1. Guarino A, Albano F, Ashkenazi S et al. European Society for Paediatric Gastroenterology, Hepatology, and Nutrition. European Society for Paediatric Infectious Diseases Evidence-based Guidelines for the Management of Acute Gastroenteritis in Children in Europe. J Pediatr Gastroenterol Nutr 2008; 46 (Suppl. 2): 81–122.
2. Casburn-Jones AC, Farthing MJG. Management of infectious diarrhea. Gut 2004; 53 (2): 296–305.
3. Hatchette TF, Farina D. Infectious diarrhea: when to test and when to treat. CMAJ 2011; 183: 339–44.
4. Von Sonnenburg F, Tornieporth N, Waiyaki P et al. Risk and aetiology of diarrhoea at various tourist destinations. Lancet 2000; 356: 133–4.
5. DuPont HL. New insights and directions in traveler's diarrhea. Gastroenterol Clinics N Am 2006; 35 (2): 337–53.
6. Phillippe PH de Saussure Management of the Returning Traveler with Diarrhea. Therap Adv Gastroenterol 2009; 2 (6): 367–75.
7. Kollaritsch H, Paulke-Korinek M, Wiedermann U. Traveler's Diarrhea. Infect Dis Clin North Am 2012; 26 (3): 691–706.
8. Javier de la Cabada Bauche, Herbert L DuPont. New Developments in Traveler's Diarrhea. Gastroenterol Hepatol (NY) 2011; 7 (2): 88–95.
9. Mackell S. Traveler's diarrhea in the pediatric population: etiology and impact. Clin Infect Dis. 2005; 41 (Suppl. 8): 547–52.
10. Bartlett JG. Clinical practice. Antibiotic-associated diarrhea. N Engl J Med 2002; 346: 334–9.
11. Alam S, Mushtaq M. Antibiotic associated diarrhea in children. Indian J Pediatr 2009; 46 (6): 491–6.
12. Kim J, Smathers S, Prasad P et al. Epidemiological Features of Clostridium difficile-Associated Disease Among Inpatients at Children’s Hospitals in the United States, 2001–2006. Pediatrics 2008; 122 (6): 1266–70.
13. Langley JM, LeBlanc JC, Hanakowski M, Goloubeva O. The role of Clostridium difficile and viruses as causes of nosocomial diarrhea in children. Infection Control and Hospital Epidemiology 2002; 23 (11): 660.
14. Горелов А.В., Милютина Л.Н., Усенко Д.В. Клинические рекомендации по диагностике и лечению острых кишечных инфекций у детей. Пособие для врачей. М., 2006.
15. Acute diarrhea in adults and children: a global perspective. World Gastroenterology Organisation Global Guidelines, 2012.
16. Острые кишечные инфекции у детей. Учебно-методическое пособие. Под ред. В.Ф.Учайкина. М.: ГОУ ВПО РГМУ, 2005.
17. Bellemare S, Hartling L, Wiebe N et al. Oral rehydration versus intravenous therapy for treating dehydration due to gastroenteritis in children: a meta-analysis of randomised controlled trials. BMC Medicine 2004; 2: 11.
18. Fonseca BK, Holdgate A, Craig JC. Enteral vs intravenous rehydration therapy for children with gastroenteritis: a meta-analysis of randomized controlled trials. Arch Pediatr Adolesc Med 2004; 158 (5): 483–90.
19. Горелов А.В., Усенко Д.В. Ротавирусная инфекция у детей. Вопр. совр. педиатрии. 2008; 7 (6): 78–84.
20. Геппе Н.А., Горелов А.В., Дронов И.А. Проблемы антибактериальной терапии при кишечных инфекциях у детей. Мед. совет. 2011; 5: 22–6.
21. American Academy of Pediatrics. In: Pickering LK, ed. Red Book: 2003 Report of the Committee on Infectious Diseases. 26th ed. Elk Grove Village, IL: American Academy of Pediatrics.
22. Bielaszewska M, Idelevich EA, Zhang W et al. Effects of antibiotics on Shiga toxin 2 production and bacteriophage induction by epidemic Escherichia coli O104:H4 strain. Antimicrob Agents Chemother 2012; 56 (6): 3277–82.
