1. Сумерова Н.М., Крижановская А.Н., Пушкарь Д.Ю., Токтар Л.Р. Сексуальные дисфункции у женщин. Вестник РУДН, сер. Медицина. Акушерство и гинекология. 2011;6:380-5 [Sumerova NM, Krizhanovskaya AN, Pushkar' DYU, Toktar LR. Seksual'nye disfunkcii u zhenshchin. Vestnik RUDN, ser. Medicina. Akusherstvo i ginekologiya. 2011;6:380-5 (in Russian)].
2. Reyhani M, Kazemi A, Keshvari M, Farajzadegan Z. Sexual expectations and needs of middle‑aged women: A qualitative study. J Educ Health Promot. 2018;7:49. DOI:10.4103/jehp.jehp_155_17
3. Lindau ST, Schumm LP, Laumann EO, et al. A study of sexuality and health among older adults in the United States. N Engl J Med. 2007;357(8):762-74. DOI:10.1056/NEJMoa067423
4. Sadock BJ, Sadock VA, Ruiz P. Kaplan and Sadock's synopsis of Psychiatry: behavioral sciences/clinical psychiatry. 11th Edition. LWW, 2015.
5. Safarinejad MR. Female sexual dysfunction in a population‑based study in Iran: prevalence and associated risk factors. Int J Impot Res. 2006;18(4):382‑95. DOI:10.1038/sj.ijir.3901440
6. Гурко Г., Щербакова С. Возрастные аспекты синдрома сексуальных дисфункций у женщин. Врач. 2014;6:27-9 [Gurko G, Shcherbakova S. Age-related aspects of female sexual dysfunction. Doctor = Vrach. 2014;6:27-9 (in Russian)].
7. Подзолкова Н.М., Глазкова О.Л. Симптом, синдром, диагноз. Дифференциальная диагностика в гинекологии. 3-е изд., испр. и доп. М.: ГЭОТАР-Медиа, 2014 [Podzolkova NM, Glazkova OL. Simptom, sindrom, diagnoz. Differencial'naya diagnostika v ginekologii. 3-e izd., ispr. i dop. Moscow: GEOTAR-Media, 2014 (in Russian)].
8. Коган М.И., Авадиева Н.Э. Женские сексуальные дисфункции (общие аспекты). Медицинский вестник. 2009;3(472):72-3 [Kogan MI, Avadieva NE. Zhenskie seksual'nye disfunkcii (obshchie aspekty). Medicinskij vestnik. 2009;3(472):72-3 (in Russian)].
9. McKenzie LJ, Carson SA. Human Sexuality and Female Sexual Dysfunction in Danforth’s Obstetrics and Gynecology. 9th ed. Philadelphia, PA: Lippincott Williams & Wilkins, 2003.
10. Андреева Е.Н., Шереметьева Е.В. Проблема женской сексуальности. Проблемы репродукции. 2019;25(3):40-50 [Andreeva EN, Sheremet'eva EV. The problem of female sexuality. Russian Journal of Human Reproduction. 2019;25(3):40‑50 (in Russian)]. DOI:10.17116/repro20192503140
11. Мазуркевич М.В., Фирсова Т.А. Нейрогормональные аспекты полового влечения у женщин. Андрология и генитальная хирургия. 2015;16(1):41-4 [Mazurkevich MV, Firsova TA. Neurohormonal aspects of sexual drive in women. Andrology and Genital Surgery. 2015;16(1):41-4 (in Russian)]. DOI:10.17650/2070-9781-2015-1-41-44
12. Ahmadnia E, Haseli A, Karamat A. Therapeutic interventions conducted on improving women’s sexual satisfaction and function during reproductive ages in Iran: A systematic review. J Mazandaran Univ Med Sci. 2017;27(153):146‑62.
13. Fagan PJ. Sexual Disorders: Perspectives on Diagnosis and Treatment, 2004.
14. Hafizi S, Abbassian A, Tabarrai M, et al. The effect of Jazar supplement on quality of life and sexual function in postmenopausal women: a double-blind, randomized, placebo-controlled trial. Evid Based Complement Alternat Med. 2021;2021:8854182. DOI:10.1155/2021/8854182
15. Abbaspoor Z, Hajikhani NA, Afshari P. Effect of Vitex agnus-castus on menopausal early symptoms in postmenopausal women: a randomized, double blind, placebo–controlled study. J Adv Med Med Res. 2011;1(3)132-40.
16. Bhagavathula AS, Elnour AA, Shehab A. Pharmacovigilance on sexual enhancing herbal supplements. Saudi Pharm J. 2016;24(1):115‑8. DOI:10.1016/j.jsps.2015.01.018
