Цель обзора литературы – представление клинических научных данных, основанных на современных доказательствах информации, о ведении пациенток со стрессовым недержанием мочи, эффективности и безопасности периуретральных инъекций различных объемообразующих веществ. Материал и методы. Проведен обзор отечественных и зарубежных источников, посвященных распространенности, этиопатогенезу и принципам лечения стрессового недержания мочи у женщин, в частности инъекционному методу. Результаты. Приведены данные об этиопатогенезе, диагностике и методах лечения стрессового недержания мочи у женщин в зависимости от степени тяжести патологии. Проанализированы данные о периуретральных инъекциях различных объемообразующих материалов, их эффективности и безопасности. Ключевые слова: стрессовое недержание мочи, недержание мочи при напряжении, периуретральное введение объемообразующих веществ, слинговые операции, биологическая обратная связь.
________________________________________________
The purpose of the review – presentation of clinical scientific data based on current evidence of information on the management of patients with stress urinary incontinence, the effectiveness and safety of periurethral injections of various bulking substances. Material and methods. А review of Russian and foreign sources on the prevalence, etiopathogenesis, diagnosis and treatment of stress urinary incontinence in women, in particular the injection method. Results. The review presents data of the etiopathogenesis, diagnosis and treatment of stress urinary incontinence in women, depending on the severity of the pathology. Analyzed the data of periurethral injection of various bulking materials, their effectiveness and safety. Key words: stress urinary incontinence, the introduction of periurethral bulking substances, sling surgery, biofeedback.
1. Monz D, Pons M, Hampel C et al. Patien – repoted impact of urinary incontinence. Results from treatment seeking women in 14 European countries. Maturitas 2005; 52 (2): 25–8.
2. Hampel C, Weinhold D, Benken N et al. Prevalence and Natural History of Female Incontinence. Eur Urol 2007; 32 (Suppl. 2): 3–12.
3. Ермакова Е.И., Балан В.Е. Урогенитальные нарушения у женщин в климактерии: оптимизация методов лечения. Акуш. и гинекол. 2013; 3: 85–9. / Ermakova E.I., Balan V.E. Urogenital'nye narusheniia u zhenshchin v klimakterii: optimizatsiia metodov lecheniia. Akush. i ginekol. 2013; 3: 85–9.
4. Raz S. Vaginal surgery for stress incontinence. J Am Geriatr Soc 1990; 38: 345–7.
5. Blaivas JG, Olsson CA. Stress incontinence classification and surgical approach. J Urol 1988; 139: 737.
6. Кан Д.В. Руководство по акушерской и гинекологической урологии. 2-е изд., перераб. и доп. М.: Медицина, 1986; с. 486–95. / Kan D.V. Rukovodstvo po akusherskoi i ginekologicheskoi urologii. 2-e izd., pererab. i dop. M.: Meditsina, 1986; s. 486–95. [in Russian]
7. Hansen MF. Surgical treatment for urinary incontinence in women. Danish nationwide cohort studies. Dan Med J 2018; 65 (2); pii: B5447.
8. Baessler K, Christmann-Schmid C, Maher C et al. Surgery for women with pelvic organ prolapse with or without stress urinary incontinence. Cochrane Database Syst Rev 2018; 8.
9. Shah SM, Gaunay GS. Treatment options for intrinsic sphincter deficiency. Nat Rev Urol 2012; p. 177.
10. Ермакова Е.И., Кубицкая Ю.В., Балан В.Е., Аполихина И.А. Биологическая обратная связь в лечении недержания мочи у женщин. Акуш. и гинекол. 2013; 12: 102–5. / Ermakova E.I., Kubitskaia Iu.V., Balan V.E., Apolikhina I.A. Biologicheskaia obratnaia sviaz' v lechenii nederzhaniia mochi u zhenshchin. Akush. i ginekol. 2013; 12: 102–5. [in Russian]
11. Costa AALFD, Vasconcellos IM, Pacheco RL et al. What do Cochrane systematic reviews say about non-surgical interventions for urinary incontinence in women? Sao Paulo Med J 2018; 136 (1): 73–83.
12. Matsuoka PK, Locali RF, Pacetta AM et al. The efficacy and safety of urethral injection therapy for urinary incontinence in women: a systematic review. Clinics (Sao Paulo) 2016; 71 (2): 94–100.
13. Kirchin V, Page T, Keegan PE et al. Urethral injection therapy for urinary incontinence in women. Cochrane Database Syst Rev. Neurourol Urodyn 2018; 37 (7): 2286–7.
14. Dmochowski R, Appell A. Delivery of injectable agents for treatment of stress urinary incontinence in woman evolving techniques. Tech Urol 2008; 7 (2): 110–7.
15. Casteleijn FM, Zwolsman SE, Kowalik CR, Roovers JP. Patients' perspectives on urethral bulk injection therapy and mid-urethral sling surgery for stress urinary incontinence. Int Urogyn J 2018; 29 (9): 1249–57.
