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Почему педиатра интересует вопрос, родился ли ребенок естественным путем или с помощью операции кесарева сечения?
Почему педиатра интересует вопрос, родился ли ребенок естественным путем или с помощью операции кесарева сечения?
Захарова И.Н., Оробинская Я.В., Бережная И.В., Сугян Н.Г., Дедикова О.В., Малявская С.И., Курбакова Д.М. Почему педиатра интересует вопрос, родился ли ребенок естественным путем или с помощью операции кесарева сечения? Педиатрия. Consilium Medicum. 2024;1:8–14. DOI: 10.26442/26586630.2024.1.202613
© ООО «КОНСИЛИУМ МЕДИКУМ», 2024 г.
© ООО «КОНСИЛИУМ МЕДИКУМ», 2024 г.
________________________________________________
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Аннотация
Кесарево сечение – одна из самых распространенных операций в акушерстве и гинекологии. Однако, несмотря на широкое использование этой процедуры, она не лишена определенных рисков не только для матери, но и для ребенка. В результате операции кесарева сечения (КС) новорожденные не получают целый ряд важных микроорганизмов при прохождении родовых путей матери, что может привести к нарушению развития и функционирования микробной экосистемы ребенка. Микробиота кишечника играет важную роль в поддержании здоровья человека. Она способствует пищеварению, укреплению иммунной системы и синтезу некоторых витаминов. Исследования последних лет показывают, что кишечная микробиота детей, рожденных при помощи КС, отличается от той, которая формируется у детей, рожденных естественным путем. В статье рассмотрим последствия этого различия для здоровья детей, а также возможности коррекции состава кишечной микробиоты у детей после КС. Понимание механизмов формирования и функционирования кишечной микробиоты у этих детей может помочь разработать эффективные стратегии профилактики и лечения различных заболеваний, связанных с нарушением баланса кишечной микробиоты.
Ключевые слова: кесарево сечение, микробиота новорожденного, микробиом, кишечная микробиота
Keywords: cesarean section, newborn microbiota, microbiome, intestinal microbiota
Ключевые слова: кесарево сечение, микробиота новорожденного, микробиом, кишечная микробиота
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Keywords: cesarean section, newborn microbiota, microbiome, intestinal microbiota
Полный текст
Список литературы
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20. Azad MB, Konya T, Maughan H, et al; CHILD Study Investigators. Gut microbiota of healthy Canadian infants: profiles by mode of delivery and infant diet at 4 months. CMAJ. 2013;185(5):385‑94. DOI:10.1503/cmaj.121189
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22. Browne HP, Shao Y, Lawley TD. Mother-infant transmission of human microbiota. Curr Opin Microbiol. 2022;69:102173. DOI:10.1016/j.mib.2022.102173
23. Mold JE, Michaëlsson J, Burt TD, et al. Maternal alloantigens promote the development of tolerogenic fetal regulatory T cells in utero. Science. 2008;322(5907):1562‑5. DOI:10.1126/science.1164511
24. Dominguez-Bello MG, Costello EK, Contreras M, et al. Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns. Proc Natl Acad Sci USA. 2010;107(26):11971‑5. DOI:10.1073/pnas.1002601107
25. Rutayisire E, Huang K, Liu Y, Tao F. The mode of delivery affects the diversity and colonization pattern of the gut microbiota during the first year of infants’ life: a systematic review. BMC Gastroenterol. 2016;16(1):86. DOI:10.1186/s12876‑016‑0498‑0