17. Allahtavakoli M, Honari N, Pourabolli I, et al. Vitex Agnus Castus extract improves learning and memory and increases the transcription of estrogen receptor α in hippocampus of ovariectomized rats. Basic Clin Neurosci. 2015;6(3):185‑92.
18. Артымук Н.В., Кондратьева Т.А., Тачкова О.А. Принципы терапии пациенток с бесплодием и недостаточностью лютеиновой фазы менструального цикла. Вопросы гинекологии, акушерства и перинатологии. 2009;8(4):31-5 [Artymuk NV, Kondrat'eva TA, Tachkova OA. Principy terapii pacientok s besplodiem i nedostatochnost'yu lyuteinovoj fazy menstrual'nogo cikla. Voprosy ginekologii, akusherstva i perinatologii. 2009;8(4):31-5 (in Russian)].
19. Сметник В.П., Бутарева Л.Б. Опыт применения фитопрепарата агнукастон (Циклодинон®) у пациенток с недостаточностью функции желтого тела и гиперпролактинемией. Проблемы репродукции. 2005;11(5):50-4 [Smetnik VP, Butareva LB. Opyt primeneniya fitopreparata agnukaston (Ciklodinon®) u pacientok s nedostatochnost'yu funkcii zheltogo tela i giperprolaktinemiej. Problemy reprodukcii. 2005;11(5):50-4 (in Russian)].
20. Wuttke W. Dopaminergic action of extracts of Agnus Castus. Forschende Komplementmed. 1996;3:329-30.
21. Адамов Г.В., Мельников Е.С., Лупанова И.А., и др. Изучение химического состава и дофаминергической активности плодов Витекса священного (Vitex agnus-castus L.). Разработка и регистрация лекарственных средств. 2020;9(3):143-9 [Adamov GV, Melnikov ES, Lupanova IA, et al. Investigation of the chemical composition and dopaminergic activity of the Vitex agnus-castus fruits. Razrabotka i registratsiya lekarstvennykh sredstv = Drug development & registration. 2020;9(3):143-9 (in Russian)]. DOI:10.33380/2305-2066-2020-9-3-143-149
22. Jarry H, Leonhardt S, Gorkow C, Wuttke W. In vitro prolactin but not LH and FSH release is inhibited by compounds in extracts of Agnus castus: direct evidence for a dopaminergic principle by the dopamine receptor assay. Exp Clin Endocrinol. 1994;102(6):448‑54. DOI:10.1055/s-0029-1211317
23. Meier B, Berger D, Hoberg E, et al. Pharmacological activities of Vitex agnus‑castus extracts in vitro. Phytomedicine. 2000;7(5):373‑81. DOI:10.1016/S0944-7113(00)80058-6
24. Heirati SFD, Ozgoli G, KabodMehri R, et al. The 4-month effect of Vitex agnus-castus plant on sexual function of women of reproductive age: A clinical trial. J Educ Health Promot. 2021;10:294. DOI:10.4103/jehp.jehp_63_21
25. Brown D. Vitex agnus castus clinical monograph. Qtry Rev Nat Med. 1994;2:111‑21.
26. Naseri R, Farnia V, Yazdchi K, et al. Comparison of Vitex agnus-castus extracts with placebo in reducing menopausal symptoms: a randomized double-blind study. Korean J Fam Med. 2019;40(6):362-7. DOI:10.4082/kjfm.18.0067
27. Duke JA. The Green Pharmacy Herbal Handbook: Your Comprehensive Reference to the Best Herbs for Healing. New York: St. Martin’s Press, 2000.
28. Nathan M, Scholten R. The complete German commission e monographs: Therapeutic guide to herbal medicines. Ann Intern Med. 1999;130:459.
29. Симрок В.В., Рубан Е.С. Оценка эффективности негормонального растительного препарата Циклодинон у пациенток с нарушениями в гипоталамогипофизарно-яичниковой оси. Репродуктивное здоровье женщины. 2007;3(32):46-8 [Simrok VV, Ruban ES. Ocenka effektivnosti negormonal'nogo rastitel'nogo preparata Ciklodinon u pacientok s narusheniyami v gipotalamogipofizarno-yaichnikovoj osi. Reproduktivnoe zdorov'e zhenshchiny. 2007;3(32):46-8 (in Russian)].

