Механизмы мобилизации гемопоэтических предшественников гранулоцитарным колониестимулирующим фактором

1. Shimoda K, Okamura S, Harada N et al. High-frequency granuloid colony-forming ability of G-CSF receptor possessing CD34 antigen positive human umbilical cord blood hematopoietic progenitors. Exp Hematology 1992; 23: 226–8.
2. Shinjo K, Takeshita A, Ohnishi K, Ohno R. Expression of granulocyte colony-stimulating factor receptor increases with differentiation in myeloid cells by a newly devised quantitative flow-cytometric assay. Br J Haematol 1995; 91: 783–94.
3. Ebihara Y, Xu MJ, Manabe A et al. Exclusive expression of G-CSF receptor on myeloid progenitors in bone marrow CD34+cells. Br J Haematol 2000; 109: 153–61.
4. Tsuji K, Ebihara Y. Expression of G-CSF receptor on myeloid progenitors. Leuk Lymphoma 2001; 42 (6): 1351–7.
5. Cutler C, Antin JH. Peripheral blood stem cells for allogenic transplantation: a review. Stem Cells 2001; 19: 108–17.
6. Gyger M, Stuart RK, Perreault C. Immunology of allogeneic peripheral blood mononuclear cells mobilized with granulocyte-colony stimulating factor. Bone Marrow Transplant 2000; 26: 1–16.
7. Tarella C, Benedetti G, Caracciolo D et al. Boyh early and committed haematopoietic progenitors are more frequent in peripheral blood then in bone marrow during mobilization induced by high-dose chemotherapy + G-CSF. Br J Haematol 1995; 91: 535–43.
8. Haas R, Mohle R, Pforsich M et al. Blood-derived autografts collected during granulocyte colony-stimulating factor-enhanced recovery are enriched with early Thy-1+ hematopoietic progenitor cells. Blood 1995; 85: 1936–43.
9. Ципори Д. Роль факторов стромальных клеток (рестриктинов) в микроорганизации кроветворной ткани. Пробл. гематол. 1996; 1: 55–7.
10. Donna D. Evolutionary considerations in hematopoietic development. Ann N-Y AS 1999: 84–91.
11. Kronenwett R, Martin S, Haas R. The Role of Cytokines and Adhesion Molecules for Mobilization of Peripheral Blood Stem Cells. Stem Cells 2000; 18 (5): 320–30.
12. Torok-Storb B et al. Dissecting the marrow microenvironment. ISH-EHA. 1999: 164–9.
13. Prosper F, Stroncek D, McCarthy JB et al. Mobilization and homing of peripheral blood progenitors is related to reversible downregulation of alpha4 beta1 integrin expression and function. J Clin Invest 1998; 101: 2456–67.
14. Mohle R, Murea S, Kirsch M et al. Differential expression of L-selectin, VLA-4, and LFA-1 on CD34+ progenitor cells from bone marrow and peripheral blood during G-CSF-enhanced recovery. Exp Hematol 1995; 23: 1535–42.
15. Papayannopoulou T, Priestley GV, Nakamoto B. Anti-VLA4/VCAM-1-induced mobilization requires cooperative signaling through the kit/mkit ligand pathway. Blood 1998; 91: 2231–9.
16. Mohle R, Moore MA, Nachman RL et al. Transendothelial migration of CD34+ and mature hematopoietic cells: an in vitro study using a human bone marrow endothelial cell line. Blood 1997; 89: 72–80.
17. Oostendorp RA, Spitzer E, Brandl M et al. Evidence for differences in the mechanisms by which antibodies against CD44 promote adhesion of erythroid and granulopoietic progenitors to marrow stromal cells. Br J Haematol 1998; 101: 436–45.
18. Yamaguchi M, Ikebuchi K, Hirayama F et al. Different adhesive characteristics and VLA-4 expression of CD34 (+) progenitors in G0/G1 versus S+G2/M phases of the cell cycle. Blood 1998; 92 (3): 842–8.
19. Fruehauf S, Veldwijk MR, Kramer A et al. Delineation of cell cycle state and correlation to adhesion molecule expression of human CD34+ cells from steady-state bone marrow and peripheral blood mobilized following G-CSF-supported chemotherapy. Stem Cells 1998; 16 (4): 271–9.
20. Kovach NL, Lin N, Yednock T et al. Stem cell factor modulates avidity of a4b1 and a5b1 integrins expressed on hematopoietic cell lines. Blood 1995; 85: 159–67.
