В связи с эпидемической заболеваемостью ожирением количество пациентов, принимающих лекарственные препараты для снижения аппетита и уменьшения массы тела, неуклонно растет. В обзоре представлены вопросы классификации препаратов данной группы, необходимые для врача-кардиолога. Представлены патофизиологические механизмы, ведущие к формированию легочной гипертензии и клапанных пороков сердца на фоне приема анорексигенных средств. Приведены данные эпидемиологических и клинических исследований, посвященных этому вопросу.
The quantity of patients with obesity steadily grows. Many patients accept anorexigenic drugs and drugs for reduction of body mass. In this review classification of anorexigenic drugs and drugs for reduction of body mass are discussed. Also pathophysiological mechanisms formation of pulmonary hypertension and valvular heart disease against reception of anorexigenic drugs and drugs for reduction of body mass are discussed. The article summarizes the available data on epidemiological and clinical trials.
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Авторы
И.Е.Чазова, Е.В.Ильина, С.Н.Терещенко
ФГУ РКНПК, ГОУ ВПО МГМСУ
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I.E.Chazova, E.V.Ilina, S.N.Tereshchenko
FSI Russian cardiology scientific and production complex, Moscow, Moscow state mediko-stomatologic university