26. Zhou P, Manoil D, Belibasakis GN, Kotsakis GA. Veillonellae: Beyond Bridging Species in Oral Biofilm Ecology. Front Oral Health. 2021;2:774115. DOI:10.3389/froh.2021.774115
27. Hewitt KM, Mannino FL, Gonzalez A, et al. Bacterial diversity in two Neonatal Intensive Care Units (NICUs). PLoS One. 2013;8(1): e54703. DOI:10.1371/journal.pone.0054703
28. Putignani L, Carsetti R, Signore F, Manco M. Additional maternal and nonmaternal factors contribute to microbiota shaping in newborns. Proc Natl Acad Sci USA. 2010;107(42): E159; author reply E160. DOI:10.1073/pnas.1010526107
29. Biasucci G, Benenati B, Morelli L, et al; Cesarean delivery may affect the early biodiversity of intestinal bacteria. J Nutr. 2008;138(9):1796S‑800S. DOI:10.1093/jn/138.9.1796S
30. Bokulich NA, Chung J, Battaglia T, et al: Antibiotics, birth mode, and diet shape microbiome maturation during early life. Sci Transl Med. 2016;8(343):343ra82. DOI:10.1126/scitranslmed.aad7121
31. Butel MJ, Waligora-Dupriet AJ, Wydau-Dematteis S. The developing gut microbiota and its consequences for health. J Dev Orig Health Dis. 2018;9(6):590‑7. DOI:10.1017/S2040174418000119
32. Salminen S, Gibson GR, McCartney AL, Isolauri E. Influence of mode of delivery on gut microbiota composition in seven year old children. Gut. 2004;53(9):1388‑9. DOI:10.1136/gut.2004.041640
33. Stokholm J, Thorsen J, Chawes BL, et al. Cesarean section changes neonatal gut colonization. J Allergy Clin Immunol. 2016;138(3):881‑9.e2. DOIdoi:10.1016/j.jaci.2016.01.028
34. Nuriel-Ohayon M, Neuman H, Ziv O, et al. Progesterone increases Bifidobacterium relative abundance during late pregnancy. Cell Rep. 2019;27(3):730‑6.e3. DOI:10.1016/j.celrep.2019.03.075
35. Korpela K, Salonen A, Vepsäläinen O, et al. Probiotic supplementation restores normal microbiota composition and function in antibiotic-treated and in caesarean-born infants. Microbiome. 2018;6(1):182. DOI:10.1186/s40168‑018‑0567‑4
36. Azad MB, Konya T, Persaud RR, et al; CHILD Study Investigators. Impact of maternal intrapartum antibiotics, method of birth and breastfeeding on gut microbiota during the first year of life: a prospective cohort study. BJOG. 2016;123(6):983‑93. DOI:10.1111/1471‑0528.13601
37. Korpela K, Helve O, Kolho KL, et al. Maternal Fecal Microbiota Transplantation in Cesarean-Born Infants Rapidly Restores Normal Gut Microbial Development: A Proof-of-Concept Study. Cell. 2020;183(2):324‑34.e5. DOI:10.1016/j.cell.2020.08.047
38. Wilson BC, Butler ÉM, Grigg CP, et al. Oral administration of maternal vaginal microbes at birth to restore gut microbiome development in infants born by caesarean section: A pilot randomised placebo-controlled trial. EBioMedicine. 2021;69:103443. DOI:10.1016/j.ebiom.2021.103443
39. Yektaei-Karin E, Moshfegh A, Lundahl J, et al. The stress of birth enhances in vitro spontaneous and IL‑8‑induced neutrophil chemotaxis in the human newborn. Pediatr Allergy Immunol. 2007;18(8):643‑51. DOI:10.1111/j.1399‑3038.2007.00578.x
40. Shi X, Ma W, Duan S, et al. Single-cell transcriptional diversity of neonatal umbilical cord blood immune cells reveals neonatal immune tolerance. Biochem Biophys Res Commun. 2022;608:14‑22. DOI:10.1016/j.bbrc.2022.03.132
41. Ly NP, Ruiz-Perez B, Onderdonk AB, et al: Mode of delivery and cord blood cytokines: a birth cohort study. Clin Mol Allergy. 2006;4:13. DOI:10.1186/1476‑7961‑4–13
