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Этиология и особенности течения раневого процесса у новорожденных
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Avanesyan AA, Astamirova TS, Budkevich LI. Etiology and features of the course of the wound process in neonates. Pediatrics. Consilium Medicum. 2021; 1: 13–18. DOI: 10.26442/26586630.2021.1.200807
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Материалы и методы. Проанализирована медицинская документация 147 новорожденных, находившихся на лечении в инфекционных и ожоговом отделениях ДГКБ №9 им. Г.Н. Сперанского. В статье приведены клинические примеры детей первого месяца жизни с ранами различной этиологии.
Заключение. Лечение новорожденных с воспалительными процессами кожи и подлежащих тканей различной этиологии требует мультидисциплинарного подхода с вовлечением специалистов не только хирургического профиля.
Ключевые слова: некроз кожи и мягких тканей, тромбоз сосудов, ожоги, новорожденные
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Introduction. Despite the significant progress made in recent decades in reducing the mortality rate, the risks of adverse outcomes in infectious and inflammatory soft tissue diseases in newborns are still high. The high-risk group consists of children from mothers with a pre-morbid background, as well as premature infants with intrauterine hypoxia and intracranial birth trauma. Traumatization and infection can also occur during medical manipulations (tracheal intubation, vascular catheterization, damage to the baby's skin during obstetrical procedures, etc.). The variety of pathological processes that cause wounds of different etiology is due to the anatomical and physiological features of the skin of newborns. In addition, neonatal skin lesions may be a manifestation of systemic diseases and may themselves be the cause of manifestation.
Materials and methods. Medical records of 147 neonates treated in infectious and burn units of Speransky Children’s City Clinical Hospital №9 were analyzed. Clinical examples of children in the first month of life with wounds of various etiologies are presented.
Conclusion. Treatment of newborn infants with inflammatory processes of the skin and underlying tissues of different etiology requires multidisciplinary approach with the involvement of not only surgical specialists.
Key words: skin and soft tissue necrosis, vascular thrombosis, burns, newborns
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2. Cousins Y. Wound care considerations in neonates. Nursing Standard 2014; 28 (46); 61–70. DOI:10.7748/ns.28.46.61.e8402
3. Neonatal skin and wound care. Brighton and Sussex University Hospitals. 2018. Available at: https://www.bsuh.nhs.uk/wp-content/uploads/sites/5/2016/09/neonatal-skin-and-wound-care-wct-2018.pdf. Accessed: 25.04.2021.
4. Bhatt MD, Ho K, Chan AKC. Disorders of coagulation in the neonate. In: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Basic Principles and Practice. 7th ed. Philadelphia, PA: Elsevier; 2018.
5. Rumiantsev AG, Maschan AA, Zharkov PA, Svirin PV. Federal clinical recommendations on diagnosis, treatment and prevention of thrombosis in children. Moscow, 2015 (in Russian)
6. Bendapudi PK, Robbins A, LeBoeuf N, et al. Persistence of endothelial thrombomodulin in a patient with infectious purpura fulminans treated with protein C concentrate. Blood Adv 2018; 2 (21): 2917–21. DOI: 10.1182/bloodadvances.2018024430
7. Ilina IaIu, Fot EV, Kuzkov VV, Kirov MIu. Sepsis-indutsirovannoe povrezhdenie endotelialnogo glikokaliksa (obzor literatury). Vestnik intensivnoi terapii im. A.I. Saltanova 2019; 2: 32–9 (in Russian) DOI: 10.21320/1818-474X-2019-2-32-39
1 ГБУЗ «Детская городская клиническая больница №9 им. Г.Н. Сперанского» Департамента здравоохранения г. Москвы, Москва, Россия;
2 ФГАОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России, Москва, Россия
*anny271992@mail.ru
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Anna A. Avanesyan*1, Tatiana S. Astamirova1, Liudmila I. Budkevich1,2
1 Speransky Children’s City Clinical Hospital №9, Moscow, Russia;
2 Pirogov Russian National Research Medical University, Moscow, Russia
*anny271992@mail.ru