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Острое воспаление небных миндалин у детей: анализ причин заболевания и возможностей лечения
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Karpischenko S.A., Kolesnikova O.M. Acute inflammation of the tonsils in children: causes and treatment options. Consilium Medicum. Pediatrics (Suppl.). 2015; 1: 47–49.
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Ключевые слова: острый тонзиллит у детей, часто рецидивирующий тонзиллит, патогенная микрофлора.
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Treatment of acute tonsillitis in children is a serious medical problem. Timely and appropriate therapy can prevent the development of chronic inflammation of the tonsils. In most cases, acute tonsillitis has a viral origin, but long-lasting inflammation of the tonsils joins microbial flora, the elimination of which is the main task of the treatment of tonsillitis.
Key words: acute tonsillitis in children, often recurrent tonsillitis, pathogenic microflora.
2. Iqbal FR, Goh BS, Mazita A. The role of proton pump inhibitors in adenoid hypertrophy in children. Otolaryngol Head Neck Surg 2012; 147 (2): 329–34.
3. Allegrucci M et al. Phenotypic characterization of Streptococcus pneumoniae biofilm development. J Bacteriol 2006; 188 (7): 2325 –35.
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5. McIsaac WJ, Kellner JD, Aufricht P et al. Empirical validation of guidelines for the management of pharyngitis in children and adults. JAMA 2004; 291: 1587–1595. Erratum in: JAMA 2005; 294: 2700.
6. Timon CI, McAllister VA, Walsh MA, Cafferkey MT. Changes in tonsil bacteriology of recurrent acute tonsillitis: 1980 vs 1989. Respir Med 1990; 84: 395–400.
7. Kumai A, Gupta V, Chandra K et al. Clinico bacteriological evaluation of surface and core microflora in chronic tonsillitis. Indian J Otolaryngol Head Neck Surg 2005; 57 (2): 118–20.
8. Mitchelmore IJ, Reilly PG, Hay AJ, Tabaqchali S. Tonsil surface and core cultures in recurrent tonsillitis: prevalence of anaerobes and beta-lactamase producing organisms. Eur J Clin Microbiol Infect Dis 1994; 13 (7): 542–8.
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10. Brook I, Shah K, Jackson W. Microbiology of healthy and diseased adenoids. Laryngoscope 2000; 110: 994–9.
11. Gul M, Okur E, Ciragil P et al. The comparison of tonsillar surface and core cultures in recurrent tonsillitis. Am J Otolaryngol 2007; 28: 173–6.
12. Kasenomm P, Piirsoo A, Kull M et al. Selection of indicators for tonsillectomy in adults with recurrent tonsillitis. BMC Ear Nose Throat Disord 2005; 5: 7.
13. Skoulakis C, Tigiroglou E, Gkarelis K et al. Level of Streptococcus pyogenes in patients with recurrent tonsillitis and tonsillar hypertrophy. Scand J Infect Dis 2008; 40: 899–903.
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15. Uppal K, Bais AS. Tonsillar microflora, superficial surface versus deep. J Laryngol Otol 1989; 103: 175–7.
16. Inci E, Kakakullukcu B, Aygun G, Ozdogan A. Tonsil surface and core microflora in children undergone tonsillectomy for recurrent tonsillitis. Turkish Otolaryngol Arch 2002; 40 (4): 247–51.
17. Zatner AE, Krause M, Stropahl G. Intracellular Persisting Staphylococcus aureus Is the Major Pathogen in Recurrent Tonsillitis. PLoS ONE 2010; 5 (30): 1–16.
18. Lee PK, Schlievert PM. Molecular genetics of pyrogenic exotoxin «superantigens» of group A streptococci and Staphylococcus aureus. Curr Top Microbiol Immunol 1991; 174: 1–19. DOI: 10.1007/978-3-642-50998-8_1.
19. Reinert RR. Streptokokken-Infektionen – Aktuelle Aspekte zur Diagnostik, Prophylaxe und Therapie. 1st ed. Bremen: UNI-MED Science, 2007.
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1. Taylan I, Ozcan I, Mumcuoglu I. Comparison of the Surface and Core Bacteria in Tonsillar and Adenoid Tissue With Beta-Lactamase Production. Indian J Otolaryngol Head Neck Surg 2011; 63 (3): 223–8.
2. Iqbal FR, Goh BS, Mazita A. The role of proton pump inhibitors in adenoid hypertrophy in children. Otolaryngol Head Neck Surg 2012; 147 (2): 329–34.