21. Levesque J-P, Leavesley DI, Niutta S et al. Cytokines increase human hemopoietic cell adhesiveness by activation of very late antigen (VLA)-4 and VLA-5 integrins. J Exp Med 1995; 181: 1805–15.
22. Prosper F, Stroncek D, McCarthy JB, Verfaillie CM. Mobilization and homing of peripheral blood progenitors is related to reversible downregulation of alpha4 beta1 integrin expression and function. J Clin Invest 1998; 101 (11): 2456–67.
23. Aiuti A, Webb IJ, Bleul C et al. The chemokine SDF-1 is a chemoattractant for human CD34+ hematopoietic progenitor cells and provides a new mechanism to explain the mobilization of CD34+ progenitors to peripheral blood. J Exp Med 1997; 185: 111–20.
24. Mohle R, Bautz F, Rafii S et al. Regulation of Transendothelial Migration of Hematopoietic Progenitor Cells. Ann N-Y AS. 1999; 872: 176–86.
25. Lemoli RM, Tafuri A, Tura S et al. Cycling Status of CD34+ Cells Mobilized Into Peripheral Blood of Healthy Donors by Recombinant Human Granulocyte Colony-Stimulating Factor. Blood 1997; 89 (4): 1189–96.
26. Uchida N, He D, Tsukamoto A. The Unexpected G0/G1 Cell Cycle Status of Mobilized Hematopoietic Stem Cells From Peripheral Blood. Blood 1997; 89 (2): 465–72.
27. Kiel K, Cremer FW, Ehrbrecht E et al. First and second apheresis in patients with multiple myeloma: no differences in tumor load and hematopoietic stem cell yield. Bone Marrow Transplant 1998; 21 (11): 1109–15.
28. Abe T, Makimoto A, Kawano Y et al. Intra-apheresis recruitment of blood progenitor cells in children. Transfusion 1998; 38 (10): 944–50.
29. Cytokine responses of hematopoietic progenitor cell, ISH-EHA 1999: 51–5.
30. Ogawa M., Matsunaga T. Humoral regulation of hematopoietic stem cells. Ann N-Y AS. 1999: 17–23.
31. Papayannopoulou T. Hematopoietic Stem/Progenitor Cell Mobilization: a continuing quest for etiologic mechanisms. Ann N-Y AS. 1999: 187–95.
32. Pruijt JF, Fibbe WE, Opdenakker G et al. Prevention of interleukin-8-induced mobilization of hematopoietic progenitor cells in rhesus monkeys by inhibitory antibodies against the Metalloproteinase gelatinase B (MMP-9). Proc Natl Acad Sci USA 1999; 96: 10863–8.
33. Watanabe T, Kawano Y, Kanamaru S et al. Endogenous interleukin-8 (IL-8) surge in granulocyte colony-stimulating factor-induced peripheral blood stem cell mobilization. Blood 1999; 93 (4): 1157–63.
34. Higa GM, DeVore RF, Auber ML et al. Biological and clinical correlates after chemotherapy and granulocyte colony-stimulating factor administration. Pharmacotherapy 1998; 18 (1): 1–8.
35. Philpott NJ, Prue RL, Marsh JC et al. G-CSF-mobilized CD34 peripheral blood stem cells are significantly less apoptotic then unstimulated peripheral blood CD34 cells: role of G-CSF as survival factor. Br J Haematol 1997; 97 (1): 146–52.
36. Anthony RS, McKelvie ND, Cunningham AJ et al. Flow cytometry using annexin V can detect early apoptosis in peripheral blood stem cell harvests from patients with leukaemia and lymphoma. Bone Marrow Transplant 1998; 21 (5): 441–6.
37. Vetillard J, Drouet M, Neildez-nguyen TMA et al. Interleukine-8 acts as a strong peripheral blood granulocyte-recruiting agent rather then as a hematopoietic progenitor cell-mobilizing factor. J Hematoter Stem Cell Res 1999; 8: 365–79.
38. Владимирская Е.Б., Масчан А.А., Румянцев А.Г. Апоптоз и его роль в развитии опухолевого роста. Гематол. и трансфузиол. 1997; 42 (5): 4–9.
39. Maianski NA, Mul FP, van Buul JD et al. Granulocyte colony-stimulating factor inhibits the mitochondria-dependent activation of caspase-3 in neutrophils. Blood 2002; 99 (2): 672–9.

С.А.Румянцев, Д.Н.Балашов, А.Г.Румянцев

ФГУ Федеральный научно-клинический центр детской гематологии, онкологии и иммунологии Росздрава, Москва