Первичная дисменорея: стратегия и тактика лечения

Доброхотова Ю.Э., Боровкова Е.И., Залесская С.А. Первичная дисменорея: стратегия и тактика лечения. Гинекология. 2018; 20 (1): 31–34. DOI: 10.26442/2079-5696_20.1.31-34

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Dobrokhotova Yu.E., Borovkova E.I., Zalesskaia S.A. Primary dysmenorrhea: strategy and tactics of treatment. Gynecology. 2018; 20 (1): 31–34. DOI: 10.26442/2079-5696_20.1.31-34

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Аннотация

В статье обобщены результаты многочисленных рандомизированных исследований и структурирован подход к тактике ведения пациенток с первичной дисменореей. Стартовой терапией является назначение нестероидных противовоспалительных средств и/или эстроген-гестагенных препаратов. При отсутствии эффекта от терапии в течение 3 мес целесообразно перейти на препарат другой группы или комбинацию лекарств. Недостижение желаемого терапевтического результата в течение 6 мес является основанием для уточнения диагноза. Статья проиллюстрирована клиническим случаем ведения пациентки с первичной дисменореей.

Ключевые слова: дисменорея, нестероидные противовоспалительные препараты, комбинированные оральные контрацептивы, левоноргестрел, циклооксигеназа, простагландины, арахидоновая кислота.

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The article summarizes the results of numerous randomized studies and structured the approach to the tactics of managing patients with primary dysmenorrhea. The starting therapy is the administration of non-steroidal anti-inflammatory drugs and/or estrogen-progestational drugs. In the absence of the effect of therapy for 3 months, it is advisable to switch to a drug of another group or a combination of drugs. Failure to achieve the desired therapeutic result within 6 months is the basis for clarifying the diagnosis. The article is illustrated by the clinical case of a patient with primary dysmenorrhea.

Key words: dysmenorrhea, nonsteroidal anti-inflammatory drugs, combined oral contraceptives, levonorgestrel, cyclooxygenase, prostaglandins, arachidonic acid.