________________________________________________

1. Sumerova NM, Krizhanovskaya AN, Pushkar' DYU, Toktar LR. Seksual'nye disfunkcii u zhenshchin. Vestnik RUDN, ser. Medicina. Akusherstvo i ginekologiya. 2011;6:380-5 (in Russian).
2. Reyhani M, Kazemi A, Keshvari M, Farajzadegan Z. Sexual expectations and needs of middle‑aged women: A qualitative study. J Educ Health Promot. 2018;7:49. DOI:10.4103/jehp.jehp_155_17
3. Lindau ST, Schumm LP, Laumann EO, et al. A study of sexuality and health among older adults in the United States. N Engl J Med. 2007;357(8):762-74. DOI:10.1056/NEJMoa067423
4. Sadock BJ, Sadock VA, Ruiz P. Kaplan and Sadock's synopsis of Psychiatry: behavioral sciences/clinical psychiatry. 11th Edition. LWW, 2015.
5. Safarinejad MR. Female sexual dysfunction in a population‑based study in Iran: prevalence and associated risk factors. Int J Impot Res. 2006;18(4):382‑95. DOI:10.1038/sj.ijir.3901440
6. Гурко Г., Щербакова С. Возрастные аспекты синдрома сексуальных дисфункций у женщин. Врач. 2014;6:27-9 [Gurko G, Shcherbakova S. Age-related aspects of female sexual dysfunction. Doctor = Vrach. 2014;6:27-9 (in Russian)].
7. Podzolkova NM, Glazkova OL. Simptom, sindrom, diagnoz. Differencial'naya diagnostika v ginekologii. 3-e izd., ispr. i dop. Moscow: GEOTAR-Media, 2014 (in Russian).
8. Kogan MI, Avadieva NE. Zhenskie seksual'nye disfunkcii (obshchie aspekty). Medicinskij vestnik. 2009;3(472):72-3 (in Russian).
9. McKenzie LJ, Carson SA. Human Sexuality and Female Sexual Dysfunction in Danforth’s Obstetrics and Gynecology. 9th ed. Philadelphia, PA: Lippincott Williams & Wilkins, 2003.
10. Andreeva EN, Sheremet'eva EV. The problem of female sexuality. Russian Journal of Human Reproduction. 2019;25(3):40‑50 (in Russian). DOI:10.17116/repro20192503140
11. Mazurkevich MV, Firsova TA. Neurohormonal aspects of sexual drive in women. Andrology and Genital Surgery. 2015;16(1):41-4 (in Russian). DOI:10.17650/2070-9781-2015-1-41-44
12. Ahmadnia E, Haseli A, Karamat A. Therapeutic interventions conducted on improving women’s sexual satisfaction and function during reproductive ages in Iran: A systematic review. J Mazandaran Univ Med Sci. 2017;27(153):146‑62.
13. Fagan PJ. Sexual Disorders: Perspectives on Diagnosis and Treatment, 2004.
14. Hafizi S, Abbassian A, Tabarrai M, et al. The effect of Jazar supplement on quality of life and sexual function in postmenopausal women: a double-blind, randomized, placebo-controlled trial. Evid Based Complement Alternat Med. 2021;2021:8854182. DOI:10.1155/2021/8854182
15. Abbaspoor Z, Hajikhani NA, Afshari P. Effect of Vitex agnus-castus on menopausal early symptoms in postmenopausal women: a randomized, double blind, placebo–controlled study. J Adv Med Med Res. 2011;1(3)132-40.
16. Bhagavathula AS, Elnour AA, Shehab A. Pharmacovigilance on sexual enhancing herbal supplements. Saudi Pharm J. 2016;24(1):115‑8. DOI:10.1016/j.jsps.2015.01.018