42. Gillis CC, Hughes ER, Spiga L, et al. Dysbiosis-Associated Change in Host Metabolism Generates Lactate to Support Salmonella Growth. Cell Host Microbe. 2018;23(1):54‑64.e6. DOI:10.1016/j.chom.2017.11.006
43. Sevelsted A, Stokholm J, Bønnelykke K, Bisgaard H. Cesarean section and chronic immune disorders. Pediatrics. 2015;135(1): e92‑8. DOI:10.1542/peds.2014‑0596
44. Prentice AM. Breastfeeding in the Modern World. Ann Nutr Metab. 2022;78(Suppl. 2):29‑38. DOI:10.1159/000524354
45. Le Doare K, Holder B, Bassett A, Pannaraj PS. Mother’s Milk: A Purposeful Contribution to the Development of the Infant Microbiota and Immunity. Front Immunol. 2018;9:361. DOI:10.3389/fimmu.2018.00361
46. Stewart CJ, Ajami NJ, O’Brien JL, et al. Temporal development of the gut microbiome in early childhood from the TEDDY study. Nature. 2018;562(7728):583‑8. DOI:10.1038/s41586‑018‑0617‑x
47. Vandenplas Y, Berger B, Carnielli VP, et al. Human Milk Oligosaccharides: 2’-Fucosyllactose (2’-FL) and Lacto-N-Neotetraose (LNnT) in Infant Formula. Nutrients. 2018;10(9):1161. DOI:10.3390/nu10091161
48. Hobbs AJ, Mannion CA, McDonald SW, et al. The impact of caesarean section on breastfeeding initiation, duration and difficulties in the first four months postpartum. BMC Pregnancy Childbirth. 2016;16:90. DOI:10.1186/s12884‑016‑0876‑1
49. Maharlouei N, Pourhaghighi A, Raeisi Shahraki H, et al. Factors Affecting Exclusive Breastfeeding, Using Adaptive LASSO Regression. Int J Community Based Nurs Midwifery. 2018;6(3):260‑71.
50. Dunn AB, Jordan S, Baker BJ, Carlson NS. The Maternal Infant Microbiome: Considerations for Labor and Birth. MCN Am J Matern Child Nurs. 2017;42(6):318‑25. DOI:10.1097/NMC.0000000000000373
51. Juan J, Zhang X, Wang X, et al. Association between Skin-to-Skin Contact Duration after Caesarean Section and Breastfeeding Outcomes. Children (Basel). 2022;9(11):1742. DOI:10.3390/children9111742
52. Karimi FZ, Miri HH, Khadivzadeh T, Maleki-Saghooni N. The effect of mother-infant skin-to-skin contact immediately after birth on exclusive breastfeeding: a systematic review and meta-analysis. J Turk Ger Gynecol Assoc. 2020;21(1):46‑56. DOI:10.4274/jtgga.galenos.2019.2018.0138
53. Ulfa Y, Maruyama N, Igarashi Y, Horiuchi S. Early initiation of breastfeeding up to six months among mothers after cesarean section or vaginal birth: A scoping review. Heliyon. 2023;9(6): e16235. DOI:10.1016/j.heliyon.2023.e16235
54. Lagerberg D, Wallby T, Magnusson M. Differences in breastfeeding rate between mothers delivering by caesarean section and those delivering vaginally. Scand J Public Health. 2021;49(8):899‑903. DOI:10.1177/1403494820911788
55. De Silva D, Halken S, Singh C, et al; European Academy of Allergy, Clinical Immunology Food Allergy, Anaphylaxis Guidelines Group. Preventing food allergy in infancy and childhood: Systematic review of randomised controlled trials. Pediatr Allergy Immunol. 2020;31(7):813‑26. DOI:10.1111/pai.13273
56. Halken S, Muraro A, de Silva D, et al; European Academy of Allergy and Clinical Immunology Food Allergy and Anaphylaxis Guidelines Group. EAACI guideline: Preventing the development of food allergy in infants and young children (2020 update). Pediatr Allergy Immunol. 2021;32(5):843‑58. DOI:10.1111/pai.13496