16. Zhao Y, Guo X, Lobodasch K et al. Bulking agents - an analysis of 500 cases and review of the literature. Clin Exp Obstet Gynecol 2016; 43 (5): 666–72.
17. Vecchioli-Scaldazza CV, Smaali C, Morosetti C et al. Polyacrylamide hydrogel (Bulkamid®) in female patients of 80 or more years with urinary incontinence. Int Braz J Urol 2014; 40 (1): 37–43.
18. Sokol ER, Karram MM, Dmochowski R. Efficacy and safety of polyacrylamide hydrogel for the treatment of female stress incontinence: a randomized, prospective, multicenter. North American study. J Urol 2014; 192 (3): 843–9.
________________________________________________
1. Monz D, Pons M, Hampel C et al. Patien – repoted impact of urinary incontinence. Results from treatment seeking women in 14 European countries. Maturitas 2005; 52 (2): 25–8.
2. Hampel C, Weinhold D, Benken N et al. Prevalence and Natural History of Female Incontinence. Eur Urol 2007; 32 (Suppl. 2): 3–12.
3. Ermakova E.I., Balan V.E. Urogenital'nye narusheniia u zhenshchin v klimakterii: optimizatsiia metodov lecheniia. Akush. i ginekol. 2013; 3: 85–9.
4. Raz S. Vaginal surgery for stress incontinence. J Am Geriatr Soc 1990; 38: 345–7.
5. Blaivas JG, Olsson CA. Stress incontinence classification and surgical approach. J Urol 1988; 139: 737.
6. Kan D.V. Rukovodstvo po akusherskoi i ginekologicheskoi urologii. 2-e izd., pererab. i dop. M.: Meditsina, 1986; s. 486–95. [in Russian]
7. Hansen MF. Surgical treatment for urinary incontinence in women. Danish nationwide cohort studies. Dan Med J 2018; 65 (2); pii: B5447.
8. Baessler K, Christmann-Schmid C, Maher C et al. Surgery for women with pelvic organ prolapse with or without stress urinary incontinence. Cochrane Database Syst Rev 2018; 8.
9. Shah SM, Gaunay GS. Treatment options for intrinsic sphincter deficiency. Nat Rev Urol 2012; p. 177.
10. Ermakova E.I., Kubitskaia Iu.V., Balan V.E., Apolikhina I.A. Biologicheskaia obratnaia sviaz' v lechenii nederzhaniia mochi u zhenshchin. Akush. i ginekol. 2013; 12: 102–5. [in Russian]
11. Costa AALFD, Vasconcellos IM, Pacheco RL et al. What do Cochrane systematic reviews say about non-surgical interventions for urinary incontinence in women? Sao Paulo Med J 2018; 136 (1): 73–83.
12. Matsuoka PK, Locali RF, Pacetta AM et al. The efficacy and safety of urethral injection therapy for urinary incontinence in women: a systematic review. Clinics (Sao Paulo) 2016; 71 (2): 94–100.
13. Kirchin V, Page T, Keegan PE et al. Urethral injection therapy for urinary incontinence in women. Cochrane Database Syst Rev. Neurourol Urodyn 2018; 37 (7): 2286–7.
14. Dmochowski R, Appell A. Delivery of injectable agents for treatment of stress urinary incontinence in woman evolving techniques. Tech Urol 2008; 7 (2): 110–7.
15. Casteleijn FM, Zwolsman SE, Kowalik CR, Roovers JP. Patients' perspectives on urethral bulk injection therapy and mid-urethral sling surgery for stress urinary incontinence. Int Urogyn J 2018; 29 (9): 1249–57.
16. Zhao Y, Guo X, Lobodasch K et al. Bulking agents - an analysis of 500 cases and review of the literature. Clin Exp Obstet Gynecol 2016; 43 (5): 666–72.
17. Vecchioli-Scaldazza CV, Smaali C, Morosetti C et al. Polyacrylamide hydrogel (Bulkamid®) in female patients of 80 or more years with urinary incontinence. Int Braz J Urol 2014; 40 (1): 37–43.
18. Sokol ER, Karram MM, Dmochowski R. Efficacy and safety of polyacrylamide hydrogel for the treatment of female stress incontinence: a randomized, prospective, multicenter. North American study. J Urol 2014; 192 (3): 843–9.
Авторы
Е.И.Ермакова*
ФГБУ «Национальный медицинский исследовательский центр акушерства, гинекологии и перинатологии им. акад. В.И.Кулакова» Минздрава России. 117997, Россия, Москва, ул. Академика Опарина, д. 4
*ermakova.health@mail.ru
________________________________________________
E.I.Ermakova*
V.I.Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology of the Ministry of Health of the Russian Federation. 117997, Russian Federation, Moscow, ul. Akademika Oparina, d. 4
*ermakova.health@mail.ru