17. Allahtavakoli M, Honari N, Pourabolli I, et al. Vitex Agnus Castus extract improves learning and memory and increases the transcription of estrogen receptor α in hippocampus of ovariectomized rats. Basic Clin Neurosci. 2015;6(3):185‑92.
18. Artymuk NV, Kondrat'eva TA, Tachkova OA. Principy terapii pacientok s besplodiem i nedostatochnost'yu lyuteinovoj fazy menstrual'nogo cikla. Voprosy ginekologii, akusherstva i perinatologii. 2009;8(4):31-5 (in Russian).
19. Smetnik VP, Butareva LB. Opyt primeneniya fitopreparata agnukaston (Ciklodinon®) u pacientok s nedostatochnost'yu funkcii zheltogo tela i giperprolaktinemiej. Problemy reprodukcii. 2005;11(5):50-4 (in Russian).
20. Wuttke W. Dopaminergic action of extracts of Agnus Castus. Forschende Komplementmed. 1996;3:329-30.
21. Adamov GV, Melnikov ES, Lupanova IA, et al. Investigation of the chemical composition and dopaminergic activity of the Vitex agnus-castus fruits. Razrabotka i registratsiya lekarstvennykh sredstv = Drug development & registration. 2020;9(3):143-9 (in Russian). DOI:10.33380/2305-2066-2020-9-3-143-149
22. Jarry H, Leonhardt S, Gorkow C, Wuttke W. In vitro prolactin but not LH and FSH release is inhibited by compounds in extracts of Agnus castus: direct evidence for a dopaminergic principle by the dopamine receptor assay. Exp Clin Endocrinol. 1994;102(6):448‑54. DOI:10.1055/s-0029-1211317
23. Meier B, Berger D, Hoberg E, et al. Pharmacological activities of Vitex agnus‑castus extracts in vitro. Phytomedicine. 2000;7(5):373‑81. DOI:10.1016/S0944-7113(00)80058-6
24. Heirati SFD, Ozgoli G, KabodMehri R, et al. The 4-month effect of Vitex agnus-castus plant on sexual function of women of reproductive age: A clinical trial. J Educ Health Promot. 2021;10:294. DOI:10.4103/jehp.jehp_63_21
25. Brown D. Vitex agnus castus clinical monograph. Qtry Rev Nat Med. 1994;2:111‑21.
26. Naseri R, Farnia V, Yazdchi K, et al. Comparison of Vitex agnus-castus extracts with placebo in reducing menopausal symptoms: a randomized double-blind study. Korean J Fam Med. 2019;40(6):362-7. DOI:10.4082/kjfm.18.0067
27. Duke JA. The Green Pharmacy Herbal Handbook: Your Comprehensive Reference to the Best Herbs for Healing. New York: St. Martin’s Press, 2000.
28. Nathan M, Scholten R. The complete German commission e monographs: Therapeutic guide to herbal medicines. Ann Intern Med. 1999;130:459.
29. Simrok VV, Ruban ES. Ocenka effektivnosti negormonal'nogo rastitel'nogo preparata Ciklodinon u pacientok s narusheniyami v gipotalamogipofizarno-yaichnikovoj osi. Reproduktivnoe zdorov'e zhenshchiny. 2007;3(32):46-8 (in Russian).

Н.М. Подзолкова1,2, Л.В. Сумятина*1

1 ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России, Москва, Россия;
2 ГБУЗ «Городская клиническая больница им. С.П. Боткина» Департамента здравоохранения г. Москвы, Москва, Россия
*sumyatin@yandex.ru

________________________________________________

Natalia M. Podzolkova1,2, Liliana V. Sumyatina*1

1 Russian Medical Academy of Continuous Professional Education, Moscow, Russia;
2 Botkin Hospital, Moscow, Russia
*sumyatin@yandex.ru