57. Berseth CL, Johnston WH, Stolz SI, et al. Clinical response to 2 commonly used switch formulas occurs within 1 day. Clin Pediatr (Phila). 2009;48(1):58‑65. DOI:10.1177/0009922808321897
58. De Almagro García MC, Moreno Muñoz JA, Jiménez López J, Rodríguez-Palmero Seuma M. Nuevos ingredientes en fórmulas infantiles. Beneficios sanitarios y funcionales [New ingredients in infant formula. Health and functional benefits]. Nutr Hosp. 2017;34(Suppl. 4):8‑12. [Article in Spanish]. DOI:10.20960/nh.1564
59. Zakharova IN, Orobinskaia IaV, Sugian NG, et al. Breast milk oligosaccharides: what do we know today? Pediatrics. Consilium Medicum. 2022;3:204‑12 (in Russian). DOI:10.26442/26586630.2022.3.201851
60. Reverri EJ, Devitt AA, Kajzer JA, et al. Review of the Clinical Experiences of Feeding Infants Formula Containing the Human Milk Oligosaccharide 2’-Fucosyllactose. Nutrients. 2018;10(10):1346. DOI:10.3390/nu10101346
61. Goehring KC, Marriage BJ, Oliver JS, et al. Similar to Those Who Are Breastfed, Infants Fed a Formula Containing 2’-Fucosyllactose Have Lower Inflammatory Cytokines in a Randomized Controlled Trial. J Nutr. 2016;146(12):2559‑66. DOI:10.3945/jn.116.236919
62. Ramirez-Farias C, Baggs GE, Marriage BJ. Growth, Tolerance, and Compliance of Infants Fed an Extensively Hydrolyzed Infant Formula with Added 2’-FL Fucosyllactose (2’-FL) Human Milk Oligosaccharide. Nutrients. 2021;13(1):186. DOI:10.3390/nu13010186
63. Vázquez E, Van den Abbeele P, Marzorati M, Chow JM, Buck R., The Human Milk Oligosaccharide 2´-Fucosyllactose and The Prebiotic scFOS Have Synergistic Effects Modulating the Infant Gut Microbiota. 5th Nutrition & Growth Conference 2018, Paris
64. Jungersen M, Wind A, Johansen E, et al. The Science behind the Probiotic Strain Bifidobacterium animalis subsp. lactis BB‑12(®). Microorganisms. 2014;2(2):92‑110. DOI:10.3390/microorganisms2020092
65. Gazzolo D, Picone S, Gaiero A, et al. Early Pediatric Benefit of Lutein for Maturing Eyes and Brain-An Overview. Nutrients. 2021;13(9):3239. DOI:10.3390/nu13093239
66. Miranda-Dominguez O, Ramirez JSB, Mitchell AJ, et al. Carotenoids improve the development of cerebral cortical networks in formula-fed infant macaques. Sci Rep. 2022;12(1):15220. DOI:10.1038/s41598‑022‑19279‑1
2. Antoine C, Young BK. Cesarean section one hundred years 1920‑2020: the Good, the Bad and the Ugly. J Perinat Med. 2020;49(1):5‑16. DOI:10.1515/jpm‑2020‑0305
3. Bhatia M, Banerjee K, Dixit P, Dwivedi LK. Assessment of Variation in Cesarean Delivery Rates Between Public and Private Health Facilities in India from 2005 to 2016. JAMA Netw Open. 2020;3(8): e2015022. DOI:10.1001/jamanetworkopen.2020.15022
4. Long Q, Kingdon C, Yang F, et al. Prevalence of and reasons for women’s, family members’, and health professionals’ preferences for cesarean section in China: A mixed-methods systematic review. PLoS Med. 2018;15(10): e1002672. DOI:10.1371/journal.pmed.1002672
5. Yasseen III AS, Bassil K, Sprague A, et al. Late preterm birth and previous cesarean section: a population-based cohort study. J Matern Fetal Neonatal Med. 2019;32(14):2400‑7. DOI:10.1080/14767058.2018.1438397
6. Sotiriadis A, Makrydimas G, Papatheodorou S, et al. Corticosteroids for preventing neonatal respiratory morbidity after elective caesarean section at term. Cochrane Database Syst Rev. 2018;8(8): CD006614. DOI:10.1002/14651858.CD006614.pub3