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Список литературы

1. Majoribanks J, Proctor M, Farquhar C et al. Nonsteroidal anti-inflammatory drugs for dysmenorrhoea (review). Cochrane Database Systematic Rev 2010; 20: 1.
2. Norman RJ. Reproductive consequences of COX-2 inhibition. Lancet 2001; 358: 1287.
3. Norman RJ, Wu R. The potential danger of COX-2 inhibitors. Fertil Steril 2004; 81: 493.
4. Andersch B, Milsom I. An epidemiologic study of young women with dysmenorrhea. Am J Obstet Gynecol 1982; 144: 655.
5. Fedele L, Marchini M, Acaia B et al. Dynamics and significance of placebo response in primary dysmenorrhea. Pain 1989; 36: 43.
6. Missmer SA, Hankinson SE, Spiegelman D et al. Incidence of laparoscopically confirmed endometriosis by demographic, anthropometric, and lifestyle factors. Am J Epidemiol 2004; 160: 784.
7. Marjoribanks J, Proctor M, Farquhar C, Derks RS. Nonsteroidal anti-inflammatory drugs for dysmenorrhoea. Cochrane Database Syst Rev 2010; CD001751.
8. Zahradnik HP, Hanjalic-Beck A, Groth K. Nonsteroidal anti-inflammatory drugs and hormonal contraceptives for pain relief from dysmenorrhea: a review. Contraception 2010; 81: 185.
9. Wong CL, Farquhar C, Roberts H, Proctor M. Oral contraceptive pill for primary dysmenorrhoea. Cochrane Database Syst Rev 2009; CD002120.
10. Petraglia F, Parke S, Serrani M et al. Estradiol valerate plus dienogest versus ethinylestradiol plus levonorgestrel for the treatment of primary dysmenorrhea. Int J Gynaecol Obstet 2014; 125: 270.
11. Davis AR, Westhoff C, O'Connell K, Gallagher N. Oral contraceptives for dysmenorrhea in adolescent girls: a randomized trial. Obstet Gynecol 2005; 106: 97.
12. Machado RB, de Melo NR, Maia H Jr. Bleeding patterns and menstrual-related symptoms with the continuous use of a contraceptive combination of ethinylestradiol and drospirenone: a randomized study. Contraception 2010; 81: 215.
13. Roumen FJ. The contraceptive vaginal ring compared with the combined oral contraceptive pill: a comprehensive review of randomized controlled trials. Contraception 2007; 75: 420.
14. Lindh I, Milsom I. The influence of intrauterine contraception on the prevalence and severity of dysmenorrhea: a longitudinal population study. Hum Reprod 2013; 28: 1953.
15. Walch K, Unfried G, Huber J et al. Implanon versus medroxyprogesterone acetate: effects on pain scores in patients with symptomatic endometriosis – a pilot study. Contraception 2009; 79: 29.
16. Morgan PJ, Kung R, Tarshis J. Nitroglycerin as a uterine relaxant: a systematic review. J Obstet Gynaecol Can 2002; 24: 403.
17. Proctor ML, Murphy PA. Herbal and dietary therapies for primary and secondary dysmenorrhoea. Cochrane Database Syst Rev 2001; CD002124.
18. Pattanittum P, Kunyanone N, Brown J et al. Dietary supplements for dysmenorrhoea. Cochrane Database Syst Rev 2016; 3: CD002124.
19. Barnard ND, Scialli AR, Hurlock D, Bertron P. Diet and sex-hormone binding globulin, dysmenorrhea, and premenstrual symptoms. Obstet Gynecol 2000; 95: 245.
20. Abdul-Razzak KK, Ayoub NM, Abu-Taleb AA, Obeidat BA. Influence of dietary intake of dairy products on dysmenorrhea. J Obstet Gynaecol Res 2010; 36: 377.
21. Akin M, Price W, Rodriguez G Jr et al. Continuous, low-level, topical heat wrap therapy as compared to acetaminophen for primary dysmenorrhea. J Reprod Med 2004; 49: 739.
22. Lee B, Hong SH, Kim K, et al. Efficacy of the device combining high-frequency transcutaneous electrical nerve stimulation and thermotherapy for relieving primary dysmenorrhea: a randomized, single-blind, placebo-controlled trial. Eur J Obstet Gynecol Reprod Biol 2015; 194: 58.
23. Golomb LM, Solidum AA, Warren MP. Primary dysmenorrhea and physical activity. Med Sci Sports Exerc 1998; 30: 906.
24. Brown J, Brown S. Exercise for dysmenorrhoea. Cochrane Database Syst Rev 2010; CD004142.
25. Yang NY, Kim SD. Effects of a Yoga Program on Menstrual Cramps and Menstrual Distress in Undergraduate Students with Primary Dysmenorrhea: A Single-Blind, Randomized Controlled Trial. J Altern Complement Med 2016; 22: 732.
26. Hatcher RA. Counseling couples about coitus during menstrual flow. Contracept Technol Update 1981; 2: 167.
27. Ziaei S, Zakeri M, Kazemnejad A. A randomised controlled trial of vitamin E in the treatment of primary dysmenorrhoea. BJOG 2005; 112: 466.
28. Daily JW, Zhang X, Kim DS, Park S. Efficacy of Ginger for Alleviating the Symptoms of Primary Dysmenorrhea: A Systematic Review and Meta-analysis of Randomized Clinical Trials. Pain Med 2015; 16: 2243.
29. Smith CA, Armour M, Zhu X, et al. Acupuncture for dysmenorrhoea. Cochrane Database Syst Rev 2016; 4: CD007854.
30. Zhu X, Proctor M, Bensoussan A et al. Chinese herbal medicine for primary dysmenorrhoea. Cochrane Database Syst Rev 2007; CD005288.

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Авторы

Ю.Э.Доброхотова, Е.И.Боровкова*, С.А.Залесская

ФГБОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И.Пирогова» Минздрава России. 117997, Россия, Москва, ул. Островитянова, д.1
*katyanikitina@mail.ru

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Yu.E.Dobrokhotova, E.I.Borovkova*, S.A.Zalesskaia

N.I.Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation. 117997, Russian Federation, Moscow, ul. Ostrovitianova, d. 1
*katyanikitina@mail.ru

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