3. Allegrucci M et al. Phenotypic characterization of Streptococcus pneumoniae biofilm development. J Bacteriol 2006; 188 (7): 2325 –35.
4. Karpishchenko S.A., Kolesnikova O.M. Vozmozhnosti lecheniya ostroy boli v gorle. Vrach. 2014; 2: 19–23. [in Russian]
5. McIsaac WJ, Kellner JD, Aufricht P et al. Empirical validation of guidelines for the management of pharyngitis in children and adults. JAMA 2004; 291: 1587–1595. Erratum in: JAMA 2005; 294: 2700.
6. Timon CI, McAllister VA, Walsh MA, Cafferkey MT. Changes in tonsil bacteriology of recurrent acute tonsillitis: 1980 vs 1989. Respir Med 1990; 84: 395–400.
7. Kumai A, Gupta V, Chandra K et al. Clinico bacteriological evaluation of surface and core microflora in chronic tonsillitis. Indian J Otolaryngol Head Neck Surg 2005; 57 (2): 118–20.
8. Mitchelmore IJ, Reilly PG, Hay AJ, Tabaqchali S. Tonsil surface and core cultures in recurrent tonsillitis: prevalence of anaerobes and beta-lactamase producing organisms. Eur J Clin Microbiol Infect Dis 1994; 13 (7): 542–8.
9. Zhuravlev A.S. Mikrobiologicheskoe obosnovanie effektivnosti razlichnykh sposobov lecheniya bol'nykh s khronicheskim kompensirovannym tonzillitom. Folia Otorhinolaryngologica 2014; 20 (1): 42–8. [in Russian]
10. Brook I, Shah K, Jackson W. Microbiology of healthy and diseased adenoids. Laryngoscope 2000; 110: 994–9.
11. Gul M, Okur E, Ciragil P et al. The comparison of tonsillar surface and core cultures in recurrent tonsillitis. Am J Otolaryngol 2007; 28: 173–6.
12. Kasenomm P, Piirsoo A, Kull M et al. Selection of indicators for tonsillectomy in adults with recurrent tonsillitis. BMC Ear Nose Throat Disord 2005; 5: 7.
13. Skoulakis C, Tigiroglou E, Gkarelis K et al. Level of Streptococcus pyogenes in patients with recurrent tonsillitis and tonsillar hypertrophy. Scand J Infect Dis 2008; 40: 899–903.
14. Azovskova O.V., Kozlov R.S., Krechikova O.I., Ivanchik N.V. Dinamika antibiotikorezistentnosti respiratornykh shtammov Streptococcus pyogenes v Rossii za period 1999–2009 gg. Klin. mikrobiologiya i antimikrob. khimioterapiya. 2012; 14 (4): 309–21. [in Russian]
15. Uppal K, Bais AS. Tonsillar microflora, superficial surface versus deep. J Laryngol Otol 1989; 103: 175–7.
16. Inci E, Kakakullukcu B, Aygun G, Ozdogan A. Tonsil surface and core microflora in children undergone tonsillectomy for recurrent tonsillitis. Turkish Otolaryngol Arch 2002; 40 (4): 247–51.
17. Zatner AE, Krause M, Stropahl G. Intracellular Persisting Staphylococcus aureus Is the Major Pathogen in Recurrent Tonsillitis. PLoS ONE 2010; 5 (30): 1–16.
18. Lee PK, Schlievert PM. Molecular genetics of pyrogenic exotoxin «superantigens» of group A streptococci and Staphylococcus aureus. Curr Top Microbiol Immunol 1991; 174: 1–19. DOI: 10.1007/978-3-642-50998-8_1.
19. Reinert RR. Streptokokken-Infektionen – Aktuelle Aspekte zur Diagnostik, Prophylaxe und Therapie. 1st ed. Bremen: UNI-MED Science, 2007.
ГБОУ ВПО Первый Санкт-Петербургский государственный медицинский университет им. И.П.Павлова Минздрава России. 197022, Россия, Санкт-Петербург, ул. Льва Толстого, д. 6/8
*olga_lozo@mail.ru
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S.A.Karpischenko, O.M.Kolesnikova*
I.P.Pavlov First Saint Petersburg State Medical University of the Ministry of Health of the Russian Federation. 197022, Russian Federation, Saint Petersburg, ul. L'va Tolstogo, d. 6/8
*olga_lozo@mail.ru