7. Bäckhed F, Roswall J, Peng Y, et al. Dynamics and Stabilization of the Human Gut Microbiome during the First Year of Life. Cell Host Microbe. 2015;17(5):690‑703. DOI:10.1016/j.chom.2015.04.004
8. Koleva PT, Kim JS, Scott JA, Kozyrskyj AL. Microbial programming of health and disease starts during fetal life. Birth Defects Res C Embryo Today. 2015;105(4):265‑77. DOI:10.1002/bdrc.21117
9. Larabi A, Barnich N, Nguyen HTT. New insights into the interplay between autophagy, gut microbiota and inflammatory responses in IBD. Autophagy. 2020;16(1):38‑51. DOI:10.1080/15548627.2019.1635384
10. Zhou GQ, Huang MJ, Yu X, et al. Early life adverse exposures in irritable bowel syndrome: new insights and opportunities. Front Pediatr. 2023;11:1241801. DOI:10.3389/fped.2023.1241801
11. Espírito Santo C, Caseiro C, Martins MJ, et al. Gut Microbiota, in the Halfway between Nutrition and Lung Function. Nutrients. 2021;13(5):1716. DOI:10.3390/nu13051716
12. Asadi A, Shadab Mehr N, Mohamadi MH, et al. Obesity and gut-microbiota-brain axis: A narrative review. J Clin Lab Anal. 2022;36(5): e24420. DOI:10.1002/jcla.24420
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25. Rutayisire E, Huang K, Liu Y, Tao F. The mode of delivery affects the diversity and colonization pattern of the gut microbiota during the first year of infants’ life: a systematic review. BMC Gastroenterol. 2016;16(1):86. DOI:10.1186/s12876‑016‑0498‑0
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31. Butel MJ, Waligora-Dupriet AJ, Wydau-Dematteis S. The developing gut microbiota and its consequences for health. J Dev Orig Health Dis. 2018;9(6):590‑7. DOI:10.1017/S2040174418000119
32. Salminen S, Gibson GR, McCartney AL, Isolauri E. Influence of mode of delivery on gut microbiota composition in seven year old children. Gut. 2004;53(9):1388‑9. DOI:10.1136/gut.2004.041640
33. Stokholm J, Thorsen J, Chawes BL, et al. Cesarean section changes neonatal gut colonization. J Allergy Clin Immunol. 2016;138(3):881‑9.e2. DOIdoi:10.1016/j.jaci.2016.01.028
34. Nuriel-Ohayon M, Neuman H, Ziv O, et al. Progesterone increases Bifidobacterium relative abundance during late pregnancy. Cell Rep. 2019;27(3):730‑6.e3. DOI:10.1016/j.celrep.2019.03.075
35. Korpela K, Salonen A, Vepsäläinen O, et al. Probiotic supplementation restores normal microbiota composition and function in antibiotic-treated and in caesarean-born infants. Microbiome. 2018;6(1):182. DOI:10.1186/s40168‑018‑0567‑4
36. Azad MB, Konya T, Persaud RR, et al; CHILD Study Investigators. Impact of maternal intrapartum antibiotics, method of birth and breastfeeding on gut microbiota during the first year of life: a prospective cohort study. BJOG. 2016;123(6):983‑93. DOI:10.1111/1471‑0528.13601
37. Korpela K, Helve O, Kolho KL, et al. Maternal Fecal Microbiota Transplantation in Cesarean-Born Infants Rapidly Restores Normal Gut Microbial Development: A Proof-of-Concept Study. Cell. 2020;183(2):324‑34.e5. DOI:10.1016/j.cell.2020.08.047
38. Wilson BC, Butler ÉM, Grigg CP, et al. Oral administration of maternal vaginal microbes at birth to restore gut microbiome development in infants born by caesarean section: A pilot randomised placebo-controlled trial. EBioMedicine. 2021;69:103443. DOI:10.1016/j.ebiom.2021.103443
39. Yektaei-Karin E, Moshfegh A, Lundahl J, et al. The stress of birth enhances in vitro spontaneous and IL‑8‑induced neutrophil chemotaxis in the human newborn. Pediatr Allergy Immunol. 2007;18(8):643‑51. DOI:10.1111/j.1399‑3038.2007.00578.x
