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Место блокаторов рецепторов ангиотензина в лечении артериальной гипертензии согласно последним рекомендациям (2013 г.) Европейского общества по гипертонии (ESH) и Европейского общества кардиологов (ESC) по лечению артериальной гипертензии
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Аннотация
В статье приведены данные последних рекомендаций (2013 г.) Европейского общества по гипертонии (ESH) и Европейского общества кардиологов (ESC) по лечению артериальной гипертензии. Особое внимание уделено группе блокаторов рецепторов ангиотензина и одному из их представителей – ирбесартану.
Ключевые слова: артериальная гипертензия, блокаторы рецепторов ангиотензина, ирбесартан, антигипертензивная эффективность.
Ключевые слова: артериальная гипертензия, блокаторы рецепторов ангиотензина, ирбесартан, антигипертензивная эффективность.
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The following article provides the latest recommendations of the European Society of Hypertension (ESH) and the European Society of Cardiology (ESC) 2013 for the treatment of hypertension. Particular attention is given to the group of angiotensin receptor blockers and irbesartan.
Key words: arterial hypertension, angiotensin receptor blockers, irbesartan, antihypertensive efficacy.
Полный текст
Список литературы
1. Чукаева И.И. Что такое приверженность к лечению и что можно сделать для ее улучшения (на примере артериальной гипертонии). Лечебное дело. 2012; 2: 21–7.
2. Рекомендации Европейского общества по гипертонии (ESH) и Европейского общества кардиологов (ESC), 2013 г.
3. Клиническая фармакология. Под ред. В.Г.Кукеса. 4-е изд. М.: ГЭОТАР-Медиа, 2008; с. 392–5.
4. Klag MJ, Whelton PK, Randall BL et al. End-stage renal disease in African American and white men. 16-year MRFIT findings. JAMA 1997; 277: 1293–8.
5. Lea J, Greene T, Hebert L et al. The relationship between magnitude of proteinuria reduction and risk of end-stage renal disease: results of the African American study of kidney disease and hypertension. Arch Intern Med 2005; 165: 947–53.
6. De Zeeuw D, Remuzzi G, Parving HH et al. Albuminuria, a therapeutic target for cardiovascular protection in type 2 diabetic patients with nephropathy. Circulation 2004; 110: 921–7.
7. Schmieder RE, Mann JF, Schumacher H et al. Changes in albuminuria predict mortality and morbidity in patients with vascular disease. J Am Soc Nephrol 2011; 22: 1353–64.
8. Kunz R, Friedrich C, Wolbers M, Mann JF. Meta-analysis: effect of monotherapy and combination therapy with inhibitors of the rennin angiotensin system on proteinuria in renal disease. Ann Intern Med 2008; 148: 30–48.
9. Schmieder RE, Hilgers KF, Schlaich MP, Schmidt BM. Reninangiotensin system and cardiovascular risk. Lancet 2007; 369: 1208–19.
10. Lewis EJ, Hunsicker LG, Clarke WR et al. Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. N Engl J Med 2001; 345: 851–60.
11. Dahlof B, Devereux RB, Kjeldsen SE et al. Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction inhypertension study (LIFE): a randomized trial against atenolol. Lancet 2002; 359: 995–1003.
12. Julius S, Kjeldsen SE, Weber M et al. Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: the VALUE randomised trial. Lancet 2004; 363: 2022–31.
13. Pfeffer MA, Swedberg K, Granger CB et al. CHARM Investigators and Committees. Effects of candesartan on mortality and morbidity in patients with chronic heart failure: the CHARM-Overall programme. Lancet 2003; 362 (9386): 759–66.
14. Wachtell K, Lehto M, Gerdts E et al. Angiotensin II receptor blockade reduces newonset atrial fibrillation and subsequent stroke compared with atenolol: the Losartan Intervention For End Point Reduction in Hypertension (LIFE) study. J Am Coll Cardiol 2005; 45: 712–9.
15. Schmieder RE, Kjeldsen SE, Julius S et al. Reduced incidence of new-onset atrial fibrillation with angiotensin II receptor blockade: the VALUE trial. J Hypertens 2008; 26: 403–11.
16. Ong KT, Delerme S, Pannier B et al. Aortic stiffness is reduced beyond blood pressure lowering by short-term and long-term antihypertensive treatment: a meta-analysis of individual data in 294 patients. J Hypertens 2011; 29: 1034–42.
17. Shahin Y, Khan JA, Chetter I. Angiotensin converting enzymeinhibitors effect on arterial stiffness and wave reflections: a meta-analysis and meta-regression of randomised controlled trials. Atherosclerosis 2012; 221: 18–33.
18. Karalliedde J, Smith A, De Angelis L et al. Valsartan improves arterialstiffness in type 2 diabetes independently of blood pressure lowering. Hypertension 2008; 51: 1617–23.
19. Verdecchia P, Reboldi G, Angeli F et al. Angiotensin-Converting Enzyme Inhibitorsand Calcium Channel Blockers for Coronary Heart Disease and Stroke Prevention. Hypertension 2005; 46: 386–92.
20. Schrader J, Luders S, Kulschewski A et al. MOSES Study Group. Morbidity and mortality after stroke, eprosartan compared with nitrendipine for secondary prevention: principal results of a prospective randomized controlled study (MOSES). Stroke 2005; 36: 1218–26.
