obstet Gynecol 2004; 104: 647.
________________________________________________
2. www.bt.cdc.gov/radiation/prenatalphysician.asp
3. Stensheim H, Moller B, van Dijk T, Fossa SD. Cause-specific survival for women diagnosed with cancer during pregnancy or lactation: a registry-based cohort study. J Clin Oncol 2009; 27: 45.
4. Vercellino GF, Koehler C, Erdemoglu E. Laparoscopic pelvic lymphadenectomy in 32 pregnant patients with cervical cancer: rationale, description of the technique, and outcome. Int J Gynecol Cancer 2014; 24: 364.
5. Amant F, von Minckwitz G, Han SN. Prognosis of women with primary breast cancer diagnosed during pregnancy: results from an international collaborative study. J Clin Oncol 2013; 31: 2532.
6. Azim HA Jr, Santoro L, Russell-Edu W. Prognosis of pregnancy-associated breast cancer: a meta-analysis of 30 studies. Cancer Treat Rev 2012; 38: 834.
7. Azim HA, Bellettini G, Liptrott SJ. Breastfeeding in breast cancer survivors: pattern, behavior and effect on breast cancer outcome. Ann Oncol 2010; 21 (Suppl. 8): viii89.
8. Leiserowitz GS, Xing G, Cress R. Adnexal masses in pregnancy: how often are they malignant? Gynecol Oncol 2006; 101: 315.
9. Palmer J, Vatish M, Tidy J. Epithelial ovarian cancer in pregnancy: a review of the literature. BJOG 2009; 116: 480.
10. Dede M, Yenen MC, Yilmaz A. Treatment of incidental adnexal masses at cesarean section: a retrospective study. Int J Gynecol Cancer 2007; 17: 339.
11. Goff BA, Mandel LS, Drescher CW. Development of an ovarian cancer symptom index: possibilities for earlier detection. Cancer 2007; 109: 221.
12. Yen CF, Lin SL, Murk W. Risk analysis of torsion and malignancy for adnexal masses during pregnancy. Fertil Steril 2009; 91: 1895.
13. Sarandakou A, Protonotariou E, Rizos D. Tumor markers in biological fluids associated with pregnancy. Crit Rev Clin Lab Sci 2007; 44: 151.
14. Giuntoli RL 2nd, Vang RS, Bristow RE. Evaluation and management of adnexal masses during pregnancy. Clin Obstet Gynecol 2006; 49: 492.
15. Yakasai IA, Bappa LA. Diagnosis and management of adnexal masses in pregnancy. J Surg Tech Case Rep 2012; 4: 79.
16. ACOG Committee on Obstetric Practice. ACOG Committee Opinion. Number 299, September 2004 (replaces No. 158, September 1995). Guidelines for diagnostic imaging during pregnancy. Obstet Gynecol 2004; 104: 647.
Авторы
Ю.Э.Доброхотова1, С.Э.Аракелов2, С.Ж.Данелян2, Е.И.Боровкова*1, Е.В.Шайдуллина2
1. ФГБОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И.Пирогова» Минздрава России. 117997, Россия, Москва, ул. Островитянова, д. 1;
2. ГБУЗ «Городская клиническая больница №40» Департамента здравоохранения г. Москвы. 129301, Россия, Москва, ул. Касаткина, д. 7
*katyanikitina@mail.ru
1. N.I.Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation. 117997, Russian Federation, Moscow, ul. Ostrovitianova, d. 1;
2. City Clinical Hospital №40 of the Department of Health of Moscow. 129301, Russian Federation, Moscow, ul. Kasatkina, d. 7
*katyanikitina@mail.ru
1. ФГБОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И.Пирогова» Минздрава России. 117997, Россия, Москва, ул. Островитянова, д. 1;
2. ГБУЗ «Городская клиническая больница №40» Департамента здравоохранения г. Москвы. 129301, Россия, Москва, ул. Касаткина, д. 7
*katyanikitina@mail.ru
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1. N.I.Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation. 117997, Russian Federation, Moscow, ul. Ostrovitianova, d. 1;
2. City Clinical Hospital №40 of the Department of Health of Moscow. 129301, Russian Federation, Moscow, ul. Kasatkina, d. 7
*katyanikitina@mail.ru
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