40. Shi X, Ma W, Duan S, et al. Single-cell transcriptional diversity of neonatal umbilical cord blood immune cells reveals neonatal immune tolerance. Biochem Biophys Res Commun. 2022;608:14‑22. DOI:10.1016/j.bbrc.2022.03.132
41. Ly NP, Ruiz-Perez B, Onderdonk AB, et al: Mode of delivery and cord blood cytokines: a birth cohort study. Clin Mol Allergy. 2006;4:13. DOI:10.1186/1476‑7961‑4–13
42. Gillis CC, Hughes ER, Spiga L, et al. Dysbiosis-Associated Change in Host Metabolism Generates Lactate to Support Salmonella Growth. Cell Host Microbe. 2018;23(1):54‑64.e6. DOI:10.1016/j.chom.2017.11.006
43. Sevelsted A, Stokholm J, Bønnelykke K, Bisgaard H. Cesarean section and chronic immune disorders. Pediatrics. 2015;135(1): e92‑8. DOI:10.1542/peds.2014‑0596
44. Prentice AM. Breastfeeding in the Modern World. Ann Nutr Metab. 2022;78(Suppl. 2):29‑38. DOI:10.1159/000524354
45. Le Doare K, Holder B, Bassett A, Pannaraj PS. Mother’s Milk: A Purposeful Contribution to the Development of the Infant Microbiota and Immunity. Front Immunol. 2018;9:361. DOI:10.3389/fimmu.2018.00361
46. Stewart CJ, Ajami NJ, O’Brien JL, et al. Temporal development of the gut microbiome in early childhood from the TEDDY study. Nature. 2018;562(7728):583‑8. DOI:10.1038/s41586‑018‑0617‑x
47. Vandenplas Y, Berger B, Carnielli VP, et al. Human Milk Oligosaccharides: 2’-Fucosyllactose (2’-FL) and Lacto-N-Neotetraose (LNnT) in Infant Formula. Nutrients. 2018;10(9):1161. DOI:10.3390/nu10091161
48. Hobbs AJ, Mannion CA, McDonald SW, et al. The impact of caesarean section on breastfeeding initiation, duration and difficulties in the first four months postpartum. BMC Pregnancy Childbirth. 2016;16:90. DOI:10.1186/s12884‑016‑0876‑1
49. Maharlouei N, Pourhaghighi A, Raeisi Shahraki H, et al. Factors Affecting Exclusive Breastfeeding, Using Adaptive LASSO Regression. Int J Community Based Nurs Midwifery. 2018;6(3):260‑71.
50. Dunn AB, Jordan S, Baker BJ, Carlson NS. The Maternal Infant Microbiome: Considerations for Labor and Birth. MCN Am J Matern Child Nurs. 2017;42(6):318‑25. DOI:10.1097/NMC.0000000000000373
51. Juan J, Zhang X, Wang X, et al. Association between Skin-to-Skin Contact Duration after Caesarean Section and Breastfeeding Outcomes. Children (Basel). 2022;9(11):1742. DOI:10.3390/children9111742
52. Karimi FZ, Miri HH, Khadivzadeh T, Maleki-Saghooni N. The effect of mother-infant skin-to-skin contact immediately after birth on exclusive breastfeeding: a systematic review and meta-analysis. J Turk Ger Gynecol Assoc. 2020;21(1):46‑56. DOI:10.4274/jtgga.galenos.2019.2018.0138
53. Ulfa Y, Maruyama N, Igarashi Y, Horiuchi S. Early initiation of breastfeeding up to six months among mothers after cesarean section or vaginal birth: A scoping review. Heliyon. 2023;9(6): e16235. DOI:10.1016/j.heliyon.2023.e16235
54. Lagerberg D, Wallby T, Magnusson M. Differences in breastfeeding rate between mothers delivering by caesarean section and those delivering vaginally. Scand J Public Health. 2021;49(8):899‑903. DOI:10.1177/1403494820911788
55. De Silva D, Halken S, Singh C, et al; European Academy of Allergy, Clinical Immunology Food Allergy, Anaphylaxis Guidelines Group. Preventing food allergy in infancy and childhood: Systematic review of randomised controlled trials. Pediatr Allergy Immunol. 2020;31(7):813‑26. DOI:10.1111/pai.13273