21. Reboldi G, Angeli F, Cavallini C et al. Comparison between angiotensin-converting enzyme inhibitors and angiotensin receptor blockers on the risk of myocardial infarction, stroke and death: a meta-analysis. J Hypertens 2008; 26: 1282–9.
22. Blood Pressure Lowering Treatment Trialists’ Collaboration. Effects of different blood-pressure-lowering regimens on major cardiovascular events: results of prospectively-designed overviews ofrandomised trials. Lancet 2003; 362: 1527–35.
2. Рекомендации Европейского общества по гипертонии (ESH) и Европейского общества кардиологов (ESC), 2013 г.
3. Клиническая фармакология. Под ред. В.Г.Кукеса. 4-е изд. М.: ГЭОТАР-Медиа, 2008; с. 392–5.
4. Klag MJ, Whelton PK, Randall BL et al. End-stage renal disease in African American and white men. 16-year MRFIT findings. JAMA 1997; 277: 1293–8.
5. Lea J, Greene T, Hebert L et al. The relationship between magnitude of proteinuria reduction and risk of end-stage renal disease: results of the African American study of kidney disease and hypertension. Arch Intern Med 2005; 165: 947–53.
6. De Zeeuw D, Remuzzi G, Parving HH et al. Albuminuria, a therapeutic target for cardiovascular protection in type 2 diabetic patients with nephropathy. Circulation 2004; 110: 921–7.
7. Schmieder RE, Mann JF, Schumacher H et al. Changes in albuminuria predict mortality and morbidity in patients with vascular disease. J Am Soc Nephrol 2011; 22: 1353–64.
8. Kunz R, Friedrich C, Wolbers M, Mann JF. Meta-analysis: effect of monotherapy and combination therapy with inhibitors of the rennin angiotensin system on proteinuria in renal disease. Ann Intern Med 2008; 148: 30–48.
9. Schmieder RE, Hilgers KF, Schlaich MP, Schmidt BM. Reninangiotensin system and cardiovascular risk. Lancet 2007; 369: 1208–19.
10. Lewis EJ, Hunsicker LG, Clarke WR et al. Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. N Engl J Med 2001; 345: 851–60.
11. Dahlof B, Devereux RB, Kjeldsen SE et al. Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction inhypertension study (LIFE): a randomized trial against atenolol. Lancet 2002; 359: 995–1003.
12. Julius S, Kjeldsen SE, Weber M et al. Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: the VALUE randomised trial. Lancet 2004; 363: 2022–31.
13. Pfeffer MA, Swedberg K, Granger CB et al. CHARM Investigators and Committees. Effects of candesartan on mortality and morbidity in patients with chronic heart failure: the CHARM-Overall programme. Lancet 2003; 362 (9386): 759–66.
14. Wachtell K, Lehto M, Gerdts E et al. Angiotensin II receptor blockade reduces newonset atrial fibrillation and subsequent stroke compared with atenolol: the Losartan Intervention For End Point Reduction in Hypertension (LIFE) study. J Am Coll Cardiol 2005; 45: 712–9.
15. Schmieder RE, Kjeldsen SE, Julius S et al. Reduced incidence of new-onset atrial fibrillation with angiotensin II receptor blockade: the VALUE trial. J Hypertens 2008; 26: 403–11.
16. Ong KT, Delerme S, Pannier B et al. Aortic stiffness is reduced beyond blood pressure lowering by short-term and long-term antihypertensive treatment: a meta-analysis of individual data in 294 patients. J Hypertens 2011; 29: 1034–42.
17. Shahin Y, Khan JA, Chetter I. Angiotensin converting enzymeinhibitors effect on arterial stiffness and wave reflections: a meta-analysis and meta-regression of randomised controlled trials. Atherosclerosis 2012; 221: 18–33.
18. Karalliedde J, Smith A, De Angelis L et al. Valsartan improves arterialstiffness in type 2 diabetes independently of blood pressure lowering. Hypertension 2008; 51: 1617–23.
19. Verdecchia P, Reboldi G, Angeli F et al. Angiotensin-Converting Enzyme Inhibitorsand Calcium Channel Blockers for Coronary Heart Disease and Stroke Prevention. Hypertension 2005; 46: 386–92.
20. Schrader J, Luders S, Kulschewski A et al. MOSES Study Group. Morbidity and mortality after stroke, eprosartan compared with nitrendipine for secondary prevention: principal results of a prospective randomized controlled study (MOSES). Stroke 2005; 36: 1218–26.
21. Reboldi G, Angeli F, Cavallini C et al. Comparison between angiotensin-converting enzyme inhibitors and angiotensin receptor blockers on the risk of myocardial infarction, stroke and death: a meta-analysis. J Hypertens 2008; 26: 1282–9.
22. Blood Pressure Lowering Treatment Trialists’ Collaboration. Effects of different blood-pressure-lowering regimens on major cardiovascular events: results of prospectively-designed overviews ofrandomised trials. Lancet 2003; 362: 1527–35.
Авторы
И.И.Чукаева*, М.В.Соловьева, С.Н.Литвинова
ГБОУ ВПО Российский национальный исследовательский медицинский университет им. Н.И.Пирогова Минздрава России, Москва
*chukaeva@mail.ru
ГБОУ ВПО Российский национальный исследовательский медицинский университет им. Н.И.Пирогова Минздрава России, Москва
*chukaeva@mail.ru
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I.I.Chukaeva*, M.V.Solovieva, S.N.Litvinova
*chukaeva@mail.ru
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