23. Бактериофаги – антибактериальные препараты будущего. Сб. статей. М., 2009.
24. Бактериофаги: биология и практическое применение. Под ред. Э.Каттер, А.Сулаквелидзе. М.: Научный мир, 2012.
25. World Gastroenterology Organization. Probiotics and prebiotics: Practice Guideline 2011. http://www.worldgastroenterology. org/probiotics-prebiotics.html
26. Canani RB, Cirillo P, Terrin GA et al. Probiotics for treatment of acute diarrhea in children: randomised clinical trial of five different preparations. BMJ 2007; 335: 340–7.
27. De Vrese M, Marteau PR. Probiotics and prebiotics: effects on diarrhea. J Nutr 2007; 137 (3 Suppl. 2): 803S–11S.
28. Gaon D, Garcia H, Winter L et al. Effect of Lactobacillus strains and Saccharomyces boulardii on persistent diarrhea in children. Medicina (B Aires) 2003; 63: 293–8.
29. Vandenplas Y, Brunser O, Szajewska H. Saccharomyces boulardii in childhood. Eur J Pediatr 2009; 168 (3): 253–65.
30. Корниенко Е.А. Механизмы воздействия антибиотиков на кишечник, роль Энтерола в профилактике и лечении антибиотик-ассоциированной диареи у детей. Фарматека. 2010; 2: 33–7.
31. Buts JP. Twenty-five years of research on Saccharomyces boulardii trophic effects: updates and perspectives. Dig Dis Sci 2009; 54: 15–8.
32. Blehaut H, Massot J, Elmer GW et al. Disposition kinetics of Saccharomyces boulardii in man and rat. Biopharm Drug Dispos 1989; 10: 353–64.
33. Elmer GW, Moyer KA, Vega R et al. Evaluation of Saccharomyces boulardii forpatients with HIV-related chronic diarrhoea and in healthy volunteers receiving antifungals. Microecol Ther 1995; 25: 23–31.
34. Castaneda C, Garcia E, Santa Cruz M et al. Effects of Saccharomyces boulardii in children with chronic diarrhea, especially cases due to giardiasis. Rev Mex Pueric Pediatr 1995; 2: 12–6.
35. Jabn HU, Ullrich R, Schneider T et al. Immunological and trophical effects of Saccharomyces boulardii on the small intestine in healthy human volunteers. Digestion 1996; 57: 95–104.
36. Castagliuolo I, Riegler MF, Valenick L et al. Saccharomyces boulardii protease mediates Clostridium difficile toxin A and B effects in human colonic mucosa. Infect Immun 1999; 67: 302–7.
37. Girard P, Pansart Y, Lorette I et al. Dose-response relationship and mechanism of action of Saccharomyces boulardii in castor oilinduced diarrhea in rats. Dig Dis Sci 2003; 48: 770–4.
38. Szajewska H et a. Meta-analysis: non-pathogenic yeast S. boulardii in the prevention of antibiotic-associated diarrhea. Alimentary Pharmacol Therapeutics 2005; 22, Issue 5; p. 365–72
39. Buts JP, de Keyser N, de Raedemaeker L. Saccharomyces boulardii enhances rat intestinal enzyme expression by endoluminal release of polyamines. Pediatr Res 1994; 36: 522–7.
40. Turck D, Bernet JP, Marx J et al. Incidence and risk factors of oral antibioticassociated diarrhea in an outpatient pediatric population. J Pediatr Gastroenterol Nutr 2003; 37: 22–6.
41. Grandy G et al. Probiotics in the treatment of acute rotavirus diarrhea. BMC Infectious Diseases 2010; 10: 253.
42. McFarland LV. Meta-analysis of probiotics for the prevention of traveler’s diarrhea. Travel Med Infect Dis 2007; 5: 97–105.

М.К.Бехтерева1, В.В.Иванова2, П.С.Макриди3

1 Отдел кишечных инфекций ФГБУ НИИДИ ФМБА России, Санкт-Петербург;
2 Отдел интенсивной терапии неотложных состояний у детей ФГБУ НИИДИ ФМБА России, Санкт-Петербург;
3 Отдел микроэкологии человека ФГБУ НИИДИ ФМБА России, Санкт-Петербург