56. Halken S, Muraro A, de Silva D, et al; European Academy of Allergy and Clinical Immunology Food Allergy and Anaphylaxis Guidelines Group. EAACI guideline: Preventing the development of food allergy in infants and young children (2020 update). Pediatr Allergy Immunol. 2021;32(5):843‑58. DOI:10.1111/pai.13496
57. Berseth CL, Johnston WH, Stolz SI, et al. Clinical response to 2 commonly used switch formulas occurs within 1 day. Clin Pediatr (Phila). 2009;48(1):58‑65. DOI:10.1177/0009922808321897
58. De Almagro García MC, Moreno Muñoz JA, Jiménez López J, Rodríguez-Palmero Seuma M. Nuevos ingredientes en fórmulas infantiles. Beneficios sanitarios y funcionales [New ingredients in infant formula. Health and functional benefits]. Nutr Hosp. 2017;34(Suppl. 4):8‑12. [Article in Spanish]. DOI:10.20960/nh.1564
59. Захарова И.Н., Оробинская Я.В., Сугян Н.Г., и др. Олигосахариды грудного молока: что мы знаем о них сегодня? Педиатрия. Consilium Medicum. 2022;3:204‑12 [Zakharova IN, Orobinskaia IaV, Sugian NG, et al. Breast milk oligosaccharides: what do we know today? Pediatrics. Consilium Medicum. 2022;3:204‑12 (in Russian)]. DOI:10.26442/26586630.2022.3.201851
60. Reverri EJ, Devitt AA, Kajzer JA, et al. Review of the Clinical Experiences of Feeding Infants Formula Containing the Human Milk Oligosaccharide 2’-Fucosyllactose. Nutrients. 2018;10(10):1346. DOI:10.3390/nu10101346
61. Goehring KC, Marriage BJ, Oliver JS, et al. Similar to Those Who Are Breastfed, Infants Fed a Formula Containing 2’-Fucosyllactose Have Lower Inflammatory Cytokines in a Randomized Controlled Trial. J Nutr. 2016;146(12):2559‑66. DOI:10.3945/jn.116.236919
62. Ramirez-Farias C, Baggs GE, Marriage BJ. Growth, Tolerance, and Compliance of Infants Fed an Extensively Hydrolyzed Infant Formula with Added 2’-FL Fucosyllactose (2’-FL) Human Milk Oligosaccharide. Nutrients. 2021;13(1):186. DOI:10.3390/nu13010186
63. Vázquez E, Van den Abbeele P, Marzorati M, Chow JM, Buck R., The Human Milk Oligosaccharide 2´-Fucosyllactose and The Prebiotic scFOS Have Synergistic Effects Modulating the Infant Gut Microbiota. 5th Nutrition & Growth Conference 2018, Paris
64. Jungersen M, Wind A, Johansen E, et al. The Science behind the Probiotic Strain Bifidobacterium animalis subsp. lactis BB‑12(®). Microorganisms. 2014;2(2):92‑110. DOI:10.3390/microorganisms2020092
65. Gazzolo D, Picone S, Gaiero A, et al. Early Pediatric Benefit of Lutein for Maturing Eyes and Brain-An Overview. Nutrients. 2021;13(9):3239. DOI:10.3390/nu13093239
66. Miranda-Dominguez O, Ramirez JSB, Mitchell AJ, et al. Carotenoids improve the development of cerebral cortical networks in formula-fed infant macaques. Sci Rep. 2022;12(1):15220. DOI:10.1038/s41598‑022‑19279‑1
________________________________________________
2. Antoine C, Young BK. Cesarean section one hundred years 1920‑2020: the Good, the Bad and the Ugly. J Perinat Med. 2020;49(1):5‑16. DOI:10.1515/jpm‑2020‑0305
3. Bhatia M, Banerjee K, Dixit P, Dwivedi LK. Assessment of Variation in Cesarean Delivery Rates Between Public and Private Health Facilities in India from 2005 to 2016. JAMA Netw Open. 2020;3(8): e2015022. DOI:10.1001/jamanetworkopen.2020.15022
4. Long Q, Kingdon C, Yang F, et al. Prevalence of and reasons for women’s, family members’, and health professionals’ preferences for cesarean section in China: A mixed-methods systematic review. PLoS Med. 2018;15(10): e1002672. DOI:10.1371/journal.pmed.1002672
5. Yasseen III AS, Bassil K, Sprague A, et al. Late preterm birth and previous cesarean section: a population-based cohort study. J Matern Fetal Neonatal Med. 2019;32(14):2400‑7. DOI:10.1080/14767058.2018.1438397
6. Sotiriadis A, Makrydimas G, Papatheodorou S, et al. Corticosteroids for preventing neonatal respiratory morbidity after elective caesarean section at term. Cochrane Database Syst Rev. 2018;8(8): CD006614. DOI:10.1002/14651858.CD006614.pub3
7. Bäckhed F, Roswall J, Peng Y, et al. Dynamics and Stabilization of the Human Gut Microbiome during the First Year of Life. Cell Host Microbe. 2015;17(5):690‑703. DOI:10.1016/j.chom.2015.04.004
8. Koleva PT, Kim JS, Scott JA, Kozyrskyj AL. Microbial programming of health and disease starts during fetal life. Birth Defects Res C Embryo Today. 2015;105(4):265‑77. DOI:10.1002/bdrc.21117
9. Larabi A, Barnich N, Nguyen HTT. New insights into the interplay between autophagy, gut microbiota and inflammatory responses in IBD. Autophagy. 2020;16(1):38‑51. DOI:10.1080/15548627.2019.1635384
10. Zhou GQ, Huang MJ, Yu X, et al. Early life adverse exposures in irritable bowel syndrome: new insights and opportunities. Front Pediatr. 2023;11:1241801. DOI:10.3389/fped.2023.1241801
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Авторы
И.Н. Захарова*1,2, Я.В. Оробинская1,3, И.В. Бережная1,2, Н.Г. Сугян1,4, О.В. Дедикова1, С.И. Малявская5, Д.М. Курбакова5
1ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России, Москва, Россия;
2ГБУЗ г. Москвы «Детская городская клиническая больница им. З.А. Башляевой Департамента здравоохранения г. Москвы», Москва, Россия;
3Поликлиника «Мама и малыш» ГАУЗ МО «Химкинская центральная клиническая больница», Химки, Россия;
4ГАУЗ МО «Химкинская центральная клиническая больница», Химки, Россия;
5ФГБОУ ВО «Северный государственный медицинский университет» Минздрава России, Архангельск, Россия
*zakharova-rmapo@yandex.ru
1Russian Medical Academy of Continuous Professional Education, Moscow, Russia;
2Bashlyaeva Children’s City Clinical Hospital of the Moscow City Health Care Department, Moscow, Russia;
3Mommy and Baby Outpatient clinic of Khimki Central Clinical Hospital, Khimki, Russia;
4Khimki Central Clinical Hospital, Khimki, Russia;
5Northern State Medical University, Arkhangelsk, Russia
*zakharova-rmapo@yandex.ru
1ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России, Москва, Россия;
2ГБУЗ г. Москвы «Детская городская клиническая больница им. З.А. Башляевой Департамента здравоохранения г. Москвы», Москва, Россия;
3Поликлиника «Мама и малыш» ГАУЗ МО «Химкинская центральная клиническая больница», Химки, Россия;
4ГАУЗ МО «Химкинская центральная клиническая больница», Химки, Россия;
5ФГБОУ ВО «Северный государственный медицинский университет» Минздрава России, Архангельск, Россия
*zakharova-rmapo@yandex.ru
________________________________________________
1Russian Medical Academy of Continuous Professional Education, Moscow, Russia;
2Bashlyaeva Children’s City Clinical Hospital of the Moscow City Health Care Department, Moscow, Russia;
3Mommy and Baby Outpatient clinic of Khimki Central Clinical Hospital, Khimki, Russia;
4Khimki Central Clinical Hospital, Khimki, Russia;
5Northern State Medical University, Arkhangelsk, Russia
*zakharova-rmapo@